ライフサイエンスコーパス: glucuronic

1 n to grow with N-acetylglucosamine but not d-glucuronic acid (both components of HA) as a sole carbon

2 ol g(-1)), whereas binding of the competitor glucuronic acid (GA) and other monosaccharides was consi

3 suitable protected thioaldoses derived from glucuronic acid (GlcA) and galactose (Gal).

4 formation occurs by the copolymerization of glucuronic acid (GlcA) and N-acetylglucosamine (GlcNAc)

5 lcNAc) or N-sulfated glucosamine (GlcNS) and glucuronic acid (GlcA) as the primary sites and the link

6 uishing the epimers iduronic acid (IdoA) and glucuronic acid (GlcA) has been a long-standing challeng

7 corporation of radioactive glucose (Glc) and glucuronic acid (GlcA) into lipid-linked disaccharides i

8 ore-shell particles specifically recognizing glucuronic acid (GlcA) or N-acetylneuraminic acid (NANA)

9 glycan decorations that include a conserved glucuronic acid (GlcA) residue and various additional su

10 ries a pentose linked 1-2 to the alpha-1,2-d-glucuronic acid (GlcA) side chains on the beta-1,4-Xyl b

11 ta-glucuronidase (GUS) enzymes that liberate glucuronic acid (GlcA) sugars from small-molecule conjug

12 the 2-OH position of iduronic acid (IdoA) or glucuronic acid (GlcA) within HS.

13 MIPs were prepared with the templates D-glucuronic acid (GlcA), a substructure of hyaluronan, an

14 The distribution of 13C in the Man, Xyl, glucuronic acid (GlcA), and O-acetyl constituents of nat

15 merase (Hsepi) catalyzes C5-epimerization of glucuronic acid (GlcA), converting it to iduronic acid (

16 yzes C5-epimerization of the HS component, d-glucuronic acid (GlcA), into l-iduronic acid (IdoA), whi

17 residues substituted with alpha(1,2)-linked glucuronic acid (GlcA).

18 Glucuronic acid (GlcAp) and/or methylglucuronic acid (Me

19 is a membrane-bound enzyme that utilizes UDP-glucuronic acid (GlcUA) and UDP-GlcNAc to synthesize HA.

20 at transfer N-acetylglucosamine (GlcNAc) and glucuronic acid (GlcUA) in alternative positions in the

21 sed of alternating beta-1,3-Glc and beta-1,4-glucuronic acid (GlcUA) linkages.

22 atalyzes sugar transfer from UDP-Glc and UDP-glucuronic acid (GlcUA) to a polymer with the repeating

23 yltransferase that catalyzes the transfer of glucuronic acid (GlcUA) to the common growing linker reg

24 s comprising 3-sulfated rhamnose linked to d-glucuronic acid (GlcUA), l-iduronic acid (IdoUA), or d-x

25 PmHAS possesses both GlcNAc-transferase and glucuronic acid (GlcUA)-transferase activities.

26 nd without depletion of the HA precursor UDP-glucuronic acid (GlcUA).

27 -ribofuranose and 3-O-[(R)-1-carboxyethyl]-D-glucuronic acid (nosturonic acid) pendant groups.

28 highly sulfated polysaccharide consisting of glucuronic acid (or iduronic acid) linked to glucosamine

29 ctivity against hyaluronan (HA), poly-beta-d-glucuronic acid (poly-GlcUA), and poly-beta-d-mannuronic

30 ) to the key metabolic precursor UDP-alpha-d-glucuronic acid (UDP-GlcA) and display specificity for U

31 e authentic sugar nucleotide precursors, UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylglucosamine (

32 together with UDP-xylose is formed from UDP-glucuronic acid (UDP-GlcA) by UDP-Api synthase (UAS).

33 The biosynthesis of UDP-Xyl from UDP-glucuronic acid (UDP-GlcA) is irreversibly catalyzed by

34 UDP-glucuronic acid (UDP-GlcA) is the precursor of many plan

35 ing (1) the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcA) to the UDP-4' '-ketopentose [

36 ) catalyzes the epimerization of UDP-alpha-D-glucuronic acid (UDP-GlcA) to UDP-alpha-D-galacturonic a

37 is synthesized by the decarboxylation of UDP-glucuronic acid (UDP-GlcA).

