ライフサイエンスコーパス: fully

1 In this work, we present a fully 3D-printed module for attenuated total reflection

2 esensitization of GluK1/GluK2 heteromers and fully abolishes the desensitization of GluK1/GluK5 heter

3 A fully active state is achieved when G(s) is coupled to G

4 nts who had the option of using at least one fully active, approved antiretroviral drug in at least o

5 ncorporate local environmental conditions or fully address how the spatial arrangement of habitat pat

6 nal density functional theory studies, which fully address multi-spin-state reactivity.

7 rg model describing spins on a lattice, with fully adjustable anisotropy of the nearest-neighbour spi

8 h >0.5-1.0 nmol/L compared with >1.0 nmol/L [fully adjusted HR (95% CI): 1.04 (0.92, 1.17)].

9 fifth percentile (ie, highest mortality) of fully adjusted mortality, 60% were located in 3 states:

10 In the fully adjusting model, compared with women who never or

11 anging the degree of oxidation, varying from fully aggregated over graphitic domains to intercalated

12 show that Nb((1-) (x) ()) Ti(x) S(3) can be fully alloyed across the entire composition range from t

13 letal radiologists performed measurements on fully and semiautomated segmented 3D MRI models to asses

14 al strategy has never been demonstrated in a fully aquatic animal, where sensory cues used for orient

15 her reduced tetrahydroisoquinoline (THIQ) or fully aromatized IQ natural products.

16 t this system, the RAS has not been explored fully as a druggable target.

17 om various binarization methods has not been fully assessed.

18 Conclusion The fully automated anatomic localization and classification

19 Conclusion: A fully automated data-driven motion-compensation approach

20 A fully automated detection and grading network based on d

21 el within a complex 3D cell environment in a fully automated HTS workflow.

22 A fully automated integrated analytical platform that incl

23 Fully automated measurements were compared using Pearson

24 The proposed fully automated method was useful for predicting IDH mut

25 We have developed a fully automated microfluidic RT-qPCR system for rapid qu

26 Bio-Rad Laboratories has developed a fully automated multiplex bead-based assay for the detec

27 nds GeneXpert MTB/RIF Ultra (Xpert Ultra), a fully automated PCR assay, as the initial tuberculous me

28 ance and enables further implementation in a fully automated platform for ESI-MS-based high-throughpu

29 Our fully automated system achieved levels of accuracy compa

30 ies accurately from small blood volumes in a fully automated system.

31 ny physiologically-relevant environment in a fully-automated fashion, this method can augment and pot

32 To address this deficit, we developed a fully-automated robotic screening platform that provided

33 The deep learning model allowed for fully automatic and robust segmentation of GA on CFIs.

34 ty maps which was tested by the Phenix based fully automatic method.

35 tween the 2 treatment groups measured by the fully automatic segmentation algorithm was 0.072+/-0.035

36 prehensive evaluation of methods that detect fully automatically the glottal midline.

37 Accordingly, ablation of both Rac1 and Rac2 fully averted the increased progression of KRas(G12D) -d

38 ditions, the protonated phosphate groups are fully back-exchanged in the source, while the exchanged

39 ggesting that it is possible in principle to fully biochemically reconstitute the sequential processe

40 A helically twisted, fully BNB-embedded PAH 11 was prepared by combining 2 wi

41 t" which occurs if the two polymers can form fully-bonded small oligomers by virtue of the number of

42 The active sites of RFC are fully bound to adenosine 5'-triphosphate (ATP) analogs,

43 the dynamics of epidemics, they struggle to fully capture the geospatial dynamics and factors drivin

44 on corneal microstructure, we introduce and fully characterize a nearly-incompressible transversely

45 tly refers to joint commitment, but does not fully characterize it.

46 Both the complexes have been fully characterized by several spectroscopic techniques

47 Whereas many such states are fully characterized by symmetries(2), interacting quantu

48 cognitive state in ways that have yet to be fully characterized.

49 hose components are well studied but not yet fully characterized.

50 nger-dependent behavioral plasticity are not fully characterized.

51 tment for severe, uncontrolled asthma is not fully characterized.

52 mponent self-assembled LMWG hydrogel and was fully characterized.

53 se to an acute bout of exercise has not been fully characterized.

54 3) , MoS(2) /MoO(2) hybrid, and MoS(2) , are fully characterized.

55 aspases regulate GC B cell fate has not been fully characterized.

56 lecular origins of this action are yet to be fully clarified.

57 contribution of this mechanism is still not fully clear in humans.

58 on DNA is complete and the DNA entry gate is fully closed.

59 erent areas of diagnostics, they are not yet fully commercialized.

