ライフサイエンスコーパス: genotype and phenotype

1 hizophrenia, there is no direct link between genotype and phenotype.

2 l health care, as a possible marker for LQT1 genotype and phenotype.

3 haromyces as permanent, heritable changes in genotype and phenotype.

4 oded protein will often aid the link between genotype and phenotype.

5 or unravelling complex relationships between genotype and phenotype.

6 of 42 patients and the relationship between genotype and phenotype.

7 vocally demonstrating an association between genotype and phenotype.

8 by studies investigating the interaction of genotype and phenotype.

9 olution and whole-genome sequencing can link genotype and phenotype.

10 ental and physiological mechanisms that link genotype and phenotype.

11 by studies investigating the interaction of genotype and phenotype.

12 e of the genome and the relationship between genotype and phenotype.

13 es networks of interacting molecules between genotype and phenotype.

14 d how to understand the relationship between genotype and phenotype.

15 determine the complex relationships between genotype and phenotype.

16 ptional regulation is a crucial link between genotype and phenotype.

17 erature stress increase correlations between genotype and phenotype.

18 ders and, thus, for the relationship between genotype and phenotype.

19 ey to understanding the relationship between genotype and phenotype.

20 can be viewed at hierarchical levels to link genotype and phenotype.

21 ered systems offer exquisite control of both genotype and phenotype.

22 stablishing a causative relationship between genotype and phenotype.

23 the environment on the relationship between genotype and phenotype.

24 his by creating hybrid rate matrices between genotype and phenotype.

25 g for redundancy and subsequent diversity in genotype and phenotype.

26 subgroups exist that can be defined by their genotype and phenotype.

27 ial animal models have a corresponding human genotype and phenotype.

28 nd in investigating the relationship between genotype and phenotype.

29 or associations between evolutionary rate of genotype and phenotype.

30 new correlations to be drawn between disease genotype and phenotype.

31 d to inflation of false associations between genotype and phenotype.

32 tics aims to understand the relation between genotype and phenotype.

33 ould result in a lack of correlation between genotype and phenotype.

34 These data demonstrate a correlation between genotype and phenotype.

35 well as in facilitating correlations between genotype and phenotype.

36 de and in establishing a correlation between genotype and phenotype.

37 ion volume and risk factors, or between apoE genotype and phenotype.

38 ins according to their BtR-4 gene disruption genotype and phenotype.

39 le to establish a strong association between genotype and phenotype.

40 istical significance of associations between genotype and phenotype.

41 in primary tumors that are heterogeneous in genotype and phenotype.

42 ith, for many, only a loose relation between genotype and phenotype.

43 l studies also evaluate the relation between genotype and phenotype.

44 athways into intermediate components between genotype and phenotype.

45 can be harnessed to span the divide between genotype and phenotype.

46 rovide insight into the relationship between genotype and phenotype.

47 data for exploring the relationship between genotype and phenotype.

48 g meaningful relationships between C. parvum genotype and phenotype.

49 of the potential relationships between human genotype and phenotype.

50 Dahl salt-resistant (R) rats ascertained for genotype and phenotype.

51 reliminary evidence of a correlation between genotype and phenotype.

52 ndence of mutations-is critical for relating genotype and phenotype.

53 there was no significant association between genotype and phenotype.

54 ly cause of the observed disconnects between genotype and phenotype.

55 ical findings to enable correlations between genotype and phenotype.

56 led and assessed for any association between genotype and phenotype.

57 alogue of variants to bridge the gap between genotype and phenotype.

58 chromosome A01 showed co-segregation between genotype and phenotype.

59 t for understanding the relationship between genotype and phenotype.

60 t allows multivariate representation of both genotype and phenotype.

61 approaches to study the relationship between genotype and phenotype.

62 ent methods may miss important links between genotype and phenotype.

63 only recent generations are available to be genotyped and phenotyped.

64 with European ancestry from the database of genotypes and phenotypes.

65 sumptions about the relationship between the genotypes and phenotypes.

66 nate tumours universally regardless of their genotypes and phenotypes.

67 p of hereditary disorders with heterogeneous genotypes and phenotypes.

68 to modify the existing associations between genotypes and phenotypes.

69 GN's community annotation tools for curating genotypes and phenotypes.

70 d with high resolution by correlating strain genotypes and phenotypes.

71 ry serotype M3 strains representing distinct genotypes and phenotypes.

72 omposed of an amalgam of cells with distinct genotypes and phenotypes.

73 rols of European ancestry) from databases of Genotypes and Phenotypes.