38 nverts UDP-2-acetamido-3-amino-2,3-dideoxy-d-glucuronic acid (UDP-GlcNAc3NA) to UDP-2,3-diacetamido-2

39 NAc3NA) to UDP-2,3-diacetamido-2,3-dideoxy-d-glucuronic acid (UDP-GlcNAc3NAcA).

40 ed nucleotide sugars UDP-2-acetamido-2-deoxy-glucuronic acid (UDP-GlcNAcA) and UDP-2-acetamido-2-deox

41 te (Glc-6-P) --> Glc-1-P --> UDP-Glc --> UDP-glucuronic acid (UDP-GlcUA) --> (GlcUA-Glc)(n).

42 accharide units from the donor molecules UDP-glucuronic acid (UDP-GlcUA) and UDP-N-acetylglucosamine

43 oniae requires UDP-glucose (UDP-Glc) and UDP-glucuronic acid (UDP-GlcUA) for production of the [3)-be

44 resence of protein-mediated transport of UDP-glucuronic acid (UDP-GlcUA) in rat liver endoplasmic ret

45 lcUA-(1-] from UDP-glucose (UDP-Glc) and UDP-glucuronic acid (UDP-GlcUA) is catalysed by the type 3 s

46 Although UDP-glucuronic acid (UDP-GlcUA) is most commonly employed as

47 nic acid moiety from the uridine diphosphate-glucuronic acid (UDP-GlcUA) to the common linkage region

48 applied to develop a synthesis of protected glucuronic acid 1, a key intermediate in the synthesis o

49 ed a rare sequence consisting of consecutive glucuronic acid 2-O-sulfate residues as selectively targ

50 inant UAS homologs all form UDP-Api from UDP-glucuronic acid albeit in different amounts.

51 Mutations in a previously identified UDP-glucuronic acid allosteric binding site decreased the bi

52 We found that depletion of UDP-glucuronic acid altered the expression of PPAR-gamma tar

53 shown to hydrolyze terminal alpha-1,2-linked glucuronic acid and 4-O-methylated glucuronic acid from

54 backbone of xylosyl residues substituted by glucuronic acid and 4-O-methylglucuronic acid (collectiv

55 that although wild-type xylans contain both glucuronic acid and 4-O-methylglucuronic acid residues,

56 ranosiduronic acids (glucuronides) using UDP-glucuronic acid and acceptor substrates such as drugs, s

57 lation, we identified O-acetylation of alpha-glucuronic acid and alpha-glucose in 9A PS.

58 utations in UXS1 lead to accumulation of UDP-glucuronic acid and alterations in nucleotide metabolism

59 es with low ratios of xylose to 4-O-methyl-D-glucuronic acid and appears to require two 4-O-methyl-D-

60 in itself, and this binding was inhibited by glucuronic acid and chondroitin sulfate.

61 hesized in the assay was composed of Glc and glucuronic acid and could be degraded to a low molecular

62 dependent oxidation of the 4''-OH of the UDP-glucuronic acid and decarboxylation of the UDP-4-keto-gl

63 f acidic O-linked glycoconjugates containing glucuronic acid and galactose as well as a reduction of

64 microfibrils had a higher content of (methyl)glucuronic acid and galactose in tension wood than in no

65 cose and rhamnose), and two hexuronic acids (glucuronic acid and galacturonic acid).

66 dation of not only alginate, but poly-beta-D-glucuronic acid and hyaluronic acid as well.

67 o its ability to sequester intracellular UDP-glucuronic acid and inhibition of hyaluronan synthase tr

68 tabolites; quercetin-3'-sulfate, quercetin-3-glucuronic acid and isorhamnetin-3-glucuronic acid were

69 The exquisite complementarity between glucuronic acid and its binding site is highlighted by t

70 ows a variability along their sequence, as d-glucuronic acid and its C5 epimer, l-iduronic acid, can

71 ed that the resulting mutant lacked both UDP-glucuronic acid and its downstream product, UDP-xylose,

72 ible for the oxidation of UDP-glucose to UDP-glucuronic acid and its subsequent decarboxylation to UD

73 accommodation of alpha1,2-linked 4-methyl-D-glucuronic acid and L-arabinofuranose side chains.

