ライフサイエンスコーパス: germinal vesicle

1 ndant component of the oocyte's nucleus (the germinal vesicle).

2 it is present in the intact oocyte nucleus (germinal vesicle).

3 asm but also localized to the disintegrating germinal vesicle.

4 n results in nuclear F-actin only within the germinal vesicle.

5 eated from a novel MTOC near the base of the germinal vesicle.

6 in the many hundreds of B-snurposomes in the germinal vesicle.

7 ucleoli, whereas anti-SC35 did not enter the germinal vesicle.

8 g factors in the amphibian oocyte nucleus or germinal vesicle.

9 In these oocytes, large openings form in the germinal vesicle adjacent to condensing chromatin, and m

10 This directs the movement of the germinal vesicle and associated gurken mRNA from the pos

11 a comprehensive catalogue of transcripts in germinal vesicle and metaphase II oocytes, and in embryo

12 lysome-bound RNA profiles of bovine oocytes (germinal vesicle and metaphase II stages) and early embr

13 thesized during oogenesis, is present in the germinal vesicle, and is released into the egg cytoplasm

14 By exchanging the germinal vesicle between mouse and pig oocytes, we obtai

15 sphodiesterase (PDE), is thought to initiate germinal vesicle breakdown (GVB) by the inactivation of

16 ryl cAMP (dbcAMP) were stimulated to undergo germinal vesicle breakdown (GVB), while there was no eff

17 mouse oocytes, considered OA-insensitive and germinal vesicle breakdown (GVB)-incompetent, displayed

18 nopus oocytes, resulting in the induction of germinal vesicle breakdown (GVBD) and activation of M-ph

19 n mouse oocytes induced significant delay in germinal vesicle breakdown (GVBD) and failure in extrusi

20 as, we show the Mek activity is required for germinal vesicle breakdown (GVBD) induced by co-expressi

21 SIP inhibited germinal vesicle breakdown (GVBD) induced by expression

22 dc2/cyclin B complex) kinase associated with germinal vesicle breakdown (GVBD) induced by progesteron

23 Although mutant oocytes underwent germinal vesicle breakdown (GVBD) prior to ovulation, th

24 tively active Akt in Xenopus oocytes induced germinal vesicle breakdown (GVBD) to the same extent as

25 The capacity of egg cytoplasm to induce germinal vesicle breakdown (GVBD) was inhibited by cyclo

26 g meiotic progression, leading to defects in germinal vesicle breakdown (GVBD), anaphase-promoting co

27 cation competence in meiosis I shortly after germinal vesicle breakdown (GVBD), but repress replicati

28 rease in intraoocyte levels of cAMP precedes germinal vesicle breakdown (GVBD), the gonadotropin indu

29 he level of F-actin decreased at the time of germinal vesicle breakdown (GVBD), which may account for

30 reases during cell cycle reentry, well after germinal vesicle breakdown (GVBD).

31 (MAPK, ERK) leads to activation of cdc2 and germinal vesicle breakdown (GVBD).

32 Mos fully restored both MAP K activation and germinal vesicle breakdown (GVBD).

33 aTrCP-mediated destruction immediately after germinal vesicle breakdown (GVBD).

34 ys the increase in Cdk1 activity, leading to germinal vesicle breakdown (GVBD).

35 hase-arrested oocytes to mature and complete germinal vesicle breakdown (GVBD).

36 equired for meiotic maturation subsequent to germinal vesicle breakdown (GVBD).

37 y 45% of oocytes expressing FA-Rsk underwent germinal vesicle breakdown (GVBD, the G(2)/M transition)

38 f maturation promoting factor (MPF) triggers germinal vesicle breakdown after the luteinizing hormone

39 gnaling cascades, leading to MPF activation, germinal vesicle breakdown and arrest at metaphase of me

40 ) signals are dispensable for meiosis entry (germinal vesicle breakdown and chromosome condensation),

41 but not the R488L or Y497A variants induces germinal vesicle breakdown and cyclin-dependent kinase a

42 esulted in induction of significant rates of germinal vesicle breakdown and meiotic maturation.

