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1 equent development, in a phenomenon known as genomic imprinting.
2 oped to explain the epigenetic phenomenon of genomic imprinting.
3 be more plausible evolutionary outcomes than genomic imprinting.
4 he primary explanations for the evolution of genomic imprinting.
5 t Tet1 has a critical role in the erasure of genomic imprinting.
6 downstream factors, e.g. Pheres1 (PHE1), by genomic imprinting.
7 in-dependent gene expression associated with genomic imprinting.
8 tance of the placenta as a target tissue for genomic imprinting.
9 hat supports the parental conflict theory of genomic imprinting.
10 coadaptation can also favor the evolution of genomic imprinting.
11 mature human neurons due to tissue-specific genomic imprinting.
12 site alleles suggest that sRNAs may regulate genomic imprinting.
13 critical function of Tet1 in the erasure of genomic imprinting.
14 ong mammalian placentas and to mechanisms of genomic imprinting.
15 pression, genomic stability, DNA repair, and genomic imprinting.
16 ion is subject to both maternal and paternal genomic imprinting.
17 nonequivalence of parental genomes caused by genomic imprinting.
18 me (PWS) are neurodevelopmental disorders of genomic imprinting.
19 re exceptions, notably in regions subject to genomic imprinting.
20 Approximately 100 genes undergo genomic imprinting.
21 c and genetic features of regions regulating genomic imprinting.
22 future studies of phenotypic plasticity and genomic imprinting.
23 cleolar (sno)RNA species that are subject to genomic imprinting.
24 ble parental allele expression phenomenon is genomic imprinting.
25 he previously reported instances of apparent genomic imprinting.
26 in patterns that mimic those expected under genomic imprinting.
27 native model for investigating mechanisms of genomic imprinting.
28 icking those expected under various modes of genomic imprinting.
29 cal point of the selective forces leading to genomic imprinting.
30 eles and illuminate epigenetic mechanisms of genomic imprinting.
31 olecular bases of Rett syndrome, autism, and genomic imprinting.
32 sophila melanogaster are not attributable to genomic imprinting.
33 for understanding the evolution of mammalian genomic imprinting.
34 use chromosome 7C region, that is subject to genomic imprinting.
35 ests a significant role for YY1 in mammalian genomic imprinting.
36 eins that act in trans to induce or maintain genomic imprinting.
37 expression of alleles at a locus results in genomic imprinting.
38 ng, such as in X-chromosome inactivation and genomic imprinting.
39 e effects of different mutant backgrounds on genomic imprinting.
40 encies in multiple genes that are subject to genomic imprinting.
41 perinatal lethality in C57BL/6J mice due to genomic imprinting.
42 mmetry of expression is breached by allowing genomic imprinting.
43 Expression at this locus is mediated by genomic imprinting.
44 a greater proportion of parameter sets with genomic imprinting.
45 igenetic modifications that are critical for genomic imprinting.
46 exual reproduction through the phenomenon of genomic imprinting.
47 ic variation in the level of expression, and genomic imprinting.
48 f this highly conserved protein in mammalian genomic imprinting.
49 y, phenotypes commonly observed in defective genomic imprinting.
50 sual mode of sex determination that involves genomic imprinting.
51 en syndrome to defective DNA methylation and genomic imprinting.
52 paternal or maternal imprints, which lead to genomic imprinting.
53 ders, and ZFP57, a trans-acting regulator of genomic imprinting.
54 ctive fitness, early zygotic development and genomic imprinting.
55 adaptation rather than the kinship theory of genomic imprinting.
56 for understanding the biochemical aspects of genomic imprinting.
