ライフサイエンスコーパス: genetic risk factor

1 variant, which is the highest schizophrenia genetic risk factor.

2 heir use is human (h)-APOE4, the greatest AD genetic risk factor.

3 une-mediated responses and environmental and genetic risk factors.

4 d have led to the identification of numerous genetic risk factors.

5 in humans are amyotrophic lateral sclerosis genetic risk factors.

6 (OCD) are often comorbid and likely to share genetic risk factors.

7 sociated clinical features and outcomes, and genetic risk factors.

8 complex disease with both environmental and genetic risk factors.

9 ome is then determined by R1210C-independent genetic risk factors.

10 sk factors such as age, gender, smoking, and genetic risk factors.

11 se-control group of 213 patients to identify genetic risk factors.

12 nnot be attributed to major known IBD and RA genetic risk factors.

13 nders, a portion arises from common familial/genetic risk factors.

14 opmental disorders that are thought to share genetic risk factors.

15 g findings as well as strategies for mapping genetic risk factors.

16 y lipoproteins, independent of age, sex, and genetic risk factors.

17 e predisposition of certain breeds indicates genetic risk factors.

18 hat schizophrenia and bipolar disorder share genetic risk factors.

19 l cardiomyocyte replication to determine the genetic risk factors.

20 Myopia is caused by both environmental and genetic risk factors.

21 regions to determine the local influence of genetic risk factors.

22 this phenomenon might be explained by shared genetic risk factors.

23 ating the pathophysiology of high-penetrance genetic risk factors.

24 The effect of known genetic risk factors (97 single-nucleotide polymorphisms

25 This review explores a newly described major genetic risk factor, a mutation in the skin matrix prote

26 As disrupted-in-schizophrenia 1 (DISC1) is a genetic risk factor across a spectrum of psychiatric dis

27 ia by illuminating how different established genetic risk factors act and interact to influence liabi

28 prominent in males than in females, with new genetic risk factors affecting irritability in early and

29 pathology to understand how the G2019S LRRK2 genetic risk factor affects the spread and toxicity of a

30 e independent associations of modifiable and genetic risk factors allow more precise identification o

31 y complex and heterogeneous with most of the genetic risk factors also found in the unaffected genera

32 ry arthritis for which HLA-B*27 is the major genetic risk factor, although its role in the aetiology

33 performance, and thus, the combination of a genetic risk factor and altered modulation may provide i

34 This module was enriched in AD genetic risk factors and in microglia and astrocyte prot

35 Although genetic risk factors and network-level neuroimaging abno

36 to increase, with the aim of discovering new genetic risk factors and obtaining insight into the dise

37 ve disorders is imperative to discover novel genetic risk factors and potential therapeutic entry poi

38 enabling the functional validation of known genetic risk factors and potentially pathogenic alleles

39 iations between demographic, behavioral, and genetic risk factors and the 2 outcomes were analyzed us

40 The genetic risk factors and underlying pathology of ARHI ar

41 Discovering new genetic risk factors and understanding the mechanisms wh

42 gender dependent and highly sensitive to the genetic risk factor APOE4 Our findings highlight the spe

43 uals who are negative for the established AD genetic risk factor, apolipoprotein E (APOE) varepsilon4

44 Environmental and genetic risk factors are implicated in the pathogenesis

45 and provide insight into how genetic and non-genetic risk factors are mechanistically linked to clini

46 However, the contributing genetic risk factors are poorly understood.

47 ube defects occur frequently, yet underlying genetic risk factors are poorly understood.

48 The extent to which genetic risk factors are shared between childhood-onset

49 Many genetic risk factors are shared between SpA and IBD, and

50 Most of the genetic risk factors are unknown.

51 APOE4 is the strongest genetic risk factor associated with late-onset Alzheimer

52 tein J (ApoJ), is the third most predominant genetic risk factor associated with late-onset Alzheimer

53 patients and healthy controls have unearthed genetic risk factors associated with a range of neurolog

54 s review summarizes the current knowledge on genetic risk factors associated with LOAD risk in Caribb

55 AD; in which it is the single most important genetic risk factor), atherosclerotic cardiovascular dis

56 ) disorders, suggesting a significant common genetic risk factors between insomnia and substance use.

