ライフサイエンスコーパス: gastrin

1 cells, to assess proliferative responses to gastrin.

2 sphorylation and cell motility stimulated by gastrin.

3 ity to the regulation of G-cell secretion of gastrin.

4 TFF1, which can be suppressed by the hormone gastrin.

5 , gastric acid content, and plasma levels of gastrin.

6 eptor for cholecystokinin (CCK) and amidated gastrin.

7 ccurring forms and extensive similarities to gastrin.

8 een associated with elevated levels of serum gastrin.

9 otection against injury by administration of gastrin.

10 timulates the G-cells to produce and secrete gastrin.

11 ecificity, phytaspase was shown to hydrolyze gastrin-1 and cholecystokinin at the predicted sites in

12 e normal, except for the elevation of plasma gastrin (1031 pg/ml; reference value <108) and chromogra

13 f pepsinogen 1 (PG1), pepsinogen 2 (PG2) and gastrin 17 (G17) offers the possibility to detect preneo

14 ected for Helicobacter pylori, HIV serology, gastrin-17, and pepsinogen 1 and 2 concentrations.

15 tokinin-2 receptor was treated with amidated gastrin-17.

16 vasoactive intestinal peptide (5 patients), gastrin (2 patients), or glucagon (4 patients).

17 l (nl <2.5), PTH i = 243 pg/mL (nl <65), and gastrin = 6950 pg/mL (nl < 100).

18 In mice genetically deficient in gastrin, a key regulator for gastric acid production, or

19 orectal cancer, FAK is activated by amidated gastrin, a protumorigenic hormone.

20 Here we show that gastrin, a stomach hormone typically expressed in the pa

21 mulants of acid secretion include histamine, gastrin, acetylcholine, and ghrelin.

22 Gastrin, acting via cholecystokinin-2 receptors on enter

23 Gastrin, acting via gastrin/cholecystokinin-B (CCK-B), n

24 and HDAC7 with HDC promoter, suggesting that gastrin activates HDC gene expression at least partly by

25 erum inflammatory mediators, antibodies, and gastrin among germfree and H pylori-monoinfected INS-GAS

26 letion of the pentaglutamate sequence in the gastrin analogs lowered the tumor uptake by a factor of

27 The use of radiolabeled gastrin analogs targeting the cholecystokinin-2 receptor

28 n-L, might be involved in the degradation of gastrin analogs.

29 ognized for decades as potent stimulants for gastrin and acid secretion, although the molecular basis

30 pecific calcimimetic, cinacalcet, stimulated gastrin and acid secretion, whereas the calcilytic, NPS

31 as the elusive physiologic sensor regulating gastrin and acid secretion.

32 matory infiltrate are capable of stimulating gastrin and acid secretion.

33 the human gastrointestinal peptide hormones gastrin and cholecystokinin.

34 Both gastrin and gastrin-receptor knockout mice as well as ga

35 wth factor gastrin, and mice mutant for both gastrin and Hip1r exhibited normalization of both prolif

36 L cells are coupled by the couplet molecules gastrin and histamine and by a prior asymmetrical cell d

37 A chemical complex of gastrin and histamine is postulated as is also the asymm

38 tric cancer in INS-GAS mice that overexpress gastrin and IL-8Tg mice infected with Helicobacter felis

39 one has led to new research into the role of gastrin and its receptor (cholecystokinin-2 receptor) in

40 through the upregulation of plasma levels of gastrin and matrix metalloproteinase expression.

41 We also found that the levels of gastrin and p73 transcripts correlate in primary gastric

42 lates all enteroendocrine cell types, except gastrin and preproglucagon.

43 cells from C57BL/6 mice were incubated with gastrin and separated into nuclear and cytoplasmic fract

44 Moreover, gastrin and Sst gene expression did not change in respon

45 as a new effector for Galpha13 downstream of gastrin and the type 2 cholecystokinin receptor.

