ライフサイエンスコーパス: functional cell

1 ions, subject to the complexities of a fully functional cell.

2 transition of genetic information to a fully functional cell.

3 easome system is essential for maintaining a functional cell.

4 g to repopulate the alveolar epithelium with functional cells.

5 ocyte maturation to CD4 single positive (SP) functional cells.

6 cells with either cDNA alone resulted in non-functional cells.

7 mammals have limited capacity to regenerate functional cells.

8 ia HITI provides high cell yields and highly functional cells.

9 tude but prevents their differentiation into functional cells.

10 or replace damaged liver tissue with healthy functional cells.

11 nversion, and an inability to produce mature functional cells.

12 ic investigation of optically trapped single functional cells.

13 propose a possible explanation for these non-functional cells.

14 neral mechanism to eliminate differentiated, functional cells.

15 s to gastrulation; together with evidence of functional cell adhesion and development within an envel

16 Functional cell adhesion and leukocyte transmigration as

17 ledge from developmental biology to generate functional cells and tissues that could be used for rege

18 atode populations lacking defined classes of functional cells, and for genetic screens.

19 e recombinase (Cre)-mediated excision led to functional, cell- and tissue-specific loss of alpha7 nAC

20 cellular activity in a hemagglutination (HA) functional cell assay of bacterial adhesion.

21 d calcium fluctuations may form the basis of functional cell assemblies.

22 selective and dynamic control of distributed functional cell assemblies.

23 efficient nucleation of fiber subunits into functional, cell-associated amyloid.

24 The presence of functional, cell-associated IL-1 alpha activity in infec

25 Taken together, our identification and functional cell-based analyses of pathogenic variants in

26 The functional cell-based assay Receptor Selection and Ampli

27 In this study, we sought to develop a novel functional cell-based assay that relies on passive sensi

28 Using a functional cell-based assay, we have identified two nove

29 Ab response, a bridging ELISA, as well as a functional cell-based assay, were constructed.

30 LCN leads to increased cell-cell adhesion in functional cell-based assays and disruption of cell pola

31 This includes functional cell-based assays and the evaluation of molec

32 In addition, most functional cell-based assays designed to characterize th

33 ptor kinase interacting ArfGAP 1) gene using functional cell-based assays involving coexpression of G

34 We found that functional cell-based assays of three point mutants affe

35 To test this hypothesis, we have utilized a functional cell-based endocytosis assay and identified t

36 were designed and assessed for inhibition of functional cell-based Gli1-mediated transcription and se

37 ructure-based physicochemical separation and functional cell-based potency assays.

38 presents a new tool for rapid measurement of functional cell-based responses and parallel separation

39 A functional cell-based screen identified 3-(4-chloropheny

40 In the present study, a high-throughput, functional, cell-based assay for identifying Maxi-K chan

41 nist activity using a chimeric receptor in a functional, cell-based, high-throughput assay.

42 hat such cells may ultimately predominate if functional cells become exhausted.

43 will contribute a needed tool for furthering functional cell biology experiments in Cnidaria.

44 vide a reference platform for structural and functional cell biology.

45 Because functional cells cannot be deprived of ATP, we have knoc

46 an ionically tight interface necessary for a functional cell-cell channel.

47 If Cx34.7 forms functional cell-cell channels between cones, it would pr

48 ssociated mutation, Ser-85-Cys (S85C), forms functional cell-cell channels in paired Xenopus oocytes.

49 Functional cell-cell communication developed between WB

50 Here we show that functional cell-cell interaction between NPCs and NSCs t

51 tinct tissue-resident immune cells that form functional cell circuits with structural cells.

52 Z progenitor cells may be one anatomical and functional cell class.

53 These results suggest that a limited set of functional cell classes emerges in macaque prefrontal co

54 IJ (RIIIJ), reliably identified six discrete functional cell classes.

55 and programmed cell death (PCD) to produce a functional cell corpse.

56 orphological localization to the synapse and functional cell culture assays, but their role in embryo

57 of the fact that HEI-C-depleted cells retain functional cell cycle checkpoints, as these cells arrest

58 be2S slows down APC substrate degradation in functional cell-cycle extracts.

59 a means for understanding RNA regulation of functional cell diversity.

60 by a continuous replacement of short-lived, functional cells during chronic MCMV infection.

61 tivity is not responsible for the paucity of functional cells even in end-stage liver disease.

62 egulate the gammadelta T cell maturation and functional cell fate decision.

63 proposed device was loaded and cultured with functional cells for drug response investigation and org

64 ve major potential as an unlimited source of functional cells for many biomedical applications; howev

65 cols aimed at generating clinically safe and functional cells for retinal diseases face challenges su

66 t has become a promising strategy to produce functional cells for therapeutic purposes.

