ライフサイエンスコーパス: genogroup

1 nd are likely members of a new mamastrovirus genogroup.

2 uctures have only been determined for the GI genogroup.

3 e level, that comprise a single genotype and genogroup.

4 s comprising two clusters within a third NLV genogroup.

5 cies now called the Ehrlichia phagocytophila genogroup.

6 cificity of each IgM test for its respective genogroup.

7 d to members of the Ehrlichia phagocytophila genogroup.

8 , with >=80% of infections caused by the GII genogroup.

9 ex on the long-term prognosis per underlying genogroup.

10 meningitidis and individual disease-causing genogroups.

11 in that is highly conserved across norovirus genogroups.

12 omobacter species and revealed 14 additional genogroups.

13 that were conserved within genoclusters and genogroups.

14 capsid protein sequences, and comprise three genogroups.

15 e NoV NS3 proteins among the seven Norovirus genogroups.

16 the clinical isolates were placed into three genogroups.

17 acted more strongly than did strains between genogroups.

18 the VP6 amplicons revealed two clusters, or genogroups.

19 The clinical isolates clustered into 21 genogroups.

20 lity of vaccines to neutralize the different genogroups.

21 luate the antigenic relatedness of different genogroups.

22 r infected birds to neutralize the different genogroups.

23 on with human noroviruses from two different genogroups.

24 ncoding porin protein A) and N. meningitidis genogroups.

25 cific cleavage sites both within and between genogroups.

26 ding specificities of noroviruses from other genogroups.

27 519-527)]) was highly conserved among all NV genogroups.

28 NV2461 was found to occur in the majority of genogroup 1 (G1) but not genogroup 2 (G2) "Norwalk-like

29 ) infections were 3 times more frequent than genogroup 1 (GI) infections.

30 , we report the first complete sequence of a genogroup 1 avian bornavirus (ABV1).

31 Furthermore, an anti-genogroup 1 human TTV antiserum did not react with any o

32 gG nor salivary IgA cross-reacted with NV, a genogroup 1 norovirus.

33 36 G1P[8], 18 G3P[8], and 4 G12P[8] Wa-like genogroup 1 strains with VP6-VP1-VP2-VP3-NSP1-NSP2-NSP3-

34 owed that they were human calicivirus (HuCV) genogroup 1 viruses related, but not identical, to NV.

35 rwalk virus, a prototype member of Norovirus genogroup 1.

36 with porcine epidemic diarrhea virus (PEDV) genogroups 1 (G1) or 2 (G2).

37 s) correlated with a known species, and nine genogroups (17 strains) did not.

38 in the majority of genogroup 1 (G1) but not genogroup 2 (G2) "Norwalk-like viruses" (NLVs).

39 In multivariate analysis, genogroup 2 genotype 4 (GII.4) NoV strains were associat

40 oss-reactive with Hawaii virus (HV), another genogroup 2 norovirus, salivary IgA was less cross-react

41 challenged with Snow Mountain virus (SMV), a genogroup 2 norovirus.

42 Genogroup 2 type 4 (GII.4) has been the dominant norovir

43 are representative of the genera Norovirus (genogroup 2), Sapovirus, and Vesivirus, respectively.

44 Genogroup 24 was predominant.

45 dimerization appears to be unique within the genogroup 2c and may potentially increase the complexity

46 sion following introduction of a full-length genogroup 3 norovirus genome into HepG2 cells.

47 ding frames, a feature that may be unique to genogroup 3 noroviruses.

48 Twelve genogroups (74 strains) correlated with a known species,

49 The prevalence of genogroup A fell from 0.7% to 0.02% in Chad following ma

50 ride capsules; genogroup W predominated, and genogroup A was rare.

51 Disease-associated meningococci (genogroups A, B, C, W, X, Y) were detected by meningococ

52 d (serologically nongroupable); by PCR-based genogrouping, a quarter of these belonged to the capsula

53 tes were also found that corresponded to the genogroup A2 variant identified in New York and Australi

54 likely more closely antigenically related to genogroups A3 and A4 than A6 and A8.

55 linkage disequilibrium in all of the species/genogroups able to be tested, indicating that each group

56 e activity in some individuals but not cross-genogroup activity.

57 d by polymerase chain reaction for norovirus genogroup and genotype.

