ライフサイエンスコーパス: genetic dissection

1 with del22q11 syndrome and the tools for its genetic dissection.

2 that the projection of the BN is amenable to genetic dissection.

3 e receptor diversity in a system amenable to genetic dissection.

4 ught stress in the field is a bottleneck for genetic dissection and breeding of drought resistance.

5 Genetic dissection and expression profiling revealed tha

6 riophages provides opportunities for precise genetic dissection and for numerous phage applications i

7 y neurons in the BNST, which will facilitate genetic dissection and functional studies of BNST subreg

8 on sequencing and genomics tools have led to genetic dissection and identification of potential candi

9 nants in the intracellular life cycle, using genetic dissection and photothermal nanoblade delivery,

10 In this work, we demonstrate, by using genetic dissection and sensitive GC measurements, that t

11 This system will be invaluable for HPV genetic dissection and serves as a faithful ex vivo mode

12 targeting constructs greatly facilitates the genetic dissection and subsequent biochemical investigat

13 By combining behavioral experiments with genetic dissection and ultrastructural analyses, we show

14 h-throughput biochemical assays and directed genetic dissections and emphasizing similarities across

15 pulation of neural circuits often depends on genetic dissection, and use of this technique has been r

16 However, ongoing advances in genomics make genetic dissection attainable in a growing number of spe

17 g autoimmune diseases especially amenable to genetic dissection by genome-wide association studies.

18 Combined chemical/genetic dissection can identify nodal points in developm

19 sitide lipids on TRPV1 function by combining genetic dissection, diet supplementation, and behavioral

20 Although this genetic dissection has provided little information about

21 Genetic dissection has revealed the symbiosis signaling

22 phyll species has been recently described by genetic dissection, however the in vivo role of carotene

23 Using genetic dissection in Drosophila, we show that a Wnt6/EG

24 Pharmacological and genetic dissection in situ and in a heterologous express

25 e, the analysis of the mapped QTLs and their genetic dissection in the US grown Japonica rice genotyp

26 Furthermore, our genetic dissection indicates that FANCM functions with t

27 Genetic dissection indicates that for at least 10 of the

28 raction, through redesign of this domain and genetic dissection into three parts: a protein domain te

29 Moreover, such genetic dissection is essential for the generation of pe

30 Genetic dissection is yielding insights into the molecul

31 ntify disease mechanisms and etiology, their genetic dissection may be assisted by evaluation of link

32 This field is now moving toward a genetic dissection of 3-phosphoinositide action in a var

33 These results indicate that genetic dissection of a complex trait, functional annota

34 Genetic dissection of a genomic region affecting WUE led

35 rful genetic system enabling reliable serial genetic dissection of a large gene family encoding novel

36 ts a novel and relevant system for molecular genetic dissection of a neural circuit that is regulated

37 The genetic dissection of a simple avoidance reaction behavi

38 s, for detecting evolutionary trends and the genetic dissection of adaptive traits.

39 Here, we employ quantitative genetic dissection of an Arabidopsis thaliana developmen

40 rhabditis elegans is a widely used model for genetic dissection of animal behaviors.

41 mediate phenotypes provide crucial tools for genetic dissection of anxiety.

42 This molecular, biochemical, and genetic dissection of ARG function in L. mexicana promas

43 cellular specializations, thus enabling the genetic dissection of auditory processing and hearing di

44 recent new developments in biomechanics and genetic dissection of behavior, and the impact this know

45 non-coding genetic variants in the molecular genetic dissection of brain disorders.

46 data and reverse-genetics resources for the genetic dissection of C. neoformans phenotypes.

47 ves the way for a macrophage-based Mendelian genetic dissection of CD.

48 Here, we present a biochemical and genetic dissection of centralspindlin.

49 rt activity in vivo in a model amenable to a genetic dissection of CHO-1 regulation.

