ライフサイエンスコーパス: global

1 Thus, TMR in human sleep transcends global action by selectively promoting specific memories

2 ese results, we explore two mechanisms: 1) a global-adaptation mechanism where the structural connect

3 ng the impact of elevated CO(2) (eCO(2) ) in global agriculture is important given climate change pro

4 Among all the global alignment tools for RNA 3D structures, STAR3D has

5 gE, IgG(4), and IgG epitope recognition at a global, allergome-wide level during allergen-specific im

6 Here, we present global analyses of viral transcript levels to further un

7 Here we present a global analysis of no-till-induced changes of soil C and

8 mbedding-based link prediction method called global and local integrated diffusion embedding (GLIDE).

9 ifying climate change but it is also driving global and particularly polar greening.

10 R) imaging studies have demonstrated reduced global and regional brain volumes in infants with congen

11 We aimed to estimate the global and regional distribution of HIV-1 recombinant fo

12 lts highlight a remarkable interplay between global and regional properties of brain functional inter

13 bited highly overlapping patterns of reduced global and widely distributed parcel-wise neocortical th

14 cquired long-term disability, resulting in a global annual economic burden.

15 In light of the global antimicrobial-resistance crisis, there is an urge

16 secondary structure, it maintains a compact global architecture primed for SUMO interaction.

17 Here, we examined the global AS changes in tomato leaves infected with Phytoph

18 for competency assessment tool and 4.74 for global assessment score whereas laparoscopic rate increa

19 In light of our global assessment, we establish a framework for improvin

20 storage associated with periods of decreased global atmospheric CO(2) concentration during the LGM, c

21 As global availability of rotavirus vaccines increases, rec

22 sampling, this combined dataset represents a global baseline available for interrogation by future mi

23 l habitat is the major driver of the current global biodiversity crisis.

24 on Biological Diversity's (CBD's) post-2020 global biodiversity framework and targets will be develo

25 ting that a potentially catastrophic loss of global biodiversity is on the horizon(1-3).

26 Global biodiversity is undergoing rapid declines, driven

27 with impacts ranging from host evolution to global biogeochemical cycles(1,2).

28 lands are important ecosystems in modulating global biogeochemical cycles, yet their biological commu

29 lobal RNFLT and 0.75 (95% CI: 0.65-0.85) for global BMO-MRW (p=0.006).

30 his approach suboptimal for treatment of the global brain lesions present in most human neurogenetic

31 Global brain redistribution of contrast agent was hetero

32 disposition for MS is associated with higher global brain WM FA at an early age in the general popula

33 d relatives, and is the leading cause of the global burden from skin disease.

34 A substantial global burden of carotid atherosclerosis exists.

35 ART use was summarized within Global Burden of Disease (GBD) super-regions, with adjus

36 Using data from the Global Burden of Disease Study 2017 (GBD 2017), this stu

37 stainable Development Goals and the shifting global burden of disease, this systematic review analyse

38 We used results from the Global Burden of Diseases, Injuries, and Risk Factors St

39 major cause of health loss, but data for the global burden of sepsis are limited.

40 II cells (64% of total) generated rhythmic, global Ca(2+) transients at the SW frequency that were s

41 fection underlies a significant share of the global cancer burden.

42 crobial groups that play a major role in the global carbon cycle.

43 with potentially important consequences for global carbon cycling.

44 have great potential to help achieve average global CDR goals of 0.5 to 2 gigatonnes of carbon dioxid

45 med to quantify the impact of hyperoxia upon global cerebral perfusion (gCBF), cognitive performance

46 h is 50 +/- 40% of the estimated increase in global CFC-11 emissions and is consistent with the emiss

47 ibing and thus a novel route to tackling the global challenge of AMR.

48 ARS coronavirus 2 (SARS-CoV-2) pandemic is a global challenge, which the scientific community has tac

49 in the testing phase of the 2019 CPM-RadPath global challenge.

50 UK Research and Innovation Global Challenges Research Fund: Research for Health in

51 predict and mitigate the impacts of ongoing global change across the daunting scope of diversity in

52 ngs highlight that two of the most pervasive global change drivers operate via different pathways whe

53 challenging to conduct ecologically relevant global change experiments over the long times commensura

54 at an unprecedented rate due to a variety of global change factors (GCFs).

55 ion, thereby improving projections of future global change impacts.

56 ARP-1/PARP-2-deficiency host-mice revealed a global change in immunological profile and impaired recr

57 ining how altered signaling conditions under global change will impact the evolutionary trajectory of

58 In an era of rapid global change, our ability to understand and predict Ear

59 d can be applied to improve understanding of global change.

