ライフサイエンスコーパス: gamma subunit

1 ial myocytes express a functional BK channel gamma subunit.

2 edox modulation of a disulfide bridge on its gamma subunit.

3 uman ENaC, an effect mediated in part by the gamma subunit.

4 RNA specific to the endogenous translocating gamma subunit.

5 d by our data showing mislocalization of the gamma subunit.

6 calcium channels were also associated with a gamma subunit.

7 n-dependent cleavage site (RKRK(186)) in the gamma subunit.

8 nd at a single extracellular site within the gamma subunit.

9 a locus distinct from its active site on the gamma subunit.

10 lpha subunit and at a single site within the gamma subunit.

11 nd delta' functionally influence an adjacent gamma subunit.

12 ic protein consisting of an alpha, beta, and gamma subunit.

13 (Lys-189) in the extracellular domain of the gamma-subunit.

14 phabeta-dimers creates torque on its central gamma-subunit.

15 e-interacting beta-subunit, and a regulatory gamma-subunit.

16 nd product release, inducing a torque on the gamma-subunit.

17 transiently stored as elastic energy in the gamma-subunit.

18 nd M3 transmembrane helices in the alpha and gamma subunits.

19 ric G-protein consisting of alpha, beta, and gamma subunits.

20 hate in the complete absence of the beta and gamma subunits.

21 vage of the extracellular loops of alpha and gamma subunits.

22 f the extracellular domains of the alpha and gamma subunits.

23 the requirement for the regulatory beta and gamma subunits.

24 residue found at the homologous position in gamma subunits.

25 relative protein content of alpha, beta, and gamma subunits.

26 explored the function of the alpha/beta and gamma subunits.

27 cluding Rho, Rap1, Rac, Cdc42, and G-protein gamma subunits.

28 oocytes injected with ENaC-alpha, beta, and gamma subunits.

29 lso contain auxiliary alpha2delta, beta, and gamma subunits.

30 f the extracellular domains of the alpha and gamma subunits.

31 dimer (Palphabeta) that binds two inhibitory gamma subunits.

32 the extracellular domains of the alpha- and gamma-subunits.

33 pe cells and in cells lacking beta- and Snf4/gamma-subunits.

34 inhibited by the cone- and rod-specific PDE6 gamma-subunits.

35 es internalization of the alpha-, beta-, and gamma-subunits.

36 KC consensus site on the alpha- or beta- and gamma-subunits.

37 rted a role for the heterotrimeric G protein gamma subunit 1 (Ggamma1) in mediating cardial-pericardi

38 ed of two alpha-subunits (68.8 kD each), one gamma-subunit (22.5 kD), and one delta-subunit (11.9 kD)

39 .1 kD each), one beta-subunit (56.0 kD), one gamma-subunit (24.8 kD), and one delta-subunit (13.9 kD)

40 lent residues in the nACh receptor delta and gamma subunits) abolished and severely attenuated functi

41 induction of "fetal" acetylcholine receptor gamma subunit (AChRgamma), reduction of "adult" AChRepsi

42 The conservation of primary structures of gamma-subunits across mammalian species suggests that th

43 ce expression and normal levels of alpha and gamma subunit-activating cleavage.

44 on of a role of the heterotrimeric G-protein gamma subunit, AGG3, in cold tolerance, as newly predict

45 rylation in mice and fibroblasts lacking the gamma subunit along with kinetic studies of recombinant

46 rin cleavage and the inhibitory tract in the gamma subunit (alphabetagammaR143A,DeltaE144-K186) showe

47 units regulate the activity of the catalytic gamma subunit and account for 81% of PhK's mass.

