ライフサイエンスコーパス: further investigation

1 ect C. neoformans virulence in vivo warrants further investigation.

2 tients with poor tumor biology that warrants further investigation.

3 eriodontal maintenance therapy (PMT) require further investigation.

4 current knowledge that are in urgent need of further investigation.

5 standing their contribution to HLHS requires further investigation.

6 nce of malaria vectors; this, however, needs further investigation.

7 tion accuracy of this prognosis system needs further investigation.

8 es are important questions that will require further investigation.

9 nowledge gaps in the literature that require further investigation.

10 rejection with D+ raises concerns that merit further investigation.

11 which can be used as a starting position for further investigation.

12 ral C. difficile immunization events require further investigation.

13 outline various aspects of tagging that need further investigation.

14 The influence of age needs further investigation.

15 tential for vascular benefit, which warrants further investigation.

16 gies to modulate the airway ecology warrants further investigation.

17 lly bioaccumulative novel PFASs that warrant further investigation.

18 modification of surgical techniques require further investigation.

19 s of this taxonomically challenging group in further investigation.

20 l malignancies is underexplored and warrants further investigation.

21 ther health effects of these changes deserve further investigation.

22 atogram for the two struck whales and merits further investigation.

23 r type, and COVID-19 are complex and warrant further investigation.

24 disruptions due to various stressors require further investigation.

25 ent anti-mycobacterial therapy that warrants further investigation.

26 agonists and antagonists in vivo and require further investigation.

27 rs or angiotensin receptor blockers requires further investigation.

28 y steps in the virus life cycle that warrant further investigation.

29 sk to living organisms via food webs warrant further investigation.

30 ogen transmission in the region will require further investigation.

31 t on chronic lung disease pathogenesis needs further investigation.

32 nvironment during chronic infection warrants further investigation.

33 visual discomfort and indicate the need for further investigation.

34 s in RRD repair remains unknown and requires further investigation.

35 ischemic stroke independent of apoA-I needs further investigation.

36 sease in patients with dual infection merits further investigation.

37 hich alcohol is modified by smoking requires further investigation.

38 of patients after antibiotic treatment needs further investigation.

39 flare phenomenon was observed that warrants further investigation.

40 d neuroprotection in ischaemic stroke merits further investigation.

41 ation route during resuscitation that merits further investigation.

42 however is still poorly understood and needs further investigation.

43 NMDA receptor responses and recommend it for further investigation.

44 s involvement in that pathway which warrants further investigation.

45 -related and non-PE-related outcomes warrant further investigation.

46 nt azole chemosensitizing agent that warrant further investigation.

47 ng mucosal infection with HIV-1 and warrants further investigation.

48 apeutic option in this setting, and deserves further investigation.

49 disparities identified in this study warrant further investigation.

50 can improve predictive performance requires further investigation.

51 cis-regulators of known ASD risk genes, for further investigation.

52 quality and nutritional attributes requires further investigation.

53 gulates KRAS activation is unknown and needs further investigation.

54 clinical setting are questions that warrant further investigation.

55 fects of prolonged UDCA administration merit further investigation.

56 SH, while the underlying mechanisms requires further investigation.

57 nflammatory stimuli and highlights areas for further investigation.

58 ion for spinal cord stimulation and warrants further investigation.

59 into practice, highlighting areas in need of further investigation.

60 This finding supports further investigation.

61 exposure on the susceptibility of AD deserve further investigation.

62 with the "no retrofit" situation, warranting further investigation.

63 t might have clinical relevance and warrants further investigation.

64 Causal relations are unclear and need further investigation.

65 whom early cholecystectomy is safe warrants further investigation.

66 ed taxis, and highlight key areas in need of further investigation.

67 ranofin, for treatment of gonorrhea warrants further investigation.

68 ts in candidate genes for obesity warranting further investigation.

69 nknown or overlooked loci that are worthy of further investigation.

70 successful diversion must be established by further investigation.

