ライフサイエンスコーパス: genetic locus

1 45, a previously molecularly uncharacterized genetic locus.

2 mologous recombination into the murine mdr1a genetic locus.

3 on mutant and VTC4-1 are alleles of the same genetic locus.

4 (HXGPRT) of the parasite encoded by a single genetic locus.

5 expression within a single cell at a single genetic locus.

6 es with a tumor suppressor, namely the INK4a genetic locus.

7 modulated at the molecular level by a single genetic locus.

8 be confirmed by a test targeting a different genetic locus.

9 hich is known to be associated with the H-2D genetic locus.

10 d in a cluster of genes that occupy a common genetic locus.

11 lies the difficulty in matching the QTL to a genetic locus.

12 logs and are similarly derived from the same genetic locus.

13 of normal and mutant individuals for a given genetic locus.

14 ing to copper (copR), and an uncharacterized genetic locus.

15 ntify a new gene corresponding to the lin-10 genetic locus.

16 at onset, are at least in part determined by genetic locus.

17 phenotypes were due to mutation at the same genetic locus.

18 howed microsatellite instability in a single genetic locus.

19 ng alleles potentially from any heterozygous genetic locus.

20 method for identifying QTLs at the level of genetic locus.

21 re homozygous at an immunologically relevant genetic locus.

22 cifically defined mutations in more than one genetic locus.

23 trains were recessive and mapped to the same genetic locus.

24 includes known alternative variants at each genetic locus.

25 TR of TTP mRNA was deleted in the endogenous genetic locus.

26 sults for mammals are sensitive to choice of genetic locus.

27 latency determinant encoded within the same genetic locus.

28 umbers of subunits all derived from the same genetic locus.

29 to hard or soft selective sweeps at a single genetic locus.

30 due to somatic alterations of the INK4A/ARF genetic locus.

31 (LD) among SNPs, we view each LD block as a genetic locus.

32 of the two roles is determined by a separate genetic locus.

33 (FISH) testing for the amplification of the genetic locus 19q13.42 involving the C19MC cluster of mi

34 roteomic analysis, and NMR, we show that the genetic locus affects the regulation of quorum sensing a

35 idate the relative roles of barrier defects, genetic locus alterations, and environmental exposures i

36 dependent of the Toll-like receptor 4 (tlr4) genetic locus and allelic major histocompatibility compl

37 f containing 8) is located in SCZ-associated genetic locus and is aberrantly expressed in patients wi

38 ese tumors, we have characterized the hRad51 genetic locus and mapped it to chromosome 15q14-15 withi

39 on between DNA sequence variants at the TGFA genetic locus and nonsyndromic oral clefts, 47 studies h

40 sgene were rendered congenic for the Sle1(z) genetic locus and phenotyped for serologic, cellular, an

41 t mechanism for the association between this genetic locus and susceptibility to CAD.

42 rd and Tcra gene segments reside in a single genetic locus and undergo recombination in CD4- CD8- (do

43 ay not represent a single variable site at a genetic locus, and (3) linkage disequilibrium can be use

44 racting species in a community, alleles at a genetic locus, and companies in a market are characteriz

45 umber variations (CNVs) of the human 16p11.2 genetic locus are associated with a range of neurodevelo

46 he full spectrum of genetic risk in the PLB1 genetic locus are warranted.

47 ative methyltransferase, encoded at the same genetic locus as TmaT, is also required for optimal hTMC

48 Here we report a genetic locus associated with a human syndrome of coexis

49 To our knowledge, this is the first genetic locus associated with both cancer risk and WHR.

50 Our results identify a genetic locus associated with estrogen receptor negative

51 A new genetic locus associated with Mycoplasma pneumoniae cyta

52 kinase (DMPK) is the protein product of the genetic locus associated with myotonic dystrophy, in whi

53 This report describes a genetic locus associated with siderophore biosynthesis a

54 ports growth of C. jejuni and identified the genetic locus associated with the utilization of this su

55 e-wide association studies have identified a genetic locus at human chromosome 8q24 as having minor a

56 Thus, we have identified a genetic locus at or near the LPL gene locus which contri

57 lations from Hawaii and Pennsylvania share a genetic locus at which a recessive mutation associated w

58 the need to perform different PCRs for each genetic locus being studied in an ancient DNA extract.