48 ontain an endogenous translocating G protein gamma subunit and exhibit receptor-induced Golgi fragmen

49 ndocytosis requires an activating FcgammaR's gamma subunit and involves astrocytic membrane loss of a

50 es of gold nanorods attached to the rotating gamma subunit and/or by increasing the viscosity of the

51 reonine phosphorylation of the ENaC beta and gamma subunits and abolished by inhibitors of (a) mitoge

52 ing of AMPK, HSF1 impairs AMP binding to the gamma subunits and enhances the PP2A-mediated de-phospho

53 t, contains three G alpha, one G beta, one G gamma subunits and phosducin-like protein BDM-1 that hav

54 Additionally, crystallin-gamma subunits and serotonin-related genes were highly e

55 haracterized, the identities of its beta and gamma subunits and their function in olfactory signal tr

56 between the amino acid sequences of various gamma subunits and their translocation properties.

57 ta reveal the specific coupling between ENaC gamma-subunit and claudin-8 expression.

58 ing for the observed torque generated on the gamma-subunit and its change due to mutation of this uni

59 ed of a single copy of an alpha-, beta-, and gamma-subunit and plays an essential role in water and s

60 C is enhanced by proteolytic cleavage of the gamma-subunit and putative release of a 43-amino acid in

61 rrangements disrupt interactions between the gamma-subunit and the C-terminal domain of the alpha(E)-

62 rved an asymmetric binding of the inhibitory gamma-subunit and the noncatalytic cGMP to the GAFa doma

63 termined by a small unique region within the gamma-subunit and this region contains two cysteine resi

64 omplex is composed of two alpha-, beta-, and gamma-subunits and represents the key enzyme for the bio

65 ongation factor (eEF) 1B (alpha-, beta-, and gamma-subunits) and eukaryotic translation initiation fa

66 ciferase, IkappaB beta/gamma kinase (IKKbeta/gamma) subunits, and PAD2.

67 the extracellular domains of its alpha- and gamma-subunits, and it was recently reported that ENaC a

68 zed threonine phosphorylation of the channel gamma subunit: and (c) characterize a common scientific

69 that the two cytoplasmic Cys residues in the gamma subunit are palmitoylated.

70 oteolytic processing events of the alpha and gamma subunits are associated with channel activation.

71 eric G proteins composed of alpha, beta, and gamma subunits are central signal transducers mediating

72 ments in reconstituted gamma-KO cells, whose gamma subunits are linked by disulfide bonds, as well as

73 he furin and prostasin cleavage sites in the gamma subunit, are inhibitory domains.

74 ric G proteins, composed of alpha, beta, and gamma subunits, are activated by exchange of GDP for GTP

75 ins), which are composed of alpha, beta, and gamma subunits, are versatile, guanine nucleotide-depend

76 ed upon siRNA-mediated knockdown of the AP-1 gamma subunit, as predicted for the common AP-1-dependen

77 in association with inducing cleavage of the gamma subunit at gammaLys194, a site distal to the furin

78 Cleavage of the alpha and gamma subunits at multiple sites activates the channel t

79 proteins in enriched fractions, ATP-synthase gamma-subunit (AtpC) and Rubisco activase (RCA) were ide

80 rimeric complex composed of alpha, beta, and gamma subunits, belongs to the ENaC/degenerin family of

81 ubunit, suggesting a role for this region in gamma subunit binding.

82 6-phosphate receptor homology domain of the gamma subunit binds and presents the high mannose glycan

83 The G-protein G(beta)gamma subunit blockers suramin (8,8'-[carbonylbis[imino-

84 ha subunits themselves and between alpha and gamma subunits, both of which were decreased in CRT hear

85 Dopamine activation required beta and gamma subunits but not alpha subunits ((Z)beta3gamma2 EC

86 Coexpression of the gamma-subunit (but not the beta-subunit) is essential fo

87 cting as a solid "pushrod" to push the rotor gamma subunit, but the short helix in F(1)(1/2)s would f

88 Mitochondrial levels of the gamma-subunit, but not the alpha- and beta-subunits, wer

89 ound that modifying the Arabidopsis thaliana gamma subunit by mutating three highly conserved acidic

90 alpha and beta are encoded by two genes, the gamma subunit by three genes, all of which are expressed

91 lcium/calmodulin-dependent protein kinase II gamma subunit (CaMKIIgamma), a component of the NMDA rec

92 Introduction of this region within the yeast gamma-subunit causes a defect in oxidative phosphorylati

93 none functional regulation of BK channels by gamma-subunits: channels either exhibit a full gating sh

94 duction of a unique 70-kDa carboxyl-terminal gamma subunit cleavage fragment.

