ライフサイエンスコーパス: gene transcription

1 P transcription factors and activates ADGRB1 gene transcription.

2 valuate indels, orientating them relative to gene transcription.

3 ation of DNA spatial folding, thus affecting gene transcription.

4 -localized PHB1 is an important regulator of gene transcription.

5 f fluid movement and initiate flow-dependent gene transcription.

6 -1 regulatory circuits that control collagen gene transcription.

7 e epigenetic changes to suppress thermogenic gene transcription.

8 4), and FOXO1(ser256) as well as blunts AgRP gene transcription.

9 d Nrf2 nuclear translocation and antioxidant gene transcription.

10 ppaB (NF-kappaB) activity and Il1b and Nlrp3 gene transcription.

11 c flux and signal transduction, particularly gene transcription.

12 rminal proteins are epigenetic regulators of gene transcription.

13 hat is mediated by DNA damage and repair and gene transcription.

14 de association study (GWAS), and single-cell gene transcription.

15 putatively function to locally cis-activate gene transcription.

16 rendered MtPrpR incapable of regulating MCC gene transcription.

17 egfa promoters and enhancers, and controlled gene transcription.

18 nt nuclear translocation for full Wnt target gene transcription.

19 esidues, thus modulating redox signaling and gene transcription.

20 ase II (RNA-POL-II) recruitment and activate gene transcription.

21 regulation of this occurs at the level of NE gene transcription.

22 te with TBX5 and repress its role in cardiac gene transcription.

23 beta II expression inhibits YAP/TAZ-mediated gene transcription.

24 downstream events, such as cell motility and gene transcription.

25 transcriptional regulator to influence atxA gene transcription.

26 and HIF-1alpha levels and enhanced aromatase gene transcription.

27 e E2F1 protein synthesis, leading to DEPDC1B gene transcription.

28 on and downstream beta interferon (IFN-beta) gene transcription.

29 ly condensed form of chromatin that silences gene transcription.

30 respiratory factor 2 (Nrf2)-dependent Sirt3 gene transcription.

31 chains and play critical roles in regulating gene transcription.

32 rovide evidence that SM also facilitates EBV gene transcription.

33 and acts as a coactivator to stimulate Bcl-2 gene transcription.

34 altered protein stability, DNA binding, and gene transcription.

35 The JMJD6 gene at 17q21-ter activates gene transcription.

36 yd3, a histone methyltransferase involved in gene transcription.

37 ereby inducing a dominant-negative effect on gene transcription.

38 anslocation and blocking NF-kappaB-dependent gene transcription.

39 ters, especially super-enhancers, to inhibit gene transcription.

40 transcription start site to stabilize their gene transcription.

41 of chronic adolescent stress at the level of gene transcription.

42 ure, performing a central role in regulating gene transcription.

43 ontrol of transition-metal catalysis through gene transcription.

44 nery in cholangiocytes to support fibrogenic gene transcription.

45 ohesion and facilitate long-range control of gene transcription.

46 is a central regulator of the cell cycle and gene transcription.

47 inogenesis in the endometrium by controlling gene transcription.

48 ression impaired ETV1's ability to stimulate gene transcription.

49 rogramming leukemic-associated chromatin and gene transcription.

50 between the dynamics of DNA supercoiling and gene transcription.

51 sent in one orientation with respect to V(H) gene transcription.

52 i and is involved in modulating ER-dependent gene transcription.

53 x remodels chromatin structure and regulates gene transcription.

54 1 contains an AD required for Rap1-dependent gene transcription.

55 uced breast cancer resistance protein (BCRP) gene transcription.

56 synthesis as well as c-di-GMP-induced stalk gene transcription.

57 t blocks repressor complexes to enable viral gene transcription.

58 e between ligand-receptor binding and target gene transcription.

59 CSCs by epigenetically activating Wnt target gene transcription.

60 hibit increased levels of sigma(F) -directed gene transcription.

61 c DNA demethylation to activate pluripotency gene transcription.

