ライフサイエンスコーパス: genetic profile

1 deliveries may be associated with a certain genetic profile.

2 ation was observed in those with a high-risk genetic profile.

3 hooping cough are confirmed by the resultant genetic profile.

4 cal sample with the endpoint generation of a genetic profile.

5 healthcare that accords with an individual's genetic profile.

6 togeny and oncogenesis make in molding their genetic profile.

7 prising a subpopulation are found to share a genetic profile.

8 tric oxide synthase), nitric oxide (NO), and genetic profile.

9 model prediction GWAS indicated a different genetic profile.

10 lting in foci, each of which encode a unique genetic profile.

11 nt individuals into space according to their genetic profile.

12 -GenE trial in individuals with a particular genetic profile.

13 tivity and opioid dysfunction based on their genetic profile.

14 r instance, on individual selenium status or genetic profile.

15 dalcetrapib may vary according to patients' genetic profile.

16 ammatory skin diseases, both show a distinct genetic profile.

17 cardiovascular therapy based on a patient's genetic profile.

18 characteristics, which converged with broad genetic profiles.

19 rity of renal cell carcinomas based on their genetic profiles.

20 ent phenotypes which may each have different genetic profiles.

21 s a unique Candida species by phenotypic and genetic profiles.

22 unique Candida species by its phenotypic and genetic profiles.

23 ive intent for fit patients with unfavorable genetic profiles.

24 acral melanoma (AM) arise that have distinct genetic profiles.

25 sed on transcriptional, DNA methylation, and genetic profiles.

26 ave different developmental trajectories and genetic profiles.

27 their synaptic connections, morphology, and genetic profiles.

28 o predict drug responses accurately based on genetic profiles.

29 ers and development of clinically actionable genetic profiles.

30 ed on individuals' metal exposure levels and genetic profiles.

31 to develop personalized treatments based on genetic profiles.

32 ave different developmental trajectories and genetic profiles.

33 ct neuroanatomical, cognitive, clinical, and genetic profiles.

34 gnancies that ended preterm exhibited unique genetic profiles.

35 cally as standard and high risk had distinct genetic profiles.

36 ially tailored treatment based on integrated genetic profiles.

37 al variations recently have been reported in genetic profiles.

38 quencing for pooled high-throughput chemical-genetic profiling.

39 ing as well as focused, comparative chemical-genetic profiling.

40 provides an optimal system for hormonal and genetic profiling.

41 nd/or therapeutic response be predicted from genetic profiles?

42 (EFS) (94%) compared with patients with a PR genetic profile (79%).

43 The genetic profile, activity, and neurite processing of the

44 hree-quarters of UKALL2003 patients had a GR genetic profile and a significantly improved event-free

45 While the genetic profile and clinical signs and symptoms of the d

46 ene expression determined by an individual's genetic profile and correlates 'imputed' gene expression

47 l mutations, an understanding of the somatic genetic profile and evolution of GEMM tumors is necessar

48 w a significant relationship between overall genetic profile and hand-vein constriction (P=0.29), whi

49 ed inflammatory diseases with an overlapping genetic profile and have been linked in epidemiological

50 investigated the frequency, clinical course, genetic profile and health related quality of life in Eg

51 ors could offset the effect of an adverse BP genetic profile and its effect on CVD risk.

52 study, we aimed at tracking the basal DLBCL genetic profile and its modification upon treatment usin

53 improvements in outcome can be expected from genetic profile and response-targeted therapeutics.

54 While a relationship between genetic profile and serotype was evident, no significant

55 cell line panels to reveal linkages between genetic profile and targeted-drug sensitivity.

56 melanoma; and correlation between the tumor genetic profile and the clinical behavior of the tumor.

57 esilience phenotypes, (ii) investigate their genetic profiles and (iii) assess the impact of integrat

58 bnormal placental villous tissue with unique genetic profiles and a wide spectrum of morphologic feat

59 plement conventional classification based on genetic profiles and can serve as an additional biomarke

60 nese residents, providing a large dataset of genetic profiles and electronic medical record data for

61 Its neurons have diverse genetic profiles and influence a variety of homeostatic

62 disease characterized by heterogeneous tumor genetic profiles and involving numerous pathogenic mecha

63 Genetic profiles and metastatic potential evolve alongsi

64 erized, EMZL at several sites shows distinct genetic profiles and molecular insights, bridging the pa

65 lations of cancer cells that harbor distinct genetic profiles and phenotypes that evolve over time an

66 tologic subtypes, which vary widely in their genetic profiles and tissues of origin.

