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1 of the most widely used model organisms for genetic study.
2 accuracy and reproducibility of the trial or genetic study.
3 al is also found with genes from independent genetic studies.
4 to be within the range of those estimated in genetic studies.
5 binary phenotypes that can improve power for genetic studies.
6 ch as genome-wide association and population genetic studies.
7 um) genetic maps are a key enabling tool for genetic studies.
8 ally low, limiting its utility in functional genetic studies.
9 ational efforts to increase the diversity of genetic studies.
10 fully pave the way for future evidence-based genetic studies.
11 xtending what we have learned from classical genetic studies.
12 nificant advantages of the murine system for genetic studies.
13 infections and can be used for retrospective genetic studies.
14 an transmit genetic information, restricting genetic studies.
15 mples are a common source of DNA in wildlife genetic studies.
16 rols for hypertension in epidemiological and genetic studies.
17 h combining high-throughput phenotyping with genetic studies.
18 kade of SEMA4C in vitro mirrored that of the genetic studies.
19 more global representation of populations in genetic studies.
20 ill help enable the next generation of human genetics studies.
21 als is widely used in clinical and molecular genetics studies.
22 ithms have been proposed and used in imaging genetics studies.
23 rker in genetic association and evolutionary genetics studies.
24 a powerful tool for both forward and reverse genetics studies.
25 ys) are fundamental resources for functional genetics studies.
27 arkers discovery is also provided, including genetic studies and available information on transcripto
29 to be an important trait to target in future genetic studies and breeding schemes, to help reducing t
33 p and a valuable genomic resource for future genetic studies and improved genome-assisted breeding of
34 B infestation, yet few genomic resources for genetic studies and improvement of green ash are availab
35 risk scores is a consequence of Eurocentric genetic studies and limited knowledge of shared causal v
36 his offers a complementary resource to human genetic studies and predict that many more genes could b
37 Orinoco river basins, yet few resources for genetic studies and the genetic improvement of tambaqui
40 ds, (ii) power calculations for multivariate genetic studies, and (iii) generating data for testing a
43 RS, greater diversity must be prioritized in genetic studies, and summary statistics must be publical
46 heritability remains unexplained, and large genetic studies are warranted to identify new susceptibi
50 diversity but are not routinely analyzed in genetic studies because they are difficult to accurately
51 We addressed this question in a parallel genetic study between the closely related species Arabid
52 ASD pathogenesis have been proposed based on genetic studies, brain pathology and imaging, but a majo
54 te or are frozen, and opens the way to human genetics studies, clinical trials, and precise cell atla
60 loss of tRNA aminoacylation function, animal genetics studies demonstrated that dominant mutations in
61 shark species for ecological and population genetic studies, enabled accurate identification of the
65 risk genes and loci identified through human genetic studies far outstrips the capacity to systematic
67 hypothesis-driven approaches, using previous genetic studies for polygenic risk, or other PTSD-relate
76 elopment of vascular complications; numerous genetic studies have demonstrated a clear genetic compon
91 ions account for 85-90% of GISTs; subsequent genetic studies have led to the identification of mutati
95 ed and seemingly dysfunctional with age, and genetic studies have linked these cells to the pathogene
98 lar genetic tools, a large number of reverse genetic studies have propelled the use of this model sys
100 wever recent structural, pharmacological and genetic studies have provided new insight into the regio
101 lated behaviors.SIGNIFICANCE STATEMENT Human genetic studies have provided strong evidence for a rela
109 st and North Africa, and previous population genetic studies have shown genetic differentiation betwe
115 an and American wolves and domestic dogs.(1) Genetic studies have suggested these groups trace their
119 w draws upon multiple lines of evidence from genetic studies, human tissue, induced pluripotent stem
123 c analysis combined with pharmacological and genetic studies identified Notch3 as a promoter of tumor
128 hologic correlation of cutaneous lesions and genetic studies in 11 members of a family with familial
131 cytic differentiation, we performed detailed genetic studies in acute myeloid leukemia (AML) cells.
132 r nectar secretion has been established from genetic studies in Arabidopsis (Arabidopsis thaliana); h
134 the Integrin receptor complex, we conducted genetic studies in Drosophila nephrocytes and validated
135 suppresses starvation-induced autophagy, and genetic studies in Drosophila reveal that RagC phosphory
138 recurring theme emerging from developmental genetic studies in grass models, that is that infloresce
140 ent strategy should be widely applicable for genetic studies in many taxa, particularly those ~20 mil
142 Here, using lineage-tracing and molecular genetic studies in the roots of Arabidopsis thaliana, we
144 itative genetic variability for breeding and genetic studies in yam and other root and tuber crops.