57 In this study, we sought to identify the PA genetic risk factors by focusing on causative mutations

58 This study suggests that the AD genetic risk factor CALM modulates autophagy, and this m

59 tric disorders overlap in symptoms and share genetic risk factors, challenging their current classifi

60 To understand how genetic risk factors contribute to SCC, studies of ESPC

61 Our findings suggest shared genetic risk factors contribute to the epidemiological a

62 ral network analysis both indicated that the genetic risk factors contributed positively to the predi

63 These findings help elucidate how diverse genetic risk factors converge onto specific molecular pr

64 cells during development, superimposed upon genetic risk factors, could contribute to defective diff

65 evidence for infectious, environmental, and genetic risk factors described.

66 DD can successfully lead to the discovery of genetic risk factor despite reduced sample size.

67 ajor bottleneck in the identification of its genetic risk factors, especially in genome-wide associat

68 s such as type 2 diabetes suggests different genetic risk factors exist for glycosuria during pregnan

69 Our findings suggest that psychiatric genetic risk factors expressed in astrocytes could affec

70 Disrupted-in-Schizophrenia-1 (DISC1) is a genetic risk factor for a wide range of major mental dis

71 E (APOE) epsilon4 allele is the most common genetic risk factor for AD and is related to a pro-infla

72 The most prevalent genetic risk factor for AD is the epsilon4 allele of apo

73 The most significant genetic risk factor for AD is the epsilon4 allele of apo

74 Coupled with a significant genetic risk factor for AD, changes in modulation may pr

75 The APOE4 allele is not only the strongest genetic risk factor for AD, it also affects risk for car

76 addition, we found that APOE, the strongest genetic risk factor for AD, regulates neurodegeneration

77 viously demonstrated that the most prevalent genetic risk factor for AD, the ApoE4 allele, is correla

78 tations, and apolipoprotein E, the strongest genetic risk factor for AD.

79 r dysfunction constitute the most well-known genetic risk factor for AD.

80 occurring genotype of APOE, is the greatest genetic risk factor for AD; increasing risk up to 12-fol

81 Our results implicate BDNF as a genetic risk factor for ADHD, potentially by virtue of i

82 encoding apolipoprotein E (apoE) is a strong genetic risk factor for aging-related cognitive decline

83 at rare variants in MYH15 represent a likely genetic risk factor for ALS.

84 he immune response of microglia, is a strong genetic risk factor for Alzheimer disease (AD) and possi

85 APOE varepsilon4, the most significant genetic risk factor for Alzheimer disease (AD), may mask

86 ous system (CNS) and as the most influential genetic risk factor for Alzheimer disease (AD).

87 oprotein E (APOE) epsilon4 allele is a major genetic risk factor for Alzheimer disease and dementia.

88 he apolipoprotein E gene (APOE4) is a strong genetic risk factor for Alzheimer's disease (AD) and mul

89 protein E epsilon4 (APOE4) allele is a major genetic risk factor for Alzheimer's disease (AD), and it

90 ApoE4 constitutes the most important genetic risk factor for Alzheimer's disease (AD), ApoE3

91 was designed to investigate the effect of a genetic risk factor for Alzheimer's disease (AD), Apolip

92 Apolipoprotein (apo) E4 is the major genetic risk factor for Alzheimer's disease (AD), but th

93 ApoE4 constitutes the most important genetic risk factor for Alzheimer's disease (AD), wherea

94 Apolipoprotein E (APOE) epsilon4 is a major genetic risk factor for Alzheimer's disease (AD), yet th

95 E (APOE) genotype is the strongest prevalent genetic risk factor for Alzheimer's disease (AD).

96 lipoprotein E4 (ApoE4) gene is the strongest genetic risk factor for Alzheimer's disease (AD).

97 ic studies identified ApoE4 as the strongest genetic risk factor for Alzheimer's disease (AD).

98 Apolipoprotein E4 (apoE4) is the major genetic risk factor for Alzheimer's disease (AD).

99 PICALM is a highly validated genetic risk factor for Alzheimer's disease (AD).

100 able to that of APOE epsilon4, the strongest genetic risk factor for Alzheimer's disease, and mediati

101 CD2-associated protein (CD2AP) is a leading genetic risk factor for Alzheimer's disease, but little

102 In addition to being the greatest genetic risk factor for Alzheimer's disease, expression

103 POE) epsilon4 gene allele, the highest known genetic risk factor for Alzheimer's disease, has paradox

104 Apolipoprotein E4 (apoE4) is the strongest genetic risk factor for Alzheimer's disease.

105 ation to age and the presence of the APOE E4 genetic risk factor for Alzheimer's disease.

