ライフサイエンスコーパス: gene expression

1 ygen signaling with epigenetic regulation of gene expression.

2 sents a potential mechanism for coordinating gene expression.

3 ition motifs in gene promoters that regulate gene expression.

4 at govern such heterogeneity at the level of gene expression.

5 gnitude, timing and cell type-specificity of gene expression.

6 and its members are essential for regulating gene expression.

7 d Cas12a to significantly repress endogenous gene expression.

8 imary points of control in the regulation of gene expression.

9 odulate enhancer activity and, consequently, gene expression.

10 se regulatory RNAs perform critical roles in gene expression.

11 ked decreases of both rod- and cone-specific gene expression.

12 which underlie genetic loci known to affect gene expression.

13 anscript levels and analysis of differential gene expression.

14 ed enhanced DNA binding and increased target gene expression.

15 he gastrointestinal tract where it transacts gene expression.

16 super-enhancer regulatory regions to direct gene expression.

17 uals and positively corelated with TNF-alpha gene expression.

18 her cellular processes such as regulation of gene expression.

19 ng factor (CTCF), and modulates AR-dependent gene expression.

20 ing RNA polymerase pause-release to regulate gene expression.

21 failing heart is characterized by changes in gene expression.

22 ptionally silent, is a critical regulator of gene expression.

23 n regulation that mediate the fine-tuning of gene expression.

24 P hubs have less cell-to-cell variability in gene expression.

25 s play an important role in controlling mPFC gene expression.

26 ermined using luciferase reporter assays and gene expression.

27 nd the roles of these decay pathways in KSHV gene expression.

28 t using chemical inhibitors and silencing of gene expression.

29 afficking, including genome organization and gene expression.

30 chromatin play important roles in regulating gene expression.

31 ed mice was associated with enhanced Adora2b gene expression.

32 sting, and direct multiplexed measurement of gene expression.

33 in post-transcriptional steps of chloroplast gene expression.

34 ironment as a novel regulatory framework for gene expression.

35 consensus molecular subtypes (CMS1-4) using gene expression.

36 critical post-transcriptional regulators of gene expression.

37 of diverse DNA-templated processes including gene expression.

38 icochemical properties and drug perturbation gene expressions.

39 cle and is accompanied by dynamic changes in gene expression(1), but the gene regulatory network that

40 Perturbation of gene expression, acquisition of microscopy data and imag

41 s, we investigated whether serotonin-related gene expression across the brain's emotion regulation ci

42 m ID patients have extensive deregulation of gene expression affecting pathways necessary for neuroge

43 Here, we use time series gene expression analyses of the rattlesnake venom gland

44 Gene expression analyses of these plants reveal a trade-

45 Flow cytometric and gene expression analyses revealed that VAT transplantati

46 ial respirometry, enzyme activity assays and gene expression analyses.

47 Here, we perform gene expression analysis and ChIP followed by sequencing

48 advanced speckle tracking echocardiography, gene expression analysis and immunohistological staining

49 Gene expression analysis indicated VCP expression was pa

50 Moreover, gene expression analysis not only revealed correlated ex

51 Gene expression analysis revealed a 4-fold downregulatio

52 Gene expression analysis revealed that the expression of

53 Most studies of computational methods for gene expression analysis use simulated data to evaluate

54 By gene expression analysis, we identified two molecules th

55 Through a combination of proteomics and gene expression analysis, we identify enzymes involved i

56 y injury was evaluated by histopathology and gene expression analysis.

57 14, 42, and 84 and processed for microarray gene expression analysis.

58 d type I and type II-that differ in terms of gene expression, anatomy and function.

59 causal pathways between AD and T2DM, and 754 gene expression and 101 gene methylation nodes that were

60 is demonstrated developmental differences in gene expression and accessible chromatin between progeni

61 e describe a method to correlate VAFRNA with gene expression and assess its ability to identify genet

62 heterogeneity encoding spatial gradients of gene expression and defining anatomical location in a co

63 e loss of H4K20me3 genome wide, dysregulated gene expression and delayed ES cell differentiation.

64 By investigation of the changes in gene expression and functional screening using an in vit

65 hort tandem repeats that are associated with gene expression and human traits.

66 vity in the regulation of RSC proliferation, gene expression and in the repression of endogenous retr

67 f contractile proteins such as higher atrial gene expression and lower MYH7/MYH6 ratio correlated wit

68 taset encompassing physiological parameters, gene expression and metabolite profiling on plants grown

69 knowledge on molecular relationships between gene expression and minerals.