95 nto the pore of the ring, reminiscent of the gamma subunit complexed to alpha(3)beta(3) of F(1)-ATPas

96 s alphabetagamma complexes, whose regulatory gamma subunit confers energy sensor function by binding

97 tracellular finger domains of ENaC alpha and gamma subunits contain allosteric regulatory modules.

98 hECN GABAARs are predominantly gamma subunit-containing as assessed by the sensitivity

99 compares with an IC50 of 85 muM for synaptic gamma subunit-containing GABAARs (gamma-GABAARs).

100 These data indicate that the gamma-subunit controls the expression level of the entir

101 alpha decreased levels of alpha-, beta-, and gamma-subunits, decreased F0F1-ATPase activity, and hind

102 nucleotides, and the position of the central gamma subunit determines which site has high, medium, or

103 The gamma subunits differentially modulate Ca(2+) channel fu

104 x-sensitive labeling studies showed that the gamma subunit disulfide/sulfhydryl couple in the modifie

105 , we show that elimination of the transducin gamma-subunit drastically reduces signal amplification i

106 h HdrABC and dissimilatory sulfite reductase gamma subunit (DsrC) to perform novel electron transfer

107 However, furin cleaves the gamma subunit ectodomain only once.

108 of a 43-amino acid inhibitory tract from the gamma-subunit ectodomain.

109 We infer that the auxiliary gamma subunit effectively interferes with mallotoxin on

110 ive up-regulation of several AMPK-alpha and -gamma subunit-encoding genes in GH-transgenic fish achie

111 toward a subset of the acid hydrolases, the gamma subunit facilitates the addition of the second Glc

112 The eight members of the calcium channel gamma subunit family are integral membrane proteins that

113 xpression of both FcgammaRIIa and the common gamma subunit following Pam2CSK4 treatment.

114 at close to wild-type levels but require the gamma subunit for optimal phosphorylation of the rest of

115 catalytic F(1) head rotates with the central gamma-subunit for the first part of each ATP-generating

116 Loss of the gamma subunit from wrapping glia resulted in a disruptio

117 Recombinant GST ENaC alpha, beta, and gamma subunit fusion proteins were expressed in Escheric

118 cathepsin B but not the full-length beta or gamma subunit fusion proteins.

119 ric G proteins, composed of alpha, beta, and gamma subunits (Galphabetagamma).

120 uctured RGD-lacking C-terminal region of the gamma subunit (gammaC peptide).

121 re gated by direct binding of G protein beta-gamma subunits (Gbetagamma), signaling lipids, and intra

122 r investigate the risk susceptibility by the gamma subunit gene family to SCZ, we conducted a large-s

123 e, we show that genetic deletion of the AChR gamma-subunit gene in mice leads to an absence of pre-pa

124 al association of the five known beta and 12 gamma subunit genes.

125 ected in degenerating rods of the transducin gamma-subunit (Ggamma1) knockout mouse.

126 However, the function of the small beta- and gamma-subunits has remained unclear.

127 Insertions in the alpha- and gamma-subunits have little effect on GABA or SR-95531 ac

128 odulator (NEMO; also known as IkappaB kinase gamma subunit [IKKgamma]).

129 revealed phosphorylation of Ser(146) on the gamma subunit in response to wtPKC-alpha overexpression.

130 results underscore the critical role of the gamma subunit in this process.

131 and efficiently associated with the beta and gamma subunits in the plasma membrane.

132 pe is not due to redundant roles for the two gamma subunits in the same signaling pathway but rather

133 the relationship between mallotoxin and the gamma subunits in their BK channel-activating effects in

134 We have here addressed the role of the Snf4 (gamma) subunit in regulating SNF1 protein kinase in resp

135 ouse models containing either isoform of the gamma-subunit in the heart.