62 gating postreplicative intermediate and late gene transcription.

63 c receptor but also directly participates in gene transcription.

64 ing of Cav1.2 channels to activity-dependent gene transcription.

65 ression promotes puncta formation and target gene transcription.

66 interact with nuclear receptors to regulate gene transcription.

67 dogenous beta-catenin, and subsequent target gene transcription.

68 ation, controlling the time to onset of Irf4 gene transcription.

69 n family member that predominantly regulates gene transcription.

70 genome in the virion and regulation of viral gene transcription.

71 ruitment of HIF1alpha, leading to HIF target gene transcription.

72 binding protein LAG-1/CSL to activate target gene transcription.

73 mplex, that facilitates the initial steps of gene transcription.

74 ormation, and DHFR (dihydrofolate reductase) gene transcription.

75 depend on precise spatiotemporal control of gene transcription.

76 to form a complex that controls TE-specific gene transcription.

77 tones through their bromodomains to regulate gene transcription.

78 iotin to M. smegmatis cultures repressed tam gene transcription.

79 iruses through the inhibition of early viral gene transcription.

80 prostaglandin D(2) secretion, and proteases gene transcription.

81 ear translocation of ERK5 and stimulation of gene transcription.

82 EF), causing subsequent repression of target gene transcription.

83 ns) that regulate constitutive and inducible gene transcription.

84 VLT and ORF63 proteins, induces broad viral gene transcription.

85 ion-point for regulatory-signals controlling gene-transcription.

86 e diverse DNA-templated processes, including gene transcription(1-3).

87 unit macromolecular assembly responsible for gene transcription, a highly regulated process conserved

88 promotes inflammatory and stress-responsive gene transcription across a range of cell types in respo

89 NAs expression was independent of their host gene transcription, alternative splicing rates were lowe

90 s biological processes such as regulation of gene transcription and activities of enzymes and cell si

91 days postinfection, there is a loss of lytic gene transcription and an increase in the numbers of neu

92 P1 in cellular processes such as DNA repair, gene transcription and cell death have allowed the inves

93 hich is an epigenetic modifier implicated in gene transcription and cell differentiation, is essentia

94 DM5B controls H3K4me3/2 levels and regulates gene transcription and cell differentiation, yet the con

95 s regulates specific cellular events such as gene transcription and cell proliferation.

96 downstream signalling focussed on regulating gene transcription and chromatin modification to control

97 oordinate neural activity-induced changes in gene transcription and contribute to sensorimotor learni

98 ream of IkappaBalpha degradation, preventing gene transcription and cytokine secretion in response to

99 ings of an association between CD8(+) T-cell gene transcription and disease outcome in IBD.

100 artment in which essential processes such as gene transcription and DNA replication occur.

101 ancer is a potent regulator of mast cell Il9 gene transcription and epigenetic modification at the Il

102 modification is known to be associated with gene transcription and frequently used as a mark to inve

103 one insulator site in HSV-1 modulates lytic gene transcription and heterochromatin deposition as the

104 all the transcription factors necessary for gene transcription and hypertrophy.

105 re alterations involved in the regulation of gene transcription and in disease is increasing.

106 demethylates H3K9me1 and H3K9Me2 to increase gene transcription and is upregulated in tumors, includi

107 1 complex-catalyzed H3K4me3 promotes histone gene transcription and maintains normal chronological li

108 regions of genes is negatively regulated by gene transcription and may be modified by early-life exp

109 e PcG complexes can also positively regulate gene transcription and modify non-histone substrates in

110 nterfere with FOXO3 target promoter binding, gene transcription and modulate the physiologic program

111 t from cell type-specific regulation of both gene transcription and mRNA stabilities.

112 ined broad patterns of association involving gene transcription and nearby SSV breakpoints, global al

113 ve of vitamin A, exhibits diverse effects on gene transcription and non-genomic regulatory pathways.