67 iology field is the ability to produce fully functional cells from induced pluripotent stem cells (iP

68 eding behaviour by dynamic reorganization of functional cell groups in the hypothalamus.

69 Strategies to expand functional cells have focused on discovering and control

70 Pertussis toxin-treated Th2 cells were functional cells, however, and when directly instilled i

71 erating B-cells express lower levels of some functional cell identity genes, suggesting that prolifer

72 ism and transcriptional programs that govern functional cell identity.

73 an integrate into the embryo and form mature functional cells in the animal.

74 tability and potential to differentiate into functional cells in vitro (hepatocytes) and in vivo (hep

75 e-cell RNA sequencing (scRNA-seq), assessing functional cell integration in vitro into a mature RPE m

76 lico models that accurately reflect a whole, functional cell is an ongoing challenge in biology.

77 A functional cell is requisite for TSWV infection and cell

78 However, its role in mature functional cells is poorly studied.

79 lready organized state, can suffice to yield functional cells is uncertain.

80 This feature facilitated the coassembly of functional cell-like hybrid vesicles from giant dendrime

81 on the availability of these factors in the functional cell lines employed.

82 In most cases, limitations in functional cell longevity will necessitate periodic repl

83 rocess during which fully differentiated and functional cells lose aspects of their identity while ga

84 Varicella-zoster virus (VZV) encodes a functional cell membrane Fc receptor called glycoprotein

85 This study aimed to identify functional cell membrane proteins that promote HCC tumor

86 lar bioenergetics is proposed that occurs in functional cells not exposed to catastrophic DNA damage.

87 rompted in vitro efforts to produce the main functional cells of the liver: hepatocyte-like cells (He

88 ow efficiently they may be differentiated to functional cells of various lineages.

89 an easy and rapid method for engineering of functional, cell-permeable peptides and demonstrates the

90 ntiation and establishment of structural and functional cell polarity; components of the apical micro

91 rived lymphoid compartments contained normal functional cell populations as determined by the presenc

92 static tumor cells provides a framework of 8 functional cell programs that coexist or anticorrelate.

93 his observation was confirmed in a series of functional (cell proliferation, survival, migration and

94 F-kappaB activation was not due to a lack of functional cell/protein because NF-kappaB was appropriat

95 ely integrate to translate pMHC stimuli into functional cell responses.

96 s compared with their parental mitochondrial-functional cells (rho(+)).

97 ese techniques will be useful in identifying functional cell-specific binding motifs and contribute t

98 m underlying the activation of the transient functional cell states remain largely unexplored.

99 differences in gene regulation across fluid functional cell states within cell types.

100 ial, suggesting that OPCs exist in different functional cell states, and that age-associated states m

101 ce of protein-level measurements to identify functional cell states.

102 f protein-level measurements for identifying functional cell states.

103 ee across behavior, oscillatory network, and functional cell states.

104 d expression of genes encoding components of functional cell structures were often observed indicatin

105 Thus, functional cell subsets may differ not only in the curre

106 uggesting that this marker does not identify functional cell subsets that produce serum interleukin-4

107 stent with the hypothesis that the number of functional cell surface alpha7 nAChRs is controlled indi

108 polymerase chain reaction, S1 nuclease, and functional cell surface binding studies showed that norm

109 pe 1 (HIV-1) coreceptor CCR5 (CCR5 -/-) lack functional cell surface CCR5 molecules and are relativel

110 ellular compartments, resulting in a loss of functional cell surface channel.

111 derivatives, can stabilize DR5 and increase functional cell surface DR5 levels, resulting in enhance

112 al requirement for N-linked glycosylation in functional cell surface expression of D1 and D5 dopamine

113 te that Kvbeta1 differentially regulates the functional cell surface expression of myocardial I(to,f)

114 transmembrane proteins RTP1 and RTP2 promote functional cell surface expression of ORs expressed in H

115 anti-DLL4 treatment reduced T cell mRNA and functional cell surface expression of the chemokine rece

116 alyzed the role of N-linked glycosylation in functional cell surface expression of the D1 and D5 dopa

117 s, but not of TCR-alpha chains, assembly and functional cell surface expression of the TCR-CD3 comple

118 the PKD1L3 and PKD2L1 is necessary for their functional cell surface expression.

119 haplotype, resulting in the formation of two functional cell surface heterodimers, HLA-DR2a (DRA*0101

120 haplotype, resulting in the formation of two functional cell surface heterodimers, HLA-DR2a (DRA*0101

121 losterism between hLHR protomers, indicating functional cell surface hLHR dimers.