136 In response to torque-driven rotation of the gamma-subunit in the hydrolysis direction, the nucleotid

137 echanical energy and torque (rotation of the gamma-subunit) in F1-ATPase is very challenging.

138 hat removal of the inhibitory tract from the gamma subunit, in the absence of alpha subunit cleavage,

139 g to multiple extracellular sites within the gamma-subunit, including (i) a high-affinity stimulatory

140 e epithelial sodium channel (ENaC) alpha and gamma subunits increases the channel's open probability

141 A second distal cleavage in the gamma subunit induced by other proteases, such as prosta

142 the highly conserved acidic residues in the gamma subunit influence thiol redox potential.

143 When channels lacked the alpha and gamma subunit inhibitory tracts, alpha subunit cleavage

144 nnel as a result of release of the alpha and gamma subunit inhibitory tracts, respectively.

145 hat can consume ATP to drive rotation of the gamma-subunit inside the ring of three alphabeta-subunit

146 at or near one ACh binding site at the alpha/gamma subunit interface.

147 rresponding to the fragment cleaved from the gamma subunit is a reversible inhibitor of endogenous EN

148 cytes the AP-1 beta subunit is lost, and the gamma subunit is greatly reduced, demonstrating destabil

149 interaction site near the N terminus of the gamma subunit is important for recruitment, but not acti

150 aken together, we conclude that although the gamma subunit is not required for the binding of GABA or

151 Activity of the catalytic gamma subunit is regulated by allosteric activators targ

152 6-phosphate receptor homology domain of the gamma subunit is required for optimal phosphorylation.

153 The C8 gamma subunit is unrelated and belongs to the lipocalin

154 rmore, we observe that communication between gamma subunits is necessary for both regulatory roles.

155 These results demonstrate that the gamma-subunit is required for the formation of pre-patte

156 channel (ENaC) formed by alpha-, beta-, and gamma-subunits is a shear force (SF) sensor and a member

157 We tested the importance of each regulatory gamma subunit isoform to metformin action in this curren

158 Conditional kidney tubule-specific ENaC gamma-subunit knockout mice displayed decreased claudin-

159 t homologous sites within either the beta or gamma subunit knuckle domain resulted in little or no ch

160 In contrast, deletion of either the beta or gamma subunit knuckle domain within the alphabetagamma t

161 other at the interface between the alpha and gamma subunits (labeling of alphaM2-10 and gammaMet-299)

162 ociation of the complex; similarly, a mutant gamma-subunit lacking the [4Fe-4S] cluster is unable to

163 We demonstrate that loss of the laminin gamma subunit (LanB2) in the peripheral glia of Drosophi

164 ATPase, 2) interacts with alpha-, beta-, and gamma-subunits leading to increases in their phosphoryla

165 demonstrate that the knock-out of transducin gamma-subunit leads to a major downregulation of both al

166 cells by reducing mRNA expression of the BK gamma subunit leucine-rich repeat-containing protein 26

167 rexpressing wtPKC-alpha blocked decreases in gamma-subunit levels, maintained F0F1-ATPase activity, a

168 that the C-terminus of the photosynthetic F1 gamma subunit, like its mitochondrial counterpart, forms

169 cobacterial, termed GaMF1, that targets this gamma subunit loop.

170 ine-rich-repeat-containing (LRRC) regulatory gamma subunits, LRRC26 and LRRC52, to BK channel functio

171 To study the importance of the gamma subunit M2-M3 linker, we examined the macroscopic

172 ng enhanced green fluorescent protein in the gamma-subunit M3-M4 loop, which confirmed our nAChR beta

173 C26 (leucine rich repeat containing 26), the gamma subunit mandatory for BK function in the airways.

174 i clamp loader that exists in space as three gamma-subunits (motor) flanked by the delta' (stator) an

175 Therefore, neither the gamma-subunit nor the regulatory ATP bound to the epsilo

176 technique to identify the NADH dehydrogenase gamma subunit (nuoG) primer set that is sensitive and sp

177 2 in the alpha1 subunit of GlyRs and in the gamma subunit of alpha1beta2gamma2GABA(A)Rs and measured

178 The gamma subunit of AMPK binds AMP and ATP, and mutations t

179 te ligands bound to one or more sites in the gamma subunit of AMPK promote the formation of an active

180 nteraction between ERManI and gamma-COP, the gamma subunit of coat protein complex I (COPI) that is r

181 utations in the EIF2S3 gene that encodes the gamma subunit of eIF2.

