ライフサイエンスコーパス: genetic recombination

1 g the 'Role for the c-Abl tyrosine kinase in genetic recombination'.

2 hanisms such as horizontal gene transfer and genetic recombination.

3 ich we particularly discuss the variation of genetic recombination.

4 embedded within a 3,113-kb region that lacks genetic recombination.

5 imPol promotes sister chromatid exchange and genetic recombination.

6 l DNA and is also involved in DNA repair and genetic recombination.

7 y movements that ultimately serve to promote genetic recombination.

8 etic variation or by subsequent mutation and genetic recombination.

9 strand exchange, the two essential steps of genetic recombination.

10 ble-strand breaks (DSBs) and is required for genetic recombination.

11 Holliday junctions are intermediates in genetic recombination.

12 t Y chromosomes degenerate because they lack genetic recombination.

13 ear to be due to complementation rather than genetic recombination.

14 in displacing RPA in the initiation stage of genetic recombination.

15 s architecture has potential implications in genetic recombination.

16 nt model system for understanding homologous genetic recombination.

17 g in DNA transposition-a specialized form of genetic recombination.

18 e Holliday junction is a key intermediate in genetic recombination.

19 Thus, long CTG.CAG tracts are hot spots for genetic recombination.

20 r gene that is activated by Cre/lox-mediated genetic recombination.

21 aged DNA or stalled replication can initiate genetic recombination.

22 lly were investigated for their relevance to genetic recombination.

23 family of recombinases active in homologous genetic recombination.

24 ion of the genes required for DNA uptake and genetic recombination.

25 damage, and serve to ensure the fidelity of genetic recombination.

26 e four-way DNA junction that is important in genetic recombination.

27 is a key DNA intermediate in the process of genetic recombination.

28 lliday junction is a central intermediate in genetic recombination.

29 ecBCD enzyme, it is completely defective for genetic recombination.

30 ility, particularly to prevent 'promiscuous' genetic recombination.

31 o play different roles during DNA repair and genetic recombination.

32 ne family of strand transferases involved in genetic recombination.

33 DMC1 family of strand transferases acting in genetic recombination.

34 he removal of nonhomologous DNA tails during genetic recombination.

35 ost intensively studied enzyme in homologous genetic recombination.

36 ast one PspA has been acquired via localized genetic recombination.

37 le functions in DNA replication, repair, and genetic recombination.

38 to remove 3' nonhomologous DNA tails during genetic recombination.

39 lain the alignment of homologous DNAs during genetic recombination.

40 DNA synthesis and is involved in retroviral genetic recombination.

41 of a DNA Holliday junction is a key step in genetic recombination.

42 acteriophage lambda suit it for the study of genetic recombination.

43 th MSH2 and functions in mismatch repair and genetic recombination.

44 is a central intermediate in the process of genetic recombination.

45 ctions in DNA double-strand break repair and genetic recombination.

46 branch migration is a fundamental process in genetic recombination.

47 ion that can occur for variants generated by genetic recombination.

48 change reactions suggestive of a key role in genetic recombination.

49 n resolves DNA intermediates produced during genetic recombination.

50 segregation at MII may also be influenced by genetic recombination.

51 ration of Holliday junction intermediates in genetic recombination.

52 p between the processes of SOS induction and genetic recombination.

53 erevisiae RAD52 gene plays a pivotal role in genetic recombination.

54 n of cell cycle checkpoints, DNA repair, and genetic recombination.

55 somes or extensive genomic regions that lack genetic recombination.

56 old structural genetic variants that modify genetic recombination.

57 ed that ST-452 could have originated through genetic recombination.

58 revealing new details about the mechanics of genetic recombination.

59 virus replication and, in some cases, viral genetic recombination.

60 sviruses by regulating viral replication and genetic recombination.

61 in DNA repair and other processes involving genetic recombination.

62 s integrated in tumor DNA carried markers of genetic recombination.

63 e males, or otherwise exhibit some degree of genetic recombination.

64 the genome but account for nearly all of the genetic recombination.

65 rand exchange reaction as part of homologous genetic recombination.

66 region of chromosome 7AL that has suppressed genetic recombination.

67 e of a pathogenicity island acquired through genetic recombination.

68 ism of antigenic variation is not homologous genetic recombination.

69 To study genetic recombination, 16 progeny clones were genotyped

70 Regulation of genetic recombination, a proposed role for RecQ helicase

71 shift in IYSVBR genotype is attributable to genetic recombination, abundance of purifying selection,

72 DNA strand exchange plays a central role in genetic recombination across all kingdoms of life, but t

73 izobium species we observed coexist with low genetic recombination across their core genomes.

