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3 e inhibition of transcription disrupts these gene-related folding features without altering higher-or
4 ion and pathway analysis showed that several genes related in blood digestion and host-parasite inter
5 ive intestinal polypeptide (VIP), calcitonin-gene related peptide (CGRP), substance P (SP), neuropept
6 rachial nucleus (PBel) containing calcitonin gene related peptide (PBel(CGRP) neurons) are critical f
7 s expressing Phox2b, substance P, calcitonin-gene related peptide, and the serotonin receptor 5-HT(3)
8 he therapeutic potential of alpha-calcitonin gene-related peptide (alpha-CGRP) has been limited becau
9 of Calca, which encodes the alpha-calcitonin gene-related peptide (alpha-CGRP), in intestinal KLRG1(+
10 )-5, together with Calca-encoding calcitonin gene-related peptide (CGRP) and its cognate receptor com
12 ce that antisera directed against calcitonin gene-related peptide (CGRP) and substance P could neutra
13 bited release of the neuropeptide calcitonin gene-related peptide (CGRP) from dorsal root ganglion ne
14 ng evidence that the neuropeptide calcitonin gene-related peptide (CGRP) has a key role in migraine.
15 d disorder.SIGNIFICANCE STATEMENT Calcitonin gene-related peptide (CGRP) has long been implicated in
17 CANCE STATEMENT: The neuropeptide calcitonin gene-related peptide (CGRP) is a central player in migra
21 ne patient.SIGNIFICANCE STATEMENT Calcitonin gene-related peptide (CGRP) monoclonal antibodies (CGRP-
22 bution to cancer anorexia made by calcitonin gene-related peptide (CGRP) neurons in the parabrachial
26 lly administered, small-molecule, calcitonin gene-related peptide (CGRP) receptor antagonist under in
28 fibers and their relationship to calcitonin gene-related peptide (CGRP) staining in the dorsal horn.
30 aine, we show that application of calcitonin gene-related peptide (CGRP) to the rat dura mater produc
31 l nerve fibers immunoreactive for calcitonin gene-related peptide (CGRP), a marker for polymodal noci
32 d with a labeled antibody against calcitonin gene-related peptide (CGRP), a marker of nociceptive sen
33 ectly respond to STm by releasing calcitonin gene-related peptide (CGRP), a neuropeptide that modulat
35 especially those also expressing calcitonin gene-related peptide (CGRP), and in central processes of
36 zed monoclonal antibody targeting calcitonin gene-related peptide (CGRP), is being investigated as a
38 urons that respond to CO2 express calcitonin gene-related peptide (CGRP), we hypothesized that CGRP m
40 ify the location, morphology, and calcitonin gene-related peptide (CGRP)-immunoreactivity of uterine
44 th IL-33 and the receptor for the calcitonin-gene-related peptide (CGRP); and demonstrate that up- or
45 we used stimulated immunoreactive Calcitonin Gene-Related Peptide (iCGRP) release as a measure of noc
46 glutamatergic neurons expressing calcitonin gene-related peptide alpha (CALCA) are NREM-sleep active
47 ogical agents to treat pain (anti-calcitonin gene-related peptide and anti-nerve growth factor) are a
48 blood levels of the neuropeptide calcitonin gene-related peptide but increases the neuropeptide subs
49 nal sensory afferents, increasing calcitonin gene-related peptide expression and basal trigeminal noc
51 tivation, including expression of calcitonin gene-related peptide in the trigeminal ganglion and c-Fo
52 is of the major metabolite of the calcitonin gene-related peptide recepotor antagonist BMS-846372 is
53 gepant is an oral, small-molecule calcitonin gene-related peptide receptor antagonist for acute migra
54 f a migraine attack with the oral calcitonin gene-related peptide receptor antagonist rimegepant resu
56 lly administered, small-molecule, calcitonin gene-related peptide receptor antagonist that may be eff
59 ceptor agonists, and the gepants: calcitonin gene-related peptide receptor antagonists, in a preclini
61 clonal antibody that inhibits the calcitonin gene-related peptide receptor, for the prevention of epi
62 lectrophysiology, Ca(2+) imaging, calcitonin gene-related peptide release assay from tissues, protein
63 se the sensory neuropeptide CGRP (calcitonin gene-related peptide) regulates host responses during in
64 nd neuropeptides (substance P and calcitonin gene-related peptide) using genetic and pharmacological
67 s induced by aristolochic acid I, calcitonin gene-related peptide, endothelin-1, gentamicin, norepine
68 y of galcanezumab, an antibody to calcitonin gene-related peptide, in patients with migraine who had
69 humanized monoclonal antibody to calcitonin gene-related peptide, may be a preventive treatment for
72 re likely to exhibit the expected changes in gene-related physiology, behaviour and subjective experi
73 aining the sensory neuropeptides, calcitonin gene-related polypeptide, and substance P, occurred at v
74 (sympathetic neuron marker; TH), calcitonin gene-related protein (peptidergic nociceptor marker; CGR
78 ives expressed 2 antisense RNA1, a noncoding gene related to cardiovascular function) and rs269868-C/
81 atulin biosynthesis and contribution of each gene related to the different catalytic enzymes in the b
