ライフサイエンスコーパス: gap junction protein

1 ncreased level of connexin 43, an astroglial gap junction protein.

2 ock-out (KO) mice for connexin36, a neuronal gap junction protein.

3 onnexin 43 (Cx43), the most widely expressed gap junction protein.

4 a molecular crosstalk between desmosomal and gap junction proteins.

5 hrough persistent expression and function of gap junction proteins.

6 nexin1, a vertebrate homolog of invertebrate gap junction proteins.

7 eir mammalian homologues, the pannexins, are gap junction proteins.

8 ny known intercellular adhesion proteins and gap junction proteins.

9 of this regulation, we studied photoreceptor gap junction proteins.

10 or by pannexins, a newly described family of gap junction proteins.

11 tion channels and subsequently internalizing gap junction proteins.

12 on levels or posttranslational processing of gap junction proteins.

13 f cells within tissues that are connected by gap junction proteins.

14 ression of connexin 43 (Cx43) (also known as gap junction protein alpha 1 [GJA1]).

15 how that de novo missense mutations in GJA1 (gap junction protein alpha 1) cause EKVP.

16 ction with ACTN1 (alpha-actinin 1) and GJA1 (gap junction protein alpha 1), 2 sarcolemma-associated p

17 anslated small C terminus isoform, GJA1-20k (Gap Junction Protein Alpha 1- 20 kDa), which is required

18 35, and a candidate gene (GJA4) encoding the gap junction protein alpha-4 (connexin 31, Cx31) was exc

19 oglein (DSG)1, tight junction protein 2, and gap junction protein alpha.

20 ly unidentified proteolytic targeting of the gap junction protein, alpha 1(GJA1); however, surprising

21 + mice carry a mutation in one allele of the gap junction protein alpha1 gene (Gja1), resulting in a

22 pled VBN neurons require Cx36 but that other gap junction proteins also contribute.

23 Fibrosis, cellular dysfunction, and gap junction protein alterations occur in AF and cause c

24 hy chordates seem to exclusively use the new gap junction protein and why no chordates should exist t

25 We analyzed the effects of mutating gap junction proteins and blocking neuromuscular transmi

26 Our data demonstrate a novel role for gap junction proteins and suggest gap junction-mediated

27 d expression of connexin 36 (Cx36) (neuronal gap junction protein), and inactivation of group II mGlu

28 Although mutations in ion channels, gap junction proteins, and signaling molecules have been

29 Connexins (Cxs) are the main mammalian gap junction proteins, and the distribution of some Cx s

30 uence homology to innexins, the invertebrate gap junction proteins, and which also shares topological

31 These gap junction proteins are expressed with overlapping cel

32 servations indicate that although astrocytic gap junction proteins are maintained at high levels thro

33 nd expression of connexin 36 (Cx36; neuronal gap junction protein) are regulated by an interplay betw

34 tions in one gene, connexin 26 (encoding the gap junction protein beta 2), may be responsible for hal

35 We report a missense mutation in the gap junction protein beta-3 (encoding Connexin 31), whic

36 yopathy, a 308,769 base pair deletion in the Gap Junction Protein, beta 6 (GJB6) gene that causes Hea

37 Mutations in GJB2 (gap junction protein, beta-2) are the major cause of aut

38 cytes from human articular cartilage express gap junction proteins called connexins (Cxs).

39 of a set of diseases caused by mutations in gap junction proteins called connexins.

40 Functional expression of gap junction proteins can be obtained conveniently with

41 Dynamically regulated expression of the gap junction protein connexin (Cx)43 plays pivotal roles

42 the proper function and distribution of the gap junction protein connexin (Cx)43.

43 Mutations in the gene encoding the cochlear gap junction protein connexin 26 (CX26) cause prelingual

44 The gap junction protein connexin 26 (Cx26) has been detecte

45 including a significant upregulation of the gap junction protein connexin 26 (Cx26).

46 tly, mutations in the GJB6 gene encoding the gap junction protein connexin 30 have been shown to caus

47 ents with mutations in the gene encoding the gap junction protein connexin 32 (Cx32), which is expres

48 ents with mutations in the gene encoding the gap junction protein connexin 32 (Cx32).

49 ganglion cells in mice lacking the neuronal gap junction protein connexin 36 (Cx36) have nearly norm

50 Utilizing islets from a gap junction protein connexin 36 knockout mouse model to

51 signaling, and required the presence of the gap junction protein connexin 36.