182 events injury-induced decreases in levels of gamma subunit of F0F1-ATPase, 2) interacts with alpha-,

183 c mice (TG-CRP) with either mice lacking the gamma subunit of FcgammaRI (FcRgamma(-/-)) or FcgammaRII

184 Similarly, replacing Loop 2 of the gamma subunit of GABA(A)Rs with deltaL2 shifted the etha

185 s bind at the interface between an alpha and gamma subunit of GABA(A)Rs, preferentially enhancing syn

186 tations in the GNPTG gene, which encodes the gamma subunit of GNPT, in affected subjects of Asian and

187 ls were determined by ELISA specific for the gamma subunit of NSE.

188 cterize the loss of SNF4Agamma, encoding the gamma subunit of the AMP Kinase complex.

189 s possesses two homologues of the regulatory gamma subunit of the ATP synthase, encoded by the ATPC1

190 PII also bind to the yeast orthologue of the gamma subunit of the COPI coat complex (Sec21p), a known

191 ation of key functional features seen in the gamma subunit of the eukaryotic AMP-activated protein ki

192 he N terminus of zeta blocks rotation of the gamma subunit of the F1-ATPase of P. denitrificans by a

193 Mutations in EIF2S3, encoding the gamma subunit of the heterotrimeric eukaryotic translati

194 pathways by inducing the degradation of the gamma subunit of the inhibitor of kappaB kinase complex

195 The gamma subunit of the rotor, which plays a central role i

196 Evidence suggests the alpha and gamma subunits of ENaC are cleaved during assembly befor

197 1, ASIC3, TRPV4, TRPA1, the alpha, beta, and gamma subunits of ENaC, and the two pore K+ channels (TR

198 suggest that palmitoylation of the beta and gamma subunits of ENaCs enhances interactions of their r

199 phosphorylation events in alpha4, beta, and gamma subunits of GABA(A)Rs govern their function and tr

200 l modification of Met to Asp was reported in gamma subunits of human fetal Hb Toms River (gamma67(E11

201 auxiliary metabolic genes for the alpha and gamma subunits of reverse dissimilatory sulfite reductas

202 ctional analyses reveal that the B56gamma (B'gamma) subunit of an essential host enzyme, protein phos

203 hat Aly1 and Aly2 interact directly with the gamma-subunit of AP-1, Apl4.

204 This activation was mapped to the gamma-subunit of ENaC.

205 The gamma-subunit of fetal AChRs is indispensable for the pr

206 family of small GTPases, nuclear lamins, the gamma-subunit of heterotrimeric GTPases, and several pro

207 total ProGRP, as well as the alpha- and the gamma-subunit of NSE isoenzymes.

208 ypertension due to mutations in the beta- or gamma-subunit of the epithelial sodium channel (ENaC).

209 The recombinant mAb 131 is specific for the gamma-subunit of the fetal AChR to which it bound with s

210 e observed where certain mutations in the F1-gamma-subunit of the two-sector F1Fo-ATP synthase allow

211 Conversely, the alpha- and gamma-subunits of AMPK are O-GlcNAcylated, O-GlcNAcylati

212 dle syndrome, a mutation of the beta- and/or gamma-subunits of ENaC produces an activated ion channel

213 creased protein levels of alpha-, beta-, and gamma-subunits of F0F1-ATPase in RPTC.

214 o-immunoprecipitated with alpha-, beta-, and gamma-subunits of F0F1-ATPase.

215 mplex (ODC) also antibodies to the beta- and gamma-subunits of F1F0-ATPase (anti-beta, anti-gamma) oc

216 Antibodies to the beta- and gamma-subunits of F1F0-ATPase occur in anti-M2 positive

217 mily of transmembrane proteins that includes gamma-subunits of voltage-gated calcium channels.