60 ent, "stand-alone" cell death mechanism that fully compensates for the absence of apoptosis in antivi

61 displaying a wide range of dysfunction, from fully competent to completely incompetent.

62 orous case-by-case assessments are needed to fully comprehend the consequences of MRED use.

63 ncrease at a remarkable rate, the dream of a fully comprehensive computational model of a living cell

64 ion that previous policy discussions did not fully consider.

65 However, date fruit and seeds have not been fully considered as potential functional food ingredient

66 e mechanism for lattice expansion is in fact fully consistent with heat-induced thermal expansion dur

67 (15)N backbone fast time-scale dynamics are fully consistent, demonstrating that fast fluctuations a

68 eats all data points as independent and thus fully contributing to the result.

69 An additional advantage of our fully convolutional architecture is that it allows for t

70 the state-of-the-art DL models including the fully convolutional network (FCN), SegNet, Dilated-Net,

71 anastomotic strictures using a novel type of fully covered metal stent (FCSEMS).

72 pre-PETM oceanic DIC inventory, we provide a fully data-driven estimate of the PETM carbon source.

73 rical and dimensional disorder models with a fully data-driven intrinsic network-level analysis (intr

74 by instead exposing chitosan, the partly or fully deacetylated form of chitin.

75 The results fully define AKI-associated dedifferentiation programs,

76 lae Additional research is necessary to more fully define the utility of WB for the serodiagnosis of

77 tional mouse HSCs ex vivo for >1 month under fully defined albumin-free conditions.

78 aracteristics of the mutant viruses were not fully defined.

79 ue significance of albuminuria has yet to be fully defined.

80 The precise etiology of CS is not fully defined.

81 l-specificity of tauopathy thus remain to be fully defined.

82 regulate this dynamic process have not been fully defined.

83 ergens, such as Alternaria alternata, is not fully defined.

84 A new class of bio-based fully degradable block polyesters are pressure-sensitive

85 that sustain EC heterogeneity have not been fully delineated.

86 the [Ni(4)(NP(t)Bu(3))(4)](+/0) clusters and fully delocalized, spin-correlated electrons.

87 , a lack of rapid diagnostic tests which can fully describe TB resistance patterns is a major challen

88 It is also challenging to fully describe the critical cellular events that drive o

89 actory sensory neurons (OSNs) have yet to be fully determined.

90 -pathology practice will necessarily require fully digital imaging platforms, an overhaul of legacy i

91 s than predicted among age-cohorts that were fully-eligible and partly-eligible for 4CMenB, respectiv

92 r proper functioning of FtsH as its deletion fully eliminated the proteolytic activity of FtsH.

93 )-furanone, allowed us for the first time to fully elucidate the isomeric structures of the MW 212 OS

94 nd the epidemiology of frailty remains to be fully elucidated in a real-world surgical population.

95 lying these ABO effects on VWF have not been fully elucidated, it seems likely that they are mediated

96 by which FlrC regulates transcription is not fully elucidated.

97 >= + 5.50 spherical equivalent) has not been fully elucidated.

98 rmal lineages to drive sorting have not been fully elucidated.

99 velopment of phage therapies, have yet to be fully elucidated.

100 d neuronal pathways implicated have not been fully elucidated.

101 nities and challenges for optogenetics to be fully embraced in cardiology are also discussed.

102 uctured, but retains flexibility even in the fully engaged state.

103 corresponded to when astrocyte endfeet more fully ensheath vessels.

104 s of these local regrowths have not yet been fully established and main concerns include high postope

105 Even in the absence of fully established risk prediction schemes and outcome st

106 the responsible mechanisms have not yet been fully established.

107 2015, and Dec 31, 2018, and 75 patients were fully evaluable for toxicity.

108 to inhibit pathologic fibrosis has not been fully evaluated.

109 seudodegeneracy, but they cannot be a priory fully excluded for any system.

110 -fast low-RAM k-mer-based database search to fully exhaustive gapped DNA alignment, to best fit their

111 ies were lower in white patients but did not fully explain outcomes differences.

112 -)A(38) cross-loop interaction but failed to fully explain the means by which s(2)C(32) restricts I(3

113 These differences could not be fully explained by blood doses and dose rates, which wer

114 To fully exploit this method, we must move towards new allo

115 cal potential as a lead structure is not yet fully exploited.

116 aces to create oxygen vacancies has not been fully explored.

117 navirus disease 2019 (COVID-19) has not been fully explored.

118 of GSK3 in synaptic plasticity has not been fully explored.

119 s for materials discovery that have not been fully explored.