146 or and how this approach quickly merged with genetic studies in yeast to establish the basic mechanis
149 genes implicated in AD by previous brain and genetic studies, in humans and animal models, which serv
150 tions using PCR amplification is key to many genetic studies, including studying tumor heterogeneity,
151 subject to the same constraints as any other genetic study, including stringent type I error control.
160 roprotective activity.SIGNIFICANCE STATEMENT Genetic studies indicate that TREM2 gene mutations confe
166 1 genome is presented as a reference for any genetic studies involving Ashkenazi Jewish individuals.
171 ., observational studies, animal models, and genetic studies, is necessary given limits of human popu
172 Maize (Zea mays L.), a model species for genetic studies, is one of the two most important crop s
174 ighlights the limited utility of the current genetics studies largely focused on people of European d
176 use of its structural similarity to glucose, genetic studies of 1,5-AG can deliver complementary insi
178 preclinical mouse models of liver cancer and genetic studies of a human liver biopsy atlas with the a
179 )-enabled image-phenotyping pipeline for the genetic studies of abiotic stress iron deficiency chloro
180 developed novel causal inference methods for genetic studies of AD and T2DM and pipelines for systema
181 tructural, biochemical, cell biological, and genetic studies of any gene/protein are required to deve
182 fied should prove valuable for more detailed genetic studies of arapaima populations, including the e
185 cations of increasing ancestral diversity in genetic studies of cardiometabolic disease and the chall
188 cipate that GWAX will prove useful in future genetic studies of complex traits in large population co
191 ideas fell by the wayside with the advent of genetic studies of embryogenesis, they demonstrated that
193 and developmental biology, the ways in which genetic studies of flowering time diversity have enriche
196 dely used, although more recent clinical and genetic studies of higher quality are now available.
197 s a precise genetic engineering platform for genetic studies of hMSCs and development of engineered h
198 Consistent with this finding, large-scale genetic studies of humans reveal a significant associati
204 ders share several genetic associations, and genetic studies of major depressive disorder and bipolar
213 ulate the genomic risk scores based on large genetic studies of six phenotypes: major depressive diso
215 WE test fills an important gap in population genetic studies of tetraploids related to their evolutio
223 So far, to our knowledge, no large-scale genetic study of dementia with Lewy bodies has been done
225 s the utility of extreme trait selection for genetic study of intelligence and suggests that extremel
229 ce and further epidemiological and molecular genetic study of this potential emergent antimicrobial p
231 on described here should be valuable for the genetic study of V. cholerae and could be adapted for us
238 ed genome sequence will permit sophisticated genetic studies on stem cells and regeneration using M.
245 pathophysiology of schizophrenia, including genetic studies reporting associations with glutamatergi
256 s will be useful in different areas of human genetic studies, such as annotation-based casual variant
266 rs, directly confirmed by the past decade of genetic studies that have revealed specific genetic vari
267 ey genes and loci from animal and human host genetic studies that may bear investigation in the study
272 ew, we first consider the history of mice in genetic study, the development of classic approaches to
273 e editing has enabled large-scale functional genetic studies through the generation of gene knockouts
274 combined quantitative mass spectrometry and genetic studies to analyze the components and the activi
275 Tsr residue Thr156, which has been shown by genetic studies to be critical for the attractant respon
276 (RD) is a serious and common condition, but genetic studies to date have been hampered by the small
278 now allow mechanistic studies to move beyond genetic studies to identify the promoters and enhancer r
279 In the present study, we conducted a human genetic study to assess the association of EFNB3 single
281 ubiquitously used within bioinformatics and genetics studies to convey critical information about re
284 the methodology can also be used to conduct genetic studies using high-dimensional phenotypes that a
289 Using microfluidics and pharmacological and genetic studies, we could recapitulate high shear stress
296 ct with COP1, and biochemical, molecular and genetic studies were carried out to elucidate the regula
297 gle-cell imaging experiments, and functional genetic studies, which provide an increasingly complex v
298 stigation, common to functional neuroimaging genetics studies, which could have yielded elevated fals
300 y overlap regions linked to stature in human genetic studies, with a disproportionate number of these