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1 memory B cells as well as the production of fully human antibodies.
2 sets the stage for using E. coli to produce fully human antibodies.
4 b phage display library, we have generated a fully human antibody (A12) that binds to the IGF-IR with
5 effective and safe immunotherapeutic drugs, fully-human antibodies affinity-matured in a healthy hos
7 antibodies (that are rapidly convertible to fully human antibodies) and have fully functional humora
8 rated timelines necessitate the discovery of fully human antibodies as biotherapeutics using transgen
10 hesis clinically, we developed (89)Zr-5B1, a fully human, antibody-based radiotracer targeting tumor-
12 latory approval of panitumumab (Vectibix), a fully human antibody directed against epidermal growth f
15 in which maytansinoid (DM1) was linked to a fully human antibody IgG78 through an uncleavable SMCC l
19 e the identification and characterisation of fully human antibody MEDI-579, which binds with high aff
21 onoclonal antibodies, allowing the design of fully human antibodies of any specificity and for divers
22 immunoglobulin G1 Fc region to construct the fully human antibody scFv-FcC21, which recognized tumors
25 protein, which yielded a large collection of fully human antibodies that were characterized for bindi
28 nomics and with methods now in place to make fully human antibodies, the potential of antibodies as v
29 ional engineering methodology for generating fully human antibody therapeutics from murine mAbs produ
30 n enables the mice to generate high affinity fully human antibodies to multiple antigens, including h
31 een used to generate numerous high-affinity, fully human antibodies to targets in multiple disease in
32 14 patients with metastatic melanoma using a fully human antibody to cytotoxic T-lymphocyte antigen-4
35 mor necrosis factor alpha, we have generated fully human antibodies with 59, 46, and 45 substitutions