52 s homeodomain-only protein and GATA4 and the gap junction protein connexin 40.

53 A recent study showed that gap junction protein connexin 43 (Cx43) and desmosome pr

54 s indicate that the expression levels of the gap junction protein connexin 43 (cx43) are profoundly d

55 The gap junction protein Connexin 43 (Cx43) contributes to c

56 ltered expression and function of astroglial gap junction protein connexin 43 (Cx43) has increasingly

57 ession and distribution of the intercellular gap junction protein connexin 43 (Cx43) in dogs.

58 The gap junction protein connexin 43 (Cx43) is absent in the

59 Lateralization of the ventricular gap junction protein connexin 43 (Cx43) occurs in epicar

60 Recent studies indicate that the gap junction protein connexin 43 (Cx43) renders GBM cell

61 Astrocytic tumors express the gap junction protein connexin 43 (Cx43), and we show her

62 estricted to intercalated discs and binds to gap junction protein connexin 43 (Cx43).

63 blast growth factor (bFGF), NPCs express the gap junction protein connexin 43 and are dye-coupled.

64 e comparison of Kit immunoreactive cells and gap junction protein connexin 43 in both small intestine

65 sion of several contractile proteins and the gap junction protein connexin 43 through cAMP/PKA signal

66 sion of several contractile proteins and the gap junction protein connexin 43 through cAMP/PKA signal

67 d cytoplasmic HDAC3 forms a complex with the gap junction protein Connexin 43 to modulate the BTB int

68 in and beta1D integrin were reduced, and the gap junction protein connexin 43 was mislocalized to the

69 the localization pattern and function of the gap junction protein connexin 43 were examined in vivo i

70 src produces tyrosine phosphorylation of the gap junction protein connexin 43, decreases gap junction

71 junction-associated proteins, including the gap junction protein Connexin 43, facilitating scattered

72 utations in the gene GJA1, which encodes the gap junction protein connexin 43, underlie oculodentodig

73 mined whether dysregulated expression of the gap junction protein connexin 43, which has been observe

74 UMR 106-01 cells predominantly express the gap junction protein connexin 45 (Cx45), are poorly dye

75 reflected decreased expression levels of the gap junction protein connexin 46 (Cx46).

76 nant mutations in the GJB2 gene encoding the gap junction protein connexin-26, suggesting an etiologi

77 from mutations in the gene GJB3 encoding the gap junction protein connexin-31 (Cx31).

78 rm running on the expression of the neuronal gap junction protein connexin-36 among inhibitory intern

79 ative IIF, and even cell strains lacking the gap junction protein connexin-36 exhibited nonnegligible

80 It is known that the gap junction protein connexin-36 is widely expressed in

81 Aberrant expression of the cardiac gap junction protein connexin-43 (Cx43) has been suggest

82 tion, other signaling molecules, such as the gap junction protein connexin-43 (Cx43), also influence

83 ely invading breast cancer cells express the gap junction protein connexin-43 (Cx43), yet whether Cx4

84 ocity correlated with a 53% reduction in the gap junction protein connexin-43.

85 Mutations in the genes encoding for gap junction proteins connexin 26 (Cx26) and connexin 30

86 Mutations in the genes encoding for gap junction proteins connexin 26 (Cx26) and connexin 30

87 s, the transcription factor Hf1b/Sp4 and the gap junction proteins connexin 40 and connexin 43 were m

88 entified a mutation in the gene encoding the gap-junction protein connexin 26 (Cx26) that segregates

89 ated desmosomal protein plakoglobin, and the gap-junction protein connexin-43.

90 To define further the mechanisms of gap junction protein (connexin (Cx)) oligomerization wit

91 mapped previously to 6q25-26, human cardiac gap junction protein (connexin 43) mapped previously to

92 s cells without detectably increasing either gap junction protein (connexin) synthesis or assembly.

93 y understood but probably involve changes in gap junction protein (connexin) synthesis, assembly into

94 audin 1, 14, 16, and zona occludens 2), nine gap junction proteins (connexin 26, 30, 30.3, 31, 32, 40

95 Previously, we showed that expression of the gap junction protein, connexin (Cx) 43, is increased by

96 synapses) and the expression of the neuronal gap junction protein, connexin 36 (Cx36), transiently in

97 The astrocytic gap junction protein, connexin 43 (Cx43), was identified

98 companied by tyrosine phosphorylation of the gap junction protein, connexin 43 (Cx43).