50 The human genetic dissection of clinical phenotypes is complicated

51 model will enable a sophisticated molecular genetic dissection of cold nociceptive genes and circuit

52 provides the foundation for a more complete genetic dissection of collagen type IV molecules and the

53 However, the genetic dissection of complex diseases can be greatly fa

54 single nucleotide polymorphisms (SNPs) allow genetic dissection of complex diseases in a holistic man

55 Sibships are commonly used in genetic dissection of complex diseases, particularly for

56 ls for regenerative therapy will require the genetic dissection of complex regulatory mechanisms gove

57 derived from experimental crosses enable the genetic dissection of complex traits and support modern

58 eity and incomplete penetrance make thorough genetic dissection of complex traits difficult, if not i

59 Thus, genetic dissection of complex traits into specific biobe

60 The genetic dissection of complex traits may ultimately requ

61 lysis of quantitative traits will facilitate genetic dissection of complex traits.

62 tion studies (GWAS) have been widely used in genetic dissection of complex traits.

63 to accelerate breeding and to facilitate the genetic dissection of complex traits.

64 mbinant inbred lines (RILs) designed for the genetic dissection of complex traits.

65 Genetic dissection of complex, polygenic trait variation

66 s, it is now feasible to launch a program of genetic dissection of cortical circuits through systemat

67 tem, with its unparalleled opportunities for genetic dissection of development and functional organiz

68 tions generated by REMI have facilitated the genetic dissection of developmental pathways in Dictyost

69 e an attractive system for the molecular and genetic dissection of developmental pathways in vitro.

70 nogaster is a widely used model organism for genetic dissection of developmental processes.

71 Genetic dissection of disease QTL confidence intervals i

72 n improved strategy that can be used towards genetic dissection of diseases.

73 The genetic dissection of domain function has been stymied i

74 Because redundancy is thought to limit the genetic dissection of early ABA signalling, to identify

75 to generate more molecular tools to enhance genetic dissection of elite African germplasm for improv

76 lupus susceptibility loci will permit future genetic dissection of end-organ susceptibility in murine

77 netic context, opening up the possibility of genetic dissection of epigenetic inheritance.

78 chanisms and set the stage for the molecular genetic dissection of factors underlying such traits.

79 Our genetic dissection of fission yeast CTD function provide

80 The molecular genetic dissection of flowering time control in Arabidop

81 nogenesis in all vertebrates and allow for a genetic dissection of genes needed to establish the earl

82 Genetic dissection of HGF signaling via c-MET reveals th

83 Our genetic dissection of host lipid metabolism identifies a

84 The genetic dissection of hot spots for chromosomal abnormal

85 ures as an important experimental system for genetic dissection of HPV regulatory elements.

86 model systems, for therapeutic screening and genetic dissection of human CNS circuitry.

87 After years of linear gains in the genetic dissection of human disease we are now in a peri

88 Genetic dissection of human systemic lupus erythematosus

89 nderstand complex, non-Mendelian phenotypes, genetic dissection of hypertension-related traits employ

90 cell lines provide a tractable model for the genetic dissection of immunoglobulin hypermutation and t

91 Genetic dissection of important agronomic traits is esse

92 ion of this integrated resource will enhance genetic dissection of important traits and accelerate me

93 DD is a promising intermediate phenotype for genetic dissection of impulsivity and externalizing spec

94 eceptor 3-specific connectome useful for the genetic dissection of inborn errors of Toll-like recepto

95 inical and immunological impact of the human genetic dissection of infectious phenotypes.

96 urate model for KS and open the door for the genetic dissection of KS pathogenesis and evaluation of

97 Genetic dissection of lupus pathogenesis in the NZM2410

98 Genetic dissection of M. tuberculosis is complicated by

99 The genetic dissection of major depressive disorder (MDD) ra

100 nce (UAS)-GAL4 binary system has facilitated genetic dissection of many biological processes in Droso

101 DeepTetrad will accelerate the genetic dissection of mechanisms that control meiotic re

102 interference, these methods will facilitate genetic dissection of meiotic recombination control.

103 nstrate the suitability of the mouse for the genetic dissection of microdeletion syndromes.

104 Our results open the door to genetic dissection of mitochondrial Ca(2+) signaling in

105 vironmental risk factors has complicated the genetic dissection of more prevalent essential hypertens

106 rphogenesis genes, posing a challenge to the genetic dissection of morphogenesis mechanisms.

107 Through genetic dissection of mouse models of PV, we show that t

108 To address these questions, we began a genetic dissection of myelination in zebrafish.

109 in specific cell types is essential for the genetic dissection of neural circuits.

