ライフサイエンスコーパス: genetic predisposition

1 ates for mutations were calculated to assess genetic predisposition.

2 , and lack of exercise, but it also involves genetic predisposition.

3 ssociation that is likely to be moderated by genetic predisposition.

4 roportion of young CRC cases associated with genetic predisposition.

5 44 of 153 patients (29%) had an identifiable genetic predisposition.

6 d nonallergic reactions (NARs) influenced by genetic predisposition.

7 combined effects of an exogenous trigger and genetic predisposition.

8 matory-related precursors on a background of genetic predisposition.

9 its in populations with a known or suspected genetic predisposition.

10 iduals whose cancers arise in the setting of genetic predisposition.

11 d properties, gut microbiota, and individual genetic predisposition.

12 f a cell to its environment as a function of genetic predisposition.

13 pulations, such as TH17 cells, influenced by genetic predisposition.

14 rarely elsewhere in the world, suggesting a genetic predisposition.

15 , and they are thought to be associated with genetic predisposition.

16 f consuming SSBs owing to their ethnicity or genetic predisposition.

17 g ER (ER positive), including differences in genetic predisposition.

18 indicating sporadic IPF occurs in those with genetic predisposition.

19 Hmong affected are unclear, but may involve genetic predisposition.

20 should consider age, training intensity, and genetic predisposition.

21 ial background, which would be evidence of a genetic predisposition.

22 RA and GPA may arise from a similar genetic predisposition.

23 ring care tailored to individual patterns of genetic predisposition.

24 ncies without a known (or as-yet-identified) genetic predisposition.

25 n sensitivity analyses that suggested shared genetic predisposition.

26 hese tissues for mapping psychiatric disease genetic predisposition.

27 is more frequently associated with germline genetic predisposition.

28 heir supportive environment based upon their genetic predispositions.

29 so differ between individuals with different genetic predispositions.

30 ntal experiences, or does this interact with genetic predisposition?

31 Genetic predisposition accelerates the trajectory.

32 Genetic predisposition accounts for 5 to 10% of cancer d

33 Genetic predisposition accounts for most of the risk of

34 and involves a variety of factors, including genetic predisposition, acute injury and chronic inflamm

35 Genetic predisposition affects the penetrance of tumor-i

36 attributed to a number of factors, including genetic predisposition, age and different environmental

37 ans have been studying risk factors, such as genetic predisposition, aging, obesity, and joint malali

38 s were combined in 4 scores as indicators of genetic predisposition; all SNPs in a general score and

39 inflammatory and autoimmune mechanisms, and genetic predisposition also interplay in the disease ass

40 tal regions, suggesting a mechanism by which genetic predisposition alters reward processing not only

41 rise, at least in part, from a glutamatergic genetic predisposition and a deficit in short-term habit

42 is believed to arise from an interaction of genetic predisposition and adverse environmental factors

43 ld be seen as the result of a combination of genetic predisposition and an immune-mediated two-hit mo

44 Differences in the incidence of genetic predisposition and clinical presentation of sinu

45 eloping atrial fibrillation (AF) considering genetic predisposition and clinical risk factor burden i

46 It is clear that the interaction between genetic predisposition and early life environmental expo

47 ity is the consequence of the combination of genetic predisposition and environmental effects, such a

48 is driven by a complex relationship between genetic predisposition and environmental exposures.

49 disease, resulting from cellular senescence, genetic predisposition and environmental factors (e.g. n

50 ve several causal pathways, including common genetic predisposition and environmental factors, and in

51 se that results from the interaction between genetic predisposition and environmental factors.

52 ing disease that arises on the background of genetic predisposition and environmental risk factors, s

53 nknown but postulated to be a combination of genetic predisposition and environmental triggers.

54 ized to be a result of the interplay between genetic predisposition and increased vulnerability to ea

55 our data indicated that associations between genetic predisposition and obesity traits were stronger

56 ompartment establishes a formal link between genetic predisposition and skin inflammation observed in

57 We analyzed the interaction between genetic predisposition and the intake of sugar-sweetened

58 CPCs derived from aged patients with HF with genetic predispositions and comorbidities of chronic dis

59 pB-ALLs) caused by a combination of prenatal genetic predispositions and oncogenic events occurring a

60 k factors (such as obesity, tobacco use, and genetic predisposition) and HIV-specific and ART-specifi

61 y include lifestyle factors such as smoking, genetic predisposition, and specific comorbidities such

62 reoperative evaluation of patients including genetic predisposition, appear to provide initial opport

63 Poor metabolic control and host genetic predisposition are critical for diabetic kidney

64 and anatomy, dietary composition, housing or genetic predisposition are discussed in this paper.