43 in became hyperphosphorylated at the time of germinal vesicle breakdown and remained hyperphosphoryla

44 Ccnb2 (-/-) oocytes underwent delayed germinal vesicle breakdown and showed defects during the

45 sociates with XPR after progesterone-induced germinal vesicle breakdown and that active recombinant M

46 enous XFGFR translation begins just prior to germinal vesicle breakdown and that translation depends

47 ell expansion and resumption of meiosis with germinal vesicle breakdown are major events in oocyte ma

48 SOCE inactivation at germinal vesicle breakdown coincides with an increase in

49 RK2/p42 MAPK, JNK is activated just prior to germinal vesicle breakdown during Xenopus oocyte maturat

50 0(S6K) activation, caused oocytes to undergo germinal vesicle breakdown earlier than control oocytes,

51 Activity increases near the time of germinal vesicle breakdown in progesterone-treated oocyt

52 ver, since transcription is not required for germinal vesicle breakdown in progesterone-treated oocyt

53 mutation (G60A) lacks the ability to induce germinal vesicle breakdown in Xenopus oocytes.

54 Ras to transform NIH 3T3 cells and to induce germinal vesicle breakdown in Xenopus oocytes.

55 4E, were active when tested for induction of germinal vesicle breakdown in Xenopus oocytes.

56 regulatory region to inhibit Xenopus oocyte germinal vesicle breakdown induced by the C-terminal cat

57 Pde3a(-/-) oocytes that underwent germinal vesicle breakdown showed activation of MPF and

58 tor (IP(3)R) sensitivity is initiated at the germinal vesicle breakdown stage of maturation, which co

59 pletely, in a very short time period, at the germinal vesicle breakdown stage of meiosis.

60 ing the activity of v-H-Ras to induce oocyte germinal vesicle breakdown when co-injected.

61 ustain prophase I arrest and readily undergo germinal vesicle breakdown, a marker for reentry into MI

62 oinjected normal Ras protein in induction of germinal vesicle breakdown, although it did not affect t

63 nd many different ways to reversibly inhibit germinal vesicle breakdown, and used these findings to d

64 After oocyte activation and germinal vesicle breakdown, cnRNA65 persists as a cytopl

65 Resumption of meiosis is heralded by germinal vesicle breakdown, condensation of chromosomes,

66 Interestingly, during germinal vesicle breakdown, mouse cPLA2gamma aggregates

67 Following germinal vesicle breakdown, PAR-3 surrounds the condensi

68 or activation occurs later, concomitant with germinal vesicle breakdown, the contraction of the micro

69 By compressing oocytes during the process of germinal vesicle breakdown, the position where the meiot

70 rgizes with progesterone in the induction of germinal vesicle breakdown, the translation of Mos, the

71 ed in the immature oocyte and at least until germinal vesicle breakdown.

72 ared during oocyte maturation at the time of germinal vesicle breakdown.

73 one and show accelerated MAPK activation and germinal vesicle breakdown.

74 ll surface, and is 50% complete 1 hour after germinal vesicle breakdown.

75 ion, 75% of CPEB is degraded coincident with germinal vesicle breakdown.

76 ion and meiotic cell cycle progression after germinal vesicle breakdown.

77 oocytes and found that they underwent normal germinal vesicle breakdown; however, SR-BI KO eggs, whic

78 In spread preparations of germinal vesicle contents, an anti-SLBP1 antibody staine

79 actin formation in the nurse cell nuclei and germinal vesicle during mid-oogenesis.

80 filaments first appeared in association with germinal vesicle (GV) and mitochondrial mass (MM) of ooc

81 Based on germinal vesicle (GV) chromatin patterns, fully grown oo

82 The mouse oocyte nucleus or germinal vesicle (GV) exhibits a unique chromatin config

83 mbranated sperm heads when injected into the germinal vesicle (GV) of amphibian oocytes.

84 within 24 h by injection of nuclei into the germinal vesicle (GV) of growing Xenopus oocytes.

85 l repression and chromatin remodeling in the germinal vesicle (GV) of mammalian oocytes.

86 a redistribution of WAVE1 from the cortex in germinal vesicle (GV) oocytes to cytoplasmic foci in ooc

87 ogenous betaine was present at low levels in germinal vesicle (GV) stage mouse oocytes before ovulati

88 on-like [Ca2+]i oscillations in fully grown, germinal vesicle (GV) stage oocytes and determine if the

89 Immature germinal vesicle (GV) stage oocytes show an aggregation

90 ing proteolysis of cyclins and Cdc25B at the germinal vesicle (GV) stage, APC/C associated with the C

91 At the germinal vesicle (GV) stage, ATRX was found associated w

92 uiescence at dictyate prophase I, termed the germinal vesicle (GV) stage, mammalian oocytes reenter m

