ライフサイエンスコーパス: fungal

1 bor a distinct microbial community with high fungal abundance, which differs from the surrounding sea

2 sly indicated and a hypothesized model of AM fungal aerial dispersal mechanisms is presented.

3 h could improve predictions regarding how AM fungal aerial dispersal varies by species.

4 There was no relationship between fungal airway presence and steroid dose, asthma severity

5 The tremorgenic fungal alkaloid paxilline (PAX) is a commonly used speci

6 mechanism underlying ATP release induced by fungal allergens and suggests a possible therapeutic use

7 inflammation induced by protease-containing fungal allergens, such as Alternaria alternata, is not f

8 Alleles at fungal allorecognition loci are highly polymorphic, fall

9 We detected 171 fungal amplicon sequence variants (ASVs), 70 from the ai

10 They hold promise as a system to study fungal and animal evolution, but we lack genetic tools f

11 We characterized fungal and bacterial diversity within pieces of deadwood

12 In addition, CRS with fungal and non-fungal infections also demonstrated a sig

13 In the absence of fertilization, fungal and total eukaryotic community compositions expos

14 The intestinal microbiota comprises diverse fungal and viral components, in addition to bacteria.

15 l as detection and identification of various fungal and viral diseases.

16 depressant, anti-bacterial, anti-viral, anti-fungal, and anti-cancer drugs.

17 ides a summary of currently known bacterial, fungal, and oomycete pathogen effectors that induce biot

18 also uncovered, a subset of which suggested fungal antibiotic production.

19 This fungal antigen contributes to immune activation and repr

20 e findings provide insights into the role of fungal association and the ancestral gene repertoire in

21 ntally altering field arbuscular mycorrhizal fungal associations by silencing the Sym-pathway gene Na

22 ted skin was often colonized by a variety of fungal, bacterial and algal species that imparted variab

23 to fungi, potentially revealing sex-specific fungal-bacterial-host dynamics in A. aegypti.

24 counting for an organism's sex when studying fungal-bacterial-host dynamics.

25 Fungal bicyclo[2.2.2]diazaoctane indole alkaloids repres

26 ironments not only contribute to filamentous fungal biofilm maturation but also drive resistance to a

27 unknown mechanistic link between filamentous fungal biofilm physiology and contemporary antifungal dr

28 PV-1 could be a valuable tool to investigate fungal biogeography and the host-pathogen interactions i

29 Fungal bioluminescence is a fascinating natural process,

30 ly eliminated the DON levels and toxicogenic fungal biomass as quantified by Tri5 DNA content.

31 ed in decreased disease symptoms and reduced fungal biomass in the host banana plants.

32 e mitigation effects on mycotoxin levels and fungal biomass, and the clove oil flavor residues on mal

33 Fungal biomass, richness, and oxidative enzyme potential

34 n approaches to identify patients at risk of fungal bloodstream infections for pre-emptive therapeuti

35 e Kennedy pathway, exhibits decreased kidney fungal burden in systemically infected mice.

36 -treated mice had improved survival, reduced fungal burden, increased lung concentrations of proinfla

37 tive group, probably due to a lower systemic fungal burden.

38 paired Th17 cell differentiation, and higher fungal burden.

39 s by up to 73%, and successfully reduced the fungal burdens in a Caenorhabditis elegans infection mod

40 Ca(2+) and the presence of fully functioning fungal Ca(2+) homeostatic/signaling machinery.

41 h those who possess a clear understanding of fungal cell architecture and drug resistance mechanisms.

42 ry metabolites, metabolism of simple sugars, fungal cell wall deconstruction, biofilm formation, anti

43 As this pathway is critical for fungal cell wall integrity, the hexosamine biosynthesis

44 1 responds to NO stress by strengthening the fungal cell wall, and by causing over-accumulation of me

45 Key drivers of hyperinflammation induced by fungal cell walls in CGD are still incompletely defined.

46 key component of arthropod exoskeletons and fungal cell walls, is endogenously produced by fishes an

47 mmation in CGD mice in the early response to fungal cell walls, likely by a dysregulated feed-forward

48 Although interactions between pDC and fungal cells were not detected, pDCs regulated neutrophi

49 highly dependent on the growth status of the fungal cells.