57 resulting from X-chromosome inactivation and genomic imprinting, a large-scale analysis of allelic ge
61 tiple equilibria exist both with and without genomic imprinting, although they occurred in a greater
62 gene regulation, including the emergence of genomic imprinting, an epigenetic regulation leading to
63 ent roles in mammalian brains as a result of genomic imprinting, an epigenetic regulation leading to
66 at MeCP2 plays no role in the maintenance of genomic imprinting and add PEG3 and PEG10 to the list of
70 finger CCCTC-binding factor (CTCF) regulates genomic imprinting and gene expression by acting as a tr
71 as a paradigm for fHC but also relate it to genomic imprinting and homeobox (Hox) gene cluster repre
72 hes, we evaluated influences of X chromosome genomic imprinting and hormone replacement therapy on br
73 rther roles for ZFP57-mediated regulation of genomic imprinting and identifies a novel mechanism for
75 cations -- for example, when one is modeling genomic imprinting and must keep track of the parental o
77 fitness effects can lead to the evolution of genomic imprinting and place recent theoretical advances
79 howed that the Mcts2/H13 locus is subject to genomic imprinting and that alternative polyadenylation
80 s, which should improve our understanding of genomic imprinting and the role of genomic imprinting in
86 romosomes, a well-known mechanism leading to genomic imprinting and X-chromosome inactivation, is wid
87 n has key roles in several processes such as genomic imprinting and X-chromosome inactivation, the fu
88 ally regulated sequences, including sites of genomic imprinting, and at the X-inactivation centre, su
91 f alphaCGRP in adulthood did not result from genomic imprinting, and differences between B6 and cJ mi
93 ce in unilineal and bilineal relatives under genomic imprinting, and some generalized linear function
94 plays an important role in gene expression, genomic imprinting, and suppression of transposable elem
95 activation, transposable element repression, genomic imprinting, and tissue-specific gene expression.
97 Variation in imprinted loci and control of genomic imprinting appear to underlie the hybrid effects
102 analysis suggests that maternal and paternal genomic imprinting are equally rare events in Arabidopsi
106 aternal-offspring coadaptation theories view genomic imprinting as a mechanism to modify the resembla
107 hese findings highlight dosage regulation by genomic imprinting as being critical for maintaining a b
109 dback network between free methyl groups and genomic imprinting at birth.-Tserga, A., Binder, A.
112 dentification of endogenous imprinted genes, genomic imprinting became well-established as an epigene
114 nalyses maternal effects are confounded with genomic imprinting because they can produce the same pat
116 e "conflict hypothesis" for the evolution of genomic imprinting but do not clearly demonstrate common
117 lation in gametes is not entirely related to genomic imprinting but is a strong factor in determining
118 entially involved not only in the origins of genomic imprinting, but also in its maintenance in human
119 r with described roles in X inactivation and genomic imprinting, but Smchd1 is also critically involv
120 as been well characterized as a paradigm for genomic imprinting, but the H19 RNA's biological functio
121 s the dominant evolutionary explanation for "genomic imprinting." But a new study in PLOS Biology pro
122 stigates the potential roles of macroH2A1 in genomic imprinting by lowering the cellular levels of th
124 ave been primarily studied in the context of genomic imprinting, cancer, and cell differentiation, ar
127 oss of UBE3A expression, a gene regulated by genomic imprinting, causes Angelman syndrome (AS), a rar
128 center, and is regulated by a combination of genomic imprinting, cell lineage-dependent erasure of im
130 defective lineage specification and loss of genomic imprinting, compromising normal development.
131 Angelman syndrome gene, UBE3A, is subject to genomic imprinting controlled by mechanisms that are onl
135 evealed an increased incidence of growth and genomic imprinting disorders in children conceived using
137 e predictions of models for the evolution of genomic imprinting (e.g., conflict models), but other ge
138 hromatin modifications, DNA methylation, and genomic imprinting, each of which is altered in cancer c
140 o these mammalian evolutionary developments, genomic imprinting emerged as a monoallelic gene dosage
141 ng of several biological processes including genomic imprinting, epigenetic reprogramming and the est
145 tion imprint, suggesting that the memory for genomic imprinting had been lost or altered in Zfp57-nul
153 ch highlights the role of CpG methylation in genomic imprinting, histone and chromatin modification,
154 t3b are responsible for the establishment of genomic imprinting, how the methylation mark is erased d
162 tion provides insight into the regulation of genomic imprinting in hESCs and the corresponding peri-i
163 A benefit of our and other recent studies of genomic imprinting in hESCs was the identification of im
175 m a useful tool to dissect the regulation of genomic imprinting in normal development and disease.