60 cation" of northern peatlands in response to global change.

61 bust interspecific trait relationships under global changes, and call for linking within-species resp

62 he uncertainty of particle dry deposition in global chemical transport models.

63 with implications of a positive feedback to global climate and emphasize the close linkage between s

64 Global climate and land use change are causing woody pla

65 rucial importance, especially in the face of global climate change.

66 safe strategy for geoengineering to mitigate global climate change.

67 The changing global climate is having profound effects on coastal mar

68 e El Nino-Southern Oscillation (ENSO) shapes global climate patterns yet its sensitivity to external

69 al Ocean Modeling System (ROMS) to downscale global climate predictions across all Representative Con

70 r the role it can play in stabilizing future global climate.

71 s oxide (N(2)O) plays a critical role in the global climate.

72 stating direct impacts, is expected to cause global climatic perturbations through injections of soot

73 Here, we apply a global coevolution method, statistical coupling analysis

74 community has tackled by mounting extensive global collaborations, combining expertise in diverse ar

75 effect of future research investment through global collaborative efforts and partnerships.

76 9 clinical isolates from Africa deposited in global collections as B. dermatitidis; for 5, we sequenc

77 ncentrations increase by 62% and enhance the global combined anthropogenic and natural aerosol indire

78 avert the loss of transboundary species, the global community must be prepared to invest in some regi

79 visual cortex that may enable both local and global computations.

80 sham rTMS elicited (1) an increase in dlPFC global connectivity, (2) induction of negative dlPFC-amy

81 Global conservation targets to reverse biodiversity decl

82 a multicenter setting as part of an emerging global consortium (MINICOR [Multi-Modal International Ca

83 Mercury (Hg), a global contaminant, is emitted mainly in its elemental f

84 ns) were also of high importance in specific global contexts (e.g. for individual taxonomic groups or

85 Myr lag between the delta(13)C excursion and global cooling.

86 y manipulated the local excitability and the global coupling in the virtual human epileptic patient b

87 This change implies a need to improve global coverage through routine immunization with inacti

88 s are urgently needed to address the looming global crisis of antibiotic resistance.

89 suggested that Wnt gradients could provide a global cue that coordinates local PCP with tissue axes.

90 ferases have been studied, the impact of the global cytosine-5 methylome on development, homeostasis

91 Global data fitting was achieved by including experiment

92 This global data repository is used by millions of scientists

93 de-methylation, become de-methylated during global de-methylation, and then become re-methylated.

94 phase have high methylation levels prior to global de-methylation, become de-methylated during globa

95 Surprisingly, global deletion of either, or both, isoform(s) was witho

96 Global deletion of Kir6.1 or SUR2 subunits results in se

97 Global demand for phosphorus (P) requires new agronomic

98 rs are not sufficiently effective to counter global demographic changes.

99 ed by molecular interaction fields (MIFs), a global descriptor class that typically has the highest d

100 wing to the lack of an analytical method for global detection of protein targets of OPs.

101 These individuals presented with hypotonia, global developmental delay, epileptic encephalopathy, an

102 While we found no evidence of global differences in GI between domestic and wild canid

103 on frontal areas of the brain, as opposed to global differences.

104 Global dispersal and increasing frequency of the SARS-Co

105 e spinosaurid clade(15,16), which had a near-global distribution and a stratigraphic range of more th

106 lution of Dppa3 facilitated the emergence of global DNA demethylation in mammals.

107 ded in the final PICU core outcome set: four Global Domains (Cognitive, Emotional, Physical, and Over

108 refore be a promising approach to counteract global donor shortage.

109 employed computational approaches to deduce global dynamics of thin filament components by energy la

110 Plants are foundational for global ecological and economic systems, but most plant p

111 e results have wide-ranging implications for global ecology and for anticipating changes in host use

112 inally, the influence of the downturn in the global economy, the impact of living in quarters among f

113 Group differences in global efficiency and functional connectivity among 12 r

114 ically provide a substantial fraction of the global electrical demand.

115 GHG metric, time horizon, climate threshold, global emissions budget calculation method, and effort-s

116 donesia or 0.44 and 0.74% (95% CI) of annual global emissions.

117 ization and local adaptation of organisms to global environmental change.

118 This article synthesizes the available global evidence on the drivers of national declines in s

119 Thus, the recent evolution and global expansion of A. aegypti promoted arbovirus emerge

120 These changes are validated by targeted and global experimental analysis.

121 ing satellite observations, we show that the global extent of river ice is declining, and we project

122 Global financial crises have led to the understanding th

123 d results to be the current best estimate of global fire effects on ecosystems.