50 nce elements are highly diverse across these fungal centromeres.

51 Fungal challenge assays on leaves and fruits showed that

52 Accelerated fungal clearance in the combination treatment group was

53 bility and either early or late survival, or fungal clearance.

54 Fungal co-infection is a recognised complication of resp

55 studies did not identify or report bacterial/fungal coinfection (85/140; 61%).

56 ents were reported as experiencing bacterial/fungal coinfection during hospital admission.

57 adiation was able to reduce the formation of fungal colonies.

58 gillosis, chronic necrotizing aspergillosis, fungal colonization, and allergic bronchopulmonary asper

59 patterns and processes between bacterial and fungal communities across different habitats.

60 of the main drivers of ectomycorrhizal (EM) fungal communities along elevation and environmental gra

61 he assembly mechanisms of soil bacterial and fungal communities among and within islands.

62 dulation of gastrointestinal and nutritional fungal communities and inspect their impact on metabolic

63 and functional traits in shaping rhizosphere fungal communities and tested the robustness of these re

64 ycobiota composition and that changes in the fungal communities can aggravate metabolic diseases.

65 n the diversity, activity and adaptations of fungal communities in the deep oceanic crust from ~10 to

66 and root traits were stronger predictors of fungal communities than leaf traits.

67 Fungal communities that persist with chronic N depositio

68 Trait relationships with fungal communities were primarily driven by interactions

69 ere ambient N deposition was high suggesting fungal communities were pushed beyond an environmental s

70 a persistent influence on the development of fungal communities, but that sod additions diminished th

71 ents in molecular studies of root-associated fungal communities, suggesting that an evaluation of the

72 plant symbiotic arbuscular mycorrhizal (AM) fungal communities.

73 orces (drift or stochastic dispersal) act on fungal community assembly in leaves and roots early in h

74 onmental filters interact to drive plant and fungal community assembly, but their combined effects ar

75 Yet our ability to link fungal community composition to ecosystem functioning is

76 specific root length, in driving rhizosphere fungal community composition, demonstrating the potentia

77 of +5 degrees C, and compared bacterial and fungal community compositions after the incubation.

78 We compared fungal community compositions of bulk soils differing by

79 y the three-species mixture, had distinct AM fungal community compositions, while cereal rye and fora

80 Wheat straw addition increased the fungal community diversity, whereas the bacterial divers

81 HTS revealed the presence of a more diverse fungal community in the air and snow of Livingston Islan

82 Fungal community structure and function responses to N e

83 had a stronger effect on bacterial (but not fungal) community composition, and induced greater funct

84 tand the oral microbiome have focused on its fungal component.

85 robiota, which includes bacterial, viral and fungal components; the microbiota has a leading role in

86 soil C : N ratio were the primary drivers of fungal composition in the Oe and A1/A2 horizons, respect

87 utrophil responses are critical for clearing fungal conidia from the host airways prior to establishi

88 (CgCOM1) developmental gene involved in the fungal conidial and appressorium formation, to restrict

89 Similar to their fungal counterparts, coexisting bacterial communities as

90 a carbonate-enriched biomass-free ureolytic fungal culture supernatant.

91 Fungal culture was focused towards detection of filament

92 h serves as a "toggle switch" to control the fungal decision between infecting the plant or prolifera

93 Here we examine which traits best explain fungal decomposition ability by combining detailed trait

94 Further, we identified a pair of fungal desaturase homologs which contained either an Ile

95 The BcJAR1 gene was deleted and its roles in fungal development and pathogenesis were investigated us

96 M5-mediated H3K4 demethylation in regulating fungal development and pathogenesis.

97 PK signalling pathways and further regulates fungal development, DON production and plant infection i

98 IGS in silencing the expression of essential fungal developmental genes to inhibit the growth of path

99 etween those tolerant and susceptible to the fungal disease ash dieback.

100 Fusarium head blight (FHB), a fungal disease caused by Fusarium species that produce f

101 8%; 53% and 31% in patients with and without fungal disease, respectively (P: 0.0387).