70 e plasma membrane to modulate BDNF-dependent gene expression and neuronal dendritic growth mediated b

71 egions, but there are notable differences in gene expression and proportions between foveal and perip

72 t studies have shown that the integration of gene expression and protein interaction data improves th

73 se inhibitor RTA405 enhanced SMAD3-regulated gene expression and reduced growth of HCC cells in cultu

74 lius were identified, and correlation of the gene expression and the contents of flavonoid metabolite

75 vity dynamics that correlate with changes in gene expression, and find that the strongest correlation

76 509 does inhibit viral DNA replication, late gene expression, and virus production.

77 besity on microglial activation and IL-1beta gene expression, and visualization of hippocampal microg

78 Genome-wide DNA methylation and gene expression are commonly altered in pediatric acute

79 Mitochondrial metabolism and gene expression are highly regulated to accommodate thes

80 viral antigens as well as intratumoral oHSV gene expression are important in oHSV-mediated GBM thera

81 prognostic performance, and that most of the gene expressions are weakly correlated imaging features.

82 t epigenetic mechanisms, and their effect on gene expression, are a major conduit through which OA ge

83 eparate sample, we investigated the neuronal gene expression associated with CUD by using RNA sequenc

84 presses HIV-1-driven aberrant cancer-related gene expression at the integration site.

85 igh-quality wheat genome sequence, alongside gene expression atlases, variation datasets and sequence

86 Using a machine learning approach, we built gene expression-based models to predict drug sensitivity

87 ation, which lead to the improved downstream gene expression-based prediction of disease outcome.

88 e disequilibrium (LD) and the correlation of gene expression between tissues.

89 and luciferase reporter assays; we measured gene expression, binding activity, cell migration and in

90 cle biopsies, while our two late DUX4 target gene expression biomarkers associate with macroscopic in

91 linoleate/oleate downregulated inflammatory gene expression, but IDL more effectively upregulated th

92 og-sensitive CDK12 reduces DNA damage repair gene expression, but selective inhibition of endogenous

93 ation (H3K27me3) are linked to repression of gene expression, but the functions of repressive histone

94 has been extensively linked to regulation of gene expression, but the mechanisms behind this directed

95 esults demonstrate that holo-WhiB1 regulates gene expression by a non-canonical mechanism relative to

96 Polycomb group (PcG) proteins silence gene expression by chemically and physically modifying c

97 criptomic responses using Capped Analysis of Gene Expression (CAGE).

98 Gene expression can be activated or suppressed using CRI

99 Stochastic pulsing of gene expression can generate phenotypic diversity in a g

100 e provide valuable information about dynamic gene expression changes during cambium-driven root growt

101 r cardiomyocyte morphology and function: (1) Gene expression changes of contractile proteins such as

102 tic tissue from eye bank donors to probe how gene expression changes precede disease; and (iii) The a

103 We demonstrate gene expression changes that significantly impact pathwa

104 llular integrity, migration, and genome-wide gene expression changes were examined in 16HBE14o- singl

105 cterize mutations, karyotype alterations and gene expression changes, and dissect the associated mole

106 rom naive and EAU mice were sorted and their gene expression compared by RNA-Seq.

107 omologs, MLL3/4, cause only minor changes in gene expression compared with whole-gene deletions for t

108 Gene expression correlates inversely with distance to nu

109 Size-scaled gene expression could cause an increasing ratio of activ

110 alization analysis to identify loci at which gene expression could potentially explain breast cancer

111 understanding of the molecular basis of HbF gene expression, coupled with the ability to precisely t

112 tory networks are typically constructed from gene expression data acquired following genetic perturba

113 ance spike seed setting and grain size using gene expression data and were validated in three bi-pare

114 We compress gene expression data from three large datasets consistin

115 g a new dataset of 30,612 spatially resolved gene expression data matched to histopathology images fr

116 lity of tuxnet when using different types of gene expression data to infer networks and its accessibi

117 ments, and annotated this model with matched gene expression data.

118 ct downstream pathways that best explain the gene expression data.

119 sulted in differential changes of core clock gene expression, demonstrating an exercise and clock int

120 We demonstrate that light-induced transient gene expression depends on MED12, and is accompanied by

121 1alpha- and HIF2alpha-mediated regulation of gene expression did not explain most of the effects.