114 epigenetic modification, is associated with gene transcription and nuclear organization, and ultimat

115 Wnt ligands has significant implications for gene transcription and opens up a novel avenue to interf

116 ch in turn activated NF-kappaB to induce IL6 gene transcription and orchestrate a pro-inflammatory pr

117 C and the phytochrome interact to coordinate gene transcription and other responses, but the contribu

118 6me3 or DNA methylation, interfere with host gene transcription and pre-mRNA processing genomewide an

119 chromatin is essential for regulating global gene transcription and protecting genome stability, and

120 been demonstrated for protein ion channels, gene transcription and protein activation.

121 ree transcription-translation system execute gene transcription and protein biosynthesis in a timely

122 nase) signalling, and was unrelated to BACE1 gene transcription and protein degradation.

123 h MyoD at shared DNA motifs to direct global gene transcription and repression of the myogenic progra

124 gametogenesis, spermatocytes undergo robust gene transcription and store many transcripts in the cyt

125 s reveal a mechanism whereby OTUD5 regulates gene transcription and suppresses tumorigenesis by deubi

126 cellular processes such as the regulation of gene transcription and the enhancement or inhibition of

127 The effect of PDF on clock gene transcription and the known role of PDF in enhancin

128 r matrix formation, epigenetic regulation of gene transcription and the reprogramming of cellular met

129 ealed that PAX2 can inhibit estrogen-induced gene transcription and this effect is enhanced by tamoxi

130 ells, antigen-processing machinery component gene transcription and translation were upregulated, con

131 gments to cleavage by RAG is associated with gene transcription and with epigenetic marks characteris

132 lts demonstrate a key role for HDAC1 in PU.1 gene transcription and, more importantly, uncover a nove

133 alian phenotype are hypothesized to regulate gene transcription and/or to be under selection.

134 e key protein effectors in the regulation of gene transcription, and in many cases their activity is

135 The wave does not require sustained gene transcription, and is not governed by regulated Fog

136 ested inhibited viral genome replication and gene transcription, and none of them affected host cellu

137 es chromatin accessibility, enhances histone gene transcription, and promotes HLB formation.

138 endothelial barrier function, regulators of gene transcription, and specific kinases predicted to me

139 al for setting up the spatial environment of gene transcription, and substantial progress has been ma

140 diated p300 knockdown, inhibited ER-mediated gene transcription, and suppressed expression of numerou

141 the vTAs into a complex is critical for late gene transcription, and thus, deciphering the architectu

142 unctions of CRMs and their effects on nearby gene transcription are highly dynamic and context-specif

143 tors normally implicated in RNAP II-mediated gene transcription are more enriched at tRNA than at mRN

144 lncRNA Neat1 revealed widespread changes in gene transcription, as well as perturbations of histone

145 d that unique patterns of activity-dependent gene transcription associated with brain-derived neurotr

146 tiating promoter-like sites is important for gene transcription at high salt concentration.

147 of this writing, more than 21,000 studies on gene transcription at the molecular level have been publ

148 on is mediated exclusively via regulation of gene transcription at the nuclear level.

149 vides insight into the mechanisms regulating gene transcription at the population scale, of which loc

150 ansfection, inhibits SM-dependent late lytic gene transcription but not transcription of other EBV ge

151 Both require gene transcription, but brain SGR uses an RNA intermedia

152 gene expression, H3K4me3 facilitates histone gene transcription by acting as a boundary to restrict t

153 dies showed that CBFA2T3 inhibits RAR target gene transcription by acting at an early step to regulat

154 (MYOCD), a master regulator for SMC-specific gene transcription by binding to SRF to form the MYOCD/S

155 olecular mechanism of nutrient regulation of gene transcription by dynamic O-GlcNAcylation of TBP.