102 Some patients may develop invasive fungal diseases (IFDs) during initial chemotherapy, whic

103 Fungal diseases are responsible for the deaths of over 1

104 th malignancy transmission and parasitic and fungal diseases.

105 Our data challenge the perception of fungal dispersal as risky, wasteful, and beyond control

106 s are required to understand the dynamics of fungal dispersal within and beyond Antarctica.

107 development of cryptococcal disease and the fungal dissemination to the CNS.

108 Lower fungal diversity and bacteria : fungi ratios in EM-domin

109 Here, we examined soil bacterial and fungal diversity and community compositions across a 3.4

110 of the NPC1-SSD or the addition of the anti-fungal drug itraconazole abolishes NPC1 activity in cell

111 ides quantitative evidence that the airborne fungal ecology of homes with known mold growth ("moldy")

112 h ("moldy") differs from the normal airborne fungal ecology of homes with no history of dampness, wat

113 ous consequences for our understanding of AM fungal ecology, from the level of the fungus, at the pla

114 We found that fungal endophyte diversity has been characterized in at

115 The influence of root fungal endophytes and arbuscular mycorrhizal fungi on pl

116 wheat leaf provides additional openings for fungal entry.

117 ly influencing the emergence of oomycete and fungal EPPs, including new introductions through anthrop

118 assembly pathway that was suppressed during fungal evolution in order to restrict assembly to octame

119 ly after emerging from pupae revealed larval fungal exposure significantly decreased overall microbia

120 how key limitations in our understanding of fungal function may obscure previously unmeasured plant-

121 Fungal functional genes involved in hydrolysis of organi

122 onate (GalOA), the first intermediate of the fungal GalA catabolic pathway, which also has interestin

123 Here, we present a combined analysis of 135 fungal genomes from 73 saprotrophic, endophytic and path

124 nctions, SM-coding regions rapidly evolve in fungal genomes.

125 saccharide biosynthetic operons and in other fungal genomes.

126 ngly induced in keratinocytes that sense the fungal glucan zymosan A.

127 erves as a developmental hormone for several fungal groups.

128 ciated with disease progression by promoting fungal growth and dissemination.

129 g mineral-associated C due to suppression of fungal growth and soil respiration.

130 d structures reported during early stages of fungal growth in nutrient-rich media, variants found her

131 tion of MPO and NADPH oxidase, and restricts fungal growth through NET release within the swarm.

132 swarming and neutrophil ability to restrict fungal growth, even during treatment with chemical inhib

133 is delayed, resulting in impaired control of fungal growth.

134 This study samples ecologically dominant fungal guilds for which there were previously no symbiot

135 tify Sfh5 as the prototype of a new class of fungal hemoproteins, and emphasize the versatility of th

136 seedlings that interact via root-associated fungal hyphae with soils beneath neighbouring adult tree

137 tchhiking motion of peroxisome organelles in fungal hyphae.

138 soria, lead the invasion of the plant by the fungal hyphae.

139 in tubular geometries such as those found in fungal hyphae.

140 d genetic polymorphisms associated with poor fungal immunity could lead to a personalized assessment

141 ation within vegetative hyphae suggests that fungal individuals have the potential to evolve within a

142 The fungal-induced change in leaf reflectance may have alter

143 VZV], blood stream infection [BSI], invasive fungal infection [IFI]) or death occurring after one mon

144 ngness-to-pay threshold (WTP) of $20 000 per fungal infection averted.

145 dial and appressorium formation, to restrict fungal infection in chilli and tomato fruits.

146 Diagnosis of fungal infection in lung parenchyma is relatively diffic

147 nvasive pulmonary aspergillosis in which the fungal infection is entirely or predominantly confined t

148 ole in plant immunity against hemibiotrophic fungal infection remains poorly understood.

149 The fungal infection significantly reduced lipase activity a

150 nsible for cryptococcosis, a deadly invasive fungal infection that represents around 220,000 cases pe

151 of augmented immunity against bacterial and fungal infection, as well as assessment of hematopoietic

152 f compounds that act specifically to prevent fungal infection.

