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1 carboxamide intermediate 2 at carbon 6 with geranyl diphosphate.
2 e (C(50)) from isopentenyl diphosphate and E-geranyl diphosphate.
3 hosphate and isopentenyl diphosphate to form geranyl diphosphate.
4 ation of both geraniol and (R)-linalool from geranyl diphosphate.
5 for activity and produces only geraniol from geranyl diphosphate.
6 e, Rv1086, adds one isoprene unit to omega,E-geranyl diphosphate.
7 , respectively, as their major products from geranyl diphosphate.
8 ated as a possible C-methyltransferase, with geranyl diphosphate (1) and S-adenosylmethionine gave th
10 e the corresponding chlorinated analogues of geranyl diphosphate (3-ClGPP) and farnesyl diphosphate (
11 nzyme activity level (7-fold), and in planta geranyl diphosphate and geranylgeranyl diphosphate level
12 e overexpressed a bifunctional spruce IDS, a geranyl diphosphate and geranylgeranyl diphosphate synth
15 CotB2, commencing with the substrate geranyl geranyl diphosphate and terminating with the carbocation
16 r isopentenyl diphosphate, 38 micrometer for geranyl diphosphate, and 16 micrometer for neryl diphosp
19 to all known monoterpene cyclases, which use geranyl diphosphate as substrate and invoke a cationic i
20 on in Escherichia coli and enzyme assay with geranyl diphosphate as substrate, subsequent analysis of
21 icate that, contrary to the textbook view of geranyl diphosphate as the "universal" substrate of mono
22 he monoterpene bornyl diphosphate (BPP) from geranyl diphosphate by BPP synthase using state of the a
25 in plants typically proceeds through either geranyl diphosphate (C10) or trans-farnesyl diphosphate
26 noid coupling reactions to give a mixture of geranyl diphosphate (chain elongation), chrysanthemyl di
27 rm yeast peroxisomes into microfactories for geranyl diphosphate-derived compounds, focusing on monot
28 mation of the prenyl diphosphate precursors, geranyl diphosphate, farnesyl diphosphate, and geranylge
29 phosphate synthase 1 (PcIDS1) yields 96% C10-geranyl diphosphate (GDP) and only 4% C15-farnesyl dipho
30 se in that it adds only one isoprene unit to geranyl diphosphate, generating the 15-carbon product (E
31 nd dimethylallyl diphosphate (DMAPP) to form geranyl diphosphate (GPP) and between IPP and GPP to giv
32 es, which are derived from linear precursors geranyl diphosphate (GPP) and lavandulyl diphosphate (LP
33 hosphate (BPP), which is itself derived from geranyl diphosphate (GPP) by the enzyme ( +)-bornyl diph
36 ed with dimethylallyl diphosphate (DMAPP) or geranyl diphosphate (GPP) to give the corresponding chlo
38 is hypothesized to originate from 10-carbon geranyl diphosphate (GPP), 15-carbon farnesyl diphosphat
39 te (IPP), dimethylallyl diphosphate (DMAPP), geranyl diphosphate (GPP), farnesyl diphosphate (FPP), a
40 ere the C(10) product of the first addition, geranyl diphosphate (GPP), is the substrate for the seco
41 wers include three monoterpenes derived from geranyl diphosphate (GPP), myrcene, (E)-beta-ocimene and
42 (Humulus lupulus L.) trichomes, derives from geranyl diphosphate (GPP), the common precursor of monot
45 modifies an acyclic isoprenoid diphosphate, geranyl diphosphate (GPP), to yield a noncanonical acycl
48 th dimethylallyl diphosphate (DMAPP, C5) and geranyl diphosphate (GPP, C10) to give (E,E)-FPP (C15).
49 engineer their isoprene donor specificities (geranyl diphosphate [GPP] versus dimethylallyl diphospha
51 lly synthesized as stable analogs of omega,E-geranyl diphosphate in which the labile diphosphate moie
52 , myrcene and (E)-beta-ocimene, derived from geranyl diphosphate, in addition to a major phenylpropan
53 catalyzed the formation of 18O-geraniol from geranyl diphosphate, indicating that the reaction mechan
54 enchol synthase, plant cyclases that convert geranyl diphosphate into products with closely related b
55 The data from both organisms suggest that geranyl diphosphate is the allylic substrate for two dis
57 the coupled isomerization and cyclization of geranyl diphosphate, is reported at 2.7-A; resolution in
58 for rat farnesyl diphosphate (FPP) synthase (geranyl-diphosphate:isopentenyl-diphosphate geranyltrans
59 s the addition of isopentenyl diphosphate to geranyl diphosphate, neryl diphosphate, omega,E,E-farnes
61 dition of isopentenyl diphosphate to omega,E-geranyl diphosphate or omega,Z-neryl diphosphate yieldin
62 terminal domain catalyzes the cyclization of geranyl diphosphate, orienting and stabilizing multiple
64 r content of some compounds related with the geranyl-diphosphate pathway (neryl and geranyl acetates)
65 t cells overexpressing Rv1086 incubated with geranyl diphosphate showed a 5-fold increase of [(14)C]i
68 erized Lavandula x intermedia cDNAs encoding geranyl diphosphate synthase (LiGPPS), geranylgeranyl di
69 phate synthase (SlDXS), Arabidopsis thaliana geranyl diphosphate synthase 1 (AtGPS) and Mentha x pipe
71 the hybrid possesses characteristics of both geranyl diphosphate synthase and geranylgeranyl diphosph
74 diphosphate synthase, which are homodimers, geranyl diphosphate synthase from Mentha is a heterotetr
75 phosphate pathway were overexpressed, and a geranyl diphosphate synthase from the plant Abies grandi
78 ate synthase 1 (AtGPS) and Mentha x piperita geranyl diphosphate synthase small subunit (MpGPS.SSU) o
80 expression in Escherichia coli of the Mentha geranyl diphosphate synthase small subunit with the phyl
81 l subunits of peppermint (Mentha x piperita) geranyl diphosphate synthase, spearmint (Mentha spicata)
84 sis suggested that the heterodimeric geranyl(geranyl)diphosphate synthase [G(G)PPS] is involved in my
85 ted L. x intermedia CINS (LiCINS), converted geranyl diphosphate (the linear monoterpene precursor) p
86 l diphosphate and isopentenyl diphosphate to geranyl diphosphate, the key precursor of monoterpene bi
87 proceed via an RR-dependent isomerization of geranyl diphosphate to 3S-linalyl diphosphate, as shown
88 terpene cyclase limonene synthase transforms geranyl diphosphate to a monocyclic olefin and constitut
91 en proposed to proceed by the cyclization of geranyl diphosphate to y-terpinene, followed by a series
92 ncapable of converting the natural substrate geranyl diphosphate, via the enzymatically formed tertia
93 ase (GES) activity, generating geraniol from geranyl diphosphate, was shown to be localized exclusive
94 additional product, the regular monoterpene geranyl diphosphate, when incubated with isopentenyl dip
95 e formation of 10 volatile monoterpenes from geranyl diphosphate, with 1,8-cineole predominating.