74 somal rearrangements, which we attributed to genetic recombination, activity of mobile elements, and

75 ements are important for processes including genetic recombination, adaptation, and speciation.

76 Genetic recombination affects levels of variability and

77 iple functions, suggesting that variation of genetic recombination along a chromosomal arm is the res

78 ysis of individual segment datasets suggests genetic recombination also occurs.

79 e bacterium and that these pathogens utilize genetic recombination and a large, noncore set of genes

80 same kind of combinatorial diversity as does genetic recombination and antibody formation.

81 ages of meiotic prophase I, both at sites of genetic recombination and at gene promoters.

82 cted to distal chromosomal regions, limiting genetic recombination and breeding flexibility.

83 The major pathway of genetic recombination and DNA break repair in Escherichi

84 RAD51, RAD55, and RAD57 genes, required for genetic recombination and DNA double-strand-break repair

85 day intermediates and correct the defects in genetic recombination and DNA repair associated with ina

86 cells, RAD52 protein plays a central role in genetic recombination and DNA repair by (i) promoting th

87 of RecB and tested the resulting mutants for genetic recombination and DNA repair in vivo.

88 NA strand-exchange reaction utilized in both genetic recombination and DNA repair.

89 tion of Holliday junctions that arise during genetic recombination and DNA repair.

90 i process recombination intermediates during genetic recombination and DNA repair.

91 ichia coli process Holliday junctions during genetic recombination and DNA repair.

92 ranch migration of Holliday intermediates in genetic recombination and DNA repair.

93 ranch migration of Holliday junctions during genetic recombination and DNA repair.

94 ic data has implicated BLM in the process of genetic recombination and DNA repair.

95 Genetic recombination and double-strand break repair adv

96 double-stranded DNA and is involved in both genetic recombination and double-strand break repair in

97 The RAD54 and RAD51 genes are involved in genetic recombination and double-strand break repair in

98 pendent recombinases plays a crucial role in genetic recombination and double-stranded DNA break repa

99 Chromosome inversions suppress genetic recombination and establish co-adapted gene comp

100 Amazingly, host factors affecting viral genetic recombination and evolution have also been ident

101 AD51 gene function is required for efficient genetic recombination and for DNA double-strand break re

102 nd breaks that occur during DNA replication, genetic recombination and gene rearrangements.

103 lity to integrate into tissues could explain genetic recombination and generation of novel pathogens.

104 Escherichia coli is required for homologous genetic recombination and induction of the SOS regulon.

105 selection coefficients, and the addition of genetic recombination and local linkage brings about sig

106 ection, which enables us to explicitly model genetic recombination and local linkage.

107 ter centroblasts, which undergo simultaneous genetic recombination and massive clonal expansion.

108 und to be deficient in repair of DNA damage, genetic recombination and meiosis.

109 n of spermatogonia, spermatocytes undergoing genetic recombination and meiotic divisions, and differe

110 insights will empower efforts to manipulate genetic recombination and modify epigenetic landscapes a

111 mosome arms, regions characterized by higher genetic recombination and more repeat sequences than aut

112 ifically, DNA shuffling and other methods of genetic recombination and mutation have resulted in the

113 to changing environmental conditions through genetic recombination and natural selection alone.

114 ral intermediate state of DNA for homologous genetic recombination and other genetic processes such a

115 During general genetic recombination and recombinational DNA repair, DN

116 omyces cerevisiae RAD51 gene is required for genetic recombination and recombinational repair of DNA

117 cerevisiae RAD51 gene product takes part in genetic recombination and repair of DNA double strand br

118 es cerevisiae Rad51 protein is important for genetic recombination and repair of DNA double-strand br

119 gy in duplex DNA is central to understanding genetic recombination and repair of double-strand breaks

120 is formed as a transient intermediate during genetic recombination and repair processes in the cell.

121 ired in mammalian cells for normal levels of genetic recombination and resistance to DNA-damaging age

122 H1 and HMG-1 in biological processes such as genetic recombination and retroviral integration.

123 ntial to the two distinct cellular events of genetic recombination and SOS induction in Escherichia c

124 During genetic recombination and the recombinational repair of

125 rtant roles in the late stages of homologous genetic recombination and the recombinational repair of

126 mplex protein machines, initiates homologous genetic recombination and the repair of broken DNA.