67 hat the two EN individuals differed in their genetic profiles and yet were second-degree relatives.

68 Genetic profiling and barcode lineage tracing showed tha

69 pants who consent to provide DNA samples for genetic profiling and grant access to their electronic m

70 complexes in combination with comprehensive genetic profiling and protein design.

71 lysis, including gene expression monitoring, genetic profiling and the detection of pathogens.

72 lysis, including gene expression monitoring, genetic profiling and the detection of pathogens.

73 ancreatic cancer in relation to tumor stage, genetic profile, and concurrent chemotherapy.

74 roups included cardiac diagnosis, fetal sex, genetic profile, and maternal fetal environment.

75 ate-dependent function of ITCs, their unique genetic profile, and rich expression of neuromodulator r

76 ation between histopathologic heterogeneity, genetic profile, and survival.

77 including patient survival, tumor thrombus, genetic profile, and the liver-specific proteome.

78 uding disease features related to histology, genetic profile, and treatment response.

79 ieties containing 981 songs, 1296 individual genetic profiles, and 121 languages, we show that global

80 iagnosis and disease classification based on genetic profiles, and new therapeutics based on targets

81 This integrative genetic profiling approach allowed us to accurately pred

82 The genome-scale expansion of the genetic profiling approach will expedite the functional

83 ghts challenges and opportunities for future genetic profiling approaches.

84 files is essential if microarray analyses of genetic profiles are to produce reproducible data, predi

85 Because 'chemo-genetic profiles' are performed in a pooled format, infe

86 ts, 9 isolates were identified with the same genetic profiles as strains 25015 and CT39, as evidenced

87 These results argue for non-genetic profiling as a tool for the study of cancers of

88 ome) have been instrumental in identifying a genetic profile associated with sensitivity to checkpoin

89 facilitating population-based comprehensive genetic profiling at decreasing costs.

90 apillary Electrophoresis (CE) to construct a genetic profile based on polymorphic loci known as Short

91 processes, positive interactions and overall genetic profiles between pairs of genes coding for physi

92 ion to sharing analogous epidemiological and genetic profiles, biochemical characteristics, and commo

93 Combined risk scores, on the basis of genetic profile, BMI and age, resulted in excellent diab

94 apy resistance is driven not only by tumor's genetic profile but also by complex paracrine interactio

95 ted with T2D and found evidence of differing genetic profiles by age-at-onset.

96 Genetic profiling by short-tandem-repeat analysis verifi

97 Because genetic profiling can be integrated into pretreatment th

98 ences among dog breeds with respect to their genetic profile, cognitive abilities or personality trai

99 Genetic profile combined with serum urate level can be u

100 A genetic profile consisting of 174 probes was identified

101 validate the use of this technique to create genetic profile data and determine it is feasibility for

102 Genetic profiling demonstrates that SNAI2, a master EMT

103 We have previously observed that genetic profiles determined by the combination of five f

104 or all patients with WAS to their individual genetic profile, disease severity, and clinical course.

105 at the different MRSA strains evolved unique genetic profiles during infection.

106 ight mechanistic clusters of type 2 diabetes genetic profiles, each representing distinct biological

107 The genetic profile, enriched delta(15)N values, on-site pre

108 analysis, we describe the highly specialized genetic profile exhibited by terminally differentiated p

109 therapy, it supports the need for a complete genetic profile for the correct choice of therapy in all

110 ness of combining these representations with genetic profiles for DRP remains unclear.

111 ntify suspects and to maintain a database of genetic profiles for individuals who have been previousl

112 e horizon, will further refine the molecular genetic profiles for the disease, and should suggest som

113 at final diagnosis were more homogenous than genetic profiles for those who changed diagnoses.

114 is a heterogeneous disease requiring costly genetic profiling for better understanding and managemen

115 us with the capability to perform reasonable genetic profiling for lipoprotein abnormalities associat

116 shown to have derived its slightly divergent genetic profile from a bottleneck that occurred in the r

117 of attempting suicide that is similar to the genetic profile from a patient reported outcome.