65 Ethnicity and genetic predisposition are partly responsible for this h

66 Smoking, drinking alcohol, and genetic predisposition are the major risk factors for ch

67 Although genetic predispositions are frequent in children (>1% to

68 Two genetic predispositions are particularly crucial.

69 Confirmation of genetic predisposition, as defined by reproducibility an

70 Although genetic predisposition can play a substantial role, our

71 idea that matching instruction to individual genetic predispositions can enhance learning.

72 nd the ubiquitin-binding protein, p62, has a genetic predisposition component in humans and mice.

73 cancer treated with lumpectomy regardless of genetic predisposition; contralateral annual mammogram m

74 ar evidence that environmental exposures and genetic predisposition contribute to the pathogenesis of

75 ll carcinoma (RCC) have been identified, yet genetic predisposition contributes significantly to this

76 wing researchers to determine how underlying genetic predisposition contributes to human disease.

77 individual differences in learning styles or genetic predispositions could improve learning outcomes.

78 We hypothesized that germline genetic predispositions differ between African Americans

79 ucoma worldwide, is a systemic disorder with genetic predisposition due to variations in lysyl oxidas

80 ates of sleep loss at night and propose that genetic predisposition entails differential cerebral cop

81 se is a multifactorial process that includes genetic predisposition, environmental adjuvant factors,

82 such as diabetes, and/or the interaction of genetic predisposition, environmental insults, and age.

83 These changes may be due to genetic predisposition, environmental perturbations, med

84 ad connections and interdependencies between genetic predisposition, environmental perturbations, reg

85 ns unclear, although studies have implicated genetic predispositions, environmental risk factors, and

86 ophysiology is complex and involves a strong genetic predisposition, epidermal dysfunction, and T-cel

87 udies are ideal to investigate the effect of genetic predisposition, epigenetics, and environmental e

88 he pathogenesis is multifactorial, involving genetic predisposition, epithelial barrier defects, dysr

89 Although genetic predisposition establishes susceptibility, rapid

90 t contradict the data obtained on a possible genetic predisposition, even in sporadic or non-heredita

91 of ALL and highlight a possible link between genetic predisposition factors in the pathogenesis of au

92 SVMR showed genetic predisposition for alcohol consumption to be ass

93 Our findings identify that a genetic predisposition for autism is associated with adv

94 In this study we investigated if a genetic predisposition for autism is associated with chi

95 decrease in LDL-C on average than those with genetic predisposition for average LDL-C.

96 and BRCA2 gene mutations have an underlying genetic predisposition for breast and ovarian cancers.

97 g will meet the challenge of elucidating the genetic predisposition for common polygenic diseases, es

98 Together, this supports the possibility that genetic predisposition for complex disease is manifested

99 variants in RTEL1 represent a newly defined genetic predisposition for FIP, supporting the importanc

100 For example, individuals with genetic predisposition for higher LDL-C had a lesser dec

101 A genetic predisposition for HLH was not identified in any

102 This is the first study to show that greater genetic predisposition for MS is associated with higher

103 especially when accompanied by a heightened genetic predisposition for response to physical exercise

104 BD patients suggest a differential effect of genetic predisposition for SZ versus BD on the developme

105 irst-degree relatives, possibly representing genetic predisposition for these disorders.

106 FD-induced obesity, the hPXR mouse carries a genetic predisposition for type 2 diabetes and thus prov

107 n VR-PAH, suggesting a potentially different genetic predisposition for VR-PAH.

108 nation, including moderating factors such as genetic predisposition, habitual caffeine intake, and ca

109 As the importance of genetic predisposition has been firmly established in th

110 Even though genetic predisposition has proven to be an important ele

111 d spots are a common skin aging feature, but genetic predisposition has yet to be thoroughly investig

112 nce that the risk and course of HF depend on genetic predisposition; however, the genetic contributio

113 Risk factors for AF include age, male sex, genetic predisposition, hypertension, diabetes mellitus,

114 clinically meaningful improvements, and that genetic predisposition impacts clinical responses to lif

115 Here we studied genetic predisposition in a family with six affected ind

116 his explains a substantial proportion of the genetic predisposition in African- and Hispanic-American

117 A role for a genetic predisposition in diverticulitis is suggested by

118 Nevertheless, the genetic predisposition in many families with multi-incid

119 ht and obesity over time are associated with genetic predisposition in the context of an obesogenic e

120 apped shared chromosomal regions to identify genetic predisposition in the family.