156 Direct repression of anoctamin 1 (ANO1) gene transcription by Gli proteins.

157 L family of methyltransferases that controls gene transcription by H3K4 methylation (H3K4me).

158 Steroid receptors activate gene transcription by recruiting coactivators to initiat

159 e show that enCRISPRa and enCRISPRi modulate gene transcription by remodeling local epigenetic landsc

160 Gene transcription by RNA polymerase II is regulated by

161 many essential cellular processes including gene transcription, chromatin remodelling and mRNA proce

162 how individual interactions between the late gene transcription components are critical for both the

163 Although critical roles of eRNA in gene transcription control have been increasingly realiz

164 data thus support that much of BMAL1 target gene transcription depends on BMAL1 capacity to rhythmic

165 n interactions mediating chromatin-templated gene transcription, DNA recombination, replication and r

166 multiple DNA-templated processes, including gene transcription, DNA repair, and replication.

167 ssembly and reassembly of nucleosomes during gene transcription, DNA replication and DNA repair(2).

168 phosphorylation, and type I interferon (IFN) gene transcription downstream of TLR4.

169 ired for the transition from early to middle gene transcription during phage infection.

170 duration and amplitude of subsequent target gene transcription during post-embryonic development.

171 -time visualization of native YAP and target gene transcription dynamics, we show that a cycle of fas

172 show that ivermectin inhibits HAdV-C5 early gene transcription, early and late protein expression, g

173 ignificantly with those bound by the S-phase gene transcription factor E2F1.

174 ated that induction of one of the identified genes, transcription factor SOX2, promoted cutaneous wou

175 VOR induces a consistent level of host cell gene transcription following intermittent exposure.

176 inflammatory mediators and reduced antiviral gene transcription following RIG-I activation at term de

177 enetic modification that directly stimulates gene transcription from chromatin.

178 Epigenetic regulation of gene transcription has been shown to coordinate with nut

179 Age- and sex-related alterations in gene transcription have been demonstrated, however the u

180 n of its activity results in altered meiotic gene transcription, impairment of double-stranded breaks

181 ocation, DNA binding, and androgen-dependent gene transcription in a low androgen environment.

182 Yin Yang 1 (YY1) regulates gene transcription in a variety of biological processes.

183 n a deeper understanding of the evolution of gene transcription in and between plant species, we perf

184 aled down-regulation of CAV1, CAV2, and CAV3 gene transcription in BSM from models of obstructive bla

185 ecome nuclear enriched and facilitate target gene transcription in cells with diminished levels of ca

186 to transduce a signaling cascade leading to gene transcription in cells.

187 factors through phase separation to sustain gene transcription in chromatin for cancer cell prolifer

188 Inflammatory gene transcription in damaged hepatocytes was attenuated

189 nd cellular contraction inhibited Wnt target gene transcription in developing Drosophila imaginal dis

190 o the program of synaptic activity-regulated gene transcription in developing neurons.

191 Nerve injury induces changes in gene transcription in dorsal root ganglion (DRG) neurons

192 ility, rewire cellular metabolism, and alter gene transcription in hepatocytes and embryonic stem cel

193 chromosome segregation, and also influences gene transcription in higher eukaryotes.

194 and dynamics and thereby crucially regulate gene transcription in higher eukaryotes.

195 eruginosa type I-F Cas proteins, we activate gene transcription in human cells.

196 bling enhancer function in regulating LILRB1 gene transcription in human NK cells.

197 B signaling pathway and trigger inflammatory gene transcription in isolated primary splenocytes.

198 The first was regulation of early gene transcription in lambda, the study of which began w

199 a specific histone demethylase for lipogenic gene transcription in liver.

200 diated hedgehog signaling and Gli-controlled gene transcription in living cells (IC50 = 230 nM), prov

201 oteins are important regulators of virulence gene transcription in many pathogens; they also control

202 n this study, we asked whether CHD7 promotes gene transcription in neural progenitor cells via change

203 key mediators of synaptic activity-regulated gene transcription in neurons, both during development a

204 ode calcium signals into specific changes in gene transcription in plant cells.

205 n of gene expression, a key factor governing gene transcription in polyploids.

206 y which glucagon and insulin increased FGF21 gene transcription in primary hepatocyte cultures.