46 retion from the parietal cell are histamine, gastrin, and acetylcholine.

47 stimulants of acid secretion are histamine, gastrin, and acetylcholine.

48 centages of circulating intact somatostatin, gastrin, and bombesin radiopeptides in mouse models, res

49 d decrease in antral cilia, increased plasma gastrin, and gastric acidity.

50 ased expression of the gastric growth factor gastrin, and mice mutant for both gastrin and Hip1r exhi

51 red that membrane-associated ANX II binds PG/gastrins, and partially mediates growth factor effects o

52 rming growth factor-alpha, amphiregulin, and gastrin; and activation of extracellular signal-regulate

53 These results reveal the fetal hormone gastrin as a novel marker for reversible human beta-cell

54 cted of possibly having ZES, the appropriate gastrin assay to use, the role of surgery in patients wi

55 2 receptor mRNA abundance and increased 125I-gastrin binding was demonstrated in IEC-6 cells followin

56 d earlier reported the presence of 33-36 kDa gastrin-binding proteins on cellular membranes of colon

57 Diffuse gastrin cell hyperplasia precedes the appearance of MEN1

58 n parietal, enterochromaffin-like (ECL), and gastrin cells.

59 ence on parietal, enterochromaffin-like, and gastrin cells.

60 production of duodenal GIP cells and stomach gastrin cells.

61 raint on parietal, enterochromaffinlike, and gastrin cells.

62 Gastrin/cholecystokinin subtype 2 receptors (CCK-2Rs) ar

63 The gastrin/cholecystokinin-2 (CCK-2) receptor has been iden

64 Gastrin, acting via gastrin/cholecystokinin-B (CCK-B), now termed CCK2, rece

65 d with increased basal and stimulated plasma gastrin concentrations and acid outputs.

66 had increases in glucagon-like peptide-1 and gastrin concentrations that were expected with treatment

67 fibrillary acidic protein (GFAP+) expressed gastrin de novo through a mechanism that required PKA.

68 investigated in hypergastrinemic (INS-GAS), gastrin-deficient (GAS(-/-)), Tff1-deficient (Tff1(+/-))

69 However, gastrin-deficient (GAS-KO) mice on a mixed C57BL/6/129Sv

70 -Shh(KO)) and hypergastrinemia, crossed with gastrin-deficient (GKO) mice (PC-Shh(KO)/GKO).

71 In contrast, homozygous gastrin-deficient and heterozygous Tff1-deficient mice s

72 Acute parietal cell loss in gastrin-deficient mice treated with DMP-777 leads to the

73 Emerging SPEM lineages in gastrin-deficient mice treated with DMP-777 were examine

74 mined the intracellular mechanisms mediating gastrin-dependent gene expression.

75 Gastrin differentially induces COX-2 and IL-8 expression

76 The peptide hormone gastrin exerts a suppressive effect on antral gastric ca

77 in gene and induces generation of submucosal gastrin-expressing cell hyperplasia.

78 ow)/ Numb(+) and repressed by signaling from gastrin-expressing endocrine (G) cells.

79 Gastrin expression in adult beta-cells does not involve

80 in in mice is expressed in insulin(+) cells, gastrin expression in humans with T2D occurs in both ins

81 In vivo and in vitro experiments show that gastrin expression is rapidly eliminated upon exposure o

82 netic lineage tracing in mice indicates that gastrin expression is turned on in a subset of different

83 Gastrin expression was co-localized with HDC expression

84 The gastrin (from G-cells) stimulates the ECL cells to produ

85 Gastrin, from G-cells, and histamine, from enterochromaf

86 Amidated gastrin (G-17) attenuated the growth suppressing effects

87 roduct of the gastrin gene (glycine-extended gastrin (G-gly)) as a new ligand for the F(1)-ATPase.