106 is (IV) and represent the major predisposing genetic risk factor for atopic dermatitis (AD).

107 is a highly prevalent (around 20% of people) genetic risk factor for cardiovascular disease and calci

108 r, they contribute to underscore a potential genetic risk factor for cardiovascular diseases, includi

109 chromosome 17q21 locus, the strongest known genetic risk factor for childhood asthma.

110 ant suggested its potential involvement as a genetic risk factor for DCM in this family.

111 otein epsilon4 (APOE-epsilon4), a well-known genetic risk factor for dementia.

112 APOE-epsilon4 is a main genetic risk factor for developing late onset Alzheimer'

113 ygosity for the epsilon4 allele is the major genetic risk factor for developing late-onset Alzheimer'

114 mouse model of the 22q11.2 microdeletion, a genetic risk factor for developing several neuropsychiat

115 poprotein E4 (ApoE4) allele is the strongest genetic risk factor for developing sporadic Alzheimer's

116 Deletions on chromosome 22q11.2 are a strong genetic risk factor for development of schizophrenia and

117 acellular sorting receptor SORLA, is a major genetic risk factor for familial and sporadic forms of A

118 nsufficiency of progranulin (GRN) is a major genetic risk factor for frontotemporal lobar degeneratio

119 rs.SIGNIFICANCE STATEMENT SYNGAP1 is a major genetic risk factor for global developmental delay, auti

120 SYNGAP1 is a major genetic risk factor for global developmental delay, auti

121 These data point to kdsr as a novel genetic risk factor for hepatic injury.

122 tic protein receptor 2 ( Bmpr2) are the main genetic risk factor for heritable pulmonary arterial hyp

123 5 (GPR65) has recently been reported to be a genetic risk factor for IBD.

124 4) genotype has been identified as the major genetic risk factor for late onset Alzheimer's disease (

125 The most significant genetic risk factor for late onset Alzheimer's disease i

126 polipoprotein E (apoE) gene is the strongest genetic risk factor for late-onset AD.

127 E (APOE) epsilon4 gene allele, the strongest genetic risk factor for late-onset AD.

128 polipoprotein E (APOE) gene is the strongest genetic risk factor for late-onset Alzheimer disease.

129 APOE4 is the strongest genetic risk factor for late-onset Alzheimer disease.

130 kground Apolipoprotein E4 (APOE4) is a major genetic risk factor for late-onset Alzheimer disease.

131 e of apolipoprotein E (APOE) is the dominant genetic risk factor for late-onset Alzheimer's disease (

132 erin (CLU) gene is the third strongest known genetic risk factor for late-onset Alzheimer's disease (

133 The APOE epsilon4 allele is the strongest genetic risk factor for late-onset Alzheimer's disease (

134 possession of two apoE4 alleles is a strong genetic risk factor for late-onset Alzheimer's disease (

135 As the epsilon4 allele of APOE is the major genetic risk factor for late-onset Alzheimer's disease,

136 -In-Schizophrenia-1 (DISC1), a well-accepted genetic risk factor for mental illness, display abnormal

137 The HLA-DR15 haplotype is the strongest genetic risk factor for multiple sclerosis (MS), but our

138 intronic variant in ANKRD55, rs6859219, is a genetic risk factor for multiple sclerosis, but the biol

139 eptor subunit gene (CHRNA5) is the strongest genetic risk factor for nicotine dependence in European

140 F2) loss-of-function variant rs58542926 is a genetic risk factor for nonalcoholic fatty liver disease

141 erebrosidase (GCase), are the most important genetic risk factor for Parkinson disease (PD).

142 ene mutated in Gaucher disease, are a common genetic risk factor for Parkinson disease, although the

143 Because GBA1 mutations are the most common genetic risk factor for Parkinson disease, dopaminergic

144 tations in the GBA1 gene are the most common genetic risk factor for Parkinson's disease (PD) and dem

145 er Gaucher's disease (GD), are the strongest genetic risk factor for Parkinson's disease (PD) known t

146 for Gaucher disease (GD) are the most common genetic risk factor for Parkinson's disease (PD).

