ライフサイエンスコーパス: gene involved in

1 Genes involved in 3'-splice site recognition during mRNA

2 ied significant changes in the expression of genes involved in 4Fe-4S center binding, Fe-S center syn

3 Thus, we identify key genes involved in a pathway within DCs that is exploited

4 bmr12 had increased transcript abundance of genes involved in (a)biotic stress response, gibberellic

5 tolerance in C-76 through activation of key genes involved in ABA and sucrose metabolic pathways.

6 e ompR was induced at alkaline pH to repress genes involved in acid tolerance and virulence factor pr

7 lic proteins, and non-synonymous variants in genes involved in adhesion, iron acquisition, and endoto

8 r mitochondrial pathways and determined that genes involved in aerobic respiration or mitochondrial D

9 As expected, IFN-gamma induced genes involved in Ag presentation and antimicrobial defe

10 llus subtilis using auxotrophic markers, the genes involved in alanine metabolism have not been chara

11 alysis showed a coordinated up-regulation of genes involved in all stages of protein biosynthesis and

12 of the glucagon receptor (GCGR), PEPCK, and genes involved in amino acid metabolism and urea product

13 f activating EGR mediated transactivation of genes involved in angiogenesis and cell proliferation.

14 ur data show that DEWAX negatively regulates genes involved in anthocyanin biosynthesis.

15 There is enrichment for genes involved in anthropometric traits, hindbrain devel

16 urther identified an extensive repertoire of genes involved in antibiotic resistance and detoxificati

17 ells mainly brought to light upregulation of genes involved in antigen presentation and T cell activa

18 ast metabolic bypass line to determine which genes involved in apicoplast carbon metabolism are requi

19 itotic cell division but an up-regulation of genes involved in apoptosis and stress response to micro

20 Elevated proportion of down-regulated genes involved in apoptosis, NFKB signaling as well as s

21 hythmicity resulting from oscillation in the genes involved in AS and APA.

22 The genes involved in assembly and export of HPS are largely

23 females unveiled a deregulated expression of genes involved in asthma pathogenesis, tissue remodeling

24 hich regulate the expression of a network of genes involved in autophagy and lysosomal biogenesis, we

25 utants have led to the identification of key genes involved in auxin biosynthesis, transport, and sig

26 revealed that the dataset was enriched with genes involved in auxin response and signaling; and in a

27 n metabolism, as evident by misregulation of genes involved in auxin transport and signaling as well

28 -insensitive complex-2 of mTOR (mTORC2), and genes involved in axon growth, whereas genes related to

29 corresponding to the abnormal expression of genes involved in axon navigation.

30 cipants exhibited downregulation of critical genes involved in B cell function (PAX5, CD79A, CD22, an

31 rmicutes ratios and an elevated abundance of genes involved in bacterial growth and division.

32 positively associated with the expression of genes involved in BCAA catabolism, in conjunction with a

33 g of bile acids, regulates the expression of genes involved in bile acid, fat, sugar, and amino acid

34 Genes involved in both longevity and cardiovascular dise

35 eads to the enhanced translation of multiple genes involved in Ca(2+) regulation and to increased Ca(

36 der) gut microbiome samples were enriched in genes involved in carbohydrate metabolism and cellulose

37 Variants were enriched in genes involved in carbohydrate metabolism, and phenotypi

38 nalysis of non-CAD-associated loci implicate genes involved in cardiac development (MYOZ1, SYNPO2L),

39 Genes involved in carotene production and oxidative stre

40 The mutated genes involved in cavefish vestigial eye formation have

41 t 12a (PPP1R12A), an important developmental gene involved in cell migration, adhesion, and morphogen

42 is demonstrates down-regulated expression of genes involved in cell adhesion and markers of deciduali

43 steroid action is positively associated with genes involved in cell differentiation and cell-wall bio

44 five dogs, with 44% of the integrations near genes involved in cell growth.

45 y triggered changes in the expression of the genes involved in cell lesion containment through a defi

46 se include known miR-133b targets as well as genes involved in cell proliferation and fibrosis.

47 described as a transcriptional activator of genes involved in cell proliferation and survival.

48 tumorigenic mice had increased expression of genes involved in cell proliferation, immune responses,

49 Interestingly, fisetin also activates genes involved in cell proliferation.

50 modimers regulated the transcription of some genes involved in cell proliferation.