88 identified a peptide hormone product of the gastrin gene (glycine-extended gastrin (G-gly)) as a new

89 igated how menin regulates expression of the gastrin gene and induces generation of submucosal gastri

90 ed production of somatostatin, and increased gastrin gene expression.

91 recent developments in the biology of other gastrin gene products, including the precursor progastri

92 tigated the role of p73 in regulation of the gastrin gene promoter.

93 onstrate a novel mechanism for regulation of gastrin gene transcription and support a concept that p5

94 ed and incompletely processed product of the gastrin gene, has been shown to induce colonic hyperprol

95 cyclase-activating peptide), hormonal (e.g., gastrin, ghrelin, and apelin), and paracrine (e.g., hist

96 y cilia on gastric endocrine cells producing gastrin, ghrelin, and somatostatin (Sst), hormones regul

97 rum chromogranin A, neuron-specific enolase, gastrin, glucagon, vasoactive intestinal peptide, pancre

98 ease of enteroendocrine cell types including gastrin-, glucagon/GLP-1-, CCK-, secretin-producing cell

99 ollowing injury, but the effects of amidated gastrin have not previously been assessed.

100 nsforming growth factor-alpha, and endocrine gastrins have been implicated in the tumorigenic potenti

101 Gastrin, histamine, acetylcholine, and ghrelin stimulate

102 The major stimulants of acid secretion are gastrin, histamine, and acetylcholine.

103 Gastrin, histamine, gastrin-releasing peptide, ghrelin,

104 (CCKS) and doubly protonated Tyr12-sulfated gastrin II (GST) resulted in complete loss of SO3 from a

105 meal-stimulated acid secretion by releasing gastrin in a variety of laboratory animals, recent studi

106 uggest a role of processing intermediates of gastrin in colon carcinogenesis.

107 s demonstrate that the trophic properties of gastrin in CRC may be mediated in part by transactivatio

108 Therefore, we investigated the role of gastrin in Helicobacter-associated gastric carcinogenesi

109 cells (eg, p75 and S100B), colocalized with gastrin in human duodenal gastrinomas.

110 Although gastrin in mice is expressed in insulin(+) cells, gastri

111 The existence of the hormone gastrin in the distal stomach (antrum) has been known fo

112 focus on the role of endocrine and autocrine gastrins in colon cancer and review recent advances that

113 udies also provide support for the idea that gastrin, in concert with other hormones, could potential

114 ew we consider important additional roles of gastrin, including regulation of genes encoding proteins

115 Gastrin increased the stability of both COX-2 and IL-8 m

116 reased, whereas gastric acid and circulating gastrin increased.

117 n-positive cells; increased levels of plasma gastrin; increased expression of transforming growth fac

118 Gastrin induced COX-2 and IL-8 expression in AGS-E cells

119 colon carcinoma cells depleted of Galpha13, gastrin-induced FAK Tyr(P)-397 and paxillin Tyr(P)-31 ph

120 Gastrin-induced nuclear export of menin via cholecystoki

121 antagonists of WNT and Smoothened inhibited gastrin-induced proliferation and WNT activity.

122 Ihh signaling mediates gastrin-induced proliferation of epithelial cells in sto

123 Gastrin induces the expression of cyclooxygenase (COX)-2

124 Gastrin infusion of PC PC-Shh(KO)/GKO mice increased exp

125 PC-Shh(KO)/GKO mice were given gastrin infusions for 7 days; gastric surface epithelium

126 d in transgenic mice overexpressing amidated gastrin (INS-GAS) and mice in which hypergastrinemia was

127 , was determined in transgenic FVB/N insulin-gastrin (INS-GAS) mice and Mongolian gerbils as models o

128 Transgenic FVB/N insulin-gastrin (INS-GAS) mice have high circulating gastrin lev

129 Autocrine gastrins, insulin-like growth factor-II, transforming gr

130 Gastrin is a key regulator of gastric acid secretion.

131 Gastrin is a peptide hormone and an important factor in

132 e gastric corpus and antrum, suggesting that gastrin is an essential cofactor for gastric corpus carc

133 Gastrin is involved in the endocrine regulation of gastr

134 The recognition that gastrin is not only a secretagogue but also a trophic ho

135 Gastrin is the only hormone capable of stimulating gastr

136 e that express a human progastrin transgene, gastrin knockout mice, and C57BL/6 mice (controls); the

137 ter secretin stimulation testing, the plasma gastrin level rose to 3789 pg/ml.