85 S. costatum exhibited downregulation of the genes related to a series of metabolic activities (e.g.
88 ion, including CDHR3 and CDH26, and in other genes related to airway epithelial integrity and immune
89 eder) gut microbiome samples containing more genes related to amino acid metabolism, whereas N. aquil
90 n knockdown hNPCs, and expression changes to genes related to AMPK signaling and protein translation
91 iation analyses identified several candidate genes related to animal resilience to environment change
95 es, and integration sites often cluster near genes related to antibiotic resistance, virulence, and p
96 copy number alterations in the MICA and MICB genes related to antibody-dependent cell-mediated cytoto
97 -inflamed GEP contained IFN-gamma-responsive genes related to antigen presentation, chemokine express
98 phic forms also suppressed the expression of genes related to antigen processing and presentation, in
100 K2 in liver cells results in upregulation of genes related to apoptosis and down-regulation of genes
101 uences, the relative abundance of functional genes related to assimilatory nitrate reduction in the e
103 t AP2 controls meristem arrest by repressing genes related to axillary bud dormancy in the SAM and ne
105 e dams exhibited reduced brain expression of genes related to axonogenesis, deficient thalamocortical
106 cell progenitors have reduced expression of genes related to B cell lineage, IL-7 signaling, and cel
107 gnificant number of differentially expressed genes related to biosynthesis of secondary metabolites,
110 scriptome comparisons revealed that multiple genes related to carboxy-terminal domain (CTD) family pr
112 ut total carotenoids level and expression of genes related to carotenoid biosynthesis were increased,
117 strong transcriptome changes, especially in genes related to cell proliferation and metabolic functi
118 d Postn+ population preferentially expresses genes related to cell proliferation and neuronal develop
120 dulating the expression of a large number of genes related to cell wall composition and metabolism, a
121 cific transcription patterns, e.g. edema and genes related to cellular invasion, and 10 radiogenomic
122 1) BMI97 (97 loci), (2) BMICNS (54 loci near genes related to central nervous system [CNS]), and (3)
124 LPAIV induces decreases in the expression of genes related to ciliary activity in vivo and alters mul
125 peared to be different modalities for target genes related to classic immunosuppressive function vs.
127 analysis resulted in the upregulation of the genes related to common defense mechanisms for black spo
128 ntigen burden was positively associated with genes related to cytolytic activity and immune checkpoin
132 to play critical roles in the expression of genes related to differentiation and dedifferentiation.
134 as, and the relative abundance of functional genes related to dissimilatory nitrate reduction in the
135 In a genome-wide screen, we discover BCL genes related to diverse molecular processes, including
136 iotropic regulator that influences up to 252 genes related to diverse processes including chemotaxis,
137 ic degradation, and a complete repertoire of genes related to DNA repair and protection that includes
140 Subpopulations of E. coli PI-7 expressed genes related to dormancy and persister cell formation d
141 r, we identified several important candidate genes related to drought and heat stress, and revealed i
142 es of positive selection for FGF3 and FGF11, genes related to ear and tooth development and hypoxia,
144 ent, while Tcf21+ CFs differentially express genes related to ECM maturation at P7 and immune crossta
147 t population-specific selection including at genes related to endocrine disruption, there was no stro
148 trimethylation (H3K27me3), and inhibition of genes related to epithelial-to-mesenchymal transition (E
149 tory cytokines and altered the expression of genes related to epithelial-to-mesenchymal transition (E
150 lignancy through enhancing expression of the genes related to epithelial-to-mesenchymal transition.
