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1 ste buds is vallate > foliate > > palate > > fungiform.
2 cate differences in morphogenetic control of fungiform and circumvallate papilla development and numb
3 e number, morphology, and spatial pattern of fungiform and circumvallate papillae and associated tast
4 in the epithelial basement membrane of early fungiform and circumvallate papillae in regions where ta
5 les, tenascin and laminin, in the developing fungiform and circumvallate papillae of fetal, perinatal
7 led to rapid loss of taste buds (TB) in both fungiform and circumvallate papillae, including disrupti
11 both wild-type and BDNF-OE mice exhibit, in fungiform buds, the same, "discrete" receptoneural patte
13 e NT4/5 gene functions in the maintenance of fungiform gustatory papillae and raises the possibility
16 ng the development and spatial patterning of fungiform papilla and targeting of taste neurons to thes
18 lopment and maintenance of taste organs, the fungiform papilla and taste bud, and surrounding lingual
20 gue shape (E13) and results in a repatterned fungiform papilla distribution that does not respect nor
22 nd morphogenetic roles for Shh in tongue and fungiform papilla formation, but also suggest that Shh f
23 ults demonstrate a prominent role for Shh in fungiform papilla induction and patterning and indicate
24 o system for studying mechanisms involved in fungiform papilla morphogenesis in patterns on the anter
27 cyclopamine, jervine, or blocking antibody, fungiform papilla numbers doubled on the dorsal tongue w
28 distinctive roles for Wnt5a in tongue size, fungiform papilla patterning and development are shown a
30 A requirement for normal Shh signaling in fungiform papilla, taste bud and filiform papilla mainte
32 ation only in taste buds, whereas 43% of the fungiform papillae also had additional labeled innervati
34 cell responses of 120 taste cells of the rat fungiform papillae and soft palate maintained within the
35 oth transgenic lines had severe reduction in fungiform papillae and taste bud number, primarily in th
36 ological and immunohistochemical analyses of fungiform papillae and taste buds were also conducted.
38 gnaling has roles in forming and maintaining fungiform papillae and taste buds, most likely via stage
40 -/-) mice the abundance of axons innervating fungiform papillae and the normal numbers of geniculate
41 These results suggest that over six months fungiform papillae are anatomically stable, playing a gr
46 cells from mouse circumvallate, foliate, and fungiform papillae but not in a variety of other cells,
47 all taste buds disappeared in more posterior fungiform papillae by 15 days posttransection, the anter
48 -expressing cells per taste bud, whereas the fungiform papillae contained 3.06 and 0.23 cells per tas
50 form papillae and formation of normal mature fungiform papillae depend on signaling through Wnt and b
54 which is the main activation pathway during fungiform papillae development; however, this effect doe
58 were sustained, TB were not restored in all fungiform papillae even with prolonged recovery for seve
66 erefore, robust, reproducible development of fungiform papillae in patterns is supported in rat tongu
68 buds, and stratified squamous epithelium of fungiform papillae in the tongue, as well as in skeletal
69 al Wnt paths in regulating tongue growth and fungiform papillae is proposed in a model, through the R
72 w it encompasses additional phenotypes (e.g. fungiform papillae number, bitterness of quinine) and em
78 an irreversibly alter number and location of fungiform papillae on anterior tongue and elicit papilla
79 petence of dorsal lingual epithelium to form fungiform papillae on both anterior and posterior oral t
80 rmates and made quantitative analyses of all fungiform papillae on the anterior tongue, the single ci
81 colocalized within papilla placodes and the fungiform papillae per se, have opposing inhibitory and
83 s chorda tympani fibers to distinguish their fungiform papillae targets from non-gustatory epithelium
84 continuity and cell turnover of a patient's fungiform papillae taste stem cell layer were disrupted
86 umbers of embryonic taste buds in developing fungiform papillae until birth are not correlated with t
92 ithelial targets of gustatory neurons (i.e., fungiform papillae) before their innervation, and BDNF o
93 ngs from isolated taste cells showed that in fungiform papillae, aldosterone increased the number of
94 three subunits in nearly all taste cells of fungiform papillae, and in about half of the taste cells
95 gue, with high levels in taste bud placodes, fungiform papillae, and mature taste cells, and low leve
96 60, there was 63% decrease in the number of fungiform papillae, and remaining papillae were smaller
97 ate neurons approach their target cells, the fungiform papillae, beginning on E13.5, at which time we
99 apillae was significantly lower than that of fungiform papillae, especially for beta and gamma subuni
100 s BMPs or noggin induce increased numbers of fungiform papillae, in a concentration-dependent manner,
101 uding reduced growth rate, reduced number of fungiform papillae, spinal abnormalities, and sensory an
102 mice, in which taste neurons innervated only fungiform papillae, taste neurons in BDNF-OE and NT4-OE
104 To explain the loss of nerve innervation to fungiform papillae, the facial nerve of developing anima
105 In mice, individual taste buds reside in fungiform papillae, which develop at mid-gestation as ep
120 the cornified tips of the filiform (but not fungiform) papillae of the dorsal tongue and in the supe
121 e of Shh, we used an in vitro model of mouse fungiform papillary development to determine the effects
130 ta are the first to characterize adult mouse fungiform taste buds and subsequent degeneration after u
131 ce to implement a slice preparation in which fungiform taste buds are in a relatively intact tissue e
136 the postnatal development and maintenance of fungiform taste buds in mice carrying a deletion of NT4/
137 There was a modest but significant loss of fungiform taste buds in Phox2b-Cre; p75(fx/fx) mice, alt
138 culate ganglion cells that innervated single fungiform taste buds were quantified in the tip- and mid
142 CT and IX-CT rats, there was regeneration of fungiform taste buds, although in both groups there were
147 e obtained whole-cell recordings from single fungiform taste cells of rat pups to examine the develop
148 ly 20% of the total outward current of mouse fungiform taste cells was composed of K(ATP) channels.
150 responses was investigated in cultured human fungiform taste papillae (HBO) cells with five arginyl d
153 regulating the number and spatial pattern of fungiform taste papillae on embryonic rat tongue, during
154 c anterograde pseudorabies virus labeling of fungiform taste papillae to infect single or small numbe
159 nilateral apical Na+ fluxes in polarized rat fungiform taste receptor cells and by chorda tympani tas