127 rs of the RAD52 epistasis group required for genetic recombination and the repair of DNA double-stran

128 s RAD51 or RAD52 result in severe defects in genetic recombination and the repair of double-strand DN

129 Genetic recombination and, in particular, genetic shuffl

130 B cells that have class switched to IgD via genetic recombination (and thus become class switched to

131 to chromosomal instability, abnormalities in genetic recombination, and defective signaling to progra

132 g the mechanisms underlying DNA replication, genetic recombination, and the landscape of mammalian ge

133 s of Msh2, Msh3, Rad1, and Rad10 proteins in genetic recombination are discussed.

134 sults indicate that mismatches formed during genetic recombination are processed differently than dur

135 The presumed advantages of genetic recombinations are difficult to demonstrate dire

136 Y (or W) chromosomes lack genetic recombination, are male- (female-) limited, and

137 Genetic recombination arises during meiosis through the

138 Using a promoter trap that relies on genetic recombination as a reporter of gene expression,

139 tate, which excludes the biological need for genetic recombination, as well as limits tools to study

140 Genetic recombination associated with sexual reproductio

141 tes that have deleted fetA sequences through genetic recombination at repetitive elements.

142 on the silencing of Pol II transcription and genetic recombination at the ribosomal DNA locus (rDNA)

143 es that confer an advantage to sexuality and genetic recombination, at either the population or indiv

144 tion should consider the possibility of rare genetic recombination, because such events seem to be ne

145 Interstrain genetic recombination between distant loci in the VP1 an

146 like its bacterial homologue RecA, catalyzes genetic recombination between homologous single and doub

147 lts provide direct experimental evidence for genetic recombination between two different retroviral s

148 that induced viral co-infection facilitated genetic recombination between two different viruses, the

149 stacles such as high sequence similarity and genetic recombinations between CYP2D6 and evolutionarily

150 he co-existence of precursor cells harboring genetic recombinations between the immunoglobulin heavy-

151 tified mutations in MSH2 that do not disrupt genetic recombination but confer a strong defect in mism

152 negatively correlate with the rates of local genetic recombination, but no significant correlation be

153 n of bacteriophage lambda acts in homologous genetic recombination by catalyzing the annealing of com

154 sion repair proteins have been implicated in genetic recombination by experiments in Saccharomyces ce

155 the only hyperthermophilic archaeon in which genetic recombination can be assayed by conjugation and

156 In host-associated microbes, genetic recombination can be disrupted by confinement to

157 Genetic recombination can be important evolutionarily in

158 Genetic recombination can lead to the formation of inter

159 d poliovirus RNAs, we have demonstrated that genetic recombination can occur in a cell-free system th

160 Genetic recombination catalyzed by lambda's Red pathway

161 zing radiation-associated phenomena, namely, genetic recombination, chromosomal translocation, cell i

162 ecause topoisomerase I is thought to promote genetic recombination, competence to enhance topoisomera

163 Genetic recombination contributes to human immunodeficie

164 These results emphasize that genetic recombination could contribute to high-level mul

165 lusion, in all 6 cases studied, there was no genetic recombination detected among HCV quasispecies or

166 Holliday junctions play a central role in genetic recombination, DNA repair and other cellular pro

167 id exchange reaction is a common feature for genetic recombination, DNA replication and transcription

168 smatch repair system is the major barrier to genetic recombination during interspecific sexual conjug

169 termed hot spots, are predisposed to undergo genetic recombination during meiosis at higher levels re

170 In mammals, genetic recombination during meiosis is limited to a set

171 Reduction in chromosome number and genetic recombination during meiosis require the prior a

172 A case in point is the control of genetic recombination during meiosis, which leads to cro

173 variation generated by frequent mutation and genetic recombination during reverse transcription.

174 n ancient mechanism that evolved to restrict genetic recombination during sexual development.

175 rial samples of genomes while accounting for genetic recombination effect and local linkage informati

176 ration of the biochemical mechanisms driving genetic recombination, elucidating the molecular intrica

177 lly acquire new M protein gene types through genetic recombination (emm switching).

178 Genetic recombination ensures proper chromosome segregat

179 genome triplication event, and the rates of genetic recombination estimated/deduced by the compariso

180 In bacteriophage T4, homologous genetic recombination events are catalyzed by a presynap

181 Genetic recombination events in the pathogen can generat

182 olliday-type junctions formed during in vivo genetic recombination events.

183 bufavirus 1 might have arisen from multiple genetic recombination events.