99 In cultured corneal fibroblasts, the gap junction protein, connexin 43, was highly expressed

100 A significant decrease in the gap junction protein, connexin 43, was observed in the N

101 in tissue culture that expressed a specific gap junction protein, connexin 43.

102 Both WT and Hyp cementocytes expressed gap junction protein, connexin 43.

103 A significant decrease in the gap junction proteins, connexin-43 and connexin-40, was

104 The lens gap-junction protein, connexin 56, is modified by phosph

105 They also express cardiac gap-junction protein, connexin-43, similar to CMs and sy

106 o contiguous genes respectively encoding the gap junction protein connexin26 (Cx26) and connexin 30 (

107 Mutations in the gene GJB2, encoding the gap junction protein Connexin26 (Cx26), are the most pre

108 The isoelectric points of the gap junction proteins connexin26 (Cx26) and connexin32 (

109 l (A88V) mutation in the gene coding for the gap-junction protein connexin30 (Cx30) protects the coch

110 )-mediated degradation of the wild-type (WT) gap junction protein connexin32 (Cx32) is inhibited by m

111 Junction beta1 (GJB1), the gene encoding the gap junction protein connexin32 (Cx32), cause the X-link

112 Mutations in GJB1, the gene encoding the gap junction protein connexin32 (Cx32), cause the X-link

113 ne mutations causing loss of function of the gap junction protein connexin32 (Cx32).

114 d by mutations in the GJB1 gene encoding the gap junction protein connexin32 (Cx32).

115 Here, we show for the first time that a gap junction protein, connexin32 (Cx32), acts as a lung

116 aranodes; these regions contain at least one gap junction protein, connexin32 (Cx32).

117 The major neuronal gap junction protein connexin36 (Cx36) exhibits the rema

118 All these synapses require the gap junction protein connexin36 (Cx36) for robust electr

119 , Christie et al. use mice deficient for the gap junction protein connexin36 (Cx36) to demonstrate th

120 ctrical synapses that depend strongly on the gap junction protein connexin36 (Cx36).

121 ectrical synapses, most of which require the gap junction protein connexin36 (Cx36).

122 ermal N-cadherin, Zonula Occludens-1 and the gap junction protein Connexin43 (Cx43) compared to intac

123 The gap junction protein connexin43 (Cx43) forms intercellul

124 ytes might release ATP; however, whether the gap junction protein connexin43 (Cx43) forms these "hemi

125 NNB1), showed increased association with the gap junction protein connexin43 (Cx43) in PG CKO hearts.

126 and epithelial responses at the level of the gap junction protein connexin43 (Cx43) in polarized huma

127 trate a previously unrecognized role for the gap junction protein connexin43 (Cx43) in the regulation

128 To characterize the role of the gap junction protein connexin43 (Cx43) in ventricular co

129 The gap junction protein connexin43 (Cx43) is a tumor suppre

130 dification-induced regulation of the cardiac gap junction protein connexin43 (Cx43) may be modeled as

131 that in cultured myocytes, rapid loss of the gap junction protein connexin43 (Cx43) occurs in conjunc

132 erize in the endoplasmic reticulum (ER), the gap junction protein connexin43 (Cx43) oligomerizes in a

133 We targeted the gap junction protein connexin43 (Cx43) responsible for m

134 Hemodynamic regulation of the endothelial gap junction protein connexin43 (Cx43) was studied in a

135 ROS 17/2.8 cells, which express the gap junction protein connexin43 (Cx43), are well dye cou

136 fic mutations in GJA1, the gene encoding the gap junction protein connexin43 (Cx43), cause an autosom

137 accompanied by overt mislocalization of the gap junction protein connexin43 (Cx43).

138 The gap junction protein connexin43 (Cx43, gene name GJA1) f

139 Regulation of cell-cell communication by the gap junction protein connexin43 can be modulated by a va

140 tic modification of myoblasts to express the gap junction protein connexin43 decreased arrhythmogenic

141 The gap junction protein connexin43 followed a similar but d

142 Fusions of the gap junction protein connexin43 to mRFP1 formed fully fu

143 in phospholamban, and a 60% reduction in the gap junction protein connexin43, relative to neighboring

144 o express individual P2 receptors and/or the gap junction protein connexin43.