122 s IL-22 and prevents binding of IL-22 to the functional cell surface IL-22R complex, which consists o

123 s (HD) by measuring in these neutrophils (i) functional cell surface markers, including CD16, CD62L,

124 protein tyrosine phosphatases (RPTPs) are bi-functional cell surface molecules.

125 rom laboratory mice because of the lack of a functional cell surface receptor required for virus entr

126 , these data show that mouse DESC1 encodes a functional cell surface serine protease that may have im

127 lication error positive in both alleles lack functional cell surface TGF-beta type I (RI) and type II

128 Nanobodies targeting the tip of functional cell-surface CdrA molecules could be used to

129 The number of functional cell-surface NMDARs in cortical neurons incre

130 ear whether primary afferent neurons express functional cell-surface opioid receptors.

131 te that human and murine neutrophils express functional cell-surface P2X7R, which leads to ATP-induce

132 ls, indicating that the 210-kDa protein is a functional cell-surface receptor on type II cells.

133 rized a cell line, CTLL-EPO-R, that contains functional cell-surface receptors for both EPO and IL-2.

134 Insights into the complexity of the functional cell-surface-protein repertoire (surfaceome)

135 s can be genetically modified to overexpress functional, cell-surface Fas ligand (FasL) by adenovirus

136 ust a simple barrier for gas exchange, but a functional cell that protects alveolar epithelium from i

137 d cells but instead is upregulated on highly functional cells that have recently received antigenic s

138 t cell differentiation and the production of functional cells, tissues, and organs.

139 ertheless be some chance that LTD converts a functional cell to a non-functional one; in contrast, th

140 ents a valuable opportunity to replenish the functional cells to the heart.

141 cular disease that relies on the delivery of functional cells to their target site.

142 as imaged by two-photon microscopy permitted functional cell type annotation.

143 ng hematopoietic system, no direct link to a functional cell type has been made.

144 nglion cells as a previously uncharacterized functional cell type in the HSPC niche.

145 Grid cells, the most abundant functional cell type in the MEC, have hexagonally arrang

146 We uncovered a novel functional cell type that preferentially emerged in the

147 These suggest the existence of a novel functional cell type within the gland, that the basal/my

148 cent methodological advances uncovered a new functional cell type, the superhub, that is predicted to

149 This study provides the first functional cell type-specific and spine type-specific co

150 situ paving the way for further spatial and functional cell-type classification.

151 Our findings underscore the importance of functional cell-type evaluation during stepwise differen

152 Functional cell types (FCTs) that encode similar task fe

153 ir capacity to differentiate into mature and functional cell types after transplantation.

154 nt clustering neurons into transcriptomic or functional cell types and characterizing the differences

155 tiation of immature blast cells into mature, functional cell types and lineages of the immune system.

156 of airway-like cysts with persistent loss of functional cell types and parenchymal architecture.

157 ve as a unique avenue for generating diverse functional cell types for biomedical research and therap

158 ating human cells into specific homogeneous, functional cell types is challenging.

159 nduced pluripotent stem cells to defined and functional cell types is essential for future clinical a

160 urons contribute to the spiking behaviour of functional cell types of MEC neurons, such as grid cells

161 nto hepatocytes and cholangiocytes, the main functional cell types of the liver.

162 s that direct stem cell differentiation into functional cell types remains a major challenge in the f

163 icellular organisms is the specialization of functional cell types through the process of differentia

164 Here, we explore using functional cell types to refine single-cell models by gr

165 reproduce themselves and differentiate into functional cell types, attract much interest as potentia

166 tivational control, composed of at least two functional cell types, one signaling for motivational va

167 h the activity of differentiated hippocampal functional cell types, which conjunctively encoded diffe

168 eal carcinoma susceptibility genes and their functional cell types, which improves the understanding

169 le behavior, making it difficult to classify functional cell types.

170 ells (TACs) that differentiate into specific functional cell types.

171 ll naive hESCs fail to differentiate towards functional cell types.

172 ly target and manipulate genetically defined functional cell types.

173 descendants that differentiate into distinct functional cell types.

174 operative in mature duct cells during which functional cells undergo "ductal retrogression" to form

175 LAM is an essential structural entity for a functional cell wall and, consequently, that the biosynt

176 f beta-lactam antibiotics, suggesting that a functional cell wall is required for Pls secretion from

177 whether mango peel is a potential source of functional cell wall polymers.

178 ich posits that heterogeneity stems from non-functional cell wall synthesis machinery, while the seco

179 not need to resist osmotic challenges and a functional cell wall was not detected in these pathogens

180 odulate mitochondrial activity to maintain a functional cell wall when subjected to stresses.

181 onses to drought depend on the presence of a functional cell wall.

182 act covalently and noncovalently to form the functional cell wall.