120 ver, the molecular activators and inhibitors fully fitting this versatile model remain elusive in pig

121 which shows that, in specific contexts, the fully flattened average approach provides higher statist

122 full-cell-configuration LIBs, in particular fully flexible/stretchable LIBs, are outlined in detail.

123 that had been experimentally established as fully flowering or nonflowering.

124 a pharmacological blocker and when CFTR was fully functional.Conclusions: Enhancing the activity of

125 The developed theoretical framework can be fully generalized to other emergent layered materials.

126 orcine small intestinal mucus collected from fully-grown pigs for studying colloidal transport of sub

127 ith key examples, and future developments to fully harness the potential of light-induced protein deg

128 Dupilumab is a fully human antibody to interleukin-4 receptor alpha tha

129 A CAR designated FHVH33-CD8BBZ contains a fully human heavy-chain variable domain (FHVH) plus 4-1B

130 ssed the safety and efficacy of belimumab, a fully human IgG1 monoclonal antibody targeting the cytok

131 Osocimab is a long-acting, fully human monoclonal antibody that inhibits factor XIa

132 patients with Covid-19, we investigated two fully human, neutralizing monoclonal antibodies against

133 ar to serve as a sound source microphone for fully implantable hearing technology such as CIs.

134 -step tutorials as well as tutorial data are fully incorporated in the web application.

135 ning SARS-CoV-2 infection status, based on a fully independent set of indicators, that can help confi

136 ally no inhibition, whereas the bivalent IgG fully inhibits beta-tryptase activity in a hinge-depende

137 hting the future research needed to inform a fully integrated and predictive biology that accounts fo

138 By providing a fully integrated framework and evaluation of the impacts

139 nd a micromachined chemoresistive gas sensor fully integrated into a device that communicates wireles

140 uting to diversity, equity, and inclusion is fully integrated into the core mission of our institutio

141 "anatometabolic" information associated with fully integrated PET/MRI.

142 custom-printed circuit board into a compact, fully integrated, and portable system to conduct real-ti

143 Its internal structure is fully interpretableand is faithful to underlying chemist

144 Although we found no fully invariant OMA-selective neuron, we discovered a po

145 ications of TP53 allelic state have not been fully investigated in MDS or any other cancer type.

146 We present the first 3D fully kinetic simulations of laser driven sheath-based i

147 with persistent neurological deficits is not fully known, mitochondrial dysfunction is a key componen

148 specific types of visual information are not fully known.

149 rectly measure Syt1-membrane interaction and fully map the site-binding energetics of Syt1 both in th

150 y, we used a set of unnatural amino acids to fully map the substrate preferences of GrB, demonstratin

151 iation processes from icy cometary bodies to fully melted iron meteorites with isotopic affinities to

152 amino acids were indistinguishable from the fully modified enzyme, suggesting that interactions betw

153 nctional single-sensing resistors as well as fully monolithically integrated e-skin devices.

154 e companion results of a non-hydrostatic and fully nonlinear numerical model.

155 h the exception of reduced tillage, is never fully offset.

156 is includes delivering face-to-face programs fully online for at least part of the upcoming academic

157 Multidimensional techniques that combine fully or partially orthogonal characterization methods i

158 irected synthesis has been used to prepare a fully pai-conjugated cyclic porphyrin octamer, composed

159 the use of a small number of measurements to fully parameterize a regulatory circuit and quantify its

160 design concept and its ability to achieve a fully passive and broadband wave control.

161 otypes distinct from UTX mutation, including fully penetrant cleft palate, mandible hypoplasia and de

162 is destabilized when the activation loop is fully phosphorylated but is again stabilized with ATP-Mg

163 notion that simple C-patch preference is not fully predictive of hnRNPK localization within transcrip

164 ecall response beyond antibody treatment and fully protected against anaphylaxis.

165 ate and oceans, and informed the creation of fully protected deep-water areas in the Galapagos Marine

166 ith tetramannosyl-H-phosphonate provided the fully protected PLM anchor.

167 merous globally devastating diseases without fully protective vaccines, particularly human immunodefi

168 llenge to design quantum neural networks for fully quantum learning tasks.

169 nced imaging methods and quasi-classical and fully quantum theory, we found that a synchronous moveme

170 cal and engineering fields will be needed to fully realize the promise of OoCs for fundamental and tr

171 nal microbiome science in humans has not yet fully realized its clinical potentials.

172 dered mesoporous materials have not yet been fully realized, due to their limited accessibility of in

173 With the potential fully realized, such materials could one day transform t

174 hage infection and resistance have yet to be fully realized.