74 herited retinal disorders with heterogeneous genotypes and phenotypes.

75 proved clusterings that better differentiate genotypes and phenotypes.

76 used in discovering the association between genotypes and phenotypes.

77 f precise information on the mapping between genotypes and phenotypes.

78 h high-throughput technologies for bacterial genotyping and phenotyping.

79 ingococci were isolated and characterized by genotyping and phenotyping.

80 t to establish a causal relationship between genotype and phenotype?

81 clear link remains to be established between genotype and phenotype.(3,5) In this Review, we summaris

82 ise linear causal relationship between tumor genotype and phenotype, a reminder of logician Carveth R

83 nsive compilations of ecologically important genotypes and phenotypes accrue, predictive abilities fo

84 stage one were gathered from the database of genotypes and phenotypes; additional control individuals

85 Studies of viral genotype and phenotype after virus rebound revealed that

86 Variant genotypes and phenotypes, allelic frequencies in differe

87 ating event, were generated and submitted to genotype and phenotype analyses.

88 step for unraveling the relationship between genotype and phenotype and can yield important insights

89 association between antimicrobial resistance genotype and phenotype and correlated phylogenetic clust

90 ation to preserve the essential link between genotype and phenotype and discuss how cells and biomime

91 f the invasive and metastatic uveal melanoma genotype and phenotype and underscores the plasticity of

92 rspecific hybridization substantially alters genotypes and phenotypes and can give rise to new lineag

93 for Biotechnology Information's Database of Genotypes and Phenotypes and made available via a custom

94 tion for studies of the relationship between genotype and phenotype, and a basis for studies of the p

95 ed pathways, infer the relationships between genotype and phenotype, and explain disease heterogeneit

96 f the gene repertoire, in the way of linking genotype and phenotype, and in the selection approach.

97 osa CF isolate AA2 evolves towards a CF-like genotype and phenotype, and most studied evolutionary ad

98 Cell genotype and phenotype, and nutrient, oxygen, and growth

99 Pathogenic mutations are classified by both genotype and phenotype, and the NUMT sequences permits d

100 orphic encryption that obscures individuals' genotypes and phenotypes, and is suited to quantitative

101 h susceptibility gene, relationships between genotypes and phenotypes, and potential interactions bet

102 volutionary questions, followed by sampling, genotyping, and phenotyping, and ending in analytical me

103 For discovering how genotype and phenotype are linked to each other, it is e

104 continued study of the relationships between genotype and phenotype are necessary to better understan

105 ing datasets of patients that have been both genotyped and phenotyped are the key requisite when aimi

106 Moreover, discordant results between genotypes and phenotypes are a common source of confusio

107 New genotypes and phenotypes are recognized and new therapie

108 selected for adaptive metabolically thrifty genotypes and phenotypes are rendered deleterious throug

109 copy, enabling longitudinal studies of tumor genotype and phenotype as a function of response to chem

110 refully scrutinize the relationships between genotype and phenotype as they pertain to clinical pract

111 Considering the genotype and phenotype as two complex objects, this also

112 ifications, elucidating causal links between genotype and phenotype, as well as the ability to design

113 A high percentage of genotype and phenotype associations (>75%) was observed

114 A lack of genotype and phenotype associations, a potential burden

115 ll reportable findings for the assessment of genotype and phenotype associations, and 137 (11.5%) had

116 as lasso and elastic net in inferring sparse genotype and phenotype associations, in which the number

117 phenotype associations, and 137 (11.5%) had genotype and phenotype associations.

118 o be quantitative and identified population, genotype, and phenotype associations.

119 his approach, making it difficult to connect genotype and phenotype at the level of individual cells.

120 to be able to rigorously characterize their genotypes and phenotypes at the cellular and molecular l

121 s a challenge to detect associations between genotypes and phenotypes because of insufficient sample

122 from their ability to compute a link between genotype and phenotype, but their ability to accurately

123 A new approach was developed to link genotype and phenotype by fusing the target RBP to zinc

124 enes using a novel strategy based on linking genotype and phenotype by in vitro compartmentalization

125 to explain the complex relationship between genotype and phenotype by using network models.

126 association between insulin resistance (IR) genotypes and phenotypes can be modified by obesity-life

127 hin a biofilm population, cells with diverse genotypes and phenotypes coexist, suggesting that distin

128 fluencing haemodynamic traits in large-scale genotyped and phenotyped cohorts where local spatial ave

129 metabolite alterations in cases with various genotypes and phenotypes compared to controls, and we fo

130 Genotype and phenotype correlated between OP and BALF is

131 There was found to be evidence of genotype and phenotype correlation in Wilson disease, wh

132 HD risk factor and suggests that complex DAT genotype and phenotype correlations contribute to differ

133 an-ethnic disease variants, provided initial genotype and phenotype correlations, and established the

134 echanisms of disease and to explore personal genotype and phenotype correlations.