59 gene segments are organized within a single genetic locus but are differentially regulated during T

60 : Many traits are controlled not by a single genetic locus but instead by polymorphisms throughout th

61 d MGC29643 transcripts derived from the same genetic locus but transcribed in opposite directions.

62 scriminating power of HRM + SVM for a single genetic locus by testing longer amplicons harboring sign

63 ected individuals has suggested that a major genetic locus can account for the disorder in some famil

64 sults show that even a single nonrecombining genetic locus can provide substantial power to test the

65 Both of these defects were due to a single genetic locus carrying a Tn5 insertion.

66 e response regulators encoded within its own genetic locus (CheY(1), CheY(2), and CheY(5)) and CheY(3

67 F receptor null mutant mice, we discovered a genetic locus, closely linked to the TNF p55 receptor (T

68 rons and was localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cance

69 ancy because biallelic mutations at a single genetic locus confer all features that define cancer upo

70 However, here, we provide evidence that the genetic locus containing one such gene, BHLF1, indeed co

71 tokine encoded in a functionally polymorphic genetic locus, contributes to detrimental inflammation b

72 red mouse strains demonstrated that a single genetic locus controlled responsiveness to LPS.

73 lic to aconidiate-2, a previously identified genetic locus controlling conidiation.

74 lE) represent the 3' end of a newly reported genetic locus (cyl) required for GBS haemolysin/cytolysi

75 S3007 and within a 17-cM region flanking the genetic locus D4S2366.

76 eins and that mutations at the corresponding genetic locus daf-5 confer defects in DAF-7/TGF-beta sig

77 S886 and D19S894, and have established a new genetic locus designated SCA26.

78 of this paper is to report the linkage of a genetic locus (designated "HBM") in the human genome to

79 a signal sequence led to the discovery of a genetic locus, designated 2.9, which appears to be prese

80 These data functionally define a novel genetic locus, designated PAC1, for prostate adenocarcin

81 of high-reticuline poppy mutants revealed a genetic locus, designated STORR [(S)- to (R)-reticuline]

82 Subcloning and mutagenesis defined a genetic locus, designated zmaR, on a 1.2-kb fragment of

83 nge of mapped and anchored object types with genetic locus details, such as numbers, types and names

84 Our findings indicate that a single genetic locus determines host specificity in this bacter

85 encoding gene couch potato (cpo) as a major genetic locus determining diapause phenotype in D. melan

86 We previously identified a genetic locus, Diet1, which is responsible for the resis

87 a dominantly acting mutation that disrupts a genetic locus distinct from the ADPKD loci, PKD1 and PKD

88 genome, including information by isotype and genetic locus, easily downloadable primary sequences, gr

89 Of particular interest was genetic locus EF1809, predicted to encode a regulatory p

90 nt this problem, we have chosen to clone the genetic locus encoding a mammalian GDP-D-mannose-4,6-deh

91 sis and a screen for loss of cytotoxicity, a genetic locus encoding an RTX toxin system was identifie

92 re is directed by the specific sequence of a genetic locus encoding enzymes directing one of four alt

93 of pathogenic E. coli contain elements of a genetic locus encoding ETT2, but which has undergone sig

94 We propose a likely genetic locus encoding synthesis of the anionic polymer

95 at homozygous deletion involving CDKN2A (the genetic locus encoding the cyclin-dependent kinase inhib

96 an independent discovery and extension of a genetic locus encoding the GBS beta-haemolysin/cytolysin

97 By deleting the genetic locus encoding the regulatory B1 subunit of calc

98 train DH5 alpha with plasmids containing the genetic locus encoding this protein gave rise to E. coli

99 eripherin as orthologs (products of the same genetic locus, evolving separately only since the specie

100 strains contain copies of losA and losB in a genetic locus flanked by infA and ksgA.

101 A genetic locus for a cytolethal distending toxin (CDT) wa

102 These findings thus identify a novel genetic locus for a neurodevelopmental disorder and high

103 autosomal recessive trait and define a novel genetic locus for AF on chromosome 5p13 (arAF1).