51 Moreover, genes involved in cell wall and cuticle biosynthesis are

52 dings, transcriptomics identified changes in genes involved in cell wall modifications.

53 riment, turned out to have a high content of genes involved in cell wall polysaccharides decompositio

54 ork were experimentally shown to up-regulate genes involved in cell-cycle and transcriptional regulat

55 nistically converge, as they all dysregulate genes involved in cell-cycle control and progenitor cell

56 egulates the expression of a large number of genes involved in cellular growth, proliferation and met

57 imaging to screen an siRNA library targeting genes involved in cellular trafficking networks, the fir

58 Furthermore, we identify genes involved in cellular transport, including calcium

59 Furthermore, genes involved in central and energy metabolism and ribo

60 ylated regions in N-ERD macrophages included genes involved in chemokine signaling and acylcarnitine

61 two protochlorophyllide oxidoreductase (POR) genes involved in chlorophyll biosynthesis is noteworthy

62 In addition, the upregulation by heat of genes involved in chlorophyll catabolism and chloroplast

63 in large macrophages, with up-regulation of genes involved in cholesterol metabolism, scavenger rece

64 development by inhibiting the expression of genes involved in chondrocyte hypertrophy and osteogenes

65 risomy 8, and most cases harbor mutations in genes involved in chromatin modification or the JAK/STAT

66 Further research has examined mutations in genes involved in chromosome remodelling (for example, P

67 The first comprises genes involved in chromosome segregation and stability (

68 s also upregulated expression of PER1 (a key gene involved in circadian control) in agreement with sl

69 ified and validated multiple novel candidate genes involved in circadian period determination in the

70 The regulation of guard cell genes involved in controlling stomatal movements was als

71 is to identify key vascular pathways and top genes involved in CRS.

72 The top DMP was located in SLC7A11A, a gene involved in cystine/glutamate transport and the bio

73 to infect humans, demonstrated that variant genes involved in cytoadherence were dependent on the sp

74 rally localized CELF1 protein, with affected genes involved in cytoskeleton dynamics, membrane dynami

75 and further implicate mutation of additional genes involved in de novo NAD synthesis as potential cau

76 drocarbon receptor) drives the expression of genes involved in detoxification pathways in cells expos

77 lyses of DM promoters show an enrichment for genes involved in differentiation and development.

78 cids to identify target molecules or silence genes involved in disease pathways.

79 13 single or multiple evolutionary conserved genes involved in distinct genome maintenance processes

80 study of Huntington disease (HD) implicated genes involved in DNA maintenance processes as modifiers

81 e, we show that an extensive derepression of genes involved in DNA metabolism and cell cycle-related

82 Mutations in genes involved in DNA methylation (DNAme; for example, T

83 st association between the DUF328 family and genes involved in DNA recombination and the oxidative st

84 located in human leukocyte antigen genes and genes involved in drug metabolism pathways.

85 etastatic PCa, we identified mutations in 31 genes involved in DSB response and repair.

86 ine-mediated inhibition of the expression of genes involved in early KC differentiation, including ke

87 ghted the overrepresentation of dysregulated genes involved in ECM organization, or being connected t

88 Moreover we identify multiple genes involved in endocytosis and intracellular membrane

89 tant S. cerevisiae clones carry mutations in genes involved in Endoplasmic Reticulum (ER)-based lipid

90 Specifically, genes involved in energy production required for extrace

91 n MF lines showed that SATB1 upregulated the genes involved in eosinophil recruitment, including sign

92 Extracellular matrix genes involved in epithelial-mesenchymal transition are

93 transcription factor that globally activates genes involved in erythroid cell development.

94 RNA exchange (CROSS-FIRE) we uncover various genes involved in EV subtype biogenesis that play a regu

95 and strongly enriched in glycosyltransferase genes involved in exopolysaccharide synthesis.

96 rs67327215, located within RGS6 (a gene involved in fatty acid synthesis), and two other SN

97 y was associated with elevated expression of genes involved in fatty acid catabolism.