71 umor perfusion and clinical benefit warrants further investigation.

72 a novel immunotherapy combination worthy of further investigation.

73 ce of exogenous noise on CA parameters needs further investigation.

74 These underlying mechanisms need further investigation.

75 nce among Black adults in particular warrant further investigation.

76 s, suggesting new mechanistic hypotheses for further investigation.

77 ase states over time is unknown but warrants further investigation.

78 l of proteogenomics at biopsy-scale warrants further investigation.

79 orts are all potential concerns that warrant further investigation.

80 d to soy quality and supplement matrix merit further investigation.

81 tocarcinogenesis in AHP is unknown and needs further investigation.

82 nd subsequent cardiovascular events requires further investigation.

83 Na(+)](o), with cardiac ischemia may require further investigation.

84 targeted therapeutic interventions requires further investigation.

85 on ECRS has not been elucidated and warrants further investigation.

86 ding to chronic disease disparities warrants further investigation.

87 nction with formal curricula, which warrants further investigation.

88 isks of FT should be considered and warrants further investigation.

89 s can suggest potential driver mutations for further investigation.

90 wly identified bacterial taxa in RA warrants further investigations.

91 Upon further investigation a rare cause of pseudoachalasia du

92 this disease, which highlights the need for further investigation about the pathophysiology of this

93 future mantle flow simulations, and call for further investigations about the deformation mechanisms

94 But this needs further investigation among cognitively normal older adu

95 Thus, the need for further investigation and development of effective thera

96 DCN may serve as a target for further investigation and modulation of anti-angiogenic

97 Further investigation and stronger national guidelines a

98 This review has important implications for further investigations and applications of kenaf in food

99 These approaches need further investigation, and we propose a phased stepwise

100 Further investigations are needed to elucidate the exact

101 Further investigations are needed to elucidate the role

102 Further investigations are needed to identify which pati

103 to treat pancreatic-enteric anastomoses, but further investigations are required for optimization in

104 Further investigations are required to assess the effect

105 Further investigations are required to maximize the iden

106 d to treat human cryptosporidiosis; however, further investigations are required.

107 Further investigations are warranted into disease-specif

108 Further investigations are warranted to elucidate source

109 The inhibition of TLR4 signaling warrants further investigation as a candidate strategy for fetal

110 or refractory non-Hodgkin lymphoma warrants further investigation as a chemotherapy-free option in t

111 Intranasal IL-4 treatment warrants further investigation as a clinically feasible therapy f

112 t treatment, may be a promising strategy for further investigation as a future treatment.

113 entions targeting the gut microbiota warrant further investigation as a novel renoprotective therapy

114 rties of hydroxynorketamine that warrant its further investigation as a possible therapeutic in patho

115 two models of increased dopamine, warranting further investigation as a potential therapeutic target

116 pounds that are intriguing in terms of their further investigation as inhibitors of MDM2-p53 interact

117 gest that RAP, and thus g-gradient, warrants further investigation as it may support use as a holisti

118 uggest that 3,5-bis(styryl)pyrazoles warrant further investigation as lead compounds for the treatmen

119 findings suggest aryl-alkyl-lysines warrant further investigation as novel agents to treat CDI.

120 hosphonate ProPAgens as ideal candidates for further investigation as novel cancer immunotherapeutic

121 nical performance of the DCNN model warrants further investigation as part of randomised clinical tri

122 e monophosphate signaling enhancers warrants further investigation as therapy for BA.

123 h death among hospitalized patients warrants further investigation, as do associations between certai

124 mprovement are currently unknown and require further investigation, as reversing the dysregulation of

125 ependent subtypes in the prodrome of PD need further investigation based on prospective clinical and

126 r the pooled cohort equations model warrants further investigation before clinical implementation.