135 In our study, we simulated genotype and phenotype data and then compared the powers

136 ips to phenotype images, providing access to genotype and phenotype data associated with quantitative

137 cognition of the difficulty of accessing raw genotype and phenotype data due to privacy and logistic

138 To determine its significance, we assemble genotype and phenotype data for 21 affected individuals

139 To address this gap, we collected both genotype and phenotype data for 39,696 individuals with

140 or), a program to simulate region/gene-level genotype and phenotype data for complex and Mendelian tr

141 present the unique considerations for using genotype and phenotype data from biobank-linked EHRs for

142 h a focus on what can be gained by analyzing genotype and phenotype data from close relatives.

143 nation frequency, and the ability to collect genotype and phenotype data in community databases.

144 Sharing human genotype and phenotype data is essential to discover oth

145 Including both genotype and phenotype data together with measurements o

146 Genotype and phenotype data were correlated and examined

147 To incorporate both genotype and phenotype data with gene expression, 4 grou

148 tabase driven web-based tool that integrates genotype and phenotype data, association analysis result

149 Combined with more genotype and phenotype data, they will help facilitate m

150 xisting test of selection that requires both genotype and phenotype data-the new test achieves compar

151 ical tools, and by access to vast amounts of genotype and phenotype data.

152 plied to summary data, without access to raw genotype and phenotype data.

153 sentation and features from high dimensional genotype and phenotype data.

154 summary statistics without individual-level genotype and phenotype data.

155 require the availability of individual-level genotype and phenotype data.

156 Ca in cases-controls study from databases of genotype and phenotype (dbGaP), which are in linkage dis

157 The database of Genotypes and Phenotypes (dbGaP) Data Browser was develo

158 The Database of Genotypes and Phenotypes (dbGap) is a National Institute

159 nterface for users with approved Database of Genotypes and Phenotypes (dbGaP) projects to easily retr

160 association studies through the database of Genotypes and Phenotypes (dbGaP).

161 reely available through the NCBI database of Genotypes and Phenotypes (dbGaP).

162 several repositories such as the database of Genotypes and Phenotypes (dbGaP).

163 and Environment project [via the database of Genotypes and Phenotypes (dbGAP)].

164 Each woman's genotype and phenotype determine her ability to adapt in

165 e of etoposide, and the relationship between genotype and phenotype differs by race.

166 A gradient in genotype and phenotype distribution exists across Europe

167 Two routes, genotype- and phenotype-driven, can be used for the reco

168 nges to elucidating the relationship between genotype and phenotype, especially in neopolyploid speci

169 In the gulf between genotype and phenotype exists proteins and, in particula

170 phor for describing the relationship between genotype and phenotype for a population under selection.

171 tunity to establish functional links between genotype and phenotype for complex traits such as type 1

172 elucidate the complex relationships between genotype and phenotype for different forms of CKD, suppo

173 ical foundations to make connections between genotype and phenotype for ecologically important pigmen

174 results demonstrate a robust correlation of genotype and phenotype for GLI3 mutations and strongly s

175 Recognition of the distinct genotype and phenotype for this subset of APAs could fac

176 Over 700 F2 mice were densely genotyped and phenotyped for a panel of 40 body and orga

177 The cohorts were whole-genome genotyped and phenotyped for ARDS.

178 n described, providing a wealth of different genotypes and phenotypes for genetic and other studies.

179 ctural information, as well as corresponding genotypes and phenotypes generated by a highly sensitive

180 tic models (phenotype; genotype; phenotype + genotype; and phenotype + genotype + demographic + envir

181 o obtain gene expression data in addition to genotypes and phenotypes, giving us new opportunities to

182 Understanding genome-wide links between genotype and phenotype has generally been difficult due

183 lasticum varies, and the correlation between genotype and phenotype has not been established.

184 enetic variation in vivo, and changes in Rev genotype and phenotype have been shown to coincide with

185 as well as more precise correlations between genotype and phenotype have facilitated the progress mad

186 nd navigation bar, (ii) expanded support for genotypes and phenotypes, (iii) comprehensive phenotype

187 Comparison between genotype and phenotype in 23 families failed to yield an

188 aim was to determine the association between genotype and phenotype in 681 affected male participants

189 light on the intricate relationship between genotype and phenotype in a wide range of inherited huma

190 precision medicine, bridging the gap between genotype and phenotype in an in vivo setting.