121 Obesity, tobacco smoking, and genetic predisposition increase the risk of developing G

122 Thus, there is a genetic predisposition inherent in B-1 development gener

123 elopment of mirror mechanisms are discussed: Genetic predispositions interact with associative learni

124 the intersection and interactions between a genetic predisposition involving the BMPR2 signaling pat

125 eness is one of the mechanisms through which genetic predisposition leads to weight gain in an enviro

126 cent evidence indicates that, in addition to genetic predisposition, lifestyle changes owing to moder

127 Genetic predisposition mainly arises from mutations on t

128 rrier function is disrupted by, for example, genetic predisposition, mechanical damage, or the enzyma

129 Genetic predisposition might affect neurodevelopmental o

130 Pathological obesity can result from genetic predisposition, obesogenic diet, and circadian r

131 and addressed two questions, (1) whether the genetic predisposition of nicotine dependence influence

132 We found the genetic predisposition of nicotine dependence was associ

133 We investigated a genetic predisposition of the CAV-1 gene on survival, ac

134 nt patterns depending both on vaccine Ag and genetic predisposition of the vaccinee.

135 associated secretory phenotype, indicating a genetic predisposition of these mice to increased carcin

136 d very little is known about the etiology or genetic predisposition of this condition.

137 mined the role of maternal farm exposure and genetic predisposition on TH17 cell responses to innate

138 nteractions between diet, DNMT-1 levels, and genetic predisposition on the development and severity o

139 however, little is known about the impact of genetic predisposition on the response to lifestyle coac

140 on 55 clinical markers and 2) the effect of genetic predisposition on these clinical changes.

141 An unrecognized genetic predisposition or altered gut permeability causi

142 er hypermutant cancers arising from primary (genetic predisposition) or secondary MMRD.

143 with familial history, chronic diseases with genetic predispositions, or inherited cancer syndromes,

144 This parallels enrichment of prostate cancer genetic predispositions over these transcription regulat

145 ated with later AF onset after adjusting for genetic predisposition (P<0.001).

146 Our data suggest that prenatal exposures and genetic predisposition play a role during early TH17 imm

147 While aging and inherent genetic predisposition play major roles in the onset of

148 We could show that the genetic predisposition provided by the NOD background wa

149 plex with multiple risk factors and a strong genetic predisposition rather than a condition with a si

150 also raise the possibility of an impact from genetic predispositions related to oxidative stress and

151 ctly without necessarily going through human genetic predispositions, resulting in inter-specific gen

152 show that superimposition of inflammation on genetic predisposition results in high incidence of pret

153 n scores (GRSs) were constructed: a complete genetic predisposition score including all 50 single nuc

154 le nucleotide polymorphisms (GRSComplete), a genetic predisposition score including BMI-associated si

155 ngle nucleotide polymorphisms (GRSWC), and a genetic predisposition score including the waist-to-hip

156 single nucleotide polymorphisms (GRSBMI), a genetic predisposition score including waist circumferen

157 The genetic predisposition score showed consistent associati

158 A genetic predisposition score was calculated on the basis

159 The genetic-predisposition score was calculated on the basis

160 o adjusted for BMI (WHRBMI), the following 4 genetic predisposition scores (GRSs) were constructed: a

161 r concerning UV exposure is complicated by a genetic predisposition shared with neuropsychological tr

162 Sexual differences in genetic predisposition should be considered in future st

163 A genetic predisposition, smoking, obesity and hormonal fa

164 Genetic predispositions strongly contribute to the devel

165 that has happened in historical times and a genetic predisposition that has its origins in our evolu

166 e first platelet function-related CpG-SNP, a genetic predisposition that reinforces PEAR1 enhancer ac

167 ings reflect the clinical association of the genetic predisposition that was recently confirmed in a

168 on a number of different factors, including genetic predisposition, the number and releasability of

169 osition gene and increased the prevalence of genetic predisposition to 40% among paediatric patients

170 in analyses of the DeltaWCBMI CONCLUSIONS: A genetic predisposition to a high WC may attenuate the as

171 The study findings of genetic predisposition to A(H7N9) in the Chinese populat

172 score for WHR adjusted for BMI, a measure of genetic predisposition to abdominal adiposity, was const

173 These results suggest that genetic predisposition to acrophobia in this genetic iso

174 e earliest brain changes associated with the genetic predisposition to AD.