74 ase responsible for the interconversion of d-glucuronic acid and l-iduronic acid residues encodes a t

75 ide composed of repeating disaccharides of D-glucuronic acid and N-acetyl-D-glucosamine (GlcNAc).

76 nctional chondroitin synthase K4CP catalyzes glucuronic acid and N-acetylgalactosamine transfer activ

77 block, and the two monosaccharide components glucuronic acid and N-acetylglucosamine and identify mar

78 long linear polymer composed of alternating glucuronic acid and N-acetylglucosamine residues, is an

79 onsisting of repeating disaccharide units of glucuronic acid and N-acetylglucosamine.

80 reaction of appropriately substituted azido-glucuronic acid and propargyluted N-acetyl glucosamine a

81 and two quercetin metabolites (quercetin-3-O-glucuronic acid and quercetin-3-O-sulfate) significantly

82 e propose a binding model for NAD(+) and UDP-glucuronic acid and the involvement of residues T(432),

83 catalyzes the conjugation of bilirubin with glucuronic acid and thus enhances bilirubin elimination;

84 eds in three chemical steps via UDP-4-keto-D-glucuronic acid and UDP-4-keto-pentose intermediates.

85 UXNAcS is specific and cannot utilize UDP-glucuronic acid and UDP-galacturonic acid as substrates.

86 olved in HA synthesis and uses cytosolic UDP-glucuronic acid and UDP-GlcNAc as substrates.

87 at synthesize the building blocks of HA, UDP-Glucuronic acid and UDP-N-Acetyl-Glucosamine, as well as

88 ynthases (HAS1-3), which use cytoplasmic UDP-glucuronic acid and UDP-N-acetylglucosamine as substrate

89 s beta-glucuronidase enzymes that remove the glucuronic acid as a carbon source, effectively reversin

90 by the ORF atu2297, with UDP-glucose or UDP-glucuronic acid as sugar donors.

91 A Cer analogue with a D-glucuronic acid attached at the primary hydroxyl of N-pa

92 tic change of the reaction selectivity, with glucuronic acid being formed as the major product.

93 magnetic resonance studies confirmed that a glucuronic acid beta1,4-xylose disaccharide synthesized

94 resolution apo crystal structure of the UDP-glucuronic acid binding domain of human UGT isoform 2B7

95 ncoded protein is closely related to the UDP-glucuronic acid binding site consensus sequence, and the

96 A calcium-dependent glucuronic acid binding site shows distinctive structura

97 The deletion of either sequence abolishes glucuronic acid but not N-acetylgalactosamine transfer a

98 ectins, is produced from the precursor UDP-D-glucuronic acid by the action of glucuronate 4-epimerase

99 Biosynthesis of UDP-glucuronic acid by UDP-glucose 6-dehydrogenase (UGDH) oc

100 scovered that the published sequence for the glucuronic acid C5-epimerase responsible for the interco

101 t has an overall 37% homology to the human D-glucuronic acid C5-epimerase.

102 The synthesis of UDP-glucuronic acid can alter the NAD(+)/NADH ratio via the

103 residues predicted to interact with the UDP-glucuronic acid cofactor exhibited significantly impaire

104 Compound 5e was converted to beta-glucuronic acid conjugate 6e by the action of pig liver

105 or each analyte; a mixture of 1-pyOH and its glucuronic acid conjugate can be analyzed in 30 min.

106 nantly excreted (>87%) in human urine as the glucuronic acid conjugate, whereas the relative abundanc

107 iver, intestine and kidney, and catalyze the glucuronic acid conjugation of both endogenous compounds

108 recombinant human UGT isoforms, we show that glucuronic acid conjugation of the model substrate, (-)-

109 (UDP-GlcA) is irreversibly catalyzed by UDP-glucuronic acid decarboxylase (UXS).

110 iosynthesis of UDP-xylose is mediated by UDP-glucuronic acid decarboxylase, which converts UDP-glucur

111 ransmembrane protein that functions as a UDP-glucuronic acid decarboxylase.

112 coccal sequence as putatively encoding a UDP-glucuronic acid decarboxylase.