191 ease apart the complex relationships between genotype and phenotype in aneuploidy and segmental aneus

192 ation for exploring the relationship between genotype and phenotype in angiosperms, enhance the utili

193 bles exploration of the relationship between genotype and phenotype in biobank cohorts, such as the U

194 r genes and provides a possible link between genotype and phenotype in cancer.

195 This study provides the first link between genotype and phenotype in choanoflagellates and raises t

196 xperiments have defined correlations between genotype and phenotype in chronic pain diseases and focu

197 comprehensive genome-wide approaches to link genotype and phenotype in model organisms.

198 was identified as Flv by correlation between genotype and phenotype in nine mouse strains.

199 ur understanding of the relationship between genotype and phenotype in plants.

200 or population studies of association between genotype and phenotype in S. cerevisiae.

201 toward developing a more robust link between genotype and phenotype in this complex disorder.

202 vel with kinase domain (KD) mutation status, genotype, and phenotype in 1855 Ph(+) leukemias.

203 approach analyses the relationships between genotypes and phenotypes in terms of differences (change

204 a spectrum of vector species with different genotypes and phenotypes in the context of malaria trans

205 decisions toward resource allocation (e.g., genotyping and phenotyping) in order to maximize predict

206 evidence for adaptation in vivo, in terms of genotype and phenotype including antibiotic resistance.

207 tions involve a complex relationship between genotype and phenotype, including interactions between u

208 The discordance between genotype and phenotype indicates that extrinsic factors

209 reatment algorithms, which are based on both genotype and phenotype information.

210 Bridging genotype and phenotype is a fundamental biomedical chall

211 Understanding the relationship between genotype and phenotype is a major biological question an

212 ple mutational cause, the connection between genotype and phenotype is complex and multidimensional,

213 This inconsistency between genotype and phenotype is illustrated in the malformatio

214 Although the causal relationship between genotype and phenotype is not presently understood, our

215 COL1A1 and COL1A2, the relationship between genotype and phenotype is not yet well understood.

216 Dissecting the relationship between genotype and phenotype is one of the central goals in de

217 Mapping between genotype and phenotype is one of the primary goals of ev

218 The relationship between genotype and phenotype is remarkably close in the animal

219 However, the relationship between genotype and phenotype is very weak.

220 The Database of Genotypes and Phenotypes is a National Institutes of Hea

221 plexities of the relationships between virus genotype and phenotype make such predictions extremely d

222 phenotype establishes a causal link between genotype and phenotype, making possible carrier and popu

223 ergence of artemisinin resistance-associated genotypes and phenotypes (maximum mean change in antibod

224 High-throughput mapping between genotype and phenotype may apply to artificial selection

225 icant associations between fetal heart rate, genotype, and phenotype; mean third trimester prelabor f

226 The National Ophthalmic Disease Genotyping and Phenotyping Network (eyeGENE((R))) was es

227 ase, created The National Ophthalmic Disease Genotyping and Phenotyping Network (eyeGENE).

228 We analyzed the genotype and phenotype of CF patients 40 years and older

229 ur ability to understand the linkage between genotype and phenotype of disease.

230 Here, we report the genotype and phenotype of each affected patient, as well

231 Comparisons of the genotype and phenotype of each virus suggested that VP1/

232 se hepatitis virus (MHV), to investigate the genotype and phenotype of MHV quasispecies selected for

233 ng-sought odorants used to recognize the MHC genotype and phenotype of other individuals.

234 or polyploidy, has important effects on the genotype and phenotype of plants, potentially altering e

235 The genotype and phenotype of the M2-2 deletion mutant were

236 In the present study, both the genotype and phenotype of these mice were characterized,

237 CYP2D6 genotypes and phenotypes of 550 service personnel were d

238 Studies of genotypes and phenotypes of FNH and HCAs have led to the

239 The type III secretion genotypes and phenotypes of isolates cultured from the p

240 Tumor subclasses differ according to the genotypes and phenotypes of malignant cells as well as t

241 Here, we report detailed genotypes and phenotypes of TALEN-edited MECP2 mutant cy

242 y increasing their fitness, and analyzed the genotypes and phenotypes of the evolved cells.