147 encodes GCase have been uncovered as a major genetic risk factor for Parkinson's disease (PD).

148 iciency in GBA constitutes the largest known genetic risk factor for Parkinson's disease.

149 h cause Gaucher disease, are the most common genetic risk factor for PD, underscoring the importance

150 MEIS1 was confirmed as the strongest genetic risk factor for restless legs syndrome (odds rat

151 Variation at HLA_DQA1-DQB1 is the major genetic risk factor for RHD in Aboriginal Australians st

152 The first genetic risk factor for SCAD was identified in the large

153 of a model of the 22q11.2 deletion, a strong genetic risk factor for schizophrenia (SCZ).

154 -threshold calcium channels, implicated as a genetic risk factor for schizophrenia.

155 ations in GBA1 are now the most common known genetic risk factor for several Lewy body disorders, and

156 Apolipoprotein E4 (ApoE4) is a major genetic risk factor for several neurodegenerative disord

157 Apolipoprotein E4 (ApoE4) is the largest genetic risk factor for sporadic AD and contributes to A

158 protein E (APOE) E4 isoform is the strongest genetic risk factor for sporadic Alzheimer disease (AD).

159 otein E (APOE) varepsilon4 allele is a major genetic risk factor for sporadic Alzheimer's disease (AD

160 expressing the human APOE4 allele, the main genetic risk factor for sporadic MCI/AD, display impaire

161 SORLA has been identified as a genetic risk factor for sporadic, but recently also for

162 enzyme in polyamine catabolism and a primary genetic risk factor for suicidality.

163 plex haplotype represents the most prevalent genetic risk factor for the development of autoimmune di

164 e deficient in Gaucher disease, are a common genetic risk factor for the development of Parkinson dis

165 Numerically, the most important genetic risk factor for the development of Parkinson dis

166 in Gaucher's disease (GD) and are the major genetic risk factor for the development of Parkinson's d

167 11.2 locus have been established as a strong genetic risk factor for the development of schizophrenia

168 effect on brain physiology and may present a genetic risk factor for the development of seizures and

169 E, whose epsilon4 isoform is the most common genetic risk factor for the disease.

170 d in schizophrenia 1 (DISC1) is an important genetic risk factor for these disorders.

171 Factor V Leiden (F5(L) ) is a common genetic risk factor for venous thromboembolism in humans

172 AT deficiency is an infrequently encountered genetic risk factor for VTE, and different subtypes vary

173 Most genetic risk factors for ACD have been identified in Eur

174 Abeta accumulation and arises downstream of genetic risk factors for AD and aberrant metabolic pathw

175 These data link three genetic risk factors for AD and reveal a possible mechan

176 t studies showing the differential effect of genetic risk factors for AD on brain functional connecti

177 However, the recent identification of genetic risk factors for AD promises to provide new insi

178 the hypothesis that there is a link between genetic risk factors for AD, cellular metabolic stress,

179 the recent identification of immune-related genetic risk factors for AD, including coding variants i

180 Genetic risk factors for adult-onset asthma are largely

181 should yield unprecedented insights into the genetic risk factors for aneuploidy.

182 D), but the functional consequences of these genetic risk factors for ASD are unknown.

183 umber variants (CNVs) have emerged as robust genetic risk factors for ASD, but not all CNV carriers e

184 Here we discuss the unique and shared genetic risk factors for atopic disorders in the context

185 Genetic risk factors for autism spectrum disorder (ASD)

186 Almost all genetic risk factors for autism spectrum disorders (ASDs

187 icted to target multiple genes implicated as genetic risk factors for BD, are increased in postmortem

188 To identify genetic risk factors for breast cancer in women of Afric

189 igned to efficiently study environmental and genetic risk factors for breast cancer.

190 isk, at present no well-established specific genetic risk factors for CAD have been elucidated.

191 We identify three novel genetic risk factors for candidaemia, which we subsequen

192 re seronegative but have villous atrophy and genetic risk factors for celiac disease must undergo end

193 domized controlled trial of 230 infants with genetic risk factors for celiac disease, we did not find

194 year prospective study of 1339 children with genetic risk factors for celiac disease, we found the cu

195 Identifying genetic risk factors for CIAG could enable safer and mor

196 ciation studies (GWASs) have identified many genetic risk factors for CKD.