145 s in primary ovine lens cultures express the gap junction proteins connexin43 (Cx43) and connexin49 (

146 ed that the total amounts of the ventricular gap junction proteins connexin43 and connexin45 (Cx43 an

147 The gap junction protein, connexin43 (Cx43), has critical ro

148 In this study, we examine the role of the gap junction protein, connexin43 (Cx43), in the transcri

149 Although the major cardiac gap junction protein, connexin43 (Cx43), is expressed ab

150 The half-life of the principal cardiac gap junction protein, connexin43 (Cx43), is only 1.5 to

151 nges in phosphorylation of the major cardiac gap junction protein, connexin43 (Cx43).

152 and immunoconfocal analysis showed that the gap junction protein, connexin43, was widely and persist

153 Odontoblasts expressed the gap junction protein, connexin43, which can form transme

154 Wnt signaling, followed by the expression of gap junction protein, connexin43.

155 Two gap junction proteins, connexin43 (Cx43) and connexin45

156 ons in GJA12/GJC2, the gene that encodes the gap junction protein connexin47 (Cx47), cause Pelizaeus-

157 The lens fiber cell-specific gap junction protein connexin49 is a substrate for a mem

158 onstrated TPA-induced phosphorylation of the gap junction protein connexin56 (Cx56).

159 Gap junction proteins (connexins) facilitate intercellul

160 derstanding the functional roles of specific gap junction proteins (connexins) in brain, lens, retina

161 tion studies in mice have revealed roles for gap junction proteins (connexins) in heart development.

162 So far all gap junction proteins (connexins), with the exception of

163 e have revealed some unexpected roles of the gap junction proteins (connexins).

164 how that in valved veins of the mouse, three gap junction proteins (Connexins, Cxs), Cx37, Cx43, and

165 Ectopic expression of gap junction proteins, connexins (Cxs), leads to an incr

166 Lens gap junction proteins, connexins [1], are known to be ph

167 Forced expression of gap junction proteins, connexins, enables gap junction-d

168 Phosphorylation of gap junction proteins, connexins, plays a role in global

169 Loss-of-function mutations of gap junction proteins, connexins, represent a mechanism

170 x (ECM) protein deposition and disruption of gap junction proteins, connexins.

171 ding for ion channel proteins, including the gap junction proteins, connexins.

172 genetically engineering cells to overexpress gap junction proteins, could enhance cell differentiatio

173 fy motifs involved in oligomerization of the gap junction protein Cx26, we studied individual transme

174 c.148G>A, p.D50N) in the GJB2 gene, encoding gap junction protein Cx26, which alters gating propertie

175 atal and adult rats, and we propose that the gap junction proteins Cx26 and Cx32 form the neuroanatom

176 ectrical synapses composed of the vertebrate gap junction protein Cx36 between Caenorhabditis elegans

177 or example, such studies have implicated the gap junction protein Cx36 in synchronizing rhythmic acti

178 sing histochemical reporters in place of the gap junction protein Cx36.

179 microscopy, and confocal microscopy for the gap junction protein Cx36.

180 ibronectin EIIIA, Foxc2, calcineurin and the gap junction protein Cx37 are required for lymphatic val

181 monstrated that the carboxyl terminus of the gap junction protein Cx43 (Cx43CT) can act as an indepen

182 binds to a specific region of the ubiquitous gap junction protein Cx43 in a Ca(2+)-dependent manner,

183 al protein plakoglobin and the major cardiac gap junction protein Cx43 were markedly diminished in bu

184 scriptional repression of GJA1 (encoding the gap junction protein Cx43) and other genes related to in

185 increased the expression and distribution of gap junction protein Cx43, which became reduced in ablat

186 ciates with intercalated discs, and integral gap junction proteins Cx43 (connexin 43), Cx45 (connexin

187 The gap junction protein, Cx43, plays a pivotal role in coup

188 The gap junction protein, Cx43, was expressed intensively ar

189 Changes in expression of the cardiac gap junction protein, Cx43, were measured by confocal mi

190 ycle (assembly, gating, and turnover) of the gap junction protein, Cx43.

191 xes, either directly and/or indirectly, with gap junction proteins Cx46 and Cx50 that are often assoc

192 rial osteoblastic cells also express another gap junction protein, Cx46.

193 ine also blocked channels formed by the lens gap junction protein, Cx50 (IC(50) approximately 1.1 mic

194 Lens fiber cells contain two gap junction proteins (Cx56 and Cx45.6 in the chicken).

195 y mutations in GJB1, which codes for Cx32, a gap junction protein expressed by Schwann cells and olig

196 Connexin (Cx) 26, a major gap junction protein expressed in mammary epithelial cel

197 nexin 40 (Cx40), a developmentally regulated gap junction protein expressed in motor and other spinal

198 Connexin43 (Cx43) is a major gap junction protein expressed in the mammalian heart an

199 We provide evidence that gap junction proteins, expressed during development, are

200 Analyses of gap junction protein expression in cat and rat showed th

201 al coupling and dye coupling and patterns of gap junction protein expression in lumbar spinal motor n

202 Gap junction proteins form the substrate for electrical

203 3 and Cx43 are the most abundantly expressed gap junction proteins from each family.