58 s classified the recovirus isolates into two genogroups and at least four genetic types.

59 me polymerase chain reaction, along with TTV genogroups and coinfection with HEV.

60 protein function within different Norovirus genogroups and expands a growing knowledge base on the i

61 characterized by antigenic variation between genogroups and genotypes and antigenic drift of strains

62 To determine the genogroups and genotypes of bovine enteric caliciviruses

63 The distributions of genogroups and of capsule-null organisms were similar wi

64 ports the subdivision of human NLVs into two genogroups and provides an assay for the rapid identific

65 ility of vaccines to neutralize diverse IBDV genogroups and to better understand the relationship bet

66 coinfections with distinct BECV genotypes or genogroups, and describe the first natural BoNV genotype

67 . chaffeensis, each belonging to a different genogroup, are inoculated into severe combined immunodef

68 A potent EV71 genogroup B- and virus-specific ASC response was detecte

69 ovirus, which is comprised of at least three genogroups based on sequence differences.

70 We tentatively classified SaVs into 14 genogroups based on the complete capsid protein VP1.

71 No clear segregation of species/genogroups between CF and non-CF sources was found.

72 However, we found three genogroups by gene sequence analysis.

73 cross-reactive EV71-specific ASC response to genogroup C viral antigens composed about 10% of the res

74 o belong to a novel genogroup of rhinovirus, genogroup C.

75 phages differentiate EHEC O157 isolates into genogroups commonly isolated from cattle but rarely from

76 hly divergent strains suggested that the MNV genogroup comprises a single serotype.

77 he 16S ribosomal DNA (rDNA) of the Ehrlichia genogroup comprising E. equi, E. phagocytophila, and the

78 roduced disease in the SCID mouse model, and genogroup-consistent trends were noted in cytokine produ

79 Our results indicate that hNoVs exhibit genogroup dependent resistance and that disinfection pra

80 Although genogroup-dependent variation in HBGA binding specificit

81 Capsular genogroups detected by broth culture were genogroups W (

82 One MAb had broad cross-genogroup EIA reactivity to a nonblockade, linear, conse

83 y sought, none have been reported for the GI genogroup, first described more than 50 years ago.

84 two major genogroups (GI and GII), with each genogroup further divided into multiple genotypes.

85 groups (genogroup I [GI] and GII), with each genogroup further divided into several genotypes.

86 nto seven genogroups (GI to GVII), with each genogroup further divided into several genotypes.

87 ol can be used to study viral replication of genogroup (G)I and GII HuNoVs in vivo within 3-4 d.

88 oeae multi-antigen sequence typing (NG-MAST) genogroup, G12302 (132 [5.6%] of 2375; N gonorrhoeae seq

89 ly clonal population, with most belonging to genogroup G1407 and harbouring the penA mosaic gene.

90 Human NoVs are classified into two major genogroups (genogroup I [GI] and GII), with each genogro

91 ining at least 31 genotypes in the two major genogroups (genogroup I [GI] and GII).

92 evivirus), which can be subdivided into four genogroups (genogroups I and II in Levivirus and genogro

93 The concentrations of NoV genogroups (GG) I and II in samples collected at WWTPs a

94 V71 variants have been classified into three genogroups (GgA, GgB, and GgC), and the latter two are f

95 Although designed for NV, a genogroup GI.1 norovirus, NoroGLuc also efficiently dete

96 ction and typing of NoV strains belonging to genogroups GI and GII and adapted them to the LightCycle

97 Structures of noroviruses from genogroups GI and GII in complex with HBGAs, however, re

98 They are classified into two major genogroups (GI and GII), with each genogroup further div

99 They are divided into seven genogroups (GI to GVII), with each genogroup further div

100 variable and have been classified into four genogroups (GI, -II, -IV, and -V).

101 es and one novel cluster (n = 5) within four genogroups (GI, GII, GIV, and GV) were identified by phy

102 m a diaper-changing station in the restroom (genogroup GII).