98 ies reveal that BCL6 regulates a core set of genes involved in fatty acid oxidation and mitochondrial

99 ic level through the regulation of important genes involved in fatty acid regulation, energy producti

100 In addition, ERRgamma was found to suppress genes involved in fibroblast activation in hearts of pn-

101 noid metabolites revealed potential critical genes involved in flavonoids biosynthesis.

102 rapid-flowering mutant phenotype, a range of genes involved in floral induction and flower developmen

103 ic transcriptional programme, which includes genes involved in focal adhesion and extracellular matri

104 e consistent with Ybx1-mediated promotion of genes involved in forebrain specification, cell prolifer

105 Moreover, this work focused on genes involved in gametogenesis and sexual development.

106 own that the expression patterns of numerous genes involved in gemcitabine sensitivity are down regul

107 One of four genes involved in generalized abiotic stress tolerance i

108 c profiling revealed deregulation of various genes involved in genome stability but were not directly

109 egions highlight potentially causal roles of genes involved in germ layer differentiation (WDHD1, DNM

110 s of the hippocampus showed dysregulation of genes involved in glucocorticoid signaling pathway (HPA

111 Among genes involved in glucose metabolism, hexokinase domain

112 or even opposite expression patterns of the genes involved in glycolysis and the synthesis of FAs, 2

113 that PHF19 loss promotes deregulation of key genes involved in growth, metastasis, invasion, and of f

114 rare genetic diseases caused by mutations in genes involved in heme biosynthesis.

115 Examination of the promoter regions of all genes involved in heparin/heparan sulfate assembly uncov

116 suggests that mutation to several additional genes involved in homologous recombination may also have

117 s Lineage-Specific (LS) regions that contain genes involved in host adaptation.

118 Genes involved in host colonization and immune system ev

119 Fungal functional genes involved in hydrolysis of organic matter increased

120 Expression levels of GSDMB correlated with genes involved in IFN signaling, MHC class I antigen pre

121 o associated with increased abundance of the genes involved in imidazole propionate biosynthesis from

122 l differential editing sites are enriched in genes involved in immune and viral processes.

123 ic proliferation of NSCs and upregulation of genes involved in immune processes.

124 inhibitor that activates expression of many genes involved in immune system pathways, its effects on

125 Transient modulation of the genes involved in immunity, without exerting a permanent

126 ated response signature with upregulation of genes involved in immunosuppression.

127 One approach to identifying genes involved in infertility is to study subjects with

128 ere relate to altered expression of critical genes involved in inflammation and cancer-related proces

129 therapy because of their ability to modulate genes involved in inflammation, cell proliferation or di

130 nd are associated with altered expression of genes involved in inflammation, extracellular matrix, an

131 e is required to strongly upregulate several genes involved in inflammatory responses (e.g., Saa4), c

132 SREBP targets, and induced the expression of genes involved in initial steps of mitochondrial steroid

133 inal infection, and mice deficient in select genes involved in innate immune responses are susceptibl

134 Cluster I was highly enriched for genes involved in innate immunity and apoptosis, and mos

135 co-expressed in nasal epithelial cells with genes involved in innate immunity, highlighting the cell

136 ed in vitro to tacrolimus, and validation of genes involved in insulin signaling and glucose metaboli

137 genes isolates, including putative virulence genes involved in iron acquisition (n = 67), fimbriae/pi

138 kines, through p63, also regulate additional genes involved in KC differentiation, including CHAC-1,

139 tiation and epigenetically silences critical genes involved in keratinocyte differentiation.

140 tment with KE reprogrammed the expression of genes involved in ketone body utilization and normalized

141 Our integrated analysis illustrated the hub genes involved in KIRC tumorigenesis, shedding light on

142 Abundances of functional genes involved in labile C degradation decreased while t

143 ion to changes in chromatin accessibility of genes involved in lateral sclerosis, basal transcription

144 enous cholesterol reporter and identify >100 genes involved in LDL-cholesterol import.

145 ynthase FASN-1, anti-microbial peptides, and genes involved in lethargus states.

146 ograft models, through downregulation of key genes involved in leukemogenesis.

147 A chromosome Pv03 dirigent-like gene, involved in lignin biosynthesis, showed a base-pai

148 ions and metabolic capacity, and to identify genes involved in lignocellulose degradation.