124 tic resonance imaging to evaluate changes in global functional connectivity patterns in 15 patients w

125 ing methods can forecast the occurrence of a global gap or learn effective individualized interventio

126 echanism by which satellite repeats regulate global gene expression in trans via piRNA-mediated gene

127 Here, we found that global genetic ablation of EHD2 in mice leads to increas

128 A global goal of no net loss of natural ecosystems or bett

129 ults have general implications for governing global good or bad commons.

130 Nitrogenous fertilizers have nearly doubled global grain yields, but have also increased losses of r

131 ed by China made a great contribution to the global "greening up." These programs have received world

132 -cause mortality, adjusted for Meta-Analysis Global Group in Chronic Heart Failure score, genotype, l

133 g and may not require cold chain storage for global health and developed world long-acting drug deliv

134 The COVID-19 pandemic represents a massive global health crisis.

135 g discovery of new antibiotics has created a global health crisis.

136 d-transmitted viruses represent a widespread global health problem, with limited treatment options cu

137 ial infarction (STEMI) remains a significant global health problem.

138 Joint Global Health Trials (Medical Research Council, Departme

139 We searched for studies using EMBASE, Global Health, and MEDLINE.

140 aceutical drugs are an important part of the global healthcare system, with some estimates suggesting

141 Herein, we have generated the global histone mark based epigenomic and transcriptomic

142 t the UNAIDS 90-90-90 targets to monitor the global HIV response, highlighting a need to address the

143 5) mortality cost reduction targets within a global human-earth system model with US state-level ener

144 PC-like WM displayed marked global hypomethylation and selective overexpression of h

145 in the marine benthic delta(18)O record for global ice volume and deep-sea temperature variations.

146 pliance and can hinder the implementation of global immunization campaigns.

147 We propose that a Global Immunological Observatory and associated developm

148 Carla (CVR) and Elina (EIZ) established Global ImmunoTalks in April this year; Hongbo (HC) helpe

149 s of herd immunity and on projections of the global impact of SARS-CoV-2 on the human population, and

150 We aimed to assess global implementation based on analysis of multiple geop

151 onserved in proteobacteria, highlighting its global importance.

152 pt levels, however, upon differentiation the global increase in 5hmC content showed an overall positi

153 The steel sector emits 25% of global industrial greenhouse gases, and the U.S. is the

154 A entry channel of the ribosome and leads to global inhibition of mRNA translation upon infection.

155 s an ecologically and economically important global insect species that is continuously exposed to en

156 Global insights into cellular organization and genome fu

157 Regrettably, the global insurgence of isolates resistant to the triazoles

158 mechanism for cortical computations used for global integration of stimulus features.

159 er percutaneous coronary intervention in the GLOBAL LEADERS study.

160 eages of domestic sheep and resolved, at the global level, their paternal origins and differentiation

161 with chromatin and can substantially reduce global levels of H3 acetylation, but how SIRT6 is able t

162 Informed by both global literature and an extensive stakeholder consultat

163 Increases in global longitudinal and circumferential strains and decl

164 Loss of Dnmt3a causes global loss of mCH and a subset of mCG sites resulting i

165 In the context of global malaria elimination efforts, special attention is

166 2015), we investigated capacity-building in global marine natural product discovery.

167 e considered in future investigations of the global marine Si cycle.

168 The two dominant drivers of the global mean sea level (GMSL) variability at interannual

169 0 +/- 0.08 days per 1- degrees C increase in global mean surface air temperature.

170 of climate change is the relentless rise in global mean surface temperature, which is linked closely

171 poral dynamics of climate en route to stable global mean temperature at 1.5 and 2 degrees C above pre

172 angle density (p value = 1.89 x 10(-6)), and global measure of AD pathology (p value = 9.59 x 10(-7))

173 The global median PFP was 15.0% (range 6.6-20.5), conservati

174 Global metabolic changes were driven by both N speciatio

175 Here, we performed global metabolite screening with metabolite set enrichme

176 Herein, we compared the global metabolome of 231 plasma and 97 fecal samples fro

177 14-18), they are unaccounted for in existing global MHW analyses.

178 ining local sensing of morphogen levels with global modulation of gradient spread.

179 e (IHD) and stroke, are the leading cause of global mortality and a major contributor to disability.

180 veral recent studies suggest they may signal global motion.