127 ive variation in their glycans, meaning that further investigations can shed light not only on the sp

128 Further investigation demonstrated activation of apoptot

129 Further investigation demonstrated the importance of pro

130 orm-specific manner, providing the basis for further investigations elucidating the role of dedicated

131 tions targeting this system may be worthy of further investigation for PTSD treatment.

132 stroke include long-term cardiac monitoring, further investigation for structural cardiac disease and

133 tic value, while other fitness genes warrant further investigation for their potential as therapeutic

134 The regimen would be considered worthy of further investigation if 26 or more of 37 patients were

135 liminary results are encouraging and warrant further investigation in a large multicenter phase 3 tri

136 meaningful proof-of-concept data now warrant further investigation in a larger patient cohort.

137 Further investigation in a mouse model overexpressing ex

138 Further investigation in a pivotal phase 3 trial is unde

139 omarker of oxidative damage by HOBr warrants further investigation in clinical conditions linked to h

140 The data support further investigation in clinical model systems of the p

141 its consequences for child development need further investigation in future larger studies.

142 These findings warrant further investigation in HIV preexposure prophylaxis stu

143 od pressure in hypertensive rats and justify further investigation in large animals and eventually in

144 ND pathogenesis remains unclear and warrants further investigation in larger, longitudinal cohorts.IM

145 ion of capivasertib and fulvestrant warrants further investigation in phase 3 trials.

146 term safety of acalabrutinib, justifying its further investigation in previously untreated and treate

147 nversely associated with PASP which warrants further investigation in prospective studies.

148 For such patients, further investigation in regard to etiology of the visua

149 Further investigation in relevant experimental models wi

150 This combination warrants further investigation in this setting.

151 Further investigations in an earlier infant schedule sho

152 Our findings provide new leads for further investigations in cohort studies and animal mode

153 ies of beer, which would provide a basis for further investigations in reformulation of 0% ABV drinks

154 al horn; and (3) this work opens the door to further investigations in vivo of spinal cord dendritic

155 h IS upon hospital arrival, thus encouraging further investigation, including multicenter studies.

156 These findings will guide further investigation into cellular and circuit mechanis

157 Findings also support further investigation into Cu as both beneficial and tox

158 Further investigation into E66S CCL5-Evasin-4 complex fo

159 Further investigation into factors underlying sex-based

160 umors after immune priming therapy, warrants further investigation into its utility for patient selec

161 g granuloma-associated fibrosis and warrants further investigation into myeloid cells as drivers of f

162 rature for this family of fishes and prompts further investigation into other novel reproductive mode

163 uteroplacental perfusion and thereby justify further investigation into PPARgamma as a therapeutic ta

164 ical period of brain development could guide further investigation into sex-dependent mechanisms and

165 a PARP-1-targeted Auger emitter, calling for further investigation into targeted Auger therapy.

166 These findings should form the basis for further investigation into temporal variations in self-h

167 Further investigation into the function of XP revealed p

168 CaP progression and provide a foundation for further investigation into the functional role of nucleo

169 ism of therapeutic interference, and prompts further investigation into the interaction between CAR T

170 Results from this study warrant further investigation into the mechanisms underlying dec

171 d by acute nicotine deprivation and call for further investigation into the potential utility of aden

172 lements of NEAT1 and provide a framework for further investigation into the role of G-quadruplexes in

173 These findings provide support for further investigation into the utility of pharmacologica

174 Further investigation into these cases with additional g

175 Further investigation into these epigenetic mechanisms w

176 sation of the SkT state, opening the door to further investigation into this unexplored dimension of

177 characteristics of TF viruses thus prompting further investigation into virus-host interaction occurr

178 re provides a biological platform upon which further investigations into 3D developmental processes c

179 These studies have formed the basis of further investigations into the important role that the

180 fluence of the stimulus cue on the ETO bias, further investigations into the mechanisms underlying th

181 These results should stimulate further investigations into the precise mechanisms under

182 m functioning in the disorder, and encourage further investigations into the underlying mechanisms, a

183 Further investigation is necessary to identify the under

184 mitation to its practical implementation and further investigation is necessary.