175 ages the initiation of feeding and drinking (fully recapitulating the symptoms of gastric distension)

176 ounds were left unmated or singly mated in a fully reciprocal design to males from the same three gen

177 knots with their mirror image partners in a fully reciprocal setting.

178 However, many cancers are not fully recognized via NK cell receptors.

179 scherichia coli and paired that model with a fully reconstituted in vitro system to examine the capab

180 Using this technology, 24,752 synapses were fully reconstructed in CA1, revealing that most of them

181 h proven/probable COVID-19, 45 (96%) of whom fully recovered and 2 who died.

182 Of the 7 intubated at baseline, 4/7 were fully recovered off oxygen, 2/7 were still hospitalized,

183 ction is only significant when the enzyme is fully reduced, and fumarate is absent.

184 eezing was lower after PRF conditioning than fully reinforced fear (FRF) conditioning, despite an equ

185 Within 14 ms, new vesicles are recruited and fully replenish the docked pool, but this docking is tra

186 Cingulate and prefrontal regions did not fully replicate.

187 genous tracers-as is standard in BBB studies-fully represents blood-to-brain transport.

188 0 siRNA blocked Th1 infiltration but did not fully rescue microglial activation and white matter inju

189 Such inhibition is fully rescued by cholesterol replenishment in a concentr

190 Ubiquitous expression of GALCLAMP1 fully rescues the phenotype of the GALC-deficient mouse

191 he clearance of the bacterial mutant without fully rescuing the long-lasting colonization of the muta

192 al sensitivities, absent in therapy naive or fully resistant cells, suggesting the potential for new

193 g by BH3 mimetics was performed in CLL cells fully resistant to venetoclax due to CD40-mediated induc

194 ICU scenario, inter-regional transfers could fully resolve bed shortfalls.

195 this variation is an important, but not yet fully resolved question in ecology.

196 and the group's evolutionary history is not fully resolved.

197 ith different size duplications has not been fully resolved.

198 t has become clear that ARV therapy does not fully restore health, leaving individuals at elevated ri

199 connectivity to baseline levels, but did not fully restore memory performance nor its associations wi

200 e phases of equal duration and amplitude and fully restored (unipolar-equivalent response) when the d

201 d spontaneous macrophage regeneration, which fully restored original macrophage distributions and mor

202 These phenotypes were fully restored to those of the wild type when dksA mutat

203 CDO(2) Oxygen content in arterial blood was fully restored with acclimatisation to 4330 m, but concu

204 SAP2 silencing fully restores mortality of the mosquitoes, whereas SAP2

205 rtant for the initiation of RNA synthesis is fully retracted, which leaves space in the active-site c

206 ly exposed cells for up to 1 month failed to fully reverse the transcriptional and phenotypic effects

207 These gating changes could be fully reversed by acute CaMKII inhibition (AIP [autocamt

208 nts are lifted, thus providing a generic and fully reversible method of manipulating effective symmet

209 Such fully reversible plasticity is predominantly governed by

210 = 0.003) and a score of sphingomyelins with fully saturated sphingoid-fatty acid pairs (RR Q4 versus

211 ated life-history syndromes, we selected 559 fully sequenced accessions of the model annual species A

212 he perfect acoustic insulation provided by a fully shut single-glazed window in ideal conditions.

213 etent and olaparib-resistant cancers, making fully small-molecule-induced synthetic lethality an inno

214 However, all six CCTA mutants were fully soluble, which implies a relationship between inso

215 alysis also determines the deviations from a fully stable-state distribution.

216 significantly greater for semistructured vs fully structured interviews.

217 ) (Cu(81)), was successfully synthesized and fully studied by X-ray crystallography, X-ray photoelect

218 rrelation with clinical outcome has not been fully studied.

219 the asymmetric construction of C-O bonds at fully substituted carbon centers in the synthesis of chi

220 myelinated mice in which glial cells cannot fully support axons metabolically.

221 DFT calculations fully support the experimental data and demonstrate the

222 This is fully supported by a recent spin-polarized density funct

223 promise for therapeutic use, even 1-18 alone fully suppressed viremia in HIV-1-infected humanized mic

224 The rate of resistance decay to become fully susceptible from moderate-intensity resistance too

225 ures of electron-phonon coupling to specific fully symmetric optical modes during the buildup of a th

226 gly, the domain remains unfolded until it is fully synthesized, without collapsing into molten globul

227 This fully synthetic and modular therapeutic platform could b

228 use this vaccine platform to rapidly produce fully synthetic MVA (sMVA) vectors co-expressing SARS-Co

229 ew, easily accessible method for calculating fully three-dimensional displacement and 3D surface trac

230 Our fully three-dimensional simulations highlight the crucia

231 Our concept offers a practical, all-optical, fully three-dimensional tomography of electronic structu

232 To contribute more fully to theory and practice, these reported experiences

233 Furthermore, we conducted the so far largest fully transgenic CRISPR screen in any metazoan organism,

234 attention to nanomedicine, however, has not fully translated into clinical utilization and patient b

235 d identify a new reference scheme capable of fully typing all isolates.