113 Acetate or glucuronic acid decorations are exclusively found on eve

114 uronic acid degradation at pH 5, poly-beta-D-glucuronic acid degradation at pH 7, and alginate degrad

115 ndogenous and exogenous chemicals by linking glucuronic acid donated by UDP-glucuronic acid to a lipo

116 o glycoside (25) with a trichloroacetimidate glucuronic acid donor (13), using a catalytic amount of

117 The Glc-GlcA disaccharide, featuring the glucuronic acid donor moiety, proved to be the most prod

118 We demonstrated that lpsL encoded a UDP-glucuronic acid epimerase activity that was reduced in t

119 igh-resolution crystal structures of the UDP-glucuronic acid epimerase from Bacillus cereus The geome

120 a gene previously predicted to encode a UDP-glucuronic acid epimerase.

121 espect to chain length, sulfate content, and glucuronic acid epimerization content, resulting in a di

122 Although glucuronic acid esters are often considered to be of ver

123 eactions revealed that the reactivity of the glucuronic acid esters studied is sufficient to provide

124 The relative reactivity of glucuronic acid esters was established in a series of co

125 ,2-linked glucuronic acid and 4-O-methylated glucuronic acid from the plant cell wall polysaccharide

126 Reaction of beta-glucuronic acid glycoside of 4-hydroxy-3-nitrobenzyl alc

127 ogether with the aglycon and alpha- and beta-glucuronic acid hydrolysis products.

128 may be close to the 3-hydroxyl group of beta-glucuronic acid in a HNK-1 acceptor.

129 esonance that revealed a crucial role of the glucuronic acid in antibody binding.

130 w that the carboxyl group on nonreducing end glucuronic acid in dodecasaccharide motif is important f

131 o distinguish the epimers iduronic acid from glucuronic acid in heparan sulfate tetrasaccharides and

132 a1-4 linkage between N-acetylglucosamine and glucuronic acid in hyaluronan polymers via a substrate-a

133 he content of the polysaccharide component D-glucuronic acid in the biofilm.

134 s undergo detoxification by conjugation with glucuronic acid in the liver via the action of UDP-glucu

135 Nrf2 promoted conjugation of ABP with glucuronic acid in the liver, increasing urinary excreti

136 n, ideal for decarboxylation of UDP-4-keto-D-glucuronic acid in the second chemical step.

137 E, quercetin-3-O-glucoside and quercetin-3-O-glucuronic acid inhibited significantly (p<0.05) ACE act

138 c acid and decarboxylation of the UDP-4-keto-glucuronic acid intermediate.

139 The oxidative decarboxylation of UDP-glucuronic acid is catalyzed by the 345-residue C-termin

140 In this process, glucuronic acid is conjugated to a drug or a drug metabo

141 UDP-glucuronic acid is converted to UDP-galacturonic acid en

142 d-Glucuronic acid is further metabolized to xylitol via th

143 ctivity of B3GAT1, we were able to show that glucuronic acid is present on antennae of plasma glycopr

144 pletion of the hyaluronic acid precursor UDP-glucuronic acid is sufficient to inhibit several mesench

145 In humans, conjugation with glucuronic acid is the most important phase II metabolic

146 In mammalian organisms, UDP-glucuronic acid is typically used in the transfer reacti

147 at is specific for the l-rhamnose-alpha1,4-d-glucuronic acid linkage that caps the side chains of com

148 Glucuronic acid linked prodrugs of O(6)-benzylguanine an

149 ated Az29, possesses two PEtn moieties and a glucuronic acid linked to a Gal-extended Nz28.

150 ranched surface structure containing glucose-glucuronic acid linked to a glucose-rhamnose-rhamnose-rh

151 vered that heparanase cleaves the linkage of glucuronic acid linked to glucosamine carrying 6-O-sulfo

152 Glucuronic acid modification was observed in E. coli B,

153 leavage of ester linkages between lignin and glucuronic acid moieties on glucuronoxylan in plant biom

154 e of ester linkages found between lignin and glucuronic acid moieties on glucuronoxylan in plant biom

155 f sugar residues and epimerizations of their glucuronic acid moieties.