138 owed lower cilia numbers and acid but higher gastrin levels than mice fed a standard diet, suggesting

139 In fed Ift88(-/fl) mice, gastrin levels were higher, and gastric acidity was lowe

140 gastrin (INS-GAS) mice have high circulating gastrin levels, and develop spontaneous atrophic gastrit

141 Ngn3(-)(/)(-) mice, which also show reduced gastrin levels, express Nkx6.3 normally.

142 inhibits acid secretion and increases serum gastrin levels, factors strongly associated with cancer

143 f unknown cause and screened for using blood gastrin levels.

144 nstitutive achlorhydria, and elevated plasma gastrin levels.

145 aging studies had lower preoperative fasting gastrin levels; had a longer delay before surgery; more

146 Gastrin-mediated Akt activation was observed to be downs

147 for 42%-69% of cells in gerbils and insulin-gastrin mice with dysplasia and carcinoma.

148 both wild-type and hypergastrinemic insulin-gastrin mice, using immunohistochemistry and flow cytome

149 These mice show markedly reduced gastrin mRNA, many fewer gastrin-producing (G) cells in

150 his leads to transcriptional upregulation of gastrin mRNA.

151 We have shown previously that gastrin-null mice display gastric atrophy and metaplasia

152 These results point to a distinct effect of gastrin on carcinogenesis of both the gastric corpus and

153 We therefore investigated the effects of gastrin on intestinal regeneration following a range of

154 amma expression might mediate the effects of gastrin on the proliferation of colorectal cancer (CRC).

155 nd gastrin-receptor knockout mice as well as gastrin-overexpressing and cAMP-overexpressing mice deve

156 -tetraacetic acid (DOTA)-conjugated divalent gastrin peptides based on the C-terminal sequence of min

157 ynthesized and screened a series of divalent gastrin peptides for improved biochemical and biologic c

158 o-labeled gastrins to membrane proteins from gastrin/PG responsive cell lines.

159 ow markedly reduced gastrin mRNA, many fewer gastrin-producing (G) cells in the stomach antrum, hypog

160 Our results show that p73 can bind to the gastrin promoter.

161 (400 ppm in drinking water) alone, the CCK2/gastrin receptor antagonist YM022 (45 mg/kg/wk) alone, a

162 is unclear how FAK receives signals from the gastrin receptor or other G-protein-coupled receptors th

163 e variants of the cholecystokinin-2 (CCK(2))/gastrin receptor; however, their relative contributions

164 Both gastrin and gastrin-receptor knockout mice as well as gastrin-overex

165 ported the presence of novel progastrin (PG)/gastrin receptors on normal and cancerous intestinal cel

166 LD-1 expressed both functional PPARgamma and gastrin receptors.

167 te with gastric atrophy, we examined whether gastrin regulates Shh expression in parietal cells.

168 Gastrin release was stimulated by forskolin (adenosine 3

169 Gastrin release was stimulated by neuronal G protein-cou

170 hanical strain stimulated (2-fold to 8-fold) gastrin release, and decreasing pH from 7.4 to 5.5 inhib

171 onist MRS1754 inhibited mechanically induced gastrin release.