104 We sought to identify the genetic locus for an inherited form of dilated cardiomyo

105 verse K277R mutation, establishing RT as the genetic locus for aptamer-mediated HIV-1 inhibition.

106 viduals demonstrates that there is no single genetic locus for AR-DC.

107 The most significantly associated genetic locus for atrial fibrillation (AF) is in chromos

108 We identified a genetic locus for autosomal-recessive nonsyndromic intel

109 overlaps the critical region for the fourth genetic locus for Bardet-Biedl syndrome (BBS4) in humans

110 n chromosome 12p11.2, which falls within the genetic locus for congenital fibrosis of the extraocular

111 It also suggests a novel genetic locus for corneal dystrophy and enamel hypominer

112 ally regarded as a heritable disorder, yet a genetic locus for familial AF was previously mapped to c

113 A genetic locus for FJP has not yet been identified by lin

114 ember subset of this family to determine the genetic locus for HP.

115 The genetic locus for HSAN I has been mapped to chromosome 9

116 RS when it occurs in isolation, and only one genetic locus for isolated DRS, the DURS2 locus on chrom

117 The refinement of the genetic locus for multiple cutaneous and uterine leiomyo

118 is family is linked to the recently reported genetic locus for multiple cutaneous and uterine leiomyo

119 to refine substantially the location of the genetic locus for multiple cutaneous and uterine leiomyo

120 A genetic locus for mutations associated with dilated card

121 In previous efforts to identify the genetic locus for prcd, the canine homologs for many of

122 a highly heritable trait, identifies a novel genetic locus for RLS, and will facilitate further cloni

123 Our observations suggest that there is a genetic locus for social cognition, which is imprinted a

124 We have studied INS VNTR as a candidate genetic locus for susceptibility to PCOS.

125 The genetic locus for SVD lies in a 9 Mb region flanked by D

126 A genome-wide scan previously localized the genetic locus for SVD to a 20 Mb region flanked by D2S21

127 Previously we mapped the genetic locus for the triad of autosomal recessive ARVC,

128 The genetic locus for the TrkC/neurotrophin 3 (NT-3) recepto

129 The genetic locus for this retinal dystrophy has been mapped

130 ouse macrophages, which are deficient in the genetic locus for TLR4, was absent.

131 Among Hispanics, we identified a genetic locus for upper-lower lobe ratio near the alpha-

132 The genetic locus for Vi antigen production is also present

133 In humans, DCX is a major genetic locus for X-linked lissencephaly.

134 A genetic locus from Campylobacter jejuni 81-176 (O:23, 36

135 that allow for the transposition of a single genetic locus from one position on a chromosome to anoth

136 llowed the identification of a newly defined genetic locus, fxsA.

137 We report identification of a novel genetic locus (GLC1P) for normal tension glaucoma (NTG)

138 s the first genome-scan report to identify a genetic locus harboring a gout-susceptibility gene.

139 To our knowledge, this is the first time a genetic locus has been shown to influence motor progress

140 There was clear evidence for genetic locus heterogeneity upon examination of ten addi

141 Significant evidence for genetic locus heterogeneity was observed, with similar e

142 atients into subgroups relative to suspected genetic locus heterogeneity.

143 on of these disorders, some of which display genetic (locus) heterogeneity.

144 port the discovery of an approximately 16-kb genetic locus, HiGI1, that is present primarily in type

145 s study, we report the characterization of a genetic locus, HOS2, which is defined by three Arabidops

146 FCD2, at 18q21, is the second genetic locus identified for late-onset FCD.

147 norhabditis elegans gene rec-1 was the first genetic locus identified in metazoa to affect the distri

148 performed the first mutational analysis of a genetic locus immediately upstream of the streptolysin S

149 ndings suggest that modification of a second genetic locus in a defined neurodevelopmental regulatory

150 ilar in length to O3L were found at the same genetic locus in all vertebrate poxviruses.