156 etraazacyclododecane) bearing a pendant beta-glucuronic acid moiety connected by a self-immolative li

157 GlcAT-I transfers a glucuronic acid moiety from the uridine diphosphate-gluc

158 cid hydrolysis, resulting in a Xyl:arabinose:glucuronic acid molar ratio of approximately 105:34:1.

159 scribed, which arises due to the addition of glucuronic acid on the third heptose with a concomitant

160 transferase GUX1, and so the even pattern of glucuronic acid on the xylan is lost.

161 residues in the capsule are derived from UDP-glucuronic acid or its metabolites.

162 di- or trisaccharide and at position 6 with glucuronic acid or rhamnosyl glucuronic acid.

163 of acidic sugars N-acetylneuraminic acid and glucuronic acid out of lysosomes.

164 e-uronic acid intermediate that results from glucuronic acid oxidation, placing the C4' atom in posit

165 lation of the bacterial N-acetylglucosaminyl-glucuronic acid polymer K5 under conditions where the ho

166 effects in rodents, and are conjugated with glucuronic acid prior to excretion in human urine.

167 We propose that the regulation of UDP-glucuronic acid production in a specific subset of vulva

168 indicating that an alternate pathway for UDP-glucuronic acid production was not used.

169 d from partial desulfation demonstrated that glucuronic acid rather than iduronic acid residues are i

170 lysaccharide composed of N-acetylglucosamine-glucuronic acid repeats, is found in the extracellular m

171 acid and appears to require two 4-O-methyl-D-glucuronic acid residues for substrate recognition and/o

172 on, BtGH115A, hydrolyzes terminal 4-O-methyl-glucuronic acid residues from decorated arabinogalactan

173 dase was used to remove nonreducing-terminal glucuronic acid residues from oligosaccharides.

174 ily 2 glycosylhydrolases that cleaves beta-D-glucuronic acid residues from the nonreducing termini of

175 ly incorporated xylose (Xyl), arabinose, and glucuronic acid residues from their corresponding uridin

176 Odd-numbered oligosaccharides with terminal glucuronic acid residues isolated from hyaluronidase dig

177 ults in a specific defect in the addition of glucuronic acid residues onto xylans.

178 iency, both contain a trisaccharide with two glucuronic acid residues that enabled the identification

179 ride of alternating N-acetyl-glucosamine and glucuronic acid residues, is ubiquitously expressed in v

180 ride units of N-acetyl-D-galactosamine and d-glucuronic acid residues, modified with sulfated residue

181 idues but lacks any 2-O-sulfated iduronic or glucuronic acid residues.

182 rface than thought previously, such that a D-glucuronic acid ring makes stacking and ionic interactio

183 ynthesis mutants, such as the replacement of glucuronic acid side chains with methylglucuronic acid s

184 s (MS) I and II through their coupling at C3 glucuronic acid site with dodecylamine.

185 (GXMT) that catalyzes 4-O-methylation of the glucuronic acid substituents of this polysaccharide.

186 GUX1 (glucuronic acid substitution of xylan 1) and GUX2, recen

187 noglycan composed of N-acetylglucosamine and glucuronic acid subunits.

188 ernating beta1,3-N-acetylglucosamine-beta1,4-glucuronic acid sugar chain by the sequential addition o

189 nd xenobiotic compounds by linking them to a glucuronic acid sugar for GI excretion.

190 UGTs catalyze the covalent addition of glucuronic acid sugar moieties to a host of therapeutics

191 ects observed for amino acids closest to the glucuronic acid sugar transferred to the acceptor molecu

192 (Ssp) show homology to genes involved in UDP-glucuronic acid synthesis.

193 ls by linking glucuronic acid donated by UDP-glucuronic acid to a lipophilic acceptor substrate.

194 "reversible" catalytic mode by converting a glucuronic acid to an iduronic acid residue, and vice ve

195 lso serve as a one-way catalyst to convert a glucuronic acid to an iduronic acid residue, displaying

196 coded by PsUGT1 catalyzes conjugation of UDP-glucuronic acid to an unknown compound.