93 Cep55 is expressed in mouse oocytes from the germinal vesicle (GV) to metaphase II (MII) stages.

94 Chromatin configuration in the germinal vesicle (GV) undergoes dynamic changes during o

95 In the Xenopus germinal vesicle (GV), most coilin actually resides in t

96 Microinjection into germinal vesicle (GV)-intact oocytes of dsRNA correspond

97 Western blot analysis revealed that germinal vesicle (GV)-stage oocytes cultured in dbcAMP-c

98 A carboxylase (ACC) levels were increased in germinal vesicle (GV)-stage oocytes when compared to non

99 e stable during the transcriptionally silent germinal vesicle (GV)-stage to metaphase II (MII)-stage

100 (pre-mitochondrial clouds) that surround the germinal vesicle (GV).

101 nd speckles in the Xenopus oocyte nucleus or germinal vesicle (GV).

102 MacroH2A is localized to chromatin of germinal vesicles (GV) in both late growth stage (lg-GV)

103 The germinal vesicle has an eccentric position in full grown

104 xnf7 protein is stored in the oocyte nucleus germinal vesicle in a hypophosphorylated state.

105 Here we demonstrate that fully grown germinal vesicle-intact (GVI) mouse oocytes contain mRNA

106 zygous mutant Zp3-/- mice had follicles with germinal-vesicle-intact oocytes but that lacked a zona p

107 The region of oocyte surface closest to the germinal vesicle is the site where the polar bodies norm

108 The nucleus of oocytes (germinal vesicle) is unusually large and its nuclear env

109 from the earliest indication of maturation (germinal vesicle movement) to formation of a distinct pr

110 c and Flag) cDNAs for mZP2 and mZP3 into the germinal vesicle (nucleus) of growing oocytes isolated f

111 Xnf7 is localized to the germinal vesicle (nucleus) of immature oocytes in a hypo

112 We examined the localization of SLBP1 in the germinal vesicle of Xenopus laevis oocytes.

113 In the germinal vesicles of clam oocytes at prophase of meiosis

114 ng and more intense punctate staining in the germinal vesicles of oocytes following treatment with th

115 can be directly reprogrammed by the nucleus (germinal vesicle) of amphibian oocytes to express oct-4

116 Notably, germinal vesicle oocyte and zygote chromatin are globall

117 elevated reactive oxygen species in immature germinal vesicle oocytes, exhibit a significant over-acc

118 an oocyte involves a series of steps whereby germinal-vesicle oocytes (in which the nuclei are intact

119 growth-to-maturation transition begins with germinal vesicle or nuclear envelope breakdown (GVBD) an

120 The oocyte germinal vesicle serves as a microtubule organizing cent

121 ted nuclear staining in mouse oocytes at the germinal vesicle stage and in the pronuclei during ferti

122 ecause ovulated oocytes were arrested at the germinal vesicle stage and, therefore, could not be fert

123 anic osmolyte, during vitrification of mouse germinal vesicle stage oocyte and/or subsequent maturati

124 able of correct chromatin association in the germinal vesicle stage oocyte nuclei.

125 al transcripts, regulates their stability in germinal vesicle stage oocytes, and interacts with other

126 InsP(3) in both mouse metaphase II eggs and germinal vesicle stage oocytes.

127 Mouse oocytes at germinal vesicle stage were prevented from meiosis resum

128 ed by a TRP ion channel in immature oocytes (germinal vesicle stage), matured oocytes (metaphase II e

129 only minor changes in gene expression at the germinal vesicle stage, including more than twofold over

130 In fully-grown wild type oocytes at the germinal vesicle stage, PARP-1 protein associates with n

131 At the germinal vesicle stage, phosphorylated GM130 is observed

132 rown mammalian oocytes maintain a prophase I germinal-vesicle stage arrest in the ovary for extended

133 network of cytoplasmic accumulations in the germinal vesicle-stage oocyte (GV) to a network of disti

134 ntiate mouse pluripotent stem cells to large germinal vesicle-stage oocyte-like cells in the absence

135 ta, we discovered that ribosome occupancy in germinal vesicle-stage oocytes is the predominant determ

136 observing the movement and breakdown of the germinal vesicle, the formation of polar bodies and the

137 ured oocytes begins with the movement of the germinal vesicle to the oocyte cell surface, and is 50%

138 Ionophore A23187, although it caused germinal vesicles to disappear and caused transient phos

139 us oocytes; experimental displacement of the germinal vesicle toward the animal pole resulted in loca

140 antibody also showed pronounced label in the germinal vesicles within 1-2 h.