172 The antral hormone gastrin, released by activation of cholinergic and bombe

173 Pro-gastrin releasing peptide (pro-GRP) was identified as a

174 says are in high demand, and analysis of pro-gastrin releasing peptide (ProGRP) as a small cell lung

175 Bioconjugate affinity for the gastrin releasing peptide receptor (GRPR) as determined

176 Gastrin releasing peptide receptor (GRPR) is an attracti

177 , we show that the spinal neurons expressing gastrin releasing peptide receptor (GRPR) primarily comp

178 into tumor cells, their affinity toward the gastrin releasing peptide receptor (GRPr), metabolic sta

179 e been proposed for diagnosis and therapy of gastrin releasing peptide receptor (GRPR)-expressing tum

180 Gastrin releasing-peptide (GRP) is a potent growth facto

181 483 cells with siRNA causes an inhibition of gastrin-releasing peptide (GRP) -induced phosphorylation

182 halocyanine-peptide conjugates targeting the gastrin-releasing peptide (GRP) and integrin receptors i

183 The gastrin-releasing peptide (GRP) and its receptor (GRPR)

184 for the oncogenic transformations induced by gastrin-releasing peptide (GRP) and its receptor, GRP-R,

185 of a cohort of itch-sensing genes, including gastrin-releasing peptide (GRP) and MAS-related GPCR mem

186 NeuroD2 that contribute to these processes: gastrin-releasing peptide (GRP) and the small conductanc

187 al horn excitatory interneurons that express gastrin-releasing peptide (GRP) are part of the circuit

188 Bombesin (BN) or gastrin-releasing peptide (GRP) can stimulate the growth

189 only vasoactive intestinal polypeptide (VIP)/gastrin-releasing peptide (GRP) cells located ventrally

190 Gastrin-releasing peptide (GRP) functions as a neurotran

191 ctions of spinal opioid-related peptides and gastrin-releasing peptide (GRP) in awake, behaving monke

192 Brief light pulses or microinjection of gastrin-releasing peptide (GRP) into the third ventricle

193 Gastrin-releasing peptide (GRP) is a neuropeptide that a

194 Gastrin-releasing peptide (GRP) is a spinal itch transmi

195 Previous studies suggested that gastrin-releasing peptide (GRP) is an itch-specific neur

196 Gastrin-releasing peptide (GRP) is localized to the SCN

197 Gastrin-releasing peptide (GRP) is synthesized by pulmon

198 ning the adult colon do not normally express gastrin-releasing peptide (GRP) or its receptor (GRPR).

199 Gastrin-releasing peptide (GRP) receptors (GRPr) are fre

200 tides have demonstrated high affinity toward gastrin-releasing peptide (GRP) receptors in vivo that a

201 We have previously shown that gastrin-releasing peptide (GRP) stimulates neuroblastoma

202 The gastrin-releasing peptide (GRP) system in the lumbosacra

203 Previously, we determined that gastrin-releasing peptide (GRP) was elevated within days

204 Two probes for gastrin-releasing peptide (GRP), a known stimulatory ago

205 epolarization and a second SCN neuropeptide, gastrin-releasing peptide (GRP), can acutely enhance and

206 hetamine-related transcript (CART), galanin, gastrin-releasing peptide (GRP), neuropeptide Y (NPY), n

207 Gastrin-releasing peptide (GRP), secreted by pulmonary n

208 oxide, vasoactive intestinal peptide (VIP), gastrin-releasing peptide (GRP), substance P, and calcit

209 a subset of spinal interneurons, labeled by gastrin-releasing peptide (Grp), that receive direct syn

210 Exemplified by gastrin-releasing peptide (GRP), these neuropeptides tra

211 ied 5-HT1A as a key receptor in facilitating gastrin-releasing peptide (GRP)-dependent scratching beh

212 PAR-4 was also found on gastrin-releasing peptide (GRP)-positive neurons (pruric

213 ibutions from arginine vasopressin (AVP) and gastrin-releasing peptide (GRP).

214 ry afferent-derived "itch" neurotransmitter, gastrin-releasing peptide (GRP).