175 Results indicate that genetic predisposition to ADHD does not increase the ris

176 ng focus on the interaction between diet and genetic predisposition to adiposity, studies should cons

177 c histone deacetylase (HDAC) isoforms in the genetic predisposition to anxiety and alcoholism is unkn

178 In addition to asbestos exposure, genetic predisposition to asbestos carcinogenesis and to

179 t interactions and that in the presence of a genetic predisposition to ASD, diet can make a large dif

180 The mechanism is unknown, and genetic predisposition to asparaginase-induced pancreati

181 These data indicate that in the absence of genetic predisposition to autoimmunity, loss of endogeno

182 ive control of emotion are implicated in the genetic predisposition to bipolar disorder, with aberran

183 Pathways involved in the genetic predisposition to BP include hormonal regulation

184 The association between a genetic predisposition to breast cancer (using PRS) and

185 y, we investigated the association between a genetic predisposition to breast cancer and mammographic

186 indings provide an improved understanding of genetic predisposition to breast cancer subtypes and wil

187 e and begin to unravel common aspects in the genetic predisposition to bronchopulmonary dysplasia, br

188 Therefore, a genetic predisposition to build strong memories could le

189 type, oxidation of phospholipids, Lp(a), and genetic predisposition to CAD and cardiovascular events.

190 Increased genetic predisposition to CAD was inversely associated w

191 ion and outcomes of population screening for genetic predisposition to cancer in other populations.

192 We adopted the HLA-B *1502 genetic predisposition to carbamazepine (CBZ)-induced St

193 one novel gene (NDUFB9) associated with the genetic predisposition to CD in African-Americans.

194 Recent studies have suggested a possible genetic predisposition to CH.

195 Overall, we did not find a genetic predisposition to CHIP mutations in this twin st

196 studies have provided evidence for inherited genetic predisposition to chronic lymphocytic leukemia (

197 Some evidence suggests a genetic predisposition to chronic venous disease from ge

198 BACKGROUND & AIMS: Although there is a genetic predisposition to colorectal cancer (CRC), few o

199 The importance of genetic predisposition to coronary artery disease and my

200 ay be further exacerbated among persons with genetic predisposition to coronary artery disease.

201 of sleep to MI and its potential to mitigate genetic predisposition to coronary disease is unclear.

202 llular matrix architecture contribute to the genetic predisposition to CTS by altering the environmen

203 nisms that cause AF in patients, including a genetic predisposition to develop AF.

204 in vivo evidence of an underlying germ-line genetic predisposition to developing this disorder.

205 We investigated whether a genetic predisposition to developmental disorders was as

206 rminants of risk of SRCC in individuals with genetic predisposition to DGC.

207 nstrating the role of beta cell fragility in genetic predisposition to diabetes.

208 Rare familial cases reveal a genetic predisposition to disease.

209 mportance of infectious stimuli in modifying genetic predisposition to disease.Insight into the genet

210 aimed to examine the association between the genetic predisposition to dyslipdemia and type 2 diabete

211 wever, among participants with the strongest genetic predisposition to elevated IOP, greater caffeine

212 Genetic predisposition to elevated LDL-C was associated

213 Genetic predisposition to elevated triglyceride levels w

214 The authors sought to evaluate whether a genetic predisposition to elevations in plasma lipids is

215 genetic risk scores (GRSs), a measure of the genetic predisposition to elevations in plasma lipids, c

216 The aims of this study were to identify genetic predisposition to elite athletic performance by

217 A genetic predisposition to enhanced nitric oxide signalin

218 Here, we seek to understand the impact of a genetic predisposition to enhanced nitric oxide signalin

219 A genetic predisposition to enhanced nitric oxide signalin

220 light potentially novel contributors for the genetic predisposition to familial WM and indicate that

221 A genetic predisposition to fibrosis may account for much

222 Our data indicate that genetic predisposition to high blood pressure is associa

223 A genetic predisposition to high BMI as well as a genetic

224 etic predisposition to high BMI as well as a genetic predisposition to high BMI, WC, and WHRBMI combi

225 e advantages and disadvantages of disclosing genetic predisposition to high BP for risk stratificatio

226 Genetic predisposition to higher BMI did not increase th

227 obesogenic environment, to evaluate whether genetic predisposition to higher BMI has a larger magnit

228 The objective was to examine whether genetic predisposition to higher body mass index (BMI),

229 We also assessed whether genetic predisposition to higher coffee consumption was

230 Genetic predisposition to higher HDL-C levels was associ

231 Genetic predisposition to higher HDL-C, specifically to

232 ular pressure (IOP) and glaucoma and whether genetic predisposition to higher IOP modified these asso

233 A genetic predisposition to higher serum calcium levels wa

234 omising AUD treatment for individuals with a genetic predisposition to higher synaptic DA tone.

235 A genetic predisposition to higher waist-to-hip ratio adju

236 A genetic predisposition to higher waist-to-hip ratio adju

237 None of the patients were found to have a genetic predisposition to HLH.

238 d 1.05 (95% CI, 1.03-1.08; P=5.4x10(-5)) for genetic predisposition to hyperthyroidism.