149 dition, we observed changes in expression of genes involved in lipid metabolism and calcium handling

150 the GFRAL-RET pathway induces expression of genes involved in lipid metabolism in adipose tissues, a

151 enriched genes, C57BL/6J mice expressed more genes involved in lipid metabolism than BALB/cJ mice.

152 target genes showed upregulation of several genes involved in lipid uptake, transport, and storage a

153 ith their respective promoters to upregulate genes involved in local protein translation in synaptic

154 red perinatal and/or postnatal expression of genes involved in lung development along with an impaire

155 mediated regenerative program regulating 19 genes involved in lung endothelial cell survival, angiog

156 ng vascular remodeling, pericytes upregulate genes involved in mature pericyte cell function, togethe

157 ally methylated regions (DMRs) were found in genes involved in metabolic pathways, carbon metabolism,

158 iptomal analysis revealed that expression of genes involved in metabolic processes was altered in SXR

159 that the BAP complex regulates expression of genes involved in metabolism at least partially independ

160 cytosis in microglia in vitro and identified genes involved in metabolism, chromatin remodeling, and

161 Furthermore, genes involved in metabolism, coagulation, and adaptive

162 ited significant and early downregulation of genes involved in metabolism, coagulation, hormone synth

163 decreased the expression of a large group of genes involved in metabolism, particularly proteolysis.

164 ith multiple nuclear receptors that regulate genes involved in metabolism.

165 deling genes (lytN, ddh), the urease operon, genes involved in metal transport (feoA, mntH, sirA), an

166 e gamma-synthase, regulate the expression of genes involved in methionine metabolism in response to S

167 genes included several Nme genes and several genes involved in methylation-dependent chromatin silenc

168 hat resulted from differential expression of genes involved in microtubules, cytoskeleton linkages, a

169 compartment after VEGF inhibition, including genes involved in migration, chemotaxis, and cell adhesi

170 tochondrial density and expression levels of genes involved in mitochondrial biogenesis and dynamics

171 altering expression of many genes including genes involved in mitochondrial function and electron tr

172 l death through regulating the expression of genes involved in mitochondrial functions.

173 es localizing to the mitochondria, including genes involved in mitochondrial translation.

174 on caused an overwhelming down-regulation of genes involved in mitotic cell division but an up-regula

175 ressed genes in diploid sporophytes included genes involved in morphogenesis and halogen metabolism.

176 highly enriched at enhancers associated with genes involved in multiple profibrotic pathways, and bro

177 icate that LRRK2 modulates the expression of genes involved in murine immune cell chemotaxis.

178 myotubes, with an enrichment of upregulated genes involved in muscle development.

179 iber number, fiber type and misregulation of genes involved in muscle differentiation.

180 Genes involved in N metabolism, N transporters, and NODU

181 es in expression for a significant number of genes involved in N signalling and metabolism.

182 tered more than two-fold with age, including genes involved in nerve function, signaling, metabolism,

183 e samples from the TCGA database, focused on genes involved in neural functions.

184 evelopment by manipulating Hh and downstream genes involved in neural pattern and cell identity.

185 Identifying modifiers of dosage-sensitive genes involved in neurodegenerative disorders is imperat

186 y expressed miRNA in the brain and regulates genes involved in neuronal function.

187 ctivate or repress transcription of specific genes involved in nickel homeostasis and acid adaptation

188 ls in blood as well as expression changes of genes involved in NK-cell function in skin lesions of pa

189 , DRT111 controls expression and splicing of genes involved in osmotic-stress and ABA responses, ligh

190 nd MAPK activation, as well as expression of genes involved in other immune-related signaling pathway

191 port that inhibiting expression of essential genes involved in outer membrane biogenesis can also tri

192 er increased with ambient N deposition while genes involved in oxidation of organic matter decreased.

193 e latter was evidenced by down-regulation of genes involved in oxidative phosphorylation and by impai

194 ith clinical outcomes and identified nuclear genes involved in oxidative phosphorylation and glycolys

195 We compare the structure of the genome and genes involved in penicillin synthesis with those in two

196 expression of Salmonella virulence factors, genes involved in pertussis, and antimicrobial resistanc

197 (INSeq) could be used to identify bacterial genes involved in phage binding.