215 A gastrin-releasing peptide (GRP)/GRP receptor-mediated au

216 Normally, levels of mammalian bombesin (gastrin-releasing peptide [GRP]) drop postnatally, but t

217 of the mitogenic neuropeptide receptors for gastrin-releasing peptide and arginine vasopressin.

218 ed release of the pruritogenic neuropeptides gastrin-releasing peptide and atrial natriuretic peptide

219 lease of the itch and analgesia transmitters gastrin-releasing peptide and leucine-enkephalin.

220 ropeptides of the bombesin family, including gastrin-releasing peptide and neuromedin B, which are fo

221 ranscription that regulate these parameters: gastrin-releasing peptide and the small conductance, cal

222 ry adenylate cyclase-activating peptide, and gastrin-releasing peptide have shown how these peptides

223 We found that gastrin-releasing peptide is specifically expressed in a

224 r support for a critical role of dorsal horn gastrin-releasing peptide neurons in itch circuits, but

225 e in pain.SIGNIFICANCE STATEMENT Dorsal horn gastrin-releasing peptide neurons serve a well-establish

226 ed by activation of cholinergic and bombesin/gastrin-releasing peptide neurons, acts mainly by releas

227 The gastrin-releasing peptide receptor (BB2r) is overexpress

228 Receptor-targeted agents, such as gastrin-releasing peptide receptor (BB2r)-targeted pepti

229 ed by cells expressing the G-protein-coupled gastrin-releasing peptide receptor (GRP-R) and is curren

230 imilar rationale, radioligands targeting the gastrin-releasing peptide receptor (GRP-R) might offer a

231 However, the limited expression of gastrin-releasing peptide receptor (GRPR) and integrin a

232 We recently introduced the potent gastrin-releasing peptide receptor (GRPR) antagonist (68

233 e treatment of prostate cancer, radiolabeled gastrin-releasing peptide receptor (GRPr) antagonists ha

234 e spinal cord to establish that NK1R and the gastrin-releasing peptide receptor (GRPR) are coexpresse

235 Because overexpression of the gastrin-releasing peptide receptor (GRPR) has been repor

236 MOR1D heterodimerizes with gastrin-releasing peptide receptor (GRPR) in the spinal

237 The overexpression of gastrin-releasing peptide receptor (GRPR) in various tum

238 These NK1R neurons comprise a subset of gastrin-releasing peptide receptor (GRPR) interneurons a

239 The gastrin-releasing peptide receptor (GRPR) is a well-know

240 Although our previous study suggested that gastrin-releasing peptide receptor (GRPR) is an itch-spe

241 The gastrin-releasing peptide receptor (GRPR) is found to be

242 The gastrin-releasing peptide receptor (GRPr) is overexpress

243 The gastrin-releasing peptide receptor (GRPR) is overexpress

244 Gastrin-releasing peptide receptor (GRPR) is overexpress

245 A growing body of evidence suggests that gastrin-releasing peptide receptor (GRPR) might be a val

246 Consistently, ablation of gastrin-releasing peptide receptor (GRPR) neurons, which

247 Ablation of gastrin-releasing peptide receptor (GRPR) or GRPR neuron

248 Here we describe that the gastrin-releasing peptide receptor (GRPR) plays an impor

249 he Trpv1-Cre population, depends on CGRP and gastrin-releasing peptide receptor (GRPR) transmission b

250 -expression of Shh and BBS-cognate receptor (gastrin-releasing peptide receptor (GRPR)).

251 Gastrin-releasing peptide receptor (GRPR), a member of t

252 BBN) is a peptide with high affinity for the gastrin-releasing peptide receptor (GRPr), a receptor th

253 Its receptor, gastrin-releasing peptide receptor (GRPR), is expressed

254 Because expression of the gastrin-releasing peptide receptor (GRPR), somatostatin

255 peptide that binds with high affinity to the gastrin-releasing peptide receptor (GRPR), which is over

256 nd antagonistic pharmacophores targeting the gastrin-releasing peptide receptor (GRPR).