218 Ca(2+) channel gamma subunits, of which there are 8 isoforms, consist o

219 nation of the effect of various parts of the gamma-subunit on free energy surfaces of F1-ATPase.

220 own to induce the 40 degrees rotation of the gamma-subunit only when the betaE subunit is empty, wher

221 Furthermore, gamma subunit palmitoylation had a dominant role over be

222 ndividual or multiple subunits revealed that gamma subunit palmitoylation has a dominant role over be

223 ENaC activation by DHHCs was lost when gamma subunit palmitoylation sites were mutated, whereas

224 sducin beta-subunit without its constitutive gamma-subunit partner sufficiently stresses the cellular

225 retinal phosphodiesterase (PDE6) inhibitory gamma-subunit (PDEgamma) plays a central role in vertebr

226 clic GMP phosphodiesterase (PDE6) inhibitory gamma-subunit (PDEgamma) stimulates GTPase activity of t

227 for the C-terminal region of the inhibitory gamma subunit (Pgamma), known to directly inhibit PDE6 c

228 How the PDE6 inhibitory gamma-subunit (Pgamma) interacts with the catalytic subu

229 ction of phosphodiesterase-6 (PDE6) with its gamma-subunit (Pgamma) is pivotal in vertebrate phototra

230 hosphodiesterase (PDE6), is regulated by its gamma-subunit (Pgamma), whose inhibitory constraint is r

231 DE6 activity is suppressed by its inhibitory gamma-subunit (Pgamma).

232 upon binding of cGMP and the PDE6 inhibitory gamma-subunit (Pgamma).

233 nhibition by the cone- and rod-specific PDE6 gamma-subunits (Pgamma) were comparable.

234 photoreceptor cells contains two inhibitory gamma-subunits (Pgamma) which bind to the catalytic core

235 ytic heterodimer but also for its regulatory gamma-subunits (Pgamma) whose inhibitory action is relea

236 sed in the dark by binding of two inhibitory gamma-subunits (Pgamma).

237 tructure prediction of the N terminus of the gamma subunit places gammaCys-33 within an alpha-helix a

238 cterium-specific loop of the enzyme's rotary gamma subunit plays a role in the coupling of ATP synthe

239 such as Ras, most Rho GTPases, and G protein gamma subunits, plays an essential role in determining t

240 Simulations reveal that, in response to gamma-subunit position, the active site conformation is

241 s peroxisome proliferator-activated receptor gamma subunit (PPAR-gamma), the master activator of adip

242 e valine-modified chloroplastic ATP synthase gamma-subunit precursor elicited significantly stronger

243 nic PKA activity and levels of PKA catalytic gamma subunit protein were significantly lower in granul

244 rms and regulators, G-protein alpha-and beta,gamma-subunits, protein kinase A subtypes and the phosph

245 n of fragments of chloroplastic ATP synthase gamma-subunit proteins, termed inceptin-related peptides

246 meric G proteins composed of alpha, beta and gamma subunits regulate a number of fundamental processe

247 E) 6 complex, made up of alpha, beta and two gamma subunits, regulates intracellular cGMP levels by h

248 ions of the N- and C-terminal helices of the gamma subunit, respectively, to identify the segment(s)

249 of catalytic-alpha and regulatory beta- and gamma-subunits, responding to low cellular nucleotide ch

250 To understand the gamma subunit role in the catalytic mechanism, we previo

251 In F(1), the central gamma subunit rotates inside the alpha(3)beta(3) ring.

252 ions, and to make compensatory new ones, the gamma-subunit rotates through 25 degrees -30 degrees .

253 the rate-limiting transition state involving gamma subunit rotation.

254 ecular dynamics simulations of torque-driven gamma-subunit rotation in the F1-ATPase rotary motor.

255 ential for ATP synthesis, and cannot convert gamma-subunit rotation into the conformational changes i

256 ineffective coupling of the chemistry to the gamma-subunit rotation.