207 ctor kappaB) pathway and NF-kappaB-dependent gene transcription in recipient endothelial cells and th

208 epigenetically activates pluripotency factor gene transcription in response to chemotherapy.

209 can bind gene promoters and regulate target gene transcription in response to DNA damage.

210 tress protection by activating or repressing gene transcription in response to protein misfolding, on

211 ng a transient down regulation in dystrophin gene transcription in the absence of dystrophin gene exc

212 re to POPs differentially alters genome-wide gene transcription in the adipose tissue from mother pol

213 Late gene transcription in the beta- and gammaherpesviruses d

214 MENT How does the pattern of immediate early gene transcription in the brain relate to the storage an

215 Neuroepigenetic pathways regulate gene transcription in the brain.

216 inantly regulates the 12-hour rhythmicity of gene transcription in the mouse liver and demonstrate th

217 n IPF and this MAPK has a key role in target gene transcription in the TGF-beta pathway.

218 rticular regulatory topology to control Hoxd gene transcription in time and space, we either deleted

219 , the functional consequence of AP-1 loss on gene transcription in uterine fibroids remains poorly un

220 he physical nanoenvironment of chromatin and gene transcription in vitro.

221 show that crotonylation selectively affects gene transcription in vivo in a manner dependent on Gcn5

222 ng tumor angiogenesis, the activation of the gene transcriptions in vascular endothelial cells (ECs)

223 tion of TBX3 abundance impacts on Wnt target genes transcription in a beta-catenin- and TCF/LEF-depen

224 promoter regions and activate developmental gene transcription, including that of the dev operon.

225 ival of infection, but also facilitated host gene transcription, including the expression of antivira

226 on to DNA replication for activation of late gene transcription initiation.

227 on cellular metabolism, immune function, and gene transcription involved in innate host responses to

228 Gene transcription is a noisy process, and cell division

229 Therefore, the initiation of early gene transcription is attenuated following DNA replicati

230 We show that differential gene transcription is closely linked to the variation in

231 data from CommonMind Consortium showed that gene transcription is controlled by genetic variants pro

232 the authors recently revealed that prolactin gene transcription is highly dynamic and stochastic yet

233 Eukaryotic gene transcription is regulated by a large cohort of chr

234 spite its important role, regulation of Ido1 gene transcription is unknown.

235 iated inactivation of HIF1alpha-driven CXCR4 gene transcription, leading to mobilization of immature

236 GrlR was not sufficient to induce virulence gene transcription; mechanical stimuli were required for

237 P-ribose polymerase 1 (PARP1), whose role in gene transcription modulation has been well established.

238 control of its distribution by the timing of gene transcription, mRNA translation, and protein transp

239 ression, the effects of these genes on human gene transcription networks, and the pathophysiological

240 ell division cycle is an important source of gene transcription noise.

241 d chromosomes derived from Ae. longissima on gene transcriptions of the wheat landrace Chinese Spring

242 oes not need to interact with AR-FL to drive gene transcription or DNA-damage repair in prostate canc

243 riments, we show that Msp does not alter the gene transcription or protein content of key enzymes res

244 LI family zinc finger (GLI)-mediated diverse gene transcription outcomes are strictly regulated and a

245 pport the concept of targeting Rho-regulated gene transcription pathways as a promising therapeutic a

246 echanistic understanding of the dysregulated gene transcription patterns in SCZ and creates more effi

247 how chromatin accessibility correlated with gene transcription positively in a highly heterogeneous

248 TWIST1, in turn, regulates endothelial gene transcription, positively of proangiogenic KDR and

249 n turn could arise via mutations that affect gene transcription, posttranscriptional processes, or co

250 It is widely accepted that cAMP regulates gene transcription principally by activating the protein

251 The var gene transcription profiles of sub-clones measured by re

252 growth factor, could also modify macrophage gene transcription, providing further evidence for a bid

253 lude that the diurnal cycle of anion channel gene transcription, rather than the physiological signal

254 ed into an elaborate epigenetic mechanism of gene transcription regulation during evolution.