185 Further investigation is needed to better resolve enviro

186 e for an in-person training workshop, though further investigation is needed to determine why only a

187 Further investigation is required to optimize model perf

188 of nonbiologic systemic therapies; however, further investigation is warranted on account of potenti

189 Further investigation is warranted to delineate factors

190 Further investigation is warranted to determine if clini

191 Further investigation is warranted to determine if targe

192 Further investigation is warranted to understand the dri

193 bstructive sleep apnea and CKD among adults, further investigation is warranted.

194 Further investigation may help to improve anticipatory g

195 These results support further investigation of 14a as a potential treatment fo

196 Further investigation of ASFVsRNA2 detected it in lympho

197 These findings encourage further investigation of both the potential application

198 Further investigation of cell contact dynamics as guidan

199 e precluded further development and prompted further investigation of close analogues.

200 e precluded further development and prompted further investigation of close analogues.

201 Our results establish a rationale for further investigation of combined BET and CDK4/6 inhibit

202 g women at short-term risk of breast cancer, further investigation of common loci associated with mam

203 Our study warrants further investigation of CRCNet by prospective clinical

204 In this study, we found that further investigation of DNA/protein regimens is warrant

205 This feasibility study supports further investigation of fast high-resolution MRSI in ac

206 The results call for further investigation of FeNOs in normal and complicated

207 Further investigation of gemogenovatucel-T in patients s

208 These results support the need for further investigation of genetic risk factors that modul

209 to other modules in GlycanStructure.ORG for further investigation of glycan-binding sites and glycan

210 The model also provides a tool for further investigation of heart failure drug therapies.

211 ighly valuable natural product, facilitating further investigation of hemiasterlin and its analogues

212 sults of this study provide a foundation for further investigation of heparin's interactions with IL-

213 Further investigation of how such factors contribute to

214 sis of a randomized controlled trial support further investigation of IL-1beta inhibition for treatme

215 Further investigation of immunotherapy in patients with

216 ukin-18 response are potential subgroups for further investigation of inhaled IFN-beta1a.

217 ese findings provide a valuable resource for further investigation of lipid metabolism in liver of ch

218 Altogether, this work provides resources for further investigation of mechanisms involved in gastroin

219 These results support further investigation of mGluR2/3 and other glutamate-ta

220 tlases, we provide an extensive resource for further investigation of mouse neuronal cell types.

221 on occurred early, which suggests a need for further investigation of optimal iTBS time course and du

222 ive immune regulation in tumours and support further investigation of phagocytosis modulation as a st

223 Further investigation of precisely how the SSC improves

224 Further investigation of PSMD1 revealed that an interact

225 ro These findings provide information to aid further investigation of SARS-CoV-2 infection mechanisms

226 Further investigation of specific and general defenses w

227 and provide mechanistic insights supporting further investigation of specific IBD drugs in the treat

228 reactive TRAJ24(+) cells opens an avenue for further investigation of the autoimmune contribution to

229 This conundrum has spurred further investigation of the cell type-specific effects

230 Our findings may open new doors for further investigation of the distinct biology of TNBC vs

231 Further investigation of the European synthesis results

232 l role in basal body biogenesis in T. brucei Further investigation of the functional interplay among

233 on SARS-CoV-2 sequences in vitro and in vivo Further investigation of the mechanism of generating the

234 ce of the ST gene family and will enable the further investigation of the molecular mechanism of suga

235 Further investigation of the myeloid network indicated a

236 Further investigation of the nature of this interference

237 als using NMR spectroscopy but suggests that further investigation of the rate and position of enrich

238 ethods and approaches form a solid basis for further investigation of the role of HLA-G+ EVT in the d

239 Our work opens new avenues for further investigation of the role of this functionally m

240 Further investigation of the structure-activity relation

241 ely consistent compared with other RCCs, but further investigation of the tumour-immune cell microenv