103 Replication of HuNoV genogroup GII.3 strain U201 RNA, generated from a revers

104 within GII) and SaVs comprising at least two genogroups (GIII and GVI?/JJ681-like) and two unclassifi

105 Most genogroups had consistent biotypes (as determined with t

106 Each genogroup has further diverged into multiple sub-lineage

107 Eight infectious bursal disease virus (IBDV) genogroups have been identified based on the sequence of

108 Seven ABV genogroups have been identified worldwide from a variety

109 These results establish NoroGLuc as a pan-genogroup HuNoV protease reporter system that can be use

110 A total of 435 outbreaks (11%) were typed as genogroup I (GI) and 3,525 (89%) as GII noroviruses.

111 mine if virus-like particles (VLPs) of HuNoV genogroup I (GI) and GII bind to A- or H-type tissues; (

112 eres were coupled to recombinant antigens of genogroup I (GI) and II (GII) noroviruses and incubated

113 l studies have shown increased prevalence of genogroup I (GI) NoVs.

114 ifferences within the P2 domain of norovirus genogroup I (GI) strains can be used to segregate outbre

115 ile (12.6 to 13.9% prevalence) and norovirus genogroup I (GI)/GII (5.7 to 13.9% prevalence) were two

116 Noroviruses were genetically diverse: both genogroup I (GI.2, GI.5 and GI.6) and genogroup II (GII.

117 capsid protein or P domain mutants from both genogroup I (Norwalk virus) and genogroup II (VA387) nor

118 iation was particularly strong for norovirus genogroup I (NoV-GI) and between adult AGI and enterovir

119 li (OR: 1.65; 95% CI: 1.10, 2.46), norovirus genogroup I (OR: 1.66; 95% CI: 1.23, 2.25), and Giardia

120 Vs are classified into two major genogroups (genogroup I [GI] and GII), with each genogroup further d

121 st 31 genotypes in the two major genogroups (genogroup I [GI] and GII).

122 genogroup II (GII) infection was higher than genogroup I and peaked at 6-11 months across sites.

123 hat strain fr should be grouped in Levivirus genogroup I and that the MX1 and M11 strains belong in A

124 Genogroup I comprised the M. szulgai type strain, all th

125 suitable for diagnosis of NV and other HuCV genogroup I infections and is especially useful when ser

126 ve IgM, indicating test specificity for HuCV genogroup I infections.

127 d volunteers and from patients involved in a genogroup I NLV outbreak were also tested.

128 ses to the major capsid protein from another genogroup I NLV strain (NCFL) isolated from a recent out

129 Norwalk virus (NV) is the prototype genogroup I norovirus that specifically recognizes A- an

130 ding Norwalk Virus capsid protein (a related Genogroup I Norovirus) in transiently transfected plants

131 m the N-terminal protein of Norwalk virus (a genogroup I norovirus) or MD145 (a genogroup II noroviru

132 alysis, is highly conserved, but only in the genogroup I noroviruses, suggesting that a mechanism by

133 Sera from genogroup I Norwalk virus (NV)-inoculated volunteers and

134 f the Seto virus (SeV), a Japanese strain of genogroup I Norwalk-like viruses (NLVs), was expressed a

135 ns were the most abundant (79%), followed by genogroup I NoV strains (19%) and sapovirus (2%).

136 oV-positive stool samples were identified as genogroup I NoVs, and time spent at travel destinations

137 In sera from those infected with genogroup I NV or NLVs in volunteer and outbreak studies

138 am were positive for a Norwalk-like virus of genogroup I on RT-PCR assay; the RT-PCR products had ide

139 d IgGs reactive with human norovirus (HuNoV) genogroup I or II (GI or GII).

140 ontrast to the MSP2 homologues in ehrlichial genogroup I pathogens, Ehrlichia chaffeensis, Ehrlichia

141 V and the prototype human strain 1-CHN-97 of genogroup I PBVs and an even lower similarity (38.4%) to

142 We now report the detection of genogroup I PBVs in 48% (44/92) of the fecal specimens b

143 Astrovirus type 1 (37.7%) and genogroup I sapoviruses (59.3%) were most prevalent.

144 Although genogroup I strain fr and genogroup III strains MX1 and

145 trains were the predominant type (73%), with genogroup I strains causing 26% of all NLV-positive outb

146 Avidities to heterotypic genogroup I VLPs were not sustained at day 35 after vacc

147 o genetic lineages were distinguished within genogroup I, consisting of strains serologically charact

148 gainst the vaccine's prototype Norwalk virus/genogroup I, genotype 1 (GI.1) (P1) virus strain.