181 The global movement of pathogens is altering populations and

182 ow that strategically expanding the existing global MPA network to protect an additional 5% of the oc

183 Staphylococcus aureus ST45 is a major global MRSA lineage with huge strain diversity and a hig

184 Chirality codes, global, multivariate descriptors, are then introduced fo

185 vated temperatures have a profound impact on global N cycling processes with implications of a positi

186 amining macrostructural change characterises global neuronal damage, investigating microstructural al

187 These experiments provide evidence that global ocean change can affect the resilience of corals

188 ons indicate increasing deoxygenation in the global oceans and an elevated frequency and intensity of

189 parent study baseline with treatment in the global OLE (APOLLO-patisiran mean change -4.0, 95 % CI -

190 ses and NFkappaB signaling was unaffected by global or HDAC3/6-selective HDACi, and new protein synth

191 ts with day 2 AUC <=515 experienced the best global outcomes (no TF and no AKI).

192 or quantifying both agent-level features and global pattern attributes on a large scale.

193 artery disease, ischemic episodes lead to a global pattern of cardiomyocyte remodeling and dediffere

194 vations provide evidence that in addition to global patterns, frequency-specific inter-hemispheric as

195 We adopted a global perspective in examining the impact of the Syrian

196 has however been seen as challenging from a global perspective.

197 pink bollworm (Pectinophora gossypiella), a global pest of cotton.

198 iosphere models would improve predictions of global photosynthesis.

199 aling current cereal production to a growing global population will be a challenge.

200 e continues to rise, affecting 6%-13% of the global population.

201 nstructed from 14,891 genomes across diverse global populations (54% non-European) in gnomAD.

202 We created a global prediction map of groundwater arsenic exceeding 1

203 Developing a cure for HIV is a global priority.

204 imuli were presented upside-down, disrupting global processing (Experiment 4).

205 commercial plastics production in the 1940s, global production has rapidly accelerated, doubling appr

206 ion by micronutrients and macronutrients and global production is maximized.

207 A global profile of mitochondrial salvage and cell surviva

208 human karyopherin RanBP5 and investigate its global propensity to interact with influenza A virus pol

209 Global protein surface comparison (GPSC) studies have be

210 While ribosome biogenesis and global protein synthesis were unaffected by nsun-1 deple

211 halting translation initiation and reducing global protein synthesis.

212 Global proteomics shows that the spiked CAII is the only

213 The COVID19 epidemic has spurred a global public health crisis.

214 ng and sexual exploitation in particular are global public health issues with widespread, lasting imp

215 Coronavirus disease 2019 (COVID-19) is a global public health problem that has already caused mor

216 virus 2 (SARS-CoV-2) pandemic has devastated global public health systems and economies, with over 52

217 (PM(2.5)) is a major environmental threat to global public health.

218 ot bound by transcription factors during the global re-methylation phase have high methylation levels

219 We present a compilation of global records of anthropogenic atmospheric lead (Pb) sp

220 Global reductions in TBV statistically mediated the obse

221 ficant associations near genes involved with global regulation of gene expression (SATB1) and the est

222 stress-responsive behavior, functioning as a global regulator of organismal responses to stress.

223 tive stress, bacteria utilize iron-dependent global regulators to sense the iron status of the cell a

224 The emergence of SARS-CoV-2 has driven a global research effort to identify medical countermeasur

225 on on RHD in 2018 now mandates a coordinated global response.

226 er molecule signaling and integrate specific global responses against opportunistic bacteria to comba

227 one in the dorsal raphe nucleus, that track global reward state as well as specific outcome events.

228 trace elements (e.g., Al, Fe, Ti) far exceed global riverine and open ocean mean values and highlight

229 They also support the view that global RNA structure significantly modulates protein-RNA

230 Despite excitement around ProQ as a novel global RNA-binding protein, and its potential to serve a

231 Rates of change for global RNFL thickness were obtained using linear mixed m

232 ROC curves were 0.89 (95% CI: 0.84-0.95) for global RNFLT and 0.75 (95% CI: 0.65-0.85) for global BMO

233 Despite the global scale-up of antiretroviral therapy (ART), incarce

234 ation on arbitrarily-sized inputs, including global scale.

235 and quantifying protein phosphorylation on a global scale.

236 afeguarding human health and ecosystems on a global scale.

237 cal hydrologic response, its implications on global-scale climate remains elusive in current ESMs.

238 nk ratios where the model ocean is driven to global-scale colimitation by micronutrients and macronut

239 Here, we provide a global-scale meta-analysis to quantify how changes in th

240 Using these predictive models, we provide a global-scale quantitative and gridded dataset characteri

241 get cell activity through activity-dependent global scaling have been observed only within central ci

242 Activity-dependent global scaling therefore operates on both the presynapti

243 However, global sea-level change as a result of mass loss from ic

244 first study that provides an overview of the global seasonality of sCoVs.