239 Genetic predisposition to increased blood cholesterol an

240 Genetic predisposition to increased WHR adjusted for BMI

241 t several of these advances, with a focus on genetic predisposition to IPF and how genetic changes, w

242 Genetic predisposition to IPF is evident from its famili

243 lation in healthy volunteers account for the genetic predisposition to ischemic stroke and examined t

244 Genetic studies have provided evidence for a genetic predisposition to keloid formation, and a keloid

245 Genetic predisposition to life-threatening cardiac arrhy

246 fracture risk only in women with the lowest genetic predisposition to low BMD.

247 Given the emerging evidence for a genetic predisposition to MDB formation and NASH develop

248 des an overview of syndromes associated with genetic predisposition to MDS, discusses implications fo

249 Advances in understanding the genetic predisposition to migraine, and the discovery of

250 The genetic predisposition to multiple sclerosis (MS) is mos

251 We assessed the association between genetic predisposition to obesity and CCA IMT.

252 Genetic predisposition to obesity may have greater effec

253 habitual sleep duration could ameliorate the genetic predisposition to obesity via a favorable dietar

254 mma (PPARgamma) genotype as a measure of the genetic predisposition to obesity were investigated.

255 Independent of a genetic predisposition to obesity, maternal intake of DH

256 y, and this association may be modified by a genetic predisposition to obesity.

257 , especially among individuals having a high genetic predisposition to obesity.

258 Furthermore, a relation could depend on genetic predisposition to obesity.

259 These findings provide insights into genetic predisposition to oxidative stress and the relat

260 oding RNAs, such as microRNAs (miRNAs), to a genetic predisposition to pathological conditions has re

261 rticular, it provides further evidence for a genetic predisposition to PB and may partly explain the

262 of a series of fecal samples, we found that genetic predisposition to pB-ALL (Pax5 heterozygosity or

263 Gene association studies indicate a role for genetic predisposition to PD-ICB.

264 types outside the brain are involved in the genetic predisposition to PD.

265 m 30 studies are consistent with a view of a genetic predisposition to platinum-based chemotherapy me

266 Thus, genetic predisposition to proteome instability may be a

267 A genetic predisposition to RA, such as HLA-DR4 positivity

268 These data suggest that a genetic predisposition to raised plasma isoleucine level

269 t in II carriers, we propose a hypothesis of genetic predisposition to severe lung injury in patients

270 st, there was an inverse association between genetic predisposition to smoking and prostate cancer in

271 Genetic predisposition to smoking initiation (ever smoki

272 Genetic predisposition to smoking initiation was associa

273 Additionally, genetic predisposition to smoking was associated with st

274 A genetic predisposition to Staphylococcus aureus bacterem

275 stly with degree of pain sensitivity or with genetic predisposition to stress and/or affective distur

276 k factor for autoimmunity in children with a genetic predisposition to T1D.

277 Genetic predisposition to T2DM was associated with highe

278 Although there is evidence of genetic predisposition to the disease, most of the genet

279 We investigated genetic predisposition to the response to steroid treatm

280 This suggests an underlying constitutional genetic predisposition to these somatic changes which co

281 A genetic predisposition to thoracic aortic aneurysm has b

282 Genetic predisposition to thrombosis is still poorly und

283 According to a common hypothesis the genetic predisposition to thyroid cancer is highly heter

284 However, the extent to which genetic predisposition to tumor formation can be faithfu

285 Finally, we demonstrate that genetic predisposition to type 2 diabetes associates wit

286 xamined the interactions between a molecular genetic predisposition to various aspects of obesity and

287 e association studies (GWAS) are identifying genetic predisposition to various diseases.

288 Many patients have genetic predispositions to both forms of diabetes, resul

289 t in the investigation of Ig- and TR-related genetic predispositions to diseases.

290 Identification of genetic predispositions to IA could have important impli

291 Our findings suggest that genetic predispositions to obesity may partly exert thei

292 Genetic predispositions to venous thromboembolism (VTE)

293 A genetic predisposition toward loneliness was associated

294 ness, there is also compelling evidence of a genetic predisposition toward loneliness.

295 To address whether diet can also modulate genetic predisposition towards a given trait, we set NZM

296 he result of an infectious pathogen alone or genetic predisposition triggered by an infection.

297 achine learning accurately (96.8%) predicted genetic predisposition using 40 of 3983 amplicon sequenc

298 Genetic predisposition was assessed using heritability a

299 Furthermore, serum lipids share a genetic predisposition with both calcification in the ao

300 Results of this work suggest that genetic predisposition within astrocytes can exaggerate