151 We report the identification of a large genetic locus in B. bronchiseptica and B. parapertussis

152 These results identify a novel genetic locus in BALB/cJ mice that confers resistance to

153 These variants are encoded by the same genetic locus in diverse strains and have nearly identic

154 the transgene was integrated at a different genetic locus in each animal and was transmitted to appr

155 us Control Region by integrating at the same genetic locus in MEL cells, a LacZ gene driven by the hu

156 pondylitis, the MHC was the major permissive genetic locus in murine PG-induced spondylitis (PGIS).

157 b apart and may have appeared to be a single genetic locus in some sorghum populations.

158 eening revealed a broad distribution of this genetic locus in strains derived from various host speci

159 Using subcongenic mice, we found that a genetic locus in the 88-96 cM region was associated with

160 h, and confirm the importance of the LUCA-15 genetic locus in the control of apoptosis.

161 Here, Lee et al. identify a genetic locus in the nematode Caenorhabditis elegans tha

162 The discovery of a novel genetic locus in this family provides more evidence that

163 Identification of the responsible genetic locus in those mutants significantly extends our

164 compelling evidence for an involvement of a genetic locus includes linkage, we tested a candidate re

165 HK and RR trees with proteins from the same genetic locus indicated.

166 In conclusion, we identified a major genetic locus influencing BMI on chromosome 4p in Mexica

167 For each genetic locus, information about marker type or contig c

168 common polymorphism at the haptoglobin (Hp) genetic locus is associated with CVD, especially coronar

169 A single genetic locus is assumed to control fertility, and this

170 y affected, large families in which a single genetic locus is probably responsible for conferring sus

171 We describe here the first genetic locus isolated using these criteria: crooked leg

172 secretion pathway are clustered at the same genetic locus, known as RD1.

173 We have identified and characterized a genetic locus lic that is required for phosphorylcholine

174 Its restricted cellular distribution and genetic locus make it a candidate gene for the inherited

175 mmediately identifying the YACs containing a genetic locus mapped on Arabidopsis chromosome 2.

176 These findings suggest that this genetic locus may have an important impact on male ferti

177 The UCP2/UCP3 genetic locus may play a role in childhood body weight.

178 g autozygosity mapping, we have identified a genetic locus (MCPH1) for primary microcephaly, at chrom

179 Our previous study identified a new genetic locus, mrp, which is required for both fruiting

180 ral assays and linkage mapping to identify a genetic locus (nict-1) that mediates the phoretic intera

181 A genetic locus (no greater than 4.96 Mb in size) at Xp11.

182 have previously functionally defined a novel genetic locus nonpapillary renal carcinoma-1 (NRC-1) wit

183 ge studies demonstrate that nm1054 maps to a genetic locus not previously implicated in microcytic an

184 thway to tumorigenesis in the kidney via the genetic locus NRC-1.

185 c approach, we previously identified a novel genetic locus, NRC-1 (Nonpapillary Renal Cell Carcinoma

186 fiber genes are recombined into the natural genetic locus of adenovirus through unidirectional Cre-l

187 m of obese and diabetic individuals, and the genetic locus of adiponectin is linked to the metabolic

188 The wlb genetic locus of B. pertussis has been previously descri

189 The entire diffocin genetic locus of more than 20 kb was cloned and expresse

190 A genetic locus of Pseudomonas aeruginosa was identified t

191 and antidepressant drug action, is a common genetic locus of risk for mental illnesses, and remains

192 C transporter complex, which is encoded by a genetic locus of the EAEC virulence plasmid pAA2.

193 Based on treatment history and genetic locus of the sequence changes, 39 of the sequenc

194 We have identified the genetic locus of these "diffocins" (open reading frames

195 enuated in a semidominant fashion by a major genetic locus on chromosome (Chr) 13.

196 In so doing, we have identified a genetic locus on chromosome 1 shared by all affected ind

197 16 introgression lines identified a dominant genetic locus on chromosome 5 from the wild relative tha

198 ce on a working memory task and identified a genetic locus on chromosome 5 that contributes to a subs

199 These data define and map a genetic locus on human chromosome 2 that extinguishes al

200 Previously we mapped a new genetic locus on mouse chromosome 1, designated sst1 (fo

201 Our results demonstrate that a genetic locus on rat chromosome 3, HR-SP1, contributes d

202 Chromosome 19q likely contains a genetic locus (or loci) that influences COPD through an

203 Our findings represent the first genetic locus outside of LOXL1 surpassing genome-wide si

204 of losses and gains of the tumor suppressor genetic locus p16(INK4A).