198 al and computational approaches predict that genes involved in phage lytic function are preferentiall

199 led a novel regulatory pathway that controls genes involved in phosphatidylcholine and fatty acid uti

200 Similar to land plants, proteins genes involved in photosynthetic metabolism have lower s

201 re lacking in Arabidopsis, and the number of genes involved in pollen signaling is significantly redu

202 During a screen for genes involved in presynaptic homeostatic synaptic plast

203 scarcity invokes differential expression of genes involved in processing of most if not all elements

204 ude of this process through the induction of genes involved in proliferation and glycolytic metabolis

205 The proteins encoded by important genes involved in promoting infection included domains g

206 Cluster II was highly enriched for genes involved in protein folding, and most transcript l

207 Genes involved in protein synthesis and DNA damage were

208 epithelium, B. fragilis upregulated numerous genes involved in protein synthesis, indicating that bac

209 isms for protein turnover, and disruption of genes involved in proteostasis is a common cause of neur

210 ed Gadd45b knockdown decreases expression of genes involved in psychostimulant addiction, blocks indu

211 Genes involved in purine synthesis and ribosome structur

212 ess a tissue-adaptation signature, including genes involved in regulating and interacting with extrac

213 oth increased and decreased transcription of genes involved in regulating multiple metabolic pathways

214 AT2 should be considered a new LPS-inducible gene involved in regulation of protein O-GlcNAcylation,

215 ent analysis suggested a role for additional genes involved in renal function.

216 obiome and her mating status: transcripts of genes involved in reproduction and genes with neuronal f

217 Similarly, proteins encoded by genes involved in resistance included those carrying dom

218 pathways and lead to overexpression of HSPs genes, involved in resistance to cancer and Alzheimer's,

219 An increasing number of genes involved in RGC intrinsic signaling have been foun

220 nce of a hub-like structure that colocalizes genes involved in ribosome biogenesis.

221 Genes involved in RNA regulatory mechanisms were affecte

222 A line candidate approach, we identified one gene involved in root growth control and characterized i

223 th phenotypic observations, transcription of genes involved in SA and JA/ET pathways was antagonistic

224 H3K4me3 enrichment and expression of defence genes involved in SA- and Pip-mediated defence pathways.

225 Expression analyses of 23 genes involved in salinity stress revealed that the expr

226 comprehensive resource for identification of genes involved in seasonal leaf senescence in trees, and

227 s transcriptional activation, especially for genes involved in secretion.

228 The present experiment targeted candidate genes involved in serotonin production, metabolism, tran

229 reactivity, as well as characterizing target genes involved in serotonin turnover in the zebrafish br

230 Furthermore, we show that UV-B induces genes involved in shoot development and organ patterning

231 At present, mutations in six genes involved in SR calcium release have been identifie

232 strated that beta-catenin directly regulates genes involved in sterol regulatory element binding tran

233 To gain insights on genes involved in stigma position in tomato, a bulk RNA

234 idation, and testing was FKBP5, a well-known gene involved in stress response, which serves as a de f

235 nrichment for evolutionarily young genes and genes involved in stress and defense.

236 of nitric oxide resulted in up-regulation of genes involved in stress response and down-regulation of

237 Sulfate transporters and genes involved in sulfate and Met metabolism were upregu

238 Finally, genes involved in sulfur assimilation, the glutathione-a

239 f numerous alternative mRNA transcripts from genes involved in synaptic plasticity and psychiatric di

240 This module contained many genes involved in synaptic signaling and neuroplasticity

241 an age-related upregulation in expression of genes involved in synaptogenesis, axonogenesis and neuro

242 Genes involved in synthesis and receptor pathways for ei

243 ism by repressing the expression of specific genes involved in TAG hydrolysis and fatty acid oxidatio

244 enchymal genes, such as Calponin (CNN1), and genes involved in TGF-beta signaling, such as AKT Serine

245 gloeosporioides COM1 (CgCOM1) developmental gene involved in the fungal conidial and appressorium fo

246 ocus on Ataxin-1 (ATXN1), a dosage-sensitive gene involved in the neurodegenerative disease spinocere

247 doublesex (Dsx), a key transcription factor gene involved in the sex determination cascade.

