ライフサイエンスコーパス: glomerulosa

1 ells and maintain the properties of the zona glomerulosa.

2 tional role of genes upregulated in the zona glomerulosa.

3 alcium channel (CaV3.2) expressed in adrenal glomerulosa.

4 osterone-secreting cells of the adrenal zona glomerulosa.

5 production and cell proliferation in adrenal glomerulosa.

6 11 mutations were found in hyperplastic zona glomerulosa adjacent to double-mutant APAs.

7 s, HSD3B2 is expressed at high levels in the glomerulosa and fasciculata, where these steroids are pr

8 inhibits AT(1) binding in adrenal gland zona glomerulosa and kidney glomeruli.

9 rs (AT(1)Rs), present in adrenocortical zona glomerulosa (AZG) cell membranes.

10 uced and secreted by the adrenocortical zona glomerulosa (AZG) cells after angiotensin II (AngII) act

11 to induce beta-catenin signaling and imprint glomerulosa cell fate.

12 es on aldosterone generation in a human zona glomerulosa cell line, H295R.

13 PC5 in the human adrenocortical (HAC15) zona glomerulosa cell line.

14 Zona glomerulosa cells (ZG) of the adrenal gland constantly i

15 companied by marked increase in adrenal zona glomerulosa cells and adrenal P450aldo mRNA.

16 Ex vivo studies in rat adrenal glomerulosa cells confirmed that lipophilic statins acut

17 Here, we show zona glomerulosa cells in the adult adrenal cortex organize i

18 ifferentiation of beta-catenin-positive zona glomerulosa cells into fasciculata cells and sensitises

19 In zona glomerulosa cells of the adrenal gland, angiotensin II-i

20 ce and cell depolarization, which in adrenal glomerulosa cells produces calcium (Ca(2+)) entry, the s

21 aldosterone production in the adrenocortical glomerulosa cells requires induction of the steroidogeni

22 esses as aldosterone production from adrenal glomerulosa cells to boosting pain signals in nociceptor

23 rone synthesis that acts directly on adrenal glomerulosa cells to increase CYP11B2 expression and enh

24 g of angiotensin II to its receptors in zona glomerulosa cells was demonstrated.

25 e important in aldosterone producing adrenal glomerulosa cells where channel dysregulation would lead

26 In adrenal glomerulosa cells, angiotensin II (Ang II) evokes repeti

27 s and intracellular Ca2+ signaling in bovine glomerulosa cells, in which Ca2+ oscillation frequency w

28 rone production and proliferation of adrenal glomerulosa cells.

29 produced modulation observed in adrenal zona glomerulosa cells.

30 cell-attached patches from rat adrenal zona glomerulosa cells.

31 signal for aldosterone production in adrenal glomerulosa cells.

32 acellular calcium concentrations in the zona glomerulosa compared to controls, but the frequency of c

33 re at least five times overexpressed in zona glomerulosa compared with zona fasciculata.

34 ated with a pattern of decreased normal zona glomerulosa CYP11B2 expression and increased aldosterone

35 adenomas, composed of cells resembling zona glomerulosa, have mutations in genes ATP1A1 and CACNA1D.

36 and cells from most of the adult human zona glomerulosa is the likely driver of the mutational succe

37 We performed exome sequencing of ten zona glomerulosa-like APAs and identified nine with somatic m

38 uption of this signaling complex in the zona glomerulosa may provide a new therapeutic approach to li

39 e of the most highly expressed genes in zona glomerulosa of the human adrenal gland.

40 s in the widths of the zonae reticularis and glomerulosa (p < 0.001).

41 One of the most zona glomerulosa-selective genes was ANO4, a member of the an

42 situ and in cells of the native adrenal zona glomerulosa stimulated by Ang II in vivo.

43 ANO4 was 19.9 times higher in zona glomerulosa than in zona fasciculata (p=6.6 x 10(-24)).

44 studying the role of rosettes in adult zona glomerulosa tissue maintenance and function.

45 and whether the adenomas originate from zona glomerulosa, we carried out a microarray analysis compar

46 for production of aldosterone by outer zona glomerulosa (ZG) and glucocorticoids by inner zona fasci

47 ers that develop postnatally, the outer zona glomerulosa (zG) and the inner zona fasciculata (zF).

48 Aldosterone-producing zona glomerulosa (zG) cells of the adrenal gland arrange in d

49 in determining the activation state of zona glomerulosa (zG) cells.

50 one, and progesterone in bovine adrenal zona glomerulosa (ZG) cells.

51 Human adrenal zona glomerulosa (ZG) expression of GJA1 (the main GJ protein

52 duction of aldosterone from the adrenal zona glomerulosa (ZG) is also the most frequent cause of seco

53 aldosterone is produced in the adrenal zona glomerulosa (ZG) under the control of the renin-angioten

54 with conventional adrenocortical zones [zona glomerulosa (ZG), zona fasciculata, and zona reticularis

55 Zona glomerulosa (ZG)-like APAs frequently have mutations of

56 ce of the aldosterone-producing adrenal zona glomerulosa (zG).

57 ay analysis comparing transcriptomes of zona glomerulosa, zona fasciculata, and tumour in human adren

58 mbe, UK), we compared transcriptomes of zona glomerulosa, zona fasciculata, and tumour obtained by la