205 This report identifies a genetic locus physically and functionally linked to type

206 timing of transcriptional activation and the genetic locus play important roles in determining the fu

207 One additional genetic locus previously linked to psychosis in Alzheime

208 Searches can be conducted for genetic locus, probe or sequence accession number; searc

209 A single genetic locus produces two transcripts, TgFPPS and TgFPP

210 signed to chromosome 5p15, the location of a genetic locus (PROP) that controls the detection of the

211 h root hair length and was associated with a genetic locus (QTL) on chromosome 2H.

212 mutants is mediated in part by agr RNAIII, a genetic locus regulated by mgrA.

213 cate that the previously identified specific genetic locus regulating strain-dependent collateral ves

214 Furthermore, our studies identify the first genetic locus regulating the orientation of cell divisio

215 conserved throughout the Actinobacteria in a genetic locus related to cell wall synthesis and cell di

216 The genetic locus required for cable pilus biogenesis is com

217 transposon mutagenesis we have identified a genetic locus required for the biosynthesis of LPS in B.

218 d which shows the presence or absence of the genetic locus required for Vi expression.

219 We also narrowed the genetic locus responsible for citrus polyembryony, a for

220 ication of the gene for BHD may reveal a new genetic locus responsible for renal neoplasia and for lu

221 se results suggest that AS3MT is the primary genetic locus responsible for the unique pattern of iAs

222 The genetic locus responsible for this natural variant, VICT

223 The genetic locus responsible for this phenotype in FA19 was

224 We have defined the genetic locus responsible for ultraviolet B susceptibili

225 The SAP gene has been identified as the genetic locus responsible for X-linked lymphoproliferati

226 phism segregate as if controlled by a single genetic locus, resulting from tight genetic linkage betw

227 We report a NK complex-linked genetic locus, Rhs1, whose alleles influence the magnitu

228 d, each gene group is tested for a causative genetic locus shared with the clinical trait of interest

229 Here, we describe a new genetic locus, SIAMESE (SIM), required for coordinating

230 We have previously identified an NZM2410 genetic locus, Sle2, which is associated with the produc

231 In the majority of AT/RT, LOH occurs at the genetic locus SNF5 (Ini1/BAF47/Smarcb1), which functions

232 Three forms of a single genetic locus specify this species' three mating types:

233 bacterium tuberculosis, we have identified a genetic locus sst1 on mouse chromosome 1, which controls

234 terium tuberculosis (Mtb), we identified the genetic locus sst1 that controls the progression of pulm

235 rd gene segments are organized into a single genetic locus (Tcra/Tcrd locus) that undergoes V(D)J rec

236 ruginosa strain ZK2870 and identify a second genetic locus, termed psl, involved in the production of

237 ino acid 180 of the GCD1 gene product as the genetic locus that allows translational regulation upon

238 These results show that a narrow genetic locus that contains Csnk1e is associated with di

239 units (AccD1 to -6), with accD6 located in a genetic locus that contains members of the FAS II comple

240 Rhg4 is a major genetic locus that contributes to soybean cyst nematode

241 Suppose there is one genetic locus that controls the capacity to internalize

242 is located at or near the mouse Sac locus, a genetic locus that controls the detection of certain swe

243 phoA insertion maps to a recently identified genetic locus that encodes products that are predicted t

244 Rcr3 and Pip1 reside on a genetic locus that evolved over 36 million years ago.

245 Our data show that the same genetic locus that has been identified as a marker for t

246 This is the first genetic locus that has been shown to influence the risk

247 The finding of a genetic locus that has extensive effects on neuronal dev

248 Taken together, our results identify a genetic locus that influences enamel structure and estab

249 suggests the existence of a third, unlinked genetic locus that influences the interaction between Cr

250 l of islet cell carcinogenesis to identify a genetic locus that influences tumor progression to an in

251 HLA, this is the strongest evidence yet of a genetic locus that is both linked to and associated with

252 which in mouse is tightly linked to the SOA genetic locus that is involved in detecting the bitter c

253 lity that MCD type II may be due to the same genetic locus that is involved in MCD type I.