184 increased heterozygosity is preserved after genetic recombination following periods of sexual reprod

185 CTG.CAG sequences, multiple fold expansions, genetic recombination, formation of new recombinant DNA

186 Genetic recombination generates novel trait combinations

187 new recombination map for future studies of genetic recombination, genome stability and evolution.

188 of LTR-RTs in relation to the rates of local genetic recombination (GR) and gene densities in the ric

189 spective, and while it retains similarities, genetic recombination guarantees diversity so that we do

190 Genetic recombination has been considered a driving forc

191 While reduced genetic recombination has been demonstrated in maternal

192 Altered genetic recombination has been identified as the first m

193 f the Holliday junction (HJ) intermediate in genetic recombination has been prepared and analyzed in-

194 Genetic recombination has frequently been observed in co

195 he Drosophila genome that have low levels of genetic recombination helps us understand the prevalence

196 Viral genetic recombination helps viruses in an evolutionary a

197 RDM9/ZCWPW1) system in vertebrates remodeled genetic recombination hotspot selection from an ancestra

198 Srs2 is known to suppress inappropriate genetic recombination; however, the TNR expansion phenot

199 Genetic recombination impacts on neisserial biology in t

200 Genetic recombination in all kingdoms of life initiates

201 Genetic recombination in bacteria is facilitated by the

202 Most, but not all, homologous genetic recombination in bacteria is mediated by the Rec

203 stability can lead to increased frequency of genetic recombination in bacterial genomes.

204 ed within or close to AU-rich regions during genetic recombination in brome mosaic bromovirus (BMV).

205 system, MerCreMer (MCM), was used to induce genetic recombination in cardiac myocytes, which led to

206 c DNA double-stranded breaks (DSBs) initiate genetic recombination in discrete areas of the genome ca

207 Genetic recombination in Escherichia coli is stimulated

208 inally proposed by Robin Holliday to explain genetic recombination in fungi, now appears to be a pivo

209 contrast to the higher-than-average rate of genetic recombination in gene-rich telomeric region on H

210 fer during reverse transcription can produce genetic recombination in human immunodeficiency virus ty

211 it possible to investigate the mechanisms of genetic recombination in mammals in greater detail than

212 es in proximity over a long range, promoting genetic recombination in numerous hot spots.

213 Genetic recombination in RNA viruses is a major force be

214 Genetic recombination in single-strand, positive-sense R

215 gs are consistent with a role for suppressed genetic recombination in speciation of A. gambiae.

216 particular to discovering and characterizing genetic recombination in T4, to redefining the nature of

217 lato species was consistent with a role for genetic recombination in the generation of dbpA diversit

218 Furthermore, KC-derived Cre led to genetic recombination in the LCs.

219 A prerequisite to genetic recombination in the T4 bacteriophage is the for

220 nase, it promotes repair of dsDNA breaks and genetic recombination in the vicinity of chi recombinati

221 ther lesions in DNA can stimulate homologous genetic recombination in two quite different ways: by pr

222 hetic errors generated during replication or genetic recombination in virtually all organisms.

223 tituted for isoleucine-225, is defective for genetic recombination in vivo and for DNA strand exchang

224 opoisomerases may either promote or suppress genetic recombination in vivo.

225 insights into how a gain of function through genetic recombination, in particular cross-order recombi

226 Genetic recombination increases diversity in HIV-1 popul

227 first evidence of error-prone DNA repair and genetic recombination induced by DNA damage in an archae

228 ous DNA molecules, we have reconstituted the genetic recombination-initiated pathway that initiates D

229 n (4H) DNA, an in vitro mimic of the in vivo genetic recombination intermediate known as the Holliday

230 Genetic recombination involves either the homo-logous ex

231 Genetic recombination involves the exchange of genetic m

232 The process of genetic recombination involves the formation of branched

233 We hypothesize that this high frequency of genetic recombination is a common feature of primate len

234 Genetic recombination is a critical cellular process tha

235 nary significance of sexual reproduction and genetic recombination is a long-standing puzzle.