257 g very high selectivity and affinity for the gastrin-releasing peptide receptor (GRPr).

258 ic bombesin receptor antagonist that targets gastrin-releasing peptide receptor (GRPr).

259 Blocking gastrin-releasing peptide receptor and natriuretic pepti

260 is and to use bombesin analogs to target the gastrin-releasing peptide receptor for the diagnosis and

261 icals, such as prostate-specific membrane or gastrin-releasing peptide receptor ligands for the imagi

262 BON cells or BON cells stably expressing the gastrin-releasing peptide receptor treated with either p

263 between an agonist and an antagonist for the gastrin-releasing peptide receptor were found to have ex

264 different neuropeptides for itch, including gastrin-releasing peptide receptor, natriuretic peptide

265 ed independently of neurons that express the gastrin-releasing peptide receptor.

266 Gastrin-releasing peptide receptors (GRP-R) are upregula

267 Gastrin-releasing peptide receptors (GRPrs) are overexpr

268 Gastrin-releasing peptide receptors (GRPRs) are potentia

269 Gastrin-releasing peptide receptors (GRPRs) expressed on

270 ded to understand the expression of PSMA and gastrin-releasing peptide receptors in different types o

271 Peptides such as gastrin-releasing peptide receptors targeting radiopharm

272 Gastrin-releasing peptide receptors, part of the bombesi

273 ic bombesin receptor antagonist that targets gastrin-releasing peptide receptors.

274 ied two TMs (neuron-specific enolase and pro-gastrin-releasing peptide) that differentiate the risk o

275 g neurons respond to histamine and coexpress gastrin-releasing peptide, a peptide involved in itch se

276 uitary adenylate cyclase-activating peptide, gastrin-releasing peptide, and substance P is reviewed.

277 Gastrin, histamine, gastrin-releasing peptide, ghrelin, orexin, and glucocor

278 expressing cells, but a second neuropeptide, gastrin-releasing peptide, still induced strong response

279 ve agonist stimulated scratching behavior by gastrin-releasing peptide- and opioid-dependent mechanis

280 transient receptor potential subtype V1 and gastrin-releasing peptide.

281 e compounds demonstrated that antagonists of gastrin-releasing peptide/neuromedin B receptors (BB/BB)

282 of patients, demonstrating the potential of gastrin-releasing-peptide receptor imaging.

283 n upstream Sp1 binding GC box and downstream gastrin responsive elements.

284 The expression of CaR on gastrin-secreting G cells in the stomach and their share

285 al cilia on endocrine cells, which modulates gastrin secretion and gastric acidity.

286 These studies of nutrient-regulated G-cell gastrin secretion and growth provide definitive evidence

287 a role for endogenous GRP in meal-stimulated gastrin secretion in humans.

288 play a role in the perturbations in acid and gastrin secretion induced by H. pylori.

289 tion of FAK activity, is sufficient to block gastrin-stimulated paxillin phosphorylation, cell motili

290 We show here that gastrin stimulates Shh gene expression and acid-dependen

291 reas the gastrointestinal regulatory peptide gastrin stimulates the growth of neoplastic cells.

292 In gastric cancer cells, gastrin stimulation partially reversed the epigenetic si

293 lls, Rgnef forms a complex with FAK and upon gastrin stimulation, FAK translocates to newly-forming f

294 Gastrin, through p38 activity, also enhanced HuR express

295 nker was used for crosslinking radio-labeled gastrins to membrane proteins from gastrin/PG responsive

296 Two-hour gastrin treatment, known to activate HDC gene expression

297 process that can be suppressed by exogenous gastrin treatment.

298 and particularly in neurons, elevated plasma gastrin, vacuolization in parietal cells, and retinal de

299 Gastrin was measured in blood, tissue, and cell cultures

300 les would also stimulate cell division - the gastrin would stimulate cell division of ECL cells while