243 Analysis of the genotypes and phenotypes of these mutant genes has revea

244 Genotyping and phenotyping of 186 apple accessions from

245 were tested in the present study by further genotyping and phenotyping of 23 cpb2-positive C. perfri

246 were tested in the present study by further genotyping and phenotyping of 29 cpb2-positive C. perfri

247 Here we describe the systematic generation, genotyping and phenotyping of 711 iPS cell lines derived

248 Comparative genotyping and phenotyping of nearly 12,000 O. biennis i

249 rombocytopenia that were recruited to the UK Genotyping and Phenotyping of Platelets (GAPP) study.

250 We compared genotyping and phenotyping of the four inhibitory KIRs t

251 Recent developments allow unparalleled genotyping and phenotyping of tumours, providing a pleth

252 However, genotype and phenotype often do not correlate due to con

253 n Omnibus, Entrez Probe, GENSAT, Database of Genotype and Phenotype, Online Mendelian Inheritance in

254 XLP but that there is no correlation between genotype and phenotype or outcome.

255 CD4(+) T cells and B cells of more than 100 genotyped and phenotyped patients with inflammatory arth

256 These populations will be genotyped and phenotyped, permitting high-power and high

257 ts (9 LQT1, 9 LQT2, 5 LQT3, and 2 LQT5) with genotype and phenotype positive LQTS underwent ECG imagi

258 opulation-based analytical measurements with genotype and phenotype provides productive insight into

259 at globally affects the relationship between genotype and phenotype, [PSI(+)] expands the conceptual

260 y program that can efficiently generate both genotypes and phenotypes, regardless of pedigree structu

261 Understanding the relation between genotype and phenotype remains a major challenge.

262 Linking genotype and phenotype remains the holy grail of crop bi

263 Genotype and phenotype results were provided to patients

264 tic uniqueness, the many attributes of their genotype and phenotype shared with others, their more di

265 orphism is a strong and stable clustering in genotype and phenotype space.

266 Selective genotyping and phenotyping strategies are used to lower

267 We examine the efficiency of different genotyping and phenotyping strategies in inbred line cro

268 ived from two publicly available database of Genotypes and Phenotypes studies [phs000404.v1.p1 and ph

269 n the Women's Health Initiative Database for Genotypes and Phenotypes Study, our previous genome-wide

270 This disconnect between genotype and phenotype suggests that a local event is ne

271 Advances in genotyping and phenotyping techniques have enabled the a

272 nd unrelated healthy subjects, by definitive genotyping and phenotyping techniques.

273 ement and decline in cost of high-throughput genotyping and phenotyping technologies, genome-wide ass

274 Both genotype and phenotype tests require interpretation, and

275 mplexity of the mapping relationship between genotype and phenotype that is a consequence of epistasi

276 sis of the evolutionary relationship between genotype and phenotype that quantitatively links point m

277 xisting challenges in cardiovascular disease genotyping and phenotyping that can be addressed by the

278 ntegrate the strength of association between genotype and phenotype, the variability in the genetic b

279 Because of its desirable genotype and phenotype, this mutant may have the potenti

280 ional prediction scores, allele frequencies, genotypes and phenotypes) to determine the optimal analy

281 alysing the pooled data comprising bacterial genotype and phenotype together with clinical metadata w

282 Hybrids are heterozygous and segregate for genotype and phenotype upon sexual reproduction.

283 are to directly test the association between genotype and phenotype using a phylogenetic framework.

284 infer networks of causal relationships among genotypes and phenotypes using expression quantitative t

285 A possible relationship between genotype and phenotype (virus replication efficiency) is

286 The connection between genotype and phenotype was assessed by determining the a

287 Interpretation of genotypes and phenotypes was concordant in 57 (85%) of t

288 o be the mechanism leading to the changes in genotype and phenotype we observed.

289 er for Biotechnology Information database of genotypes and phenotypes website.

290 neutropenic episodes were recorded, and MBL genotype and phenotype were determined by heteroduplex a

291 samples exhibiting discrepancies between the genotype and phenotype were found to be due to low red c

292 Although genotype and phenotype were largely concordant for first

293 Thus, the sclerotic (Os/+) or normal (+/+) genotype and phenotype were present in, and transmitted

294 Genotypes and phenotypes were correlated by determining

295 dom mating with N(e) of 50, 100, or 200, SNP genotypes and phenotypes were generated on 200, 500, or

296 Sex-specific associations between genotypes and phenotypes were tested.

297 e in detail the complex relationship between genotypes and phenotypes with both theoretical and pract

298 We tested single-locus associations between genotypes and phenotypes with regression models.

299 (INS) and investigated associations between genotype and phenotype, with special attention to extra-

300 ng understanding of the relationship between genotype and phenotype, with the ability to predict some