149 Genogroup I, genotype 1 (GI.1)-specific HBGA-blocking an

150 virus-like particles (VLPs) derived from NV (genogroup I, GI) and MD145 (genogroup II, GII) norovirus

151 s on the norovirus capsid protein for both a genogroup I-cross-reactive monoclonal antibody and a gen

152 Although the genogroup I-cross-reactive monoclonal antibody was previ

153 stomach biopsy specimens, as well as that of genogroup I.1 and genogroup II.4 virus-like particles, w

154 ototype norovirus strain Norwalk virus (NV) (genogroup I.1).

155 ression and self-assembly of newly developed genogroup I/II chimeric VLPs showed that five MAbs bound

156 st between proteases from human noroviruses (genogroups I (GI) and II) and the commonly used murine n

157 genogroups, with human strains grouped into genogroups I (GI), II, and IV.

158 g HuNVs of 4 and 10 genetic subgroups within genogroups I and II (GI and GII), respectively, and 39 s

159 e detection and differentiation of norovirus genogroups I and II (GI and GII), which account for the

160 hich can be subdivided into four genogroups (genogroups I and II in Levivirus and genogroups III and

161 Human noroviruses in genogroups I and II interact with histo-blood group anti

162 Six distinct genetic clusters within genogroups I and II of the NLVs were detected; a genogro

163 tide similarities among strains of Levivirus genogroups I and II were 75% to 99% and 83 to 94%, respe

164 ovirus (types 1, 2, 3, 4, and 8), sapovirus (genogroups I and II), parechovirus (types 1, 3, 4, and 5

165 s in both binding group can be found in both genogroups I and II.

166 the human norovirus strains classified into genogroups I and II.

167 1 (AiV-1), enteroviruses, and noroviruses of genogroups I, II, and IV] were tested by quantitative PC

168 0), with the majority of positives caused by genogroup II (82%, n = 74).

169 NoVs that belong to genogroup II (GII) are quite prevalent and prone to unde

170 Incidence of genogroup II (GII) infection was higher than genogroup I

171 Genogroup II (GII) infections were 3 times more frequent

172 ) to analyze the interaction of citrate with genogroup II (GII) noroviruses.

173 Porcine genogroup II (GII) NoVs replicate in pigs, but their pat

174 argeting the 5' end of the capsid region for genogroup II (GII) NoVs, a group which includes human No

175 Genogroup II (GII) strains were the predominant type (73

176 groups I and II of the NLVs were detected; a genogroup II (GII) virus closely related to the Camberwe

177 We quantified adenovirus, norovirus genogroup II (GII), and F+ coliphage in the influent was

178 Norovirus-specific IgG antibodies to genogroup II (GII)-4-2010 New Orleans (NO), GII-4-1999,

179 = 118; 85%) norovirus infections belonged to genogroup II (GII).

180 : both genogroup I (GI.2, GI.5 and GI.6) and genogroup II (GII.1-GII.4, GII.6, GII.7, GII.12, GII.14,

181 ence, severity, and seasonality of norovirus genogroup II (NVII) among children <5 years old in The G

182 identified as being caused by a recombinant genogroup II (rGII-3a) strain, fecal specimens collected

183 ts from both genogroup I (Norwalk virus) and genogroup II (VA387) noroviruses with trypsin resulted i

184 NoVs belonging to genogroup II and genotype 4 (GII.4) are globally most pr

185 Human NoVs belonging to genogroup II and genotype 4 (GII.4) are the most prevale

186 A limited number of other genogroup II and I strains were cocirculating.

187 Genogroup II comprised five pigmented strains: three wer

188 Genogroup II ehrlichia, including the agent of human gra

189 e strain structure of Anaplasma marginale, a genogroup II ehrlichial pathogen, in both an acute outbr

190 rium adolescentis (BifAd); one viral marker: genogroup II F-specific RNA bacteriophages (FRNAPH II);

191 use of acute gastroenteritis worldwide, with genogroup II genotype 4 (GII.4) noroviruses accounting f

192 s to rNV, thus establishing the diagnosis as genogroup II NLV infection.