153 es consultation for an invasive bacterial or fungal infection.

154 Appropriate diagnosis of invasive fungal infections (IFIs) is critical due to the high rat

155 nsplant recipients commonly develop invasive fungal infections (IFIs), but the most effective strateg

156 dstream infections (six [16%]), and invasive fungal infections (six [16%]).

157 Fungal infections affected 28.1% and were more common in

158 In addition, CRS with fungal and non-fungal infections also demonstrated a significant associ

159 n also be induced by bacterial, protozoal or fungal infections as well as a wide variety of toxic sub

160 or Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group criteria, and assess

161 Human fungal infections may fail to respond to contemporary an

162 roduction of substances that promote chronic fungal infections.

163 ergillosis, mucormycosis, and other invasive fungal infections.

164 the emergence and transcontinental spread of fungal infectious diseases, such as pandrug-resistant Ca

165 gross Se and Te ore levels before and after fungal interaction using X-ray fluorescence, laser ablat

166 iotics act as weapons in mediating bacterial-fungal interactions in soil.

167 ever, little is known of direct and indirect fungal interactions with Se-/Te-bearing ores.

168 tion may obscure previously unmeasured plant-fungal interactions.

169 the bacterial (16S amplicon sequencing) and fungal (internal transcribed spacer region amplicon sequ

170 derstanding of chemically mediated bacterial-fungal interrelations.

171 ome sequence of Alexander Fleming's original fungal isolate behind the discovery of penicillin, now c

172 ntifungal therapies in vivo despite in vitro fungal isolate drug susceptibility.

173 drugs, particularly against azole-resistant fungal isolates.

174 Of the 70 study subjects with fungal keratitis, 25 of 69 (36%) remained culture positi

175 many bacterial biofilms, also extends to the fungal kingdom.

176 Bacterial and fungal leaf microbiomes of the resulting near-isogenic l

177 elp discriminate between active and residual fungal lesions to support decisions for safely stopping

178 duction to chytrid fungi, an early diverging fungal lineage exhibiting characteristics found in both

179 s evolved on numerous occasions in different fungal lineages, suggesting a strong evolutionary pressu

180 todes has evolved independently in all major fungal lineages.

181 markers reflect ecological strategies of two fungal litter decomposer Gymnopus androsaceus and Chalar

182 se is tuned for converting hispidin into the fungal luciferin.

183 t C. auris and identifies critical roles for fungal mannans and mannoproteins.

184 rz1-mediated inhibition of activation of the fungal MAPK Cek1.

185 pproximate broad-scale patterns in intrinsic fungal-mediated wood decomposition rates.

186 Here we show that fungal melanin is an essential molecule required for the

187 urement with cerebrospinal fluid to diagnose fungal meningitis.

188 early structure diversity-generating step in fungal meroterpenoid biosynthetic pathways: the multibon

189 lyzed by the yet poorly understood family of fungal meroterpenoid cyclases.

190 Fungal meroterpenoids are a diverse group of hybrid natu

191 The fungal metabolite brefeldin A (BFA) and the quinoline co

192 The fungal metabolite galiellalactone (1) was, as its acetat

193 ime, the natural occurrence of non-regulated fungal metabolites in 204 maize samples harvested in Ser

194 gulate fluid influx to control absorption of fungal metabolites, which can be toxic to epithelial cel

195 ctivity of mineral nanoparticles produced by fungal-mineral interactions and contribute substantially

196 chanisms of pathogenesis is to determine how fungal morphology impacts virulence strategies.

197 epsy, brain cancer, CNS infection (viral and fungal), multiple sclerosis, cerebral ischemia, and cere

198 an seedlings that are isolated from external fungal mycelia, but these effects are observed for speci

199 atients with a T2Candida panel and mycolytic/fungal (myco/f lytic) blood culture collected simultaneo

200 Fungal N:P varied comparatively less due to simultaneous

201 t are responsible for the enormously diverse fungal natural products exist almost exclusively in fung

202 Most bacterial and fungal necromass (15) N was recovered in the mineral-ass

203 Our results showed that bacterial and fungal necromass N had similar mineralization rates, des

204 cts of elevated temperature on bacterial and fungal necromass N production, turnover, and stabilizati

205 n, we incubated (15) N-labeled bacterial and fungal necromass under optimum moisture conditions at 10

206 d the chemical and functional diversities of fungal NRPSs.