236 Genetic recombination is a major force driving the evolu

237 In bacteria, genetic recombination is a major mechanism for DNA repai

238 Genetic recombination is a robust mechanism for expandin

239 Drosophila and humans indicate that aberrant genetic recombination is an important component of nondi

240 Genetic recombination is believed to assist HIV-1 divers

241 Genetic recombination is generally evenly distributed al

242 Genetic recombination is largely confined to about one-t

243 In many organisms, the rate of genetic recombination is not uniform along the length of

244 y syndrome coronavirus (MERS-CoV).IMPORTANCE Genetic recombination is often demonstrated in coronavir

245 bacteria, the primary function of homologous genetic recombination is the repair of stalled or collap

246 Genetic recombination is usually considered to facilitat

247 icipates in DNA replication, DNA repair, and genetic recombination; it is the most extensively studie

248 Thus, an understanding of the genetic recombination landscape across the maize (Zea ma

249 o maintain genome stability and in modifying genetic recombination landscapes.

250 hort-term evolutionary advantages, a lack of genetic recombination leads to the accumulation over tim

251 c ortholog pairs, the possibility of unequal genetic recombination makes the assignments inconclusive

252 We report a genetic recombination map for Sorghum of 2512 loci space

253 Genetic recombination may play a role in B. burgdorferi

254 d gelonin, via both chemical conjugation and genetic recombination methods, with low molecular weight

255 st partially explain the higher frequency of genetic recombination observed for human immunodeficienc

256 the interaction between mismatch repair and genetic recombination observed in genetic studies.

257 This cloning by genetic recombination obviates the need for ligations or

258 Genetic recombination occurs between homologous DNA mole

259 Genetic recombination occurs during meiosis, the key dev

260 Genetic recombination occurs in all organisms and is vit

261 Genetic recombination of plus-strand RNA viruses is an i

262 ir large repeat-rich genomes and the lack of genetic recombination or cultivar (cv)-specific sequence

263 gical role, e.g., in nucleosome positioning, genetic recombination, or chromosome superfolding.

264 s between these two species with significant genetic recombination over the last 200 years.

265 structure that occurs as an intermediate in genetic recombination pathways, including site-specific

266 nome and to synthesize DNA in DNA repair and genetic recombination pathways.

267 aquaporin 5 (AQP5) Cre mouse line to produce genetic recombination predominantly within the acinar ce

268 ral decades, research into the mechanisms of genetic recombination proceeded without a complete under

269 Genetic recombination provides an important mechanism fo

270 The variation of genetic recombination rate along a chromosomal arm is sh

271 cated that the protein is mainly involved in genetic recombination rather than DNA repair.

272 To better understand the genetic recombination related with the acquisition of dr

273 critically important molecular mechanism is genetic recombination, required for the beneficial reass

274 r that the population is undergoing frequent genetic recombination, resulting in a mosaic genome pool

275 ovided specific dose-dependent loxP-mediated genetic recombination, resulting in reporter gene expres

276 asing understanding of the interplay between genetic recombination, selection and mutation and their

277 s to explain the evolutionary maintenance of genetic recombination states that the reshuffling of gen

278 The strain was constructed by serial genetic recombination steps, but the underlying sequence

279 do this, we used an inducible Cre-dependent genetic recombination strategy to delete ENaC function a

280 itrate reductase (SNaR) that was produced by genetic recombination techniques.

281 four-stranded DNA structure is a key step in genetic recombination that affects the extent of genetic

282 RuvB is a bacterial protein involved in genetic recombination that bears structural similarity t

283 iday junction is a prominent intermediate in genetic recombination that consists of four double helic

284 ss switch in B lymphocytes involves a unique genetic recombination that fuses specific regions within

285 se that these boundary sequences are foci of genetic recombination that serve to assort the modules a

286 reproduction focuses on the benefits of the genetic recombination that takes place during meiosis.

287 Through genetic recombination, the adaptive immune system genera

288 Through genetic recombination, there is fundamentally no limit t

289 ife; the reactions involved can also promote genetic recombination to aid evolution.

290 RecA is a key protein linking genetic recombination to DNA replication and repair in b

291 s varied independently of each other, but no genetic recombination was detected in a study of 40 huma

292 apospory-specific genomic region in which no genetic recombination was detected.

293 nce DNA TE insertions and the rates of local genetic recombination was detected.

294 gh the presence of males is expected because genetic recombination was observed in a few sexually rep

295 dreich's ataxia, respectively) can expand by genetic recombination, we investigated the capacity of t

296 teractions, including viral interference and genetic recombination, which cannot be studied in infect

297 Genetic recombination, which provides a physical connect

298 etic analysis did not reveal any evidence of genetic recombination with either HTLV-1, HTLV-2, or STL

299 xtensive DNA replication can be triggered by genetic recombination, with assembly of a replication co

300 day) junction is the central intermediate of genetic recombination, yet key aspects of its conformati