193 A developed is specific for the diagnosis of genogroup II NLV infections.

194 outbreaks of gastroenteritis were tested for genogroup II NLV Mexico virus-specific immunoglobulin M

195 In sera from those infected with genogroup II NLVs in volunteer and outbreak studies, 28

196 and 2.2 times as likely to be infected with genogroup II non-4 noroviruses (95% CI, 1.2-4.2) compare

197 Overall, genogroup II norovirus (NoV) strains were the most abund

198 All outbreaks were caused by a genogroup II norovirus related to the Lordsdale virus (G

199 virus (a genogroup I norovirus) or MD145 (a genogroup II norovirus) was fused to the C terminus of e

200 nt-based vaccine against Narita 104 virus, a Genogroup II Norovirus.

201 Genogroup II noroviruses are the most common cause of ac

202 ecognizes A- and H-type HBGA, in contrast to genogroup II noroviruses that exhibit a more diverse HBG

203 Two genogroup II noroviruses, one representing the Toronto g

204 tained from adult volunteers inoculated with genogroup II Norwalk-like viruses (NLVs), Hawaii virus,

205 Genogroup II NVs were responsible for 83% of the outbrea

206 sby or Girlington (P < 0.0001) than by other genogroup II or I strains.

207 (38.4%) to segment 2 of the prototype human genogroup II strain 4-GA-91.

208 rsing homes were more likely to be caused by genogroup II strain Grimsby or Girlington (P < 0.0001) t

209 Noroviruses (NoVs) of genogroup II, cluster 4 (GII.4), are the most common cau

210 e genetic lineages were distinguished within genogroup II, composed of strains serologically characte

211 Rotavirus, norovirus genogroup II, Cryptosporidium, and Shigella species/ente

212 Human noroviruses (NoVs) of genogroup II, genotype 4 (GII.4) are the most common str

213 are genetically related, segregating in the genogroup II, genotype 4 (GII.4) cluster within the Noro

214 All genogroup II, genotype 4 (GII.4) infections were among s

215 t strains; and furthers our understanding of genogroup II, genotype 4 (GII.4) norovirus immune-driven

216 Genogroup II, genotype 4 (GII.4) noroviruses are known t

217 Genogroup II, genotype 4 NoVs (GII.4) remain the dominan

218 derived from NV (genogroup I, GI) and MD145 (genogroup II, GII) noroviruses as vaccines.

219 p I-cross-reactive monoclonal antibody and a genogroup II-cross-reactive monoclonal antibody by use o

220 ajority of norovirus outbreaks are caused by genogroup II.4 (GII.4).

221 CI], 3.9-24.8) as likely to be infected with genogroup II.4 noroviruses and 2.2 times as likely to be

222 A human norovirus genogroup II.4 strain HS66 (HuNoV-HS66) infects and caus

223 cimens, as well as that of genogroup I.1 and genogroup II.4 virus-like particles, were compared in a

224 gions had an annual peak in 2002 and the new genogroup II4 variant was detected in nine countries.

225 ce of a new predominant norovirus variant of genogroup II4, which had a consistent mutation in the po

226 capsid genes of Bo/CV186-OH/00/US (Norovirus genogroup III [GIII], genotype 2 [GIII/2]).

227 ese analyses, 15 BECVs belonged to Norovirus genogroup III and genotype 2 (GIII/2) and were genetical

228 Although genogroup I strain fr and genogroup III strains MX1 and M11 share only 70 to 78% s

229 The single strain (isolated in 1996) in genogroup III was pigmented and was the only strain asso

230 p antigen carbohydrates, bovine noroviruses (genogroup III) interact with alpha-galactosidase (alpha-

231 MX1 and M11 strains belong in Allolevivirus genogroup III.

232 groups (genogroups I and II in Levivirus and genogroups III and IV in Allolevivirus).

233 similarities among strains of Allolevivirus genogroups III and IV ranged from 70 to 96% and 75 to 95

234 lence of NoV diarrhea and in the predominant genogroup infecting travelers was demonstrated, dependen

235 rticles, this work shows that representative genogroup IV and VI viruses can interact with histo-bloo

236 ecific strains of norovirus are grouped into genogroups IV and VI, and this study is the first to cha

237 thogen in dogs, with strains classified into genogroups IV and VI.

238 re screened for NoV and characterized at the genogroup level (GI and GII).

239 hrlichiosis and aid in the classification of genogroup members.