254 th ALS and FTD or either ALS or FTD alone, a genetic locus that is linked to ALS with FTD located bet

255 cterization of a transgenic mouse revealed a genetic locus that is specifically regulated in T cells.

256 gastric Le phenotype, and reveal a bacterial genetic locus that is subject to host-driven selection p

257 e expressed from what appears to be a single genetic locus that largely coincides with an approximate

258 he B. hermsii gene encoding FhbA is a single genetic locus that maps to a linear plasmid of approxima

259 In addition, we have mapped a genetic locus that may be responsible for the LTNP trait

260 m; P=0.03), suggesting some effect from a BS genetic locus that modifies hypertrophy induced by the c

261 ice and suggest that mouse Chr. 4 contains a genetic locus that modulates the mechanosensitivity of b

262 The centromere is the genetic locus that organizes the proteinaceous kinetocho

263 these strains were two with disruptions in a genetic locus that putatively codes for a transcriptiona

264 LepB is positioned within a genetic locus that resembles the locus containing the ex

265 viously based on evidence from only a single genetic locus that this species may be either the closes

266 died patients is due to a defect in the same genetic locus that underlies the cancer-prone genetic di

267 We report here the identification of a genetic locus that, when mutated, results in a precociou

268 We named this genetic locus the commensal colonization factors (ccf).

269 ly reported association of RA with the PTPRC genetic locus, the present study was undertaken to test

270 We have named the mutant alleles and the genetic locus they define brachyenteron (byn); phenotypi

271 FCD1 is the first genetic locus to be identified for late-onset FCD, a com

272 th congenital TTP and mapped the responsible genetic locus to chromosome 9q34.

273 However, the only bona fide genetic locus to emerge from extensive analysis of CMM s

274 o insert genes at a previously characterized genetic locus to make plant transformation and transgene

275 present here an inducible system to target a genetic locus to the nuclear lamina in living mammalian

276 n mice, highlighting the STPP as a potential genetic locus underlying interindividual differences in

277 The genetic locus underlying this phenotype was mapped to ni

278 In this report, we characterize a genetic locus unique to staphylococci called rsr that ha

279 The only genetic locus universally accepted to be important as a

280 ort here that I/LnJ mice carry an additional genetic locus, virus infectivity controller 2 (vic2), th

281 or the less restrictive phenotype of CAD, no genetic locus was detected, suggesting that CAD and MI m

282 s jannaschii was purified and sequenced: its genetic locus was found to correspond to gene MJ0626.

283 In the same genetic locus, we also identified a two-component system

284 ented the most significant variation in this genetic locus were assessed.

285 ozygous for B6 markers of this chromosome 11 genetic locus were, respectively, highly susceptible or

286 tern, suggesting the involvement of a single genetic locus, which has been named TOX2.

287 Genetic association studies indicate that a genetic locus, which includes the CHRNA5-CHRNA3-CHRNB4 g

288 This genetic locus, which we have named mustard (mtd), contai

289 Children with risk alleles at the 17q21 genetic locus who wheeze during rhinovirus illnesses hav

290 Thus, the two bin2 mutations define a novel genetic locus whose gene product might play a role in BR

291 ultrasound/DXA measures and points to a new genetic locus with potential implications for better und

292 Treponema denticola harbours a genetic locus with significant homology to most of the p

293 SidE enzymes share the genetic locus with the Legionella effector SidJ that spa

294 rc, these alleles show that crc is a complex genetic locus with two overlapping lethal complementatio

295 report the functional definition of a novel genetic locus within human chromosome 10pter-q11 that me

296 A specific genetic locus within pgm, which shares similarity to a p

297 We previously described a novel genetic locus within the ULb' region of the human cytome

298 We describe a novel genetic locus, wunen (wun), required for guidance of ger

299 Here we report a new genetic locus, XLIS, mapped by linkage analysis of five

300 ationale for the designation of the previous genetic locus ybdA as entS to reflect its relevant biolo