245 vision, including ffCNNs, can explain human global shape processing.

246 Our results suggest that a global shift of the dynamic working point of the brain m

247 al MRI (fMRI) studies have revealed that the global signal (GS) exhibits a nonuniform spatial distrib

248 e, and biogeochemical processes; however, no global snow drought assessments currently exist.

249 Biomass burning is a significant global source of atmospheric particles and a highly vari

250 l forest restoration opportunity land in the Global South, including 12% of the total population in l

251 MH count was associated with global (Spearman rho = 0.27; P = .004) and frontal (rho

252 The rapid global spread of COVID-19 represents perhaps the most si

253 Following an unprecedented global spread(3), the World Health Organization declared

254 stable than spliced transcripts, we found a global stabilization of spliced mRNAs upon T cell activa

255 cal tools necessary to achieve an end to the global STIs epidemic.

256 egardless of the strategy, the complexity of global supply chains will magnify losses beyond the dire

257 Using global supply data and 1,879 life tables from 103 countr

258 -Chem chemical transport model, we find that global surface accumulation-mode number concentrations i

259 model of Trichodesmium growth onto inferred global surface ocean fields of pCO(2) , temperature, lig

260 ear timescale) spectral peak that appears in global surface temperature observations appears to refle

261 As democracy's global tailwinds shift to headwinds, scholars have an op

262 (rho = 0.27; P = .005) amyloid beta load and global tau load (rho = 0.31; P = .001).

263 ins pose a serious threat to controlling the global TB epidemic.

264 op in stratospheric ozone, possibly due to a global temperature rise.

265 The rapid increase of global temperatures highlights the need for a clear asse

266 nterval of sustained global warmth with mean global temperatures markedly higher (by ~2-3 degrees C)

267 lied to select the model best predicting the global test-retest variability from 3 categories of feat

268 c resistant pathogenic bacteria has become a global threat, which besides the development of new drug

269 outcome measure of tic severity was the Yale Global Tic Severity Scale administered by an independent

270 We present a global time series of street-network sprawl-that is, spr

271 We find the global total amount of urban land could increase by a fa

272 We found at least 28% of the global total remaining extent of LPE was affected in Flo

273 uld obligate H2A.Z turnover, we propose that global transcription at yeast promoters is responsible f

274 Global transcriptome analysis and cell wall metabolite m

275 Cyclosporine led to a more pronounced global transcriptome reversion and normalized T(H)17 cel

276 sh a robust method for the identification of global transcriptomic changes in rare metastatic cells d

277 of SARS-CoV-2 is associated with the ease of global travel, and societal dynamics, immunologic naivet

278 The new Global Tuberculosis Network (GTN) aims to conduct resear

279 trategy, our DeltaSILAC profiling revealed a global, unexpected delaying effect of many phosphosites

280 iling of fasting serum was performed using a global, untargeted approach.

281 ronary artery bypass grafting-related GUSTO (Global Use of Strategies to Open Occluded Coronary Arter

282 ng a pragmatic metric of diagnostic yield or global utility of a diagnostic test.

283 Capturing these patterns in global vegetation models requires better mechanistic rep

284 Our results provide a global view of the effects of the loss of ribosome recyc

285 Our work provides the first global view of the phase-separated proteome and suggests

286 nal neural networks were trained to estimate global visual field indices derived from automated Humph

287 und that the extent of vertical asymmetry in global visual processing in human subjects (n = 10) was

288 ation models, particularly in the context of global warming and increasing frequency of droughts.

289 records were used to assess the influence of global warming and regional eutrophication, respectively

290 analysis and applying different GHG metrics (global warming and temperature potentials) and time hori

291 drogen and carbon monoxide mixture) from two global warming gases of carbon dioxide and methane via d

292 Methane (CH(4)), a potent gas with a global warming potential 86-125x that of carbon dioxide

293 gen availability, and body size predict that global warming will limit the aerobic scope of aquatic e

294 Soil degradation due to global warming, water scarcity and diminishing natural r

295 Antarctic Ice Sheet for different amounts of global warming.

296 s the most recent past interval of sustained global warmth with mean global temperatures markedly hig

297 Snow plays a fundamental role in global water resources, climate, and biogeochemical proc

298 roups of samples being compared had distinct global within-group variability.

299 The global yield of the process (cuticle-to-chitosan) was 31

300 metabolic parameters of skeletal muscle from global Zip14 knockout (KO) and wild-type mice (WT).