240 Within this single genogroup, MNV strains exhibited considerable biological

241 Among both sporadic cases and outbreaks, GII genogroup noroviruses were most prevalent (90.1% and 83.

242 Among both sporadic cases and outbreaks, GII genogroup noroviruses were most prevalent (90.1% and 83.

243 The MLB genogroup of astroviruses represents a genetically disti

244 The P[19] genotype belongs to the P[II] genogroup of group A rotaviruses (RVs).

245 mplete capsid, we identified a potential new genogroup of porcine SaVs, with Po/SaV/OH-JJ681/00/US as

246 inovirus and were found to belong to a novel genogroup of rhinovirus, genogroup C.

247 ifficulties in the serogrouping and capsular genogrouping of meningococcal carriage isolates.

248 sistent site and disease associations for 21 genogroups of Actinomyces spp. that provide greater insi

249 nalysis of selected strains in the two major genogroups of human NoVs (GI and GII) demonstrated highl

250 Recently, at least three new genogroups of porcine SaVs have been proposed.

251 ence of symptomatic norovirus infection in a genogroup or genotype-dependent manner and provides evid

252 VP8* sequences, RVs are grouped into five P genogroups (P[I] to P[V]), of which P[I], P[IV], and P[V

253 ce identity with strains in their respective genogroups, phylogenetic analyses of the complete genome

254 VN titers against the other genogroups ranged from log(2) 9.3 to 13.3, and A1 strain

255 Strains within genogroups reacted more strongly than did strains betwee

256 e part of the hospital-associated E. faecium genogroup referred to as clonal complex 17 (CC17), which

257 The Enterococcus faecium genogroup, referred to as clonal complex 17 (CC17), seem

258 Isolate polymerase chain reaction genogrouping revealed 4 patterns: IVb (21 of 42, 50%), I

259 for the presence of Ehrlichia phagocytophila genogroup rickettsiae by using a nested PCR technique.

260 est that the prevalence of E. phagocytophila genogroup rickettsiae in ixodid ticks of California may

261 norovirus was present, after accounting for genogroup, rotavirus vaccine, and age.

262 version against GI VLPs, indicating a highly genogroup-specific antibody response.

263 viral load, fever duration, and serological genogroup-specific neutralization titer.

264 W, X, Y) were detected by meningococcal and genogroup-specific polymerase chain reaction.

265 ars in specific Asian countries representing genogroup-specific sources of EV-A71 diversity.

266 e epitope explains the monoclonal antibody's genogroup specificity.

267 Furthermore, within genogroups, sporadic recombination events occurred, such

268 ) based on their similarities to proteins of genogroup strains (Wa, DS-1, or AU-1, respectively).

269 acteristics of Haemophilus influenzae type b genogroup strains isolated from genitourinary tract spec

270 cordingly, our analysis reveals that a rapid genogroup switch from C4 to B5 likely took place during

271 nd recognition of noroviruses from different genogroups, the prototypic Norwalk virus (NV; GI-1) and

272 and the commonly used murine norovirus (MNV, genogroup V) model.

273 ha-Gal) carbohydrates, and murine norovirus (genogroup V) recognizes sialic acids.

274 disease-associated polysaccharide capsules; genogroup W predominated, and genogroup A was rare.

275 ar genogroups detected by broth culture were genogroups W (21 isolates), B (12 isolates), Y (8 isolat

276 Genogroup was reported for 7292 outbreaks with 862 (11.8

277 an VP4 and VP7 between major human rotavirus genogroups was observed.

278 Repeat infections by the same genogroup were common, but repeat infections by the same

279 ks, and strains belonging to a tentative new genogroup were identified.

280 Viral load and genogroups were influenced by immunosuppression.

281 within the same (n = 3) or different (n = 5) genogroups were observed in eight children.

282 One biotype was common to several genogroups, with all of these isolates being identified

283 etically, noroviruses are divided into seven genogroups, with each divided into multiple genotypes.

284 Noroviruses are divided into 6 genogroups, with human strains grouped into genogroups I

285 tures reveal polymorphism between and within genogroups, with small, medium, and large particle sizes

286 BEC strains detected in Europe form a third genogroup within the genus "Norwalk-like viruses" (NLV)

287 pable meningococci predominated, followed by genogroups Y, B, W, and C.