236 ts, we developed PHI1, a BRAF inhibitor that fully uncovers the allosteric site.

237 aviours and individual relationships to more fully understand responses to intergroup encounters.

238 It is therefore important to fully understand the characteristics of UVR and the prin

239 es to manage COIs, allowing the committee to fully understand the context of the public speakers' com

240 cts over longer time periods is necessary to fully understand the effects of tree diversity on ecolog

241 y timely and important, but also critical to fully understand the function(s) of rationalization.

242 It is crucial that we more fully understand the indirect effects of GPCR-targeted d

243 ure translational studies are needed to more fully understand the neural mechanisms underlying gamma-

244 and-application of digestate is essential to fully understand the trade-offs between alternatives.

245 multidisciplinary approach, (c) ensuring AYA fully understand their condition and have resources they

246 eading to chronicity of pruritus are not yet fully understood and it is not known whether these mecha

247 re stimulated by such diverse stimuli is not fully understood but may partly rely on cellular changes

248 However, it is not fully understood how plants control light-dependent FAS

249 network architectures exists, but cannot be fully understood without attention to the environmental

250 The pathophysiology of disease is not fully understood, and it may vary by presentation and cl

251 nals by which YAP is activated are still not fully understood, but its activation is known to affect

252 ding mechanical properties, however, are not fully understood, nor is it understood how microstructur

253 tions, but the associated mechanisms are not fully understood.

254 by PZA, its mechanisms of action are not yet fully understood.

255 -specific differences in GAG binding are not fully understood.

256 n, and the mechanisms of the disease are not fully understood.

257 tin in maintaining cell-cell adhesion is not fully understood.

258 logic and metabolic aspects of tumors is not fully understood.

259 th over timescales less than a month are not fully understood.

260 its interplay with dopamine release are not fully understood.

261 cogenic effect of Arg882His in DNMT3A is not fully understood.

262 tion of these two signaling pathways are not fully understood.

263 d the peripheral immune system remains to be fully understood.

264 tance, but the underlying mechanisms are not fully understood.

265 iphosphate (ADP) on flagellar beating is not fully understood.

266 al operation of neuronal interactions is not fully understood.

267 upporting mechanisms of this process are not fully understood.

268 lycolysis in liver cancer progression is not fully understood.

269 d Nogo-A is presented intercellularly is not fully understood.

270 l death in Huntington's disease (HD) are not fully understood.

271 e role of NIPP1 in tissue homeostasis is not fully understood.

272 es, stomata, and pavement cells-is still not fully understood.

273 protein structure and dynamics is still not fully understood.

274 sms by which this integration occurs are not fully understood.

275 metabolic control of these processes is not fully understood.

276 ulation by bacterial compounds are still not fully understood.

277 he microbial community response has not been fully understood.

278 osolic calcium fluctuations are hitherto not fully understood.

279 y and the dynamics of PIC components are not fully understood.

280 dynamics underlying these phenomena are not fully understood.

281 ir expression patterns and functions are not fully understood.

282 y translates into autoimmune disease are not fully understood.

283 ticularly during cardiac remodeling, are not fully understood.

284 ary infection and severity of disease is not fully understood.

285 onents contribute to their formation are not fully understood.

286 mechanisms of virulence attenuation are not fully understood.

287 mmation, its overall regulation is still not fully understood.

288 d semiconducting polymers are far from being fully understood.

289 ch controls this core kinase cassette is not fully understood.

290 ecifics of virus-vector interactions are not fully understood.

291 vation of defence reduces growth are not yet fully understood.

292 the cancer nucleus becomes misshapen is not fully understood.

293 garding deamination target selection are not fully understood.

294 pathology in Alzheimer's disease (AD) is not fully understood.

295 governing the dynamics of CaMKII is not yet fully understood.

296 to perform simple operations and thus do not fully utilize the potential of the Maker Movement.

297 he Bio-Rad MFI was positive in 83.7% of HCWs fully vaccinated against rubella.

298 wo commonly used vitamers, was developed and fully validated in analytical ranges, adjusted to their

299 adults, but none of these questionnaires is fully validated.

300 The rZIKV recovered from these mice remained fully virulent in a second passage in mice.