204 Deficiencies in the gap junction protein gene connexin 40 (Cx40), a downstre

205 l pathology characterized by upregulation of gap junction protein GJA1, water channel AQP4, and lipid

206 concomitant with increased expression of the gap junction protein Gja1.

207 ood vessels, and decreased expression of the gap junction protein Gjb2 (Cx26).

208 Epithelial expression variance of gap junction protein GJB6 increased with age, and modula

209 anscription factors Foxc2 and Nfatc1 and the gap junction proteins Gjc2, Gja1, and Gja4 were temporos

210 Loss or reduction in the levels of the gap junction protein Gjd2b decreased the frequency of gl

211 However, no specific gap junction protein has yet been functionally linked to

212 ylation of members of the connexin family of gap junction proteins has been correlated with gap junct

213 Macrophages that lack connexin43 (Cx43), a gap junction protein, have been reported to exhibit dram

214 regulating factors is Connexin 43 (Cx43), a gap junction protein highly expressed by astrocytes at t

215 Here we show a novel role for a gap junction protein in controlling tiled synaptic arran

216 increased strong expressions of connexin 43 gap junction protein in heart and lung specimens by immu

217 Connexin43 (Cx43) is the most abundant gap junction protein in higher vertebrate organisms and

218 in serine phosphorylation on the connexin-43 gap junction protein in T51B rat liver epithelial cells.

219 Connexin32 (Cx32) is a major gap junction protein in the liver and brain.

220 The primary gap junction protein in the working myocardium, connexin

221 transgenic mouse models that implicate glial gap junction proteins in demyelinating diseases and the

222 led that connexin43 (Cx43), one of the major gap junction proteins in human vascular endothelial cell

223 This study examined whether innexins, gap junction proteins in insects, are involved in anti-P

224 r in addition to their conventional roles as gap junction proteins in lens cells.

225 Our work points to an important role for gap junction proteins in mediating insulation by non-mye

226 he complete description of the expression of gap junction proteins in the nervous system of the worm

227 pression of the two most abundant astrocytic gap junction proteins in young and senescent brains and

228 ique to chordates; innexins/pannexins encode gap-junction proteins in prechordates and chordates.

229 of connexin-43 (Cx43), the major ventricular gap junction protein, in DMD cardiomyopathy.

230 us of Drosophila encodes a germline-specific gap junction protein, Innexin 4, that is required for su

231 Connexin-43 (Cx43), a gap junction protein involved in control of cell prolife

232 n and increased expression of connexin 43, a gap junction protein involved with labor.

233 show that electrical synapses formed by the gap junction protein INX-1/innexin couple the presynapti

234 In addition, messenger RNA for gap junction proteins is expressed in motoneurons of the

235 +-dependent inhibition of the alpha-class of gap junction proteins is mediated by the direct associat

236 Connexin 43 (gap junction protein) is expressed in pigmented and albi

237 lular communication (GJIC) and/or connexins (gap junction proteins) is frequently reported in maligna

238 trate that connexin 32 (Cx32), a key hepatic gap junction protein, is an essential mediator of DILI b

239 nnexin43 (Cx43), the predominant ventricular gap junction protein, is critical for maintaining normal

240 Connexin 32 (Cx32), a gap junction protein, is found within the para-nodal reg

241 he expression of connexin 43 (Cx43), a major gap junction protein, is markedly enhanced in response t

242 ion of Cx43 (connexin 43), the major cardiac gap junction protein, is often associated with arrhythmi

243 e regulation of expression of connexin 43, a gap junction protein, is part of the transduction mechan

244 riate AV node conduction through maintaining gap junction protein localization.

245 ealed the presence of Cx43, the main cardiac gap junction protein, localized to cell-cell borders.