118 ul tool to explore cell diversity and assess genetic profiles from developmental, functional and beha

119 pathogenesis cycle, no specific urovirulence genetic profile has been determined; this is likely due

120 e induction therapy based on an individual's genetic profile has the potential to improve treatment o

121 Jointly modeling multiple traits' genetic profiles has provided insights into the shared g

122 Molecular genetic profiling has led to the discovery of many new s

123 Conversely, recipients with a pro-apoptotic genetic profile (high Fas) or high angiotensin-1-convert

124 high anti-inflammatory and immune-regulatory genetic profile (high interleukin-10) were protected fro

125 ll be tailored to each person based on their genetic profile, high-dimensional omics-based biomarkers

126 Extended genetic profiling identifies patients deriving exception

127 these approaches has great potential because genetic profiling identifies putative disease-modifying

128 pSCC patients exhibit a similar clinical and genetic profile in comparison to other populations.

129 Better characterization of genetic profiles in age-related macular degeneration may

130 tion profiles predicted BMI independently of genetic profiles in an additive manner: 7%, 8%, and 14%

131 ion and personalized interventions targeting genetic profiles in epilepsy.

132 cal clustering analysis demonstrated similar genetic profiles in normal pancreas and early clinical s

133 ccessible and scalable strategy for chemical-genetic profiling in mammalian cells.

134 history, and then validated them with their genetic profiles, in vitro experimental efficacy, and po

135 essing domain possesses a pacemaker-specific genetic profile including Hcn4 and Tbx3.

136 A proinflammatory cytokine genetic profile increases the risk of noncardia gastric

137 ge individual dated to 980-825 cal BCE has a genetic profile indicating affinity to Beaker-related po

138 ereby disease evolves and the means by which genetic profiles influence susceptibility to and express

139 To interpret the biology of these genetic profiles, investigators must analyze this data i

140 Genetic profiling is becoming widespread in large-scale

141 Genetic profiling is done with population-optimized arra

142 Genetic profiling is one approach to risk stratification

143 High-content imaging for compound and genetic profiling is popular for drug discovery but limi

144 This genetic profile leads to nodal-like electrophysiological

145 shim and Upper Ob River regions had distinct genetic profiles, likely influenced by riverine geograph

146 This unique genetic profile makes liposarcoma an attractive candidat

147 or precision psychiatry, in which individual genetic profiles may be used to personalize risk assessm

148 Our findings hold promise that genetic profiling may help predict the vulnerability to

149 Genetic profiling may identify T-ALL patients who are li

150 ypothesized that recipient frailty score and genetic profile measured before transplant would predict

151 y outcome produced minimal effects on the DD genetic profile, moderate effects on AP and PNOS, and la

152 We show that neither genetic profile nor transcriptome reliably correlate wit

153 iation study (GWAS) leveraging a database of genetic profiles obtained through collaboration with the

154 rprints were consistent with a change in the genetic profile of C. parvum isolates following transmis

155 ncreases Plcl2 expression, which manifests a genetic profile of compromised oxytocin signaling.

156 test the hypothesis that the hemodynamic and genetic profile of Cpc-PH would more closely resemble PA

157 of the present study was to investigate the genetic profile of DD development using phenotypic and g

158 The genetic profile of five cytokines was studied in 68 LTx

159 ina next generation sequencing to generate a genetic profile of human polymorphisms associated with m

160 rammes will facilitate the monitoring of the genetic profile of individuals of interest, the tracking

161 ate clinical stage primary INS resembled the genetic profile of INS-metastatic lymph nodes.

162 The genetic profile of LGR5(+ve) cells includes both markers

163 In mice lacking Hb9, the genetic profile of MNs is significantly altered, particu

164 The genetic profile of modern North African populations is t

165 (SSRs) markers analysis, we characterise the genetic profile of monovarietal olive oils.