122 numerous studies examining how CodY controls gene expression directly or indirectly, virtually nothin

123 Our likelihood-based approach models the gene expression distribution of debris and cell types, w

124 dy investigated the prevalence of a range of gene expression distributions in three different tumor t

125 Gene expression during dedifferentiation was predominant

126 Chromatin regulates spatiotemporal gene expression during neurodevelopment, but it also med

127 sticity of cell types and cell-type-specific gene expression during organ evolution including express

128 that has investigated genome-wide changes in gene expression during the normal physiological fasting-

129 -resolved census of neutrophil diversity and gene expression dynamics in the mouse blood and ischemic

130 affords bidirectional, graded modulation of gene expression enabled by tiling the promoter regions o

131 rios in high-dimensional data, such as GWAS, gene expression, eQTL and structural/functional neuroima

132 oved accuracy, precision, and reliability of gene expression estimation, which lead to the improved d

133 the molecular mechanisms and determinants of gene expression evolution in natural populations, we ana

134 tion on molecular changes in cancer-specific gene expression facilitates efficient targeted therapies

135 ed endoplasmic reticulum (ER) stress related gene expressions, fasting glucose levels, insulin sensit

136 ting in vitro cytokine secretion and in vivo gene expression for effectors associated with inflammati

137 CD29 also marked T cells with cytotoxic gene expression from different tissues in single-cell RN

138 This data was integrated with gene expression from E2F2 knockout tumors in an MMTV-Neu

139 arning algorithm for the prediction of local gene expression from haematoxylin-and-eosin-stained hist

140 Targeted gene expression (GE) profiling of 184 genes using nCount

141 hylation plays a critical role in regulating gene expression, genomic stability, and cell fate commit

142 sociations between the genetically regulated gene expression (GReX) of ZC3H12B and Alzheimer dementia

143 ses, its role in physiological processes and gene expression has remained elusive.

144 Our findings include that gene expressions have slightly better prognostic perform

145 important to control networks of coordinated gene expression; however, much remains to be understood

146 g with glia (IBA1, GFAP) were examined using gene expression, immunofluorescence, and in silico model

147 ibutes to transcript diversity and modulates gene expression in a dynamic, cell type-specific manner.

148 ing cooperate to promote the dorsal-specific gene expression in amphioxus gastrula.

149 of identified CpGs, association of DNAm with gene expression in blood was assessed.

150 ings provide insights into how GLI1 controls gene expression in cancer cells and may inform approache

151 Differential gene expression in cells from these niches allow monitor

152 ain and regional signatures of AMPAR subunit gene expression in healthy human brains as well as the t

153 However, longitudinal analyses of gene expression in healthy individuals-especially with r

154 ) as a novel regulator of fetal gamma-globin gene expression in human cells by repressing BCL11A tran

155 ompletely reversed elevated pro-inflammatory gene expression in macrophages.

156 ism that allows the cell to rapidly modulate gene expression in order to provide flexibility and adap

157 synthetic riboswitches were used to regulate gene expression in plastids, but the application of synt

158 emonstrated that these LTR12C elements drive gene expression in primary CD4+ T cells.

159 was used to assess changes in ET-1 mediated gene expression in primary RGCs, which revealed that 23

160 tors in prokaryotes and function by altering gene expression in response to environmental stimuli.

161 creased lipid deposition and the atherogenic gene expression in the arterial wall and aortic sinus in

162 oritize variants in terms of their impact on gene expression in the brain.

163 was associated with replicable differential gene expression in the DLPFC.

164 sm of regulation of secondary metabolism and gene expression in the glandular trichomes of N. tabacum

165 sm but leads to a reprogramming of circadian gene expression in the liver in analogy to what is obser

166 causes substantial and transient changes in gene expression in the livers of both mouse strains.

167 runcated transcription factor that activates gene expression in the nucleus.

168 cocaine triggers reprogramming in circadian gene expression in the striatum, an area involved in psy

169 Using ZipSeq, we mapped gene expression in three settings: in vitro wound healin

170 er, RNA sequencing analysis revealed altered gene expression in Tph1 deficient ILC2s including induci

171 m by which satellite repeats regulate global gene expression in trans via piRNA-mediated gene silenci

172 molecules and discuss their effects on c-MYC gene expression in vitro and in vivo.

173 We observed widespread gene expression in, central and peripheral nervous syste

174 r kappa-B ligand, periostin, and peroxidasin gene expressions in peri-implant mucosa were noted withi

175 These novel inhibitors suppress inflammatory gene expression induced by EP2 receptor activation in a

176 Gene expression is a key determinant of cellular respons

177 The regulation of gene expression is a result of a complex interplay betwe

178 Gene expression is also regulated by long noncoding RNAs

179 The regulation of gene expression is central to many biological processes.

180 Control of gene expression is dictated by cell-type specific regula

181 decades, knowledge of mechanisms that induce gene expression is limited.

182 glial-enriched miRNA that controls neuronal gene expression is regulated by antipsychotics.

