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1 animals is the capability to perform in vivo gene manipulation.
2 newing XEN cells without the requirement for gene manipulation.
3 bility to determine protein function through gene manipulation.
4 nome sequences, and molecular techniques for gene manipulation.
5 patial and temporal control over the desired gene manipulation.
6 del has been widely used for T cell-specific gene manipulation.
7 ISPR array or a small RNA guide for targeted gene manipulation.
8  the use of artificial culture conditions or gene manipulations.
9 TFs) or nucleases (TALENs), enabling precise gene manipulations.
10  than solely focusing on large-effect single gene manipulations.
11                               Virus-mediated gene manipulation and circuit mapping showed that thermo
12 specific protein modification without target gene manipulation and enable potential future applicatio
13                                     Although gene manipulation and GDNF protein infusion into the bra
14                                              Gene manipulation and pharmacological approaches further
15 e data demonstrate an effective approach for gene manipulation and provide insights into the epigenet
16                         However, advances in gene manipulation and stem-cell therapy suggest cautious
17                                   Yet single gene manipulations and environmental interventions can s
18 ts the rapid, arrayed generation of multiple gene manipulations and is widely adaptable across cultur
19 ing to examine the channel activity, and (4) gene manipulations and other methods to determine the un
20 s or subjected to adenoviral vector-mediated gene manipulations and then to glucose-induced IRS-2 exp
21 distinct molecular programs, neuron-specific gene manipulations are essential.
22                           Recent advances in gene manipulation, automated behavioral acquisition at s
23 sequence (UAS) binary system is powerful for gene manipulation, but GAL4 expression is often too broa
24 n organism in which metabolic challenges and gene manipulation could address the enigmatic pathophysi
25  We developed a method that exploits GFP for gene manipulation, Cre recombinase dependent on GFP (CRE
26                    Similar to the effects of gene manipulation, declining levels of endogenous BST2 i
27 onclude that current artificial selection or gene manipulation experiments focus on pleiotropy.
28 ere, we combine RNA sequencing, viral-vector gene manipulation, functional brain imaging, and behavio
29                                  Therapeutic gene manipulation has been at the forefront of popular s
30        The elucidation of models with single-gene manipulations has also identified immune mechanisms
31 akthrough methodologies for gene editing and gene manipulation have also opened vast avenues of resea
32 stems, despite their considerable utility in gene manipulation, have pitfalls in certain scenarios, s
33 ine of three strains used as backgrounds for gene manipulations (i.e., C57, 129/SvJ, and WBB6).
34                                     Targeted gene manipulation in a complex microbial community is an
35 racing or cell lineage tracing combined with gene manipulation in a second lineage.
36 aches offer a powerful strategy for targeted gene manipulation in any plant species.
37 highlighting the transformative potential of gene manipulation in combating this important parasitic
38 c animals are corroborated by in vitro acute gene manipulation in cultured wild type adult mouse vent
39  control, during which the full potential of gene manipulation in insect systems will ultimately be r
40 tives for precise large insertions or stable gene manipulation in mammalian cells.
41                             Increased use of gene manipulation in mice (e.g., targeted or random muta
42 mployed for tamoxifen-inducible Cre-mediated gene manipulation in microglia and for fate mapping of m
43  the social defeat phenotype induced by Fosb gene manipulation in MSN subtypes.
44                                              Gene manipulation in the mouse has discovered multiple c
45                    Through the approaches of gene manipulation in the mouse model, a substantial body
46 nal significance of this gene using targeted gene manipulation in the mouse.
47 g its functional significance using targeted gene manipulation in the mouse.
48 otics, fecal microbiota transplantation, and gene manipulation in the treatment of IBD.
49           In this study, we used conditional gene manipulations in mice and explored the roles of bet
50 ner is not applicable to cell tracing and/or gene manipulations in more than one lineage at a time.
51                    Model systems with target gene manipulations involving Fas ligand, Fas, perforin,
52          Spatiotemporally regulated targeted gene manipulation is a common way to study the effect of
53               Embryonic stem (ES) cell-based gene manipulation is an effective method for the generat
54 complicated because the potential outcome of gene manipulation is difficult to predict.
55   Here, by use of biologic, biochemical, and gene manipulation methods in human polymorphonuclear neu
56 s with an interest in studying the effect of gene manipulation on phosphoinositide metabolism in zebr
57 ditions where activation is obtained through gene manipulation or encounters with environmental signa
58 both long-term imaging and real-time ex vivo gene manipulation, our simple culture protocol provides
59                   Clonal NSC REST and CoREST gene manipulation paradigms further revealed that CoREST
60  CD4Cre transgenic model for T cell-specific gene manipulation, particularly when lung pathophysiolog
61 ugh various experimental techniques, such as gene manipulation, pharmacological inhibition, and prote
62 ecent years as a highly efficient RNA-guided gene manipulation platform.
63 ith high-throughput model systems, efficient gene manipulation provides an increasingly powerful tool
64 or behavior may help to parse the effects of gene manipulations relative to strain differences in mut
65  implemented viral-mediated isoform-specific gene manipulation, RNA-sequencing, advanced bioinformati
66 ng these assays in the orofacial area during gene manipulation should assist in uncovering mechanisms
67 n between Notch and Wnt, we employed a novel gene manipulation strategy in cultured embryonic kidneys
68 his interpretation comes from the results of gene manipulation studies in mice, as well as the sequen
69    Although often demonstrated in artificial gene manipulation studies in model organisms, and some e
70                                     In vitro gene manipulation studies revealed that FGF1 is sufficie
71 ization of QNS offers a promising target for gene manipulation studies toward the production of novel
72 components and informing targeted functional gene manipulation studies.
73 e used to assess neuronal cultures following gene manipulation such as RNAi, and to study induced plu
74                                              Gene manipulation, such as transfection and transduction
75 s, there is a need for an inner ear-specific gene manipulation system for loss- and gain-of-function
76  progress in Babesia transfection, different gene manipulation systems, and the applications of gene
77                     Continual refinements in gene manipulation technology in mice offer the opportuni
78      There are currently no interventions or gene manipulations that can prevent, stop or reverse the
79       Through gene coexpression and targeted gene manipulations, the malleobactin pathway was success
80 c analysis, metabolomics analyses, and mouse gene manipulation to investigate the effects of mitochon
81 ics, including gene function and therapeutic gene manipulation, to be explored in vivo, which is more
82 n tested directly, mainly due to the lack of gene manipulation tools in SCTB.
83 ir gene transfer methodology and build their gene manipulation tools would enable mechanistic dissect
84 s gene function due to the lack of efficient gene manipulation tools.
85 k of high-throughput molecular resources and gene-manipulation tools.
86  human placentation, and is also amenable to gene manipulation using genome-editing techniques.
87 ey underscore the advantage of investigating gene manipulation using in vivo functional imaging.
88 by exploiting placental trophoblast-specific gene manipulation using lentiviral vectors, which has be
89                                 Cre-mediated gene manipulation using transgenic lines that express Cr
90                          Adenovirus-mediated gene manipulations were used in vitro.
91 is highly efficient for single and multiplex gene manipulation, without compromising T cell function,