207 ws that the group containing the quinones of fungal origin, which is also the largest of the groups c

208 The structure of fungal oxyluciferin (light emitter) was proposed in 2017

209 The complexity of fungal oxyluciferin arises from diverse equilibria such

210 over, we show that chemical modifications on fungal oxyluciferin can affect the relative stability of

211 tween different conditions, we observed that fungal partners caused widespread changes in the fitness

212 We applied this approach to examine how a fungal pathogen affected the assembly processes structur

213 for potato defences against the necrotrophic fungal pathogen Alternaria solani.

214 The filamentous fungal pathogen Aspergillus fumigatus forms biofilms in

215 ing of macrophages during infection with the fungal pathogen Aspergillus fumigatus.

216 conservation is of key importance since the fungal pathogen Batrachochytrium dendrobatidis (Bd) has

217 i) are threatened with extinction due to the fungal pathogen Batrachochytrium dendrobatidis (Bd).

218 d the disease chytridiomycosis caused by the fungal pathogen Batrachochytrium dendrobatidis to show h

219 aintain phagosomal membrane integrity as the fungal pathogen Candida albicans expands.

220 e Cu-only enzyme SOD5 from the opportunistic fungal pathogen Candida albicans have revealed that the

221 In the opportunistic fungal pathogen Candida albicans, transcriptional regula

222 For the fungal pathogen Candida albicans, utilization of amino a

223 stingly, Candida tropicalis and the emerging fungal pathogen Candida auris contain a single SOD5-like

224 For host-cell interaction, the human fungal pathogen Candida glabrata harbors a large family

225 Aspergillus fumigatus is a ubiquitous fungal pathogen capable of causing multiple pulmonary di

226 Patients infected with the fungal pathogen Cryptococcus are most effectively treate

227 ulence-associated trait of the opportunistic fungal pathogen Cryptococcus neoformans is the productio

228 DNA methylation in a fungal pathogen has persisted for millions of years with

229 , which is the most important airborne human fungal pathogen in industrialized countries.

230 The fungal pathogen Sclerotinia sclerotiorum, causal agent o

231 arium graminearum, an economically important fungal pathogen that can infect both roots and heads of

232 clines of over 90% because of the introduced fungal pathogen that causes white-nose syndrome (WNS), s

233 Candida auris is an emerging fungal pathogen that exhibits resistance to multiple dru

234 Cryptococcus neoformans is an opportunistic fungal pathogen that infects ~280,000 people every year,

235 Fusarium verticillioides is a fungal pathogen that is responsible for maize ear rot an

236 Cryptococcus neoformans is a fungal pathogen that kills almost 200,000 people each ye

237 is becoming an increasingly important human fungal pathogen that should be monitored very closely.

238 pergillus fumigatus is a human opportunistic fungal pathogen whose cell wall protects it from the ext

239 is is an emerging multi-drug-resistant human fungal pathogen.

240 peutic potential of passive immunity in this fungal pathogenesis.

241 the merits and selectivity of new agents for fungal pathogens and normal cells.

242 tructurally unique NCR peptide against plant fungal pathogens and paves the way for future developmen

243 So far, 36 fungal pathogens have been authorized for introduction a

244 The emergence of new fungal pathogens makes the development of new antifungal

245 fungicidal activity against a wide range of fungal pathogens of maize, wheat and locusts, without af

246 contribute to resistance of plant and human fungal pathogens to such agents.

247 fluorescently-labeled bacterial, helminth or fungal pathogens to track and characterize the APC popul

248 loci (QTL) conferring resistance to multiple fungal pathogens were introgressed into a disease-suscep

249 t fungicidal activity against multiple plant fungal pathogens, including Botrytis cinerea and three F

250 ve been discovered for diverse bacterial and fungal pathogens, mechanisms engaged by viruses have rem

251 a auris is among the most important emerging fungal pathogens, yet mechanistic insights into its immu

252 ffectors have not been well characterized in fungal pathogens.