110 The genetic dissection of NIDDM allowed us to map up to six

111 nociception and the power of Drosophila for genetic dissection of nociception.

112 Mobile-CRISPRi enables genetic dissection of non-model bacteria, facilitating a

113 rovide a broadly applicable strategy for the genetic dissection of nuclear export mechanisms and reve

114 lts in a thin eggshell phenotype, allowing a genetic dissection of origin regulation.

115 The genetic dissection of other adaptive traits in Aquilegia

116 e approach developed can also facilitate the genetic dissection of other dynamic processes, including

117 However, the genetic dissection of PARP function has been hindered by

118 and thus should provide an animal model for genetic dissection of pathways contributing to the disea

119 Using pharmacologic and genetic dissection of PI3K/mTOR signaling, dual DDR/mTOR

120 The genetic dissection of PKD allowed us to map on rat chrom

121 The genetic dissection of PKD in the cross allowed us to det

122 ding positional cloning of monogenic traits, genetic dissection of polygenic traits, construction of

123 Our work initiates the genetic dissection of posterior body morphogenesis and l

124 rons through a combined pharamacological and genetic dissection of presynaptic pH homeostatic mechani

125 legans to investigate this question, through genetic dissection of process outgrowth both in vivo and

126 ntitative phenotypes can be used for in vivo genetic dissection of protein mechanism in Arabidopsis.

127 ive trait loci (QTLs) is a powerful tool for genetic dissection of QDR.

128 with luxCDABE should greatly facilitate the genetic dissection of quantitative differences in gene-f

129 ymorphism detection will greatly advance the genetic dissection of quantitative traits in model organ

130 Genetic dissection of regulatory and metabolic attribute

131 ogressive renal failure, suggesting that the genetic dissection of renal failure in humans will requi

132 of RHD3 regulation, we conducted a molecular genetic dissection of RHD3 gene expression and function.

133 a and demonstrated the use of the network in genetic dissection of rice biotic stress responses and i

134 ive phenotyping techniques for more complete genetic dissection of rice dynamic responses to drought

135 nes, provides a solid foundation for further genetic dissection of rubber related traits, comparative

136 D occurring during this period, we undertook genetic dissection of seven currently known Drosophila c

137 Genetic dissection of signaling in model organisms along

138 Genetic dissection of signaling pathways in mammalian ce

139 osophila may serve as a model system for the genetic dissection of sleep.

140 Thus, our studies present a genetic dissection of SLIT/ROBO signaling during organ d

141 me-scale mutant libraries may facilitate the genetic dissection of such complex phenotypes but with l

142 tant role in phenotypic variability, yet the genetic dissection of such phenomena remains challenging

143 e in budding yeast provides a foundation for genetic dissection of the biological functions of SR pro

144 We also provide new data on the genetic dissection of the cell death pathways operative

145 phyla and set the stage for a sophisticated genetic dissection of the cellular and molecular alterat

146 Altogether, this information will allow the genetic dissection of the characters involved in the dom

147 A successful genetic dissection of the circadian regulation of behavi

148 ishes a behavioral paradigm that will enable genetic dissection of the circuits underlying polarizati

149 de heritable quantitative phenotypes for the genetic dissection of the complex condition of atheroscl

150 methods allow pharmacological inhibition and genetic dissection of the determinants of fungal pathoge

151 A genetic dissection of the diabetes syndrome has been car

152 fying loci contributing to BP-I risk and for genetic dissection of the disorder.

153 ironments are not significantly disrupted by genetic dissection of the domains.

154 ts, and provide, to our knowledge, the first genetic dissection of the downstream signaling events in

155 development of diagnostic DNA markers is the genetic dissection of the factors that control resistanc

156 ant Arabidopsis provides many advantages for genetic dissection of the function of this conserved act

157 Here, we present a genetic dissection of the functions of the hemopexin and

158 In addition, further genetic dissection of the genes encoding the predicted m

159 eview is the anticipation that the molecular genetic dissection of the integrated host immune, stress

160 ol of TNF-alpha cytolysis must await further genetic dissection of the introduced Ad genes.