255 In addition to gene transcription regulation, modulation of protein lev

256 DNA methylation acts as a mechanism of gene transcription regulation.

257 The [Fe(2)S(2)]-RsrR gene transcription regulator senses the redox status in

258 regulation, epigenetic control of autophagy gene transcription remains unclear.

259 Unlike BRD4L, the role of BRD4S in gene transcription remains unclear.

260 rictive silencer factor) protein, a neuronal gene transcription repressor protein, is responsible for

261 ich affect synaptic vesicle mobilization and gene transcription, respectively.

262 Myocardial stress-gene transcription responds instead through H3K27-acetyl

263 nique metabolites, and has a distinct global gene transcription response to FLs compared to the type

264 model describes the essential components of gene transcription, signal transduction, extra and intra

265 with cohesin and are significantly closer to gene transcription start sites than nonclustered CTCF si

266 e enriched and more closely located to viral gene transcription start sites than would be expected by

267 iate with GATA1 and stimulate GATA1-mediated gene transcription, suggesting that SIX1-GATA1 physical

268 orts a direct interaction with regulators of gene transcription, suggesting that the combination of t

269 inds to the collagen IV promoter, commencing gene transcription that is reduced by inhibiting EGFR, d

270 eparation(1-4), which is thought to underlie gene transcription through condensation of the large-sca

271 Estrogen receptor alpha (ERalpha) regulates gene transcription through two activation functions (ERa

272 loys a broad range of mechanisms to regulate gene transcription throughout the organism's complex lif

273 cle through integration but suppressed HIV-1 gene transcription, thus allowing the establishment of l

274 ck-in mice, mutant TBP inhibits SP1-mediated gene transcription to down-regulate INPP5A, a protein th

275 uper-enhancers, which direct vigorous immune gene transcription to establish the antiviral state.

276 ous cellular effector functions ranging from gene transcription to exocytosis.

277 Phi significantly altered the sensitivity of gene transcription to glucocorticoids.

278 tions constitutively activate NRF2-dependent gene transcription to promote many of the cancer hallmar

279 -specific DNA binding protein that activates gene transcription to regulate cell survival and prolife

280 protein complexes, which activate or repress gene transcription to regulate development, homeostasis,

281 in a substantial increase in muscle-specific gene transcription (up to 400-fold) when delivered using

282 rs who share similar structures and regulate gene transcription using a combination of acyl-CoAs and

283 For regulation of lipogenic gene transcription, various known lipogenic transcriptio

284 r function in CLL cells, stimulating PKCbeta gene transcription via increased association of SP1 and

285 biological responses of living cells such as gene transcription via previously underappreciated means

286 CD8(+) gene transcription was clearly associated with IBD in th

287 RANKL gene transcription was robustly induced by the progester

288 An effect of PTEN on Nkx3.1 gene transcription was seen in vitro, but not in vivo.

289 Antiviral effector gene transcription was strongly induced during the log p

290 mine this balance by activating pro-atrophic gene transcription when present in muscle fiber nuclei.

291 fibroblasts with LIGHT induced inflammatory gene transcription, whereas stimulation with TGFbeta1 in

292 activities, and corresponding regulation on gene transcription, which it models as a sparse network

293 TEN null cells were found to continue global gene transcription, which may activate a survival mode.

294 Glycolysis is necessary for early gene transcription, while glutaminolysis is necessary fo

295 The Wnt signalling network determines gene transcription with free intracellular Ca(2+) ( Cai2

296 (MRTF)/serum response factor (SRF)-mediated gene transcription with good potency (IC(50) = 180 nM).

297 obust perturbations of enhancer activity and gene transcription with minimal off-targets.

298 opological stress during DNA replication and gene transcription, with no previously known role in B c

299 chromatic regions of chromosomes, inhibiting gene transcription within these regions and promoting a

300 reased Yap protein levels and blunted target gene transcription without affecting Yap transcript abun