197 .2 deletion syndrome, one of the most common genetic risk factors for cognitive dysfunction and schiz

198 de association studies (GWASs) aim to detect genetic risk factors for complex human diseases by ident

199 arned much about intellectual disability and genetic risk factors for congenital heart disease.

200 th chronic pancreatitis (CP) frequently have genetic risk factors for disease.

201 s allows the dissection of moderate and mild genetic risk factors for disease.

202 interact in surprising ways with well-known genetic risk factors for disorders of the nervous system

203 prior genotype data, to identify additional genetic risk factors for gallstone disease.

204 We review the genetic risk factors for late-onset Alzheimer's disease

205 We conclude that genetic risk factors for MDD and loneliness act pleiotro

206 he medical morbidity pattern associated with genetic risk factors for MDD and loneliness by conductin

207 pared with Parkinson disease (PD), potential genetic risk factors for mild parkinsonian signs have be

208 were larger in the cohort bearing the major genetic risk factors for MS (female sex and HLA risk hap

209 Few genetic risk factors for neural tube defects are known i

210 Here, we perform the first evaluation of genetic risk factors for osteonecrosis in children <10 y

211 Among the known genetic risk factors for Parkinson disease, mutations in

212 Mutations in LRRK2 and GBA1 are common genetic risk factors for Parkinson's disease (PD) and ma

213 roidal neovascularization (CNV) subtype, the genetic risk factors for PCV are relatively unknown.

214 Several genetic risk factors for POAG and optic nerve features h

215 To discern differences in genetic risk factors for PsA and cutaneous-only psoriasi

216 The identification of genetic risk factors for PTSD may provide important insi

217 lay an acknowledged role in the strongest of genetic risk factors for schizophrenia, 22q11.2 deletion

218 between neuroanatomical phenotypes and known genetic risk factors for schizophrenia.

219 drome (22q11DS) is among the strongest known genetic risk factors for schizophrenia.

220 We aimed to discover new genetic risk factors for sCJD, and their causal mechanis

221 R620W variant of PTPN22 is one of the major genetic risk factors for several autoimmune disorders in

222 association studies are identifying multiple genetic risk factors for several diseases, but the funct

223 in the HLA region remain the most important genetic risk factors for T1D, other non-HLA genetic fact

224 nel subunit genes are strongly implicated as genetic risk factors for the development of schizophreni

225 on patients >/=10 years of age, leaving the genetic risk factors for the larger group of children <1

226 ssociation study with the aim of identifying genetic risk factors for this disorder.

227 n conclusion, our study reveals novel common genetic risk factors for VTE, stroke and CAD and provide

228 ed 77-SNP polygenic risk score (PRS) and non-genetic risk factors for YOBC.

229 Genetic risk factors frequently affect multiple common h

230 tates cross-study analysis to discover novel genetic risk factors, gene-disease associations, potenti

231 Aiming to investigate whether genetic risk factors (GRFs) for fracture and bone minera

232 Whether they also differ with respect to genetic risk factors has not been previously investigate

233 (venous thromboembolism, VTE), biomarkers or genetic risk factors have not been identified.

234 ular hypertension and glaucoma, but specific genetic risk factors have yet to be identified.

235 cancer deaths, yet there have been few known genetic risk factors identified, the best known of which

236 A study of the genetic risk factors identifying patients in whom aspara

237 PRS alone and in combination with other non-genetic risk factors, (ii) estimation of lifetime risk t

238 Disrupted-In-Schizophrenia 1 (DISC1), a genetic risk factor implicated in major mental disorders

239 NPAS3 has been established as a robust genetic risk factor in major mental illness.

240 gnition receptor that is the strongest known genetic risk factor in the pathogenesis of Crohn disease

241 HLA-B*51 was confirmed as a genetic risk factor in this group (p = 0.0006, Bonferron

242 r effects, suggesting a greater role for non-genetic risk factors in adult-onset asthma.

243 o examined in population studies to identify genetic risk factors in complex traits and to predict ev

244 actors for pancreatic cancer, especially the genetic risk factors in high-risk individuals and curren

245 he use of childhood clinical factors and the genetic risk factors in predicting adulthood obesity usi

246 To search for genetic risk factors in SUDEP cases, we performed an exo

247 ave sought to explore the impact of multiple genetic risk factors in the context of different biologi

248 While the role of genetic risk factors in the etiology of uveal melanoma (

249 enesis have been indicated by the identified genetic risk factors, including type I interferon signal

250 hat of polygenicity, meaning that many small genetic risk factors influence risk in the population an

251 The strongest genetic risk factor influencing susceptibility to late-o

252 f differences in clinical, socioeconomic, or genetic risk factors is unknown.