242 unable l or c content was realized, allowing further investigation of thermal and viscoelastic materi

243 Further investigation of these developmental pathways co

244 Further investigation of these observations is warranted

245 Early efficacy data support further investigation of this approach.

246 diated MMP activation and open the field for further investigation of this important signaling pathwa

247 Further investigation of this score with respect to down

248 These results support further investigation of trastuzumab deruxtecan for HER2

249 reement with previous literature and warrant further investigation of using this system to measure ex

250 Further investigation of USP20 demonstrated its function

251 d-trap malaria vaccines and will greatly aid further investigations of cellular antimalarial immunity

252 These results support further investigations of free PEG prophylaxis as a pote

253 refrontal and cingulate cortices, warranting further investigations of GBC as a putative imaging mark

254 d underlying datasets provide a resource for further investigations of human B cell identity and func

255 However, further investigations of OT functions, especially over

256 provide insights into nosology and encourage further investigations of shared and unique pathophysiol

257 ce of monocot terpenoid metabolism to enable further investigations of terpenoid-mediated stress resi

258 exposure to ST enterotoxin and suggests that further investigations of the application of these mecha

259 These data demonstrate the urgent need for further investigations of the postharvest ripening proce

260 Further investigations of unconventional secretory pathw

261 Further investigation on aerosol WSOM could help to cons

262 Further investigation on the chronic impact and risk cal

263 Further investigations on different stages of OA would b

264 ymer, so far not considered, and encouraging further investigations on its potential application in b

265 o guide individual decisions on the need for further investigation or referral.

266 Therefore, further investigation regarding the impact of CyanoHABs

267 Further investigation revealed evidence of alternative s

268 Further investigation revealed that Dicer was decreased

269 Further investigation revealed that vessel elements ceas

270 g fab2 and aad5 could never be obtained, and further investigations revealed that the double mutation

271 Further investigation reveals that OTUD5 depletion leads

272 Further investigation showed that the dysregulation of B

273 Further investigation showed that the main path of 50S a

274 Further investigations showed that cytoplasmic, but not

275 Further investigation shows that the gradient-tailored L

276 peutic treatment in AGC1 deficiency deserves further investigation.SIGNIFICANCE STATEMENT Aralar defi

277 a genetic level, brings a pressing need for further investigation so protective strategies can be im

278 Further investigation suggested that liposome disruption

279 immunobiology of B cells and areas requiring further investigation that might lead to new therapies o

280 Future studies are warranted for further investigations that should impact the need for p

281 ific immune cells during development require further investigation, the system as a whole displays ma

282 On further investigation, these fluorophores turned out to

283 These trends during the COVID-19 era warrant further investigation to address unmet needs, plan for a

284 and highlights key knowledge gaps warranting further investigation to attenuate patient risk.

285 ncy BMI on childhood obesity, which warrants further investigation to establish the cause-and-effect

286 ture and extent of these disparities require further investigation to identify strategies for expandi

287 s on two reaction intermediates and requires further investigation to really understand the mode of a

288 bacter species, and may serve as a model for further investigations to elucidate the host-microbe int

289 s blunted in MELAS cells, was surprising and further investigation uncovered that under conditions of

290 Based on trends in the models, further investigation was conducted using Piezo1 gain-of

291 Further investigations will be required to better unders

292 n altered unconventional T cell biology, and further investigations will be required to precisely ass

293 These early findings warrant further investigation with additional records of combine

294 Although the role of domain walls requires further investigation with local probes, the methodology

295 The UH2 regimen warrants further investigation with modifications to reduce toxic

296 en a small effect on CHD cannot be excluded, further investigation with stronger genetic predictors i

297 We also discuss potential areas of further investigation with the aim to optimize current l

298 A further investigation with two model compounds reconfirm

299 onses against resistant cancers and warrants further investigation, with the potential to broaden ML

300 es to reduce the number of compounds needing further investigation, without relying on a suspect list