248 Genes involved in the "pancreatic secretion" pathway are

249 dules highlighted the enhanced expression of genes involved in the biosynthesis and transport of FAs,

250 Also, genes involved in the biosynthesis of precursors for ind

251 We find that genes involved in the cancer type-specific genetic subne

252 Up-regulated DEGs were enriched for genes involved in the cell wall metabolism, lipid transp

253 They include genes involved in the central nervous system-adrenal sig

254 ion positively correlated with expression of genes involved in the cholesterol synthesis pathway in p

255 tch pathway, particularly NOTCH4, as well as genes involved in the ciliome including CEP290 may play

256 Alterations of genes involved in the DNA damage repair pathway have bee

257 Mutations in other genes involved in the DNA damage response may simply enh

258 CpG islands associated with the promoters of genes involved in the early development of the central n

259 diated H2Aub repression to the activation of genes involved in the endoplasmic reticulum (ER) stress

260 mor shape were associated with expression of genes involved in the extracellular matrix (false discov

261 as a direct transcriptional activator of key genes involved in the Fe regulatory network, including b

262 Genes involved in the fibrotic response, including ACTA2

263 Furthermore, many genes involved in the flavonoid and phenylpropanoid path

264 ctions and induce mRNA expression of several genes involved in the formation of EC barrier and transp

265 d spreading, resulting in down-regulation of genes involved in the G2/M cycle and subsequent quiescen

266 ctors, CERK1, LEA, Laccase genes and several genes involved in the hormone signaling pathways.

267 tions (MTAs), some of which were adjacent to genes involved in the JA-defence pathway (opr7, aos1, 2,

268 Regions of CNA encompassed genes involved in the JAK/STAT pathway and epigenetic re

269 nalysis revealed the presence of 229 and 943 genes involved in the phenylpropanoid biosynthesis in le

270 positively with the expression levels of the genes involved in the phenylpropanoid pathway.

271 Pathway analysis identified up-regulation of genes involved in the proliferation, cell cycle, angioge

272 xidant status, and the expression of hepatic genes involved in the regulation of antioxidants, inflam

273 we investigated the epigenetic pattern of 12 genes involved in the regulation of GR signaling in two

274 and GDF15 modulate the expression of several genes involved in the regulation of hepatic lipid metabo

275 These data indicate that genes involved in the replication, packaging, and releas

276 In addition, our analysis indicates that genes involved in the response to environmental signals

277 Furthermore, it decreases the expression of genes involved in the signal transduction by the p53 cla

278 cond group, to which ISC1 belongs, comprises genes involved in the spindle checkpoint (BUB1, MAD1, BI

279 th VPA was associated with regulation of the genes involved in the steatogenic nuclear receptor perox

280 hat gigC regulates the expression of several genes involved in the sulfur assimilation and cysteine b

281 has led to the elucidation of hemp candidate genes involved in the syntheses of specialized metabolit

282 The expression of genes involved in the synthesis of reported metabolites

283 Furthermore, undiscovered genes involved in the synthesis of secondary metabolic b

284 spacers were enriched in sequences targeting genes involved in the transmission of iMGEs.

285 One of the genes involved in this incompatibility also causes melan

286 Infants with mutations in genes involved in tissue barrier fitness are predisposed

287 ), ventral veinless (vvl), and cut (ct), key genes involved in tracheal development, this study provi

288 Here, we analyzed host genes involved in trafficking networks to examine their

289 chondrial genome but also nearly all nuclear genes involved in transcription and replication of the m

290 tely restored by suppressor mutations in ten genes involved in transcription termination.

291 und to PGC-1alpha were intronic sequences of genes involved in transcriptional, signaling, or metabol

292 somes to monosomes and the downregulation of genes involved in translation and ribosome biogenesis.

293 t Hnf4a directly regulates the expression of genes involved in transmembrane transport and metabolism

294 phagocytosis activity and low expression of genes involved in triggering immune responses, regulatio

295 ciated with DNA methylation and silencing of genes involved in tumor suppression.

296 gnificant number of differentially regulated genes involved in tumorigenesis were expressed in a high

297 Expression of genes involved in unexpected heterotrophic processes inc

298 ted that ERRgamma activates transcription of genes involved in virtually all aspects of postnatal dev

299 Surprisingly, when mutant strains in the genes involved in virulence (JDeltaagr, JDeltacoaDeltavw

300 ficantly up-regulated uniquely at 48 hpi and genes involved in zinc finger CCCH protein, glycosyltran