253 But how this relates to specific genetic risk factors is unknown.

254 between these traits, including the role of genetic risk factors, is complex and poorly understood.

255 f depression including its environmental and genetic risk factors, its association with the acute pha

256 to be a major hindrance to the discovery of genetic risk factors, leading to numerous attempts to st

257 fferences in how the striatum is impacted by genetic risk factors linked to neurodevelopmental disord

258 nue to suffer from ADHD during adulthood and genetic risk factors may play an essential role in the p

259 s have applications in the identification of genetic risk factors, medical diagnostics, and environme

260 the involvement of FERMT2 (or Kindlin-2), a genetic risk factor of Alzheimer's disease (AD), as a po

261 PLG is the third replicated shared genetic risk factor of atherosclerosis and periodontitis

262 BIN1 is a genetic risk factor of late-onset Alzheimer disease (AD)

263 Genetic risk factors often localize to noncoding regions

264 ility loci and show that CBD and PSP share a genetic risk factor other than MAPT at 3p22 MOBP (myelin

265 the absence of any statistically significant genetic risk factor other than the common autoimmune dis

266 n that svPPA is a clinical syndrome with few genetic risk factors, our analyses show that svPPA risk

267 Although faithful modeling of a genetic risk factor poses many challenges, the different

268 However, it is unclear whether genetic risk factors predispose individuals to autism as

269 cent data suggest that common modifiable and genetic risk factors predispose to both malignancies and

270 lopment of IPF; however, mechanisms by which genetic risk factors promote IPF remain unclear.

271 ce Taken together, our findings confirm that genetic risk factors related to the presence of GA are n

272 the US Million Veteran Program, to identify genetic risk factors relevant to intrusive reexperiencin

273 explain disease heritability, and additional genetic risk factors remain to be discovered.

274 hether HCC and psychological variables share genetic risk factors remains unclear.

275 Alzheimer's disease and recent evidence for genetic risk factors specifically related to posterior c

276 for the A1AT Z-allele with environmental or genetic risk factors such as steatosis or heterozygosity

277 the precise nature of which is specified by genetic risk factors, such as HLA alleles.

278 lity led to the identification of a specific genetic risk factor that approached genome-wide signific

279 dren with sickle cell anemia and represent a genetic risk factor that is potentially modifiable by bo

280 me as an interface between environmental and genetic risk factors that are associated with ASD.

281 provides evidence for both shared and unique genetic risk factors that are associated with iron-relat

282 In this study, our aim was to identify genetic risk factors that contribute to progression from

283 complex disease with both environmental and genetic risk factors that contribute to the arrhythmia.

284 upport the need for further investigation of genetic risk factors that modulate initiation and progre

285 tification of cultural, epidemiological, and genetic risk factors that predispose women of African an

286 udy of inherited forms of early-onset AD and genetic risk factors that provide insights about molecul

287 Despite recent discoveries of new genetic risk factors, the majority of risk for coronary

288 We aimed to identify further shared genetic risk factors to better understand conjoint disea

289 ization of molecular mechanisms that connect genetic risk factors to initiation and evolution of dise

290 Our understanding of the contribution of genetic risk factors to neuropsychiatric diseases is lim

291 to gain a better understanding of the use of genetic risk factors to predict treatment outcome.

292 contribution of clinical, pathological, and genetic risk factors to transformation.

293 ion with Lynch syndrome, the contribution of genetic risk factors to UC pathogenesis has not been sys

294 At least one identifiable genetic risk factor was found in 72.1% of the patients,

295 ociated variant P2X7R-Gln460Arg represents a genetic risk factor, which is potentially able to convey

296 We find that most diseases are dominated by genetic risk factors, while environmental influences pre

297 anistically link an immunologically relevant genetic risk factor with a functional feature of TH cell

298 terization, we established p.G411S as a rare genetic risk factor with a relatively large effect size

299 a polygenic disorder that shares substantial genetic risk factors with major depressive disorder (MDD

300 Identification of previously unknown genetic risk factors would provide mechanistic insights