197 Chst10 adds sulfate to glucuronic acid to form a carbohydrate antigen, HNK-1, i

198 precedented oxidative decarboxylation of UDP-glucuronic acid to form uridine 5'-(beta-l-threo-pentapy

199 )-dependent oxidative decarboxylation of UDP-glucuronic acid to generate a UDP-4'-keto-pentose sugar

200 ehydrogenase, which is capable of converting glucuronic acid to glucaric acid.

201 ylgalactosamine may precede epimerization of glucuronic acid to iduronic acid during dermatan sulfate

202 san with C(5)-epimerase converts some of the glucuronic acid to iduronic acid, thus becoming a substr

203 The HS C(5)-epimerase converts glucuronic acid to iduronic acid.

204 fication reactions is the epimerization of D-glucuronic acid to its C5-epimer L-iduronic acid, which

205 UGT1As add glucuronic acid to many drugs, modifying their activity

206 UGT1As add glucuronic acid to many drugs.

207 3)-glucuronyltransferases, one of which adds glucuronic acid to protein-linked galactose-beta(1, 4)-N

208 the NAD(+)-dependent decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and (ii) the N-1

209 One activity is to decarboxylate UDP-glucuronic acid to UDP-beta-l-threo-pentopyranosyl-4''-u

210 hase (AXS) catalyzes the conversion of UDP-D-glucuronic acid to UDP-D-apiose and UDP-D-xylose.

211 shown to encode an enzyme that converts UDP-glucuronic acid to UDP-xylose for capsule biosynthesis,

212 neoformans gene catalyzed conversion of UDP-glucuronic acid to UDP-xylose, as confirmed by NMR analy

213 ase (UXS) catalyzes decarboxylation of UDP-D-glucuronic acid to UDP-xylose.

214 ronic acid decarboxylase, which converts UDP-glucuronic acid to UDP-xylose.

215 +-dependent oxidative decarboxylation of UDP-glucuronic acid to yield the UDP-4''-ketopentose, uridin

216 olase-like catalytic mechanism to facilitate glucuronic acid transfer.

217 d II enzymes (cytochrome P450 (CYP), uridine glucuronic acid transferase (UGT), and sulfotransferase

218 into two single-action glycosyltransferases (glucuronic acid transferase and N-acetylglucosamine tran

219 ctionalized side chain incorporated into the glucuronic acid unit that is attached to a triterpenoid

220 The abundance of the 4-O-methyl-alpha-d-glucuronic acid was not previously reported.

221 ercetin-3-glucuronic acid and isorhamnetin-3-glucuronic acid were effective at physiological concentr

222 mposed of disaccharide units of GlcNAc and d-glucuronic acid with alternating beta-1,4 and beta-1,3 g

223 metabolites (methylated and conjugated with glucuronic acid) across hCMEC/D3 cells (a blood-brain ba

224 M) enhanced the potency of UDPG (but not UDP-glucuronic acid) by 7-fold.

225 Addition of the terminal residue (glucuronic acid) could not be detected; however, activit

226 tive cleavage of myo-inositol (MI) to give d-glucuronic acid, a committed step in MI catabolism.

227 doreductase that converts UDP-glucose to UDP-glucuronic acid, a key component of specific proteoglyca

228 s for the sugar donors UDP-galactose and UDP-glucuronic acid, although UDP-glucose was always preferr

229 des UDP-glucose dehydrogenase which produces glucuronic acid, an essential component for the synthesi

230 ssive oxidations of UDP-glucose to yield UDP-glucuronic acid, an essential precursor for matrix polys

231 DP-glucose dehydrogenase (Ugd) generates UDP-glucuronic acid, an important precursor for the producti

232 Chondroitin sulfate type C (CSC) contains glucuronic acid, and 90% of the GalNAc residues are sulf

233 Chondroitin sulfate type A (CSA) contains glucuronic acid, and 90% of the GalNAc residues are sulf

234 xylosyl residues is decorated by occasional glucuronic acid, and approximately one-half of the xylos

235 dic, alpha-fucosidic, alpha-mannosidic, beta-glucuronic acid, and beta-glucosamine linkages upon acti

236 ow that hemicellulose branches of arabinose, glucuronic acid, and especially glucuronate strengthen t

237 al other monosaccharides, including glucose, glucuronic acid, and N-acetylmannosamine, do not express

238 gy, we used purified