257 in an EF hand of CaM and in a region of the gamma subunit sharing high sequence similarity with the

258 s partially rescued by overexpression of the gamma subunit, suggesting a role for this region in gamm

259 a - 1, alpha -2/delta, beta, and gamma), the gamma subunit that comprises an eight-member protein fam

260 lular allosteric regulatory subdomain of the gamma subunit that has an important role in conferring t

261 le alpha or beta, and it is instead the F(1) gamma subunit that initiates the release of the chaperon

262 We sought to determine whether gamma subunits that are expressed in cardiac tissue phys

263 ) proteins have been identified as auxiliary gamma subunits that elevate the voltage sensitivity of r

264 ed alterations of the Gal83 (beta) and Snf4 (gamma) subunits that relieve glucose inhibition, and we

265 with the beta-subunit and the other with the gamma-subunit that appear to be necessary for the struct

266 nd a concomitant 120 degrees rotation of the gamma-subunit, the interface closes further to the alpha

267 ein-protein interactions with its inhibitory gamma-subunit, the prenyl-binding protein (PrBP/delta),

268 ) of the inhibitor of NF-kappaB kinase (IKK) gamma subunits, thereby activating IKK.

269 TP molecules induces rotation of the central gamma-subunit, thereby forcing the site to transform thr

270 es of the catalytic beta-subunits act on the gamma-subunit through repulsive van der Waals interactio

271 edox modulation of a disulfide bridge on the gamma-subunit through the ferredoxin-thioredoxin regulat

272 e that interacts with the common Fc receptor gamma subunit to initiate immune signaling.

273 subunit epsilon engages the alpha, beta and gamma subunits to lock the enzyme and prevent functional

274 from the fetal acetylcholine receptor (AChR) gamma-subunit to the adult epsilon-subunit.

275 ral elements for differential binding of the gamma-subunit to the GAFa domains of the alpha- and beta

276 Depending on the gamma subunit, translocation occurs predominantly to the

277 ide of Arf1 binds to the central part of the gamma subunit trunk of a second AP-1 complex.

278 e rate of translocation also varies with the gamma subunit type.

279 Translocation rates differ depending on the gamma subunit type.

280 Oscillations in HeLa cells expressing gamma subunit types with different translocation rates w

281 membrane dissociation rates among different gamma-subunit types to differentially control betagamma-

282 set of basic and hydrophobic residues in the gamma-subunit types.

283 was caused by an altered redox state of the gamma-subunit under low, but not high, light.

284 Driven by a proton flux, the F1 asymmetric gamma subunit undergoes a stepwise rotation inside the a

285 is, immunoreactivity to ENaC alpha, beta and gamma subunits was detected both by Western blot and imm

286 Overexpression or silencing of the ENaC gamma-subunit was associated with parallel and specific

287 ta-subunit and sucrose nonfermenting4 as the gamma-subunit was constructed to examine functional aspe

288 We observed that only the beta and gamma subunits were modified by Cys palmitoylation.

289 attempts to disrupt genes encoding beta and gamma subunits were unsuccessful, suggesting an essentia

290 f GRK2 with receptors or with G protein beta-gamma subunits which are differentially promoted by agon

291 gG- and IgM-antibodies against the beta- and gamma-subunits which had been recombinant expressed in E

292 of epithelial Na(+) channel (ENaC) alpha and gamma subunits, which associated with a lower baseline p

293 We demonstrate that cleavage of the gamma-subunit, which is critical for full channel activa

294 xperiments probing different segments of the gamma-subunit, which resolves a long-lasting controversy

295 -ray structure is enforced sterically by the gamma subunit whose orientation is stabilized by interac

296 ents in oocytes expressing channels carrying gamma subunits with both a mutation in the furin cleavag

297 nonequivalence of human Hb alpha, beta, and gamma subunits with respect to redox reactivity and may

298 region, is reduced allowing rotation of the gamma-subunit with less impedance.

299 They are made up of alpha, beta, and gamma subunits, with 16 Galpha, 5 Gbeta and 12 Ggamma su

300 sm is coupled to the rotation of the central gamma subunit working as a ratchet but with structural d