166 ent body sizes, we discover that the overall genetic profile of size evolution in nature and in the l

167 The genetic profile of small-medium CMNs was significantly d

168 es, researches are looking into altering the genetic profile of the beta cell as a way to manage meta

169 The typical genetic profile of the cluster associated with low RV-A1

170 We have been able to characterize the genetic profile of the first Pompeian' genome, which has

171 rom high-throughput sequencing and outputs a genetic profile of the IGHV locus with the read coverage

172 We aimed to evaluate the genetic profile of TLR pathway-related key genes; the my

173 ate that B and T cells function to shape the genetic profile of tumors in various tumor types, despit

174 study, we examined the susceptibilities and genetic profiles of 20 nonduplicate isolates of A. bauma

175 dence for such a correlation by studying the genetic profiles of 22 strains of B. burgdorferi sensu l

176 ity, preclinical approaches, epigenetic, and genetic profiles of A-HCC, and discuss the current insig

177 of the risk profiles, biomarker profiles and genetic profiles of adults with DS with those of individ

178 ens by investigating the drug resistance and genetic profiles of commonly isolated GNB causing neonat

179 However, systematic identification of genetic profiles of disease risk is limited by the avail

180 Genetic profiles of diverse accessions indicated limited

181 is a growing field that endeavors to obtain genetic profiles of individual cells.

182 cer; however, it has been challenging to use genetic profiles of individual patients in identifying t

183 his innovative approach considers the unique genetic profiles of individuals, along with a range of v

184 The genetic profiles of PTFL and t(14;18)(-) FL in adults in

185 The genetic profiles of recurrent and metastatic tumors were

186 presence of tumor pathology and with defined genetic profiles of the Rb gene, from these sites.

187 Comparisons of the genetic profiles of West Eurasians before and after admi

188 Here, we perform integrated genetic profiling of 1140 primary UMs, including 131 sma

189 Our genetic profiling of 293 BCCs found the highest mutation

190 Genetic profiling of CgA-expressing 6T3 versus CgA- and

191 Genetic profiling of hair follicle stem cells revealed s

192 erial analysis of gene expression (SAGE) for genetic profiling of highly purified human blood platele

193 F-treated keratinocytes and compared it with genetic profiling of HS lesions.

194 -edited HSCs at clonal density, allowing for genetic profiling of individual clones before transplant

195 CRISPR screens combined with molecular and genetic profiling of large panels of cell lines are help

196 Genetic profiling of malaria infections can guide this d

197 Genetic profiling of MRD vs diagnostic PCs was performed

198 d insulin receptor inhibitors, together with genetic profiling of responders, might pave the way towa

199 We report on the genetic profiling of single cancer cells, exploiting a c

200 Genetic profiling of these field cells indicated that th

201 Finally, genetic profiling of transposon-induced mutations identi

202 s approach provides a novel strategy for the genetic profiling of tumour cells via integrated "amplif

203 The large-scale genetic profiling of tumours can identify potentially ac

204 een extensively studied on the level of cell genetic profiles or cellular composition, tumor morpholo

205 fetal sex (P for interaction = .04), but not genetic profile (P for interaction = .16) or maternal-fe

206 The comparative analysis of the genetic profile performed in healthy and sporadic ALS hN

207 Using a combination of genetic profiling, physiology and behavioural analyses,

208 Future studies need to assess whether such genetic profiles predict adverse outcomes in U.S. popula

209 ic effects on periodontitis; reinforcing the genetic profile predisposing to periodontitis.

210 ndings highlight the potential importance of genetic profiling pretreatment to identify those most su

211 Single-cell genetic profiling provides a potential resolution to thi

212 n the cell lines are likely to reflect their genetic profile rather than the embryonic stage from whi

213 t assumption, investigating whether forensic genetic profiles reveal information about gene-expressio

214 Examination of the pulmonary genetic profiles revealed differentially expressed genes

215 Genetic profiling revealed that molecular subgroups of p

216 gated whether the association of a validated genetic profile risk score for obesity (GPRS-obesity) wi

217 test for pleiotropy between MDD and EA: (i) genetic profile risk scores (GPRS) derived from training

218 0.08% (P=0.020) of the variance in BMI and a genetic profile score using BMI-specific variants accoun

219 A genetic profile score using cognition-specific genetic v

220 The interaction of genetic profile scores and early life stress predicted l

221 The present study tested the hypothesis that genetic profile scores combining variance across 10 sing

222 We found that stress-system genetic profile scores positively predicted cortisol lev

223 s, the Klotho protein level and not only the genetic profile should be considered.