183 An attractive approach to reduce gene expression is via the use of antisense oligonucleot

184 Besides regulation of gene expression, its crosstalk with protein phosphorylat

185 ies and poor understanding of how genetic or gene expression landscapes connect to specific CIN mecha

186 genes at 3 hpi and that repression of alpha gene expression late in infection is mediated by prolong

187 microbiota and how this is regulated at the gene expression level are critical questions.

188 showed an overall positive correlation with gene expression level as well as prominent associations

189 n = 135,458 cases, n = 344,901 controls) and gene expression levels from 21 tissue datasets (brain; b

190 ble to respond to exogenous auxin and AtDRO1 gene expression levels in root tips were unaffected by t

191 ses also revealed significant alterations in gene expression levels of key enzymatic regulators of bi

192 dividual cells to fluctuate substantially in gene expression levels over time.

193 esting was used to measure lung function and gene expression levels were measured using the Nanostrin

194 ination is common and might in turn regulate gene expression levels.

195 ans to reprogram chromatin state and to hone gene expression levels.

196 This process is characterized by structural, gene expression, metabolic, and functional specializatio

197 We downloaded data of gene expression microarrays (GSE20347, GSE38129) and gen

198 The metabolic state of an organism instructs gene expression modalities, leading to changes in comple

199 matergic projection neurons distinguished by gene expression, morphology, distribution, and input-out

200 The control of gene expression noise is important for improving drug tr

201 nonequilibrium models is in a trade-off with gene-expression noise, predicting bursty dynamics-an exp

202 beta-oxidation of fatty acids and stimulated gene expression of acyl-CoA dehydrogenases in the liver.

203 methylation microarrays (GSE52826) from the Gene Expression Omnibus (GEO) database.

204 AnxA8 gene expression, on the other hand, remained unaltered u

205 c acid drug payload for sustained, long-term gene expression or silencing.

206 nlike the bulk measurements that average the gene expressions over the individual cells, gene measure

207 constructs, CYP2B11-H3 showed markedly lower gene expression (over 70%) compared to CYP2B11-H1 while

208 g their cis- and trans-regulatory effects on gene expression (particularly, transcription) are reveal

209 re, we demonstrate that the NRF2 antioxidant gene expression pathway is suppressed in biopsies obtain

210 The gene expression pattern in the cryptal mesenchymal cells

211 Further, we demonstrate that basal gene expression patterns are predictive of changes in FO

212 examination of mRNA transcript abundance and gene expression patterns in the internal organs of decea

213 ther, our analyses provide insights into the gene expression patterns of SARS-CoV-2-reactive CD4(+) T

214 We investigated the gene expression patterns of skeletal muscle cells using

215 Moreover, they demonstrate that gene expression patterns reflecting the cellular hierarc

216 interferes with memory consolidation, alters gene expression patterns, and disrupts spine morphology.

217 P-1 cells (THP1-MPhi) have largely conserved gene expression patterns.

218 Recent work has shown that gene-expression patterns within the mTEC compartment are

219 onged treatment, modulated rejection-related gene-expression patterns.

220 Small RNAs (sRNAs) regulate gene expression, play important roles in epigenetic path

221 Hfq regulates bacterial gene expression post-transcriptionally by binding small

222 n of protein functions involves differential gene expressions, post-translation modifications, and si

223 t association directions for the methylation-gene expression-PrCa pathway.

224 Training on both genomes improves gene expression prediction accuracy on held out and vari

225 Global gene expression profile of stem cells reveals significan

226 The HBV-induced gene expression profile was similar to that induced by t

227 A specific gene expression profile, referred to as ECM3 (Extracellu

228 e has examined social status-dependent brain gene expression profiles across vertebrates, yet social

229 B cell responses and the promotion of T(h)1 gene expression profiles in GC T(fh) cells.

230 hs of life, and measured DNA methylation and gene expression profiles in upper airway mucosal cells a

231 generation RNA sequencing to investigate the gene expression profiles intrinsic to this disease.

232 The gene expression profiles of invading microtumors were an

233 Here, we tested the hypothesis that gene expression profiles of protein-coding genes express

234 Immunophenotypic and gene expression profiles revealed a unique spectrum of m

235 These datasets delineate gene expression profiles spanning key differentiation ev

236 Coupling pMEI genotypes with gene expression profiles, we identify pMEI-associated ex

237 entify biomarker genes for lung cancer using gene expression profiles.

238 present a minority of patients studied using gene expression profiles.

239 nisms including body images and whole-genome gene expression profiles.

240 ofiling to catalog DA neurons based on their gene expression profiles.