253 activity, and modes of action against plant fungal pathogens.

254 ome activation and PANoptosis in response to fungal pathogens.

255 ity of itraconazole against a broad range of fungal pathogens.

256 en vital in plant resistance to necrotrophic fungal pathogens.

257 s and sakuranetin was more effective against fungal pathogens.

258 ent infections, including both bacterial and fungal pathogens.

259 We tested 59 species representing most fungal phyla, and found that 53 species produce LCOs tha

260 models to examine the relationships between fungal pneumonia and FOXA2-regulated airway mucus homeos

261 and consistently elevated IRRs for viral and fungal pneumonias (up to 10.8-fold), meningitis (up to 5

262 emonstrates that the biosynthesis of complex fungal polyketides can be established and efficiently en

263 Fungal predatory behavior on nematodes has evolved indep

264 lucidated the association and involvement of fungal proteins in the formation of biogenic copper carb

265 e used within predictive frameworks of plant-fungal relationships.

266 se findings provide further understanding of fungal roles in metalloid transformations and are releva

267 es (LPMOs) are microbial enzymes secreted by fungal saprotrophs involved in carbon recycling.

268 Indeed, the term severe asthma with fungal sensitization (SAFS) has been coined.

269 at TAGAP is required for Dectin-induced anti-fungal signaling and proinflammatory cytokine production

270 Malassezia are the most abundant fungal skin inhabitant of warm-blooded animals and have

271 , the driving force and genetic mechanism of fungal SM diversification in the context of host-pathoge

272 The results showed that a great diversity of fungal species (Cordyceps, Fusarium, Harpochytrium, Emer

273 ive biomarkers for identifying bacterial and fungal species and antimicrobial resistance.

274 racnose disease is caused by the ascomycetes fungal species Colletotrichum, which is responsible for

275 metabolic diversity but higher bacterial and fungal species richness.

276 Analysis of other fungal species shows that such dual-localization is also

277 ilitates the identification of bacterial and fungal species using a sub-60-minute workflow.

278 of a 'missing' Arg side chain found in other fungal species where (i) the Cdc3 subunit is an active G

279 rys, Trichoderma, Cochlonema and two unknown fungal species) was present in emperor Yang's coffin cha

280 gene cluster in a diverse group of enigmatic fungal species.

281 hen, centromeres have been identified in >60 fungal species.

282 se disorder, and nonalcoholic controls using fungal-specific internal transcribed spacer amplicon seq

283 l glycobiomarker detection, and detection of fungal-specific volatile organic compounds will be revie

284 across eukaryotes as well as those that are fungal-specific.

285 EPR-1 is not fungal-specific; orthologs of EPR-1 are present in a div

286 cation and/or biological characterization of fungal specimens through Raman spectroscopy may require

287 udes a quiescent stage, such as bacterial or fungal spores, insect larvae, or plant seeds.

288 We found clear evidence of EM fungal suppression of C and N cycling in the Pinus-domin

289 rbon allocation tradeoffs between supporting fungal symbionts and retaining water.

290 important role in the establishment of plant-fungal symbioses.

291 mitation of the BFPP assay is the absence of fungal targets and Stenotrophomonas maltophilia, which w

292 ur study illustrates how an understanding of fungal trait variation could improve our predictive abil

293 oposes a strong connection between plant and fungal traits and the dominant form of soil nutrients.

294 ave evidence of altered gut permeability and fungal translocation.

295 We first review the current status of the fungal tree and highlight areas where additional effort

296 future challenges for fully elucidating the fungal tree of life.

297 unit Spt14 (also referred to as Gpi3) of the fungal UDP-glycosyltransferase, the first step in GPI bi

298 One of the most common fungal VOCs, 1-octen-3-ol, is a semiochemical for many a

299 In multispecies community experiments, fungal volatiles caused a shift to a Vibrio-dominated co

300 in genes in diverse species of bacterial and fungal wilt-inducing pathogens suggests that microbial e