176 n the tammar wallaby confirm the presence of genomic imprinting in nutrient-regulatory genes in the a
177 mic imprinting while supporting the study of genomic imprinting in placenta for the determination of
179 able that tie the fetal growth trajectory to genomic imprinting in response to environmental stimuli,
180 we interrogated the existence or absence of genomic imprinting in the 12-day-old chicken embryonic b
182 ation, so there may be greater selection for genomic imprinting in the mammary gland than in the shor
183 better understanding of the significance of genomic imprinting in the normal and pathological brain
184 lve CSD, but it is consistent with a form of genomic imprinting in which activation of the female dev
185 leolar (sno) RNA species that are subject to genomic imprinting, including snord115 that negatively r
186 ta demonstrate that epiallelic variation and genomic imprinting intersect to produce novel gene expre
194 ly imprinted in both species, revealing that genomic imprinting is a rapidly evolving phenomenon in p
218 Together these studies provide evidence that genomic imprinting is critical for regulating growth and
224 This indicates that the ability to undergo genomic imprinting is not an inherent property of all me
228 ific; an important trans-acting regulator of genomic imprinting is regulated by this phenomenon; and
232 e of its strict parent-of-origin dependence, genomic imprinting is thought to contribute to the aberr
233 Prader-Willi syndrome (PWS), a disorder of genomic imprinting, is characterized by neonatal hypoton
234 ve distinct viabilities, as might occur with genomic imprinting, it also applies if reciprocal hetero
240 o the general life environment, the study of genomic imprinting may reveal critical information on al
241 parent-of-origin effects, perhaps including genomic imprinting, may play a role in human obesity.
242 for female sexual development and suggest a genomic imprinting mechanism involving an imprinted gene
243 ions driven by specific KRAB-ZFPs, including genomic imprinting, meiotic recombination hotspot choice
244 ion embryos, among other anomalies including genomic imprinting, mitochondrial and cytoplasmic hetero
245 a new, independent line of evidence for the genomic imprinting model of Nasonia sex determination.
247 act of folic acid intake during pregnancy on genomic imprinting of IGF2/H19 and 1-carbon metabolism.
249 cific to embryonic X inactivation as neither genomic imprinting of multiple genes nor imprinted X ina
251 s genre are necessary for the full impact of genomic imprinting on mammalian gene expression and phen
253 ted regions (DMRs) associated primarily with genomic imprinting or DNA sequence variation acting in c
265 verall, the functional connection of Rex1 to genomic imprinting represents another case where newly m
274 hypermethylation; and (ii) for mechanisms of genomic imprinting since point mutations of CTCF binding
275 However, although the kinship theory of genomic imprinting suggests that parent-of-origin-specif
276 type is uncertain due to the consequences of genomic imprinting that in mammalian uniparental tissues
277 response to environmental stimuli, making of genomic imprinting the driving force of the fetal growth
279 f DNA methylation and H3K27me3 in regulating genomic imprinting, the contributions of allele-specific
281 A current model concerning the evolution of genomic imprinting, the parental conflict hypothesis, po
283 neral framework for statistical inference of genomic imprinting underlying allometry scaling in anima
285 f two epigenetic systems--X inactivation and genomic imprinting--using the genes Atp7a and Igf2, resp
286 n insights into these essential processes in genomic imprinting, we examined how ZFP57 maintains geno
290 bject to X chromosome inactivation (XCI) and genomic imprinting, which were not corrected during dire
291 describing the transgenerational meaning of genomic imprinting while supporting the study of genomic
292 ent deluge of data, future investigations of genomic imprinting will require integrating evolutionary
293 findings reveal the remarkable complexity of genomic imprinting, with important implications for unde
294 , computational prediction, and evolution of genomic imprinting would be better addressed by having a
295 a role in diverse biologic processes such as genomic imprinting, X chromosome inactivation, and silen
296 lian development, retrotransposon silencing, genomic imprinting, X-chromosome inactivation, and cance
297 ding of a wide range of phenomena, including genomic imprinting, X-chromosome inactivation, and cis-r
298 g embryonic development, tissue homeostasis, genomic imprinting, X-chromosome inactivation, and germ
299 l cases of monoallelic expression, including genomic imprinting, X-inactivation, and random monoallel
300 ulate gene expression in processes including genomic imprinting, X-inactivation, and transvection.