241 The gene expression profiling analysis showed that PRLT2/89-

242 Here, using single-cell gene expression profiling and anatomical circuit analyse

243 linary epidemiological, cell biological, and gene expression profiling approaches, we report here mul

244 Surface phenotype and NanoString gene expression profiling indicated the closest steady-s

245 Gene expression profiling of the isolated cell protrusio

246 In these cases, gene expression profiling showed diminished expression o

247 of next-generation sequencing technologies, gene expression profiling using RNA-seq has increased th

248 R cell effector molecule through single-cell gene expression profiling.

249 lineage-specific genes while restricting the gene expression program of alternative Th fates.

250 ntly reported that oncogenic KRAS promotes a gene expression program of de novo lipogenesis in non-sm

251 tablish and reinforce the cell-type-specific gene-expression program; the ensemble of core TFs and th

252 ormation and lineage differentiation involve gene expression programs orchestrated by transcription f

253 detained intron splicing to tune system-wide gene expression, providing a means to couple nutrient co

254 To facilitate gene expression queries across different gene annotation

255 echanism to synchronize the phases of target gene expression regulated by the same deadenylases.

256 Our data emphasize the importance of gene expression regulation through the dynamic AGO2-RNA

257 ncluding transcriptional rewiring of nuclear gene expression, return to levels, such as, or even high

258 Analysis of gene expression revealed significant upregulation of nit

259 ear genes involved with global regulation of gene expression (SATB1) and the estrogen receptor alpha

260 increased inflammation and fibrosis related gene expression (Serpine 1, Plau, and Timp1) in Mus as c

261 low tumor mutational burden/T cell-inflamed gene expression signature (GES) or high immunosuppressiv

262 ccRCC shows a gene expression signature consistent with adipogenesis,

263 ssion of hundreds of genes in the basal-like gene expression signature, which were associated with po

264 Moreover, the biomarker gene expression signatures yielded leads for possible ne

265 specific transcriptional perturbations from gene expression signatures.

266 Currently, prognostic gene-expression signatures do not exist for all cancer t

267 such as enhancers, but regions that repress gene expression-silencers-have not been systematically s

268 ach identifying circular trajectories in the gene expression space.

269 long with increased body temperature and BAT gene expression, specifically Cox8b.

270 We showed that H19X regulates DDIT4L gene expression, specifically interacting with a region

271 btelomeric domains that produces a heritable gene expression state that enables resistance to stress.

272 We demonstrate a novel viral gene expression strategy to target cells with specific m

273 Despite multiple gene expression studies becoming available, the limited

274 In gene expression studies, SHP inhibited miR-210 expressio

275 We performed a gene expression study using RNA sequencing of CNON cells

276 Nevertheless, this mutant can induce early gene expression, suggesting a possible defect at the lev

277 at it is required for Pnr- and Srp-dependent gene expression, suggesting general GATA cofactor functi

278 ent, OMT activity in crude extracts, and OMT gene expression supported physiological roles for NnOMT1

279 variants in a known epigenetic regulator of gene expression: ten-eleven translocation methylcytosine

280 etylases (HDACs) are important regulators of gene expression that are aberrantly regulated in several

281 h as cortical thickness, myelin content, and gene expression that change along the posterior-anterior

282 Resulting changes in muscle-specific gene expression that take place in dystrophin's absence

283 ed upstream regulators can ensure correlated gene expression, the selective advantage of maintaining

284 ane-associated TNF and dampened inflammatory gene expression through reverse signaling.

285 by profound changes in the association, from gene expression to behavior.

286 er of differentiation (CD)138-selected tumor gene expression to control for tumor burden, we identifi

287 This amplification-mediated gene expression tuning (AMGET) occurs on timescales that

288 that inserted promoters have a wide range of gene-expression variability related to their location.

289 Gene expression was analyzed using RNA-Seq and RT-PCR.

290 Downregulation of EP300 gene expression was associated with higher anti-tumor im

291 Accordingly, ChREBP target gene expression was rescued by re-expressing WT but not

292 The increase in CRF gene expression was similar across all groups; however,

293 Transient changes in gene expression were identified after both infection and

294 Most VEGF-induced changes in gene expression were not reversed by anti-VEGF.

295 moter polymorphism might lead to altered DRB gene expression, which could possibly affect the TLR-tri

296 hat alpha2-Na/K ATPase loss alters metabolic gene expression with consequent serine and glycine eleva

297 lant cells orchestrate root morphogenesis to gene expression with the STOP1-ALMT1 module.

298 ice brain is able to induce Ca(2+)-dependent gene expression without any mechanical damage in the bra

299 iption is the first step of most analyses of gene expression, yet the quantitative biases it introduc

300 e of DNA or RNA which can enhance or repress gene expression, yet the underlying molecular mechanism