224 Genetic profiling should be integrated into classical me

225 An unfavorable versus favorable nine-variant genetic profile showed increased risk odds ratios of 1.3

226 Finally, genetic profiling showed that there was no evidence of A

227 ulture derived most of their ancestry from a genetic profile similar to that of Sicily and the Aegean

228 n our endogenous u-opioid system and how our genetic profile (specifically catechol-O-methyltransfera

229 Genetic profiling studies have been conducted to differe

230 ual disease, lymphoblast genetics (including genetic profiling studies), and host-related pharmacogen

231 n Multiple Myeloma to Personal Assessment of Genetic Profile study ( NCT01454297 ) is a longitudinal,

232 The genetic profiles suggested that a single leukemic progen

233 within the past 540 years, diverge in their genetic profiles, suggesting differences in their intera

234 How MIA interacts with a genetic profile susceptible to SZ is challenging to test

235 In addition, application of genetic profiling techniques to a variety of tumor types

236 nd interaction, presenting a notably diverse genetic profile that includes North African and Eastern

237 abnormality in the MMP3 gene is part of the genetic profile that predisposes to aneurysmal disease.

238 remaining tumors (n = 18) showed a balanced genetic profile that was significantly associated with a

239 ally tailored treatments based on integrated genetic profiles that are able to predict the benefit of

240 ith development and also identified unifying genetic profiles that are shared between mature glia.

241 er research is the construction of molecular genetic profiles that characterize each type of human ne

242 The molecular genetic profiles that characterize pancreatic ductal neo

243 to pharmacogenetic research, by constructing genetic profiles that could be used to individualize the

244 the latter into three clusters with distinct genetic profiles that could reflect their molecular unde

245 ever, the underlying mechanisms and detailed genetic profiles that set these tumors apart are still e

246 Despite studies that have investigated his genetic profile, the relation of the Iceman s maternal l

247 The genetic profile therefore appears to be an important det

248 These mice, engineered with a common genetic profile to human melanoma, provide a system to s

249 ultimately enabling a correlation of patient genetic profiles to clinically effective kinase inhibito

250 extendable approach that can provide timely genetic profiles to inform clinical and surveillance act

251 asket trials that combine histopathology and genetic profiling to individualize treatment approaches

252 ubgroups of homogeneous individuals based on genetic profiles together with heuristic clinical analys

253 ress in genome-wide studies of ICC including genetic profiling, transcriptomics, and epigenomics.

254 gs provide converging evidence that distinct genetic profiles underlie specific mental processes of h

255 In this study, the broad molecular genetics profile underlying the novel EOM phenotype was

256 of glial tumorigenesis and maintained their genetic profiles upon recurrence.

257 ular overgrowth syndromes, we employed tumor genetic profiling via high-depth next-generation sequenc

258 A genetic profiling was also carried out using microsatell

259 Genetic profiling was done by enterobacterial repetitive

260 The prevalence of clinical symptoms and genetic profile were obtained, and then the phenotypic c

261 The PCR-ME genetic profiles were analyzed using binning palettes ge

262 working memory capacity and dopamine-related genetic profiles were associated with performance in two

263 Different Rb genetic profiles were found in liver tissue near each tu

264 genes exhibiting positive GIs and/or similar genetic profiles were predictive of the corresponding pr

265 Overall, based on this cohort, genetic profiles were similar except for a significantly

266 A favorable genetic profile, when combined with an optimal training

267 t an algorithm for spatiotemporal mapping of genetic profiles, which allow for direct estimates of pa

268 high-risk persons must be identified in whom genetic profiling will also be cost-effective.

269 nd dosage and predict outcome by correlating genetic profile with disease presentation.

270 hese cancers are mirrored in their molecular genetic profile with type I showing defects in DNA-misma

271 duals with non-European ancestry that merges genetic profiles with EMR data and enables longitudinal

272 AP and PNOS had similar genetic profiles with levels of SZ FGRS similar to DD bu

273 enge because of the interactions of specific genetic profiles with numerous environmental factors tha

274 e approach that combined transcriptional and genetic profiling with digital spatial profiling.