246 vious studies suggested that the connexin-43 gap junction protein may be a target of activated MAP ki

247 Gap junction proteins mediate signaling communication by

248 determine whether the pre-BotC contains the gap junction proteins necessary for electrotonic communi

249 Instead, sharing requires gap junction proteins (normally associated with transpor

250 ning, we found that dco encodes Gja3/Cx46, a gap junction protein not previously implicated in heart

251 at a transient network formed by the innexin gap-junction protein NSY-5 coordinates left-right asymme

252 The principal gap junction protein of intercellular communication, con

253 -cadherin and connexin43, major adhesion and gap junction proteins of the intercalated disk, yet both

254 the PKCgamma phosphorylated the connexin 43 gap junction proteins on Ser-368.

255 Here, we report that gap junction proteins, or connexins (Cxs), are required

256 ormed this study to test the hypothesis that gap junction protein overexpression would improve conduc

257 iological data that erythrocytes express the gap junction protein pannexin 1.

258 0 quantity (rs=0.54, P=0.01, n=20), and Cx40 gap-junction protein per unit area of en face disk (rs=0

259 Connexin(Cx)43 is the major gap junction protein present in osteoblasts.

260 ngly, we investigated whether connexin 43, a gap junction protein present in the basal layer of norma

261 (Cx37) or connexin40 (Cx40), the predominant gap junction proteins present in vascular endothelium, a

262 d early increases in connexin 26, a cochlear gap junction protein previously shown to interact with F

263 The gene for the connexin 26 gap junction protein, recently shown to be mutant in bot

264 interaction between glutamate receptors and gap junction proteins represents a novel mechanism for r

265 2, also known as Gjd3) gene, which encodes a gap junction protein required for normal atrioventricula

266 decreased expression of Cx43, the principal gap junction protein responsible for propagating current

267 a cells transfected with the lens fiber cell gap junction protein sheep Cx44 also results in the inhi

268 ether the presence and distribution of these gap junction proteins show a developmental change in exp

269 Pannexin 1 (Panx1) is a novel gap junction protein shown to have tumor-suppressive pro

270 Our data shows that connexin 36, a gap junction protein specific to neurons, is most densel

271 ously described in psoriasis--connexin 26, a gap junction protein; squamous cell carcinoma antigen-1

272 despite the persistent expression of several gap junction proteins suggests that gap junctional commu

273 al uncoupling, but the preservation of other gap junction proteins supports slow action potential pro

274 Connexin43 (Cx43) is a gap junction protein that forms multimeric channels that

275 Connexin40 (Cx40) is an abundant gap junction protein that is expressed in atrial myocyte

276 Connexin40 (Cx40) is a major gap junction protein that is expressed in the His-Purkin

277 Pannexin-3 (Panx3) is a gap junction protein that is required for regulating cel

278 Connexin26 (Cx26) is a gap junction protein that oligomerizes in the cell to fo

279 Connexin26 is a ubiquitous gap junction protein that serves critical homeostatic fu

280 neurons may occur by modulation of existing gap junction proteins that are constitutively expressed

281 Connexins are gap junction proteins that form aqueous channels to inte

282 f related connexin genes encodes the subunit gap junction proteins that form intercellular channels i

283 expression gradients of calcium handling and gap junction proteins that may worsen chamber function a

284 etween AMPA-type glutamate receptors and the gap junction proteins that mediate electrical synaptic t

285 tion of nerve signaling results in a loss of gap junction protein, the reentry of the cells into the

286 res topological similarities with vertebrate gap junction proteins, the connexins.

287 romes have been linked to mutations in glial gap junction proteins, the connexins.

288 t osteosarcoma cell lines that differ in the gap junction proteins they express, in their ability to

289 eduction in the abundance of a major cardiac gap junction protein through targeted deletion of a Cx43

290 nd chemicals require connexin (Cx) 32, a key gap junction protein, to induce hepatotoxicity.

291 Immunostaining for gap junction proteins was performed on SIDS-associated p

292 Connexin 43, a cardiac gap junction protein, was expressed between grafted cell

293 enes assessed, those encoding laminins and a gap junction protein were upregulated in Mmp20(-/-) mice

294 Recently, connexin35/36 (Cx35/36) gap junction proteins were found to be highly expressed

295 GJB2 encodes connexin 26, a gap junction protein, which permits intercellular ion an

296 he colocalization of connexin43 (Cx43alpha1) gap junction protein with N-cadherin, p120, and other N-

297 nsmembrane/first extracellular domain of the gap junction protein with the mutation replacing a negat

298 cardiac growth factor that leads to loss of gap junction proteins within a spatially confined microe

299 Here we show that the gap junction protein Zero population growth (Zpg) is req

300 the downregulated genes were connexin-31, a gap junction protein; ZO1 and occludin, tight junction p