161 This model has made possible a step in the genetic dissection of the learning, behavioral, and neur

162 Here we provide a genetic dissection of the mcm5 gene in Drosophila that d

163 um swarm colonies is an effective method for genetic dissection of the mechanism of light sensing in

164 However, further genetic dissection of the mechanism of this enhanced cyt

165 The genetic dissection of the molecular mechanisms of the C.

166 However, this approach requires genetic dissection of the multiple functions attributed

167 Here, through the genetic dissection of the murine SC, we identify a funct

168 Genetic dissection of the NURF complex using Smarca1, Sm

169 s, and provides the basis for the systematic genetic dissection of the PNS-hematopoietic axis in the

170 ular entry, and it offers the possibility of genetic dissection of the polyamine transport process, i

171 Toward a genetic dissection of the processes involved in aging, a

172 for studying primary cilia in vitro, with a genetic dissection of the protein-protein binding relati

173 The molecular genetic dissection of the QTLs affecting stay-green will

174 Genetic dissection of the regions flanking the bscN gene

175 tion comes a unique opportunity to perform a genetic dissection of the regulation of excitability of

176 hermore, our study is the first to provide a genetic dissection of the relationship between different

177 t strains were created that enabled chemical-genetic dissection of the role of different functional g

178 that this type of screening strategy allows genetic dissection of the roles of various plant defense

179 ity of R. centenum has allowed us to perform genetic dissection of the signaling pathway that affects

180 by a combination of two-hybrid analysis and genetic dissection of the target pathways.

181 ledge, we present the results of a molecular genetic dissection of the TFIID subunit Taf2.

182 als via males, providing the opportunity for genetic dissection of the trait.

183 hase separation, we carried out a systematic genetic dissection of their biosynthetic pathway.

184 The genetic dissection of these interactions presents specia

185 These studies will now allow a genetic dissection of these processes in moss.

186 components of BP psychopathology may enable genetic dissection of this complex disorder, and investi

187 Genetic dissection of this developmental coordination sh

188 dominant sterile hermaphrodites, permitting genetic dissection of this kinase.

189 group level in Drosophila and expect that a genetic dissection of this phenomenon will identify cons

190 osophila Hsp90, setting the stage for future genetic dissection of this phenomenon.

191 A genetic dissection of this problem is afforded by the mi

192 We report in this paper the genetic dissection of this putative operon to determine

193 the CC population can be a powerful tool for genetic dissection of this trait.

194 The genetic dissection of various human infectious diseases

195 a should provide a valuable tool for further genetic dissection of VDAC role(s) in mitochondrial biol

196 time provided the basis for a comprehensive genetic dissection of vertebrate development using the t

197 This human genetic dissection of viral infections is giving rise to

198 Vs with a gain-of -copies and facilitate the genetic dissection of when/where/how the genetic vulnera

199 Genetic dissection of xanthophyll metabolism in the gree

200 To examine the utility of r-cores for genetic dissections of mu1 functions in reovirus entry,

201 onstrate a powerful new system for molecular genetic dissections of sigma1 with respect to its struct

202 Likewise, genetic dissections of the defense response of the nonve

203 This perspective derives both from early "genetic dissections" of learning in mutant Drosophila by

204 Genetic dissections reveal the associations between thes

205 Genetic dissection revealed that recurrent neural circui

206 In addition, such genetic dissection reveals that the super-enhancer conce

207 s for synthesis, recombinant production, and genetic dissection strategies.

208 Here, we used a CRISPR/Cas9 genetic dissection strategy combined with sensitive and

209 imulation, we summarize recent findings from genetic dissection studies conducted in animal models.

210 Here we conducted a cell-specific genetic dissection study in conditional mutant mice that

211 Genetic dissection suggests that Abl functions via Fz/Ds

212 a highly heritable trait which may yield to genetic dissection through use of quantitative trait loc

213 closely related Solanaceae have precluded a genetic dissection, we captured and compared meristem ma

214 Using in vivo recordings and genetic dissection, we identified the DEG/ENaC protein,

215 FACS-sorted cells, single-cell RNA-Seq, and genetic dissection, we identify new blood cell subpopula

216 Through molecular or genetic dissection, we showed that selective editing of

217 This study demonstrates by a complete genetic dissection why the inheritance pattern of S-HSCR

218 often a complex, polygenic trait, making its genetic dissection with traditional genome-wide associat