151 eir proximal promoters, and notably enriched genes related to ER functions rather than those for cell
152 , RNA sequencing from 3 patients showed that genes related to erythroid maturation were down-regulate
153 th established roles in asthma and atopy and genes related to extracellular matrix, immunity, cell ad
155 mRNA sequencing demonstrated that hallmark genes related to fatty acid metabolism were highly expre
157 injury elicits changes in the expression of genes related to fatty acid synthesis and peroxisome pro
158 ll-for-gestational-age (SGA) to identify new genes related to fetal growth and neonatal body composit
160 inherits alleles of parental isolating major genes related to flowering time from one parent and alle
161 There was downregulation of Eimeria spp. genes related to gamete fusion, oocyst shedding, mitosis
162 the mutant and the altered expression of key genes related to gametophyte and seed development could
163 patocellular expression of gammaH2A.X and of genes related to genotoxic stress, as well as STAT3 phos
164 s covering up to 26 genes showed that mostly genes related to glucose metabolism, immune system and d
165 TGFbeta/BMP antagonists, a downregulation of genes related to glycolysis and the TCA cycle, and a low
167 ulators of ACE2 in the human lung, including genes related to histone modifications, such as HAT1, HD
168 atic biallelic loss-of-function mutations in genes related to homologous recombination DNA repair, co
169 ic analysis revealed differentially enriched genes related to hypertrophy, inflammation, and fibrosis
170 hs had significantly increased expression of genes related to immune response and apoptosis, which ma
172 ownregulated after E-cadherin knockdown, and genes related to increased extracellular matrix, cell ad
175 individuals with primarily hepatic IR, while genes related to inflammation were upregulated in indivi
176 er supported by enrichment among upregulated genes related to inflammation, JAK-STAT and TNF-alpha si
177 l gene expression levels and upregulation of genes related to inflammation, the extracellular matrix,
180 dition, there was differential expression of genes related to innate immunity, including genes encodi
185 In addition, studies using RNAi to target genes related to IRI in liver, kidney, lung, and heart t
186 ng time from one parent and alleles of major genes related to iron tolerance from the other parent.
188 gnature is characterized by dysregulation of genes related to keratinocyte differentiation and itch s
189 the oxic primary chlorophyll maximum encoded genes related to light and phosphate stress (psbA, psbD
190 and WT plants, and the expression levels of genes related to lignin biosynthesis were significantly
193 art rate, hemocyte levels, and expression of genes related to lipid metabolism, stress, and immunity.
195 omic hypomethylation in AATD liver-impacting genes related to liver cancer, cell cycle, and fibrosis,
198 We also examined genetic polymorphisms in 13 genes related to MeHg metabolism for association with gl
200 interactions with irc6Delta are enriched for genes related to membrane traffic and nuclear processes,
201 identify genomic signatures of selection in genes related to metabolic and signaling pathways that c
203 eurotoxic effects, like the dysregulation of genes related to microtubules, presynaptic vesicle alter
204 s showed that C5aR1 deficiency downregulated genes related to migration/locomotion without changes in
205 analysis revealed differential expression of genes related to mitochondrial and REDOX function in NPC
206 ) transporter genes, but upregulation in the genes related to mitochondrial Ca(2+) efflux pathways, s
207 017 expression leads to higher expression of genes related to mitochondrial stress, cell death/autoph
208 Gene ontology analysis identified a set of genes related to morphogenesis and development (includin
209 ing of PV+INTs revealed several misregulated genes related to morphogenesis, cellular excitability, a
211 in the male barrel cortex, where changes in genes related to morphology, neuronal activity, and neur
212 and found significant expression changes in genes related to motility, maltodextrin metabolism, the
213 ed genes were most significantly enriched in genes related to mRNA and chromosome metabolic processes
217 x that is characterized by downregulation of genes related to neural excitation and synaptic function
219 l importance of DNA methylation variation in genes related to neurodevelopmental and peroxisomal proc
221 KSHV infection upregulates the expression of genes related to neuronal and neuroendocrine (NE) functi
226 ey are characterized with high expression of genes related to Notch signalling, TGFbeta/BMP antagonis
227 that was linked to changes in expression of genes related to nucleosomal regulation of transcription
228 associations between asthma and eQTLs for 4 genes related to nucleotide synthesis/signaling and demo
229 olutionary pressures that may correlate with genes related to nutrient uptake, biofilm formation, or
230 ns were annotated in 11 positional candidate genes related to osteogenesis, skeletal muscle developme
231 t analysis found that these 14 miRNAs target genes related to over 345 different biological pathways.
232 s study revealed EC-specific upregulation of genes related to oxidative phosphorylation (OxPhos).
234 in thousands of genes, most significantly in genes related to pancreas development or function (GATA4
235 EUR) < 0.01), including missense variants in genes related to pancreatic acinar cells (GP2) and insul
236 ent criteria and focusing on the analysis of genes related to pathogenicity and response to stress, w
237 oids showed increment up to 137% and several genes related to PCs biosynthesis and sugar transport we
239 RNA-seq profiling of microglia revealed that genes related to phagocytosis and signaling (IL-6, IL-8,
240 tion of a striking array of genes, including genes related to phagocytosis, metabolism, and retinal d
243 gene expression under FL, including that of genes related to photoprotection, photosynthesis, and ph
244 for black spot and the downregulation of the genes related to photosynthesis and cell wall modificati
245 ral pathogen response to a downregulation of genes related to photosynthesis and cell wall modificati
246 sing profound modulation of transcription of genes related to photosynthesis and other key biological
247 were primarily observed in organelle-encoded genes related to photosynthesis followed by those involv
250 phritis revealed significant upregulation of genes related to PPAR-mediated lipid metabolism and down
251 -seq analyses showed increased expression of genes related to reactive oxygen species, inflammation,
252 d clusters with low- and high- expression of genes related to recurrence of disease; a multivariate C
253 gene B-HOT panel includes the most pertinent genes related to rejection, tolerance, viral infections,
254 type showed a constitutive overexpression of genes related to resistance to myrtle rust caused by A.
264 highlighted biological processes containing genes related to stress adaptation, including the glucoc
265 gi point at a significantly higher number of genes related to stress-tolerance and resource uptake in
266 odeling were identified in the expression of genes related to structure, metabolism, contractility, a
267 k external bark is enriched with upregulated genes related to suberin, which is the main polymer resp
268 his included a higher abundance of expressed genes related to surface attachment in the presence of S
269 fferent time-points, SO and FO downregulated genes related to synthesis and intracellular transport o
270 have significant impacts on copy numbers of genes related to terpene and benzenoid/phenylpropanoid (
271 versity MAGs from Piccard enriched in unique genes related to the cellular membrane, suggesting these
272 y in exons and near splice junctions, and in genes related to the development of the nervous system a
273 ns with rare and common sequence variants in genes related to the enteric nervous system, as well as
274 oinformatic analyses revealed that Oprk1 and genes related to the extracellular matrix (ECM) are impo
276 ide transcriptome analysis demonstrates that genes related to the immune response are repressed by mi
279 resent in the environment, the expression of genes related to the metabolism of alternative carbon so
280 ocused on the expression profiles of the key genes related to the oil metabolisms and hormone regulat
282 , cellular and global expression of specific genes related to the respective processes were examined
284 also observe massive removal of thousands of genes related to the transport process and energy metabo
287 ding tumors showed predominant expression of genes related to tissue repair after treatment, making t
288 nrichment analysis of salt responsive target genes related to top five selected lncRNAs showed their
289 hesized that differential expression of host genes related to translation and innate immune response
290 results in the up-regulation of a number of genes related to transporter activity and membrane funct
292 ption of other TF-encoding genes, as well as genes related to uptake and metabolism of various carboh
295 spaceflight retinas, which were enriched for genes related to visual perception, the phototransductio
296 howed marked differences in the abundance of genes related to vitamin B6 synthesis and branched-chain
297 ction, and respond by altering expression of genes related to Zn uptake, transport and compartmentali
298 n in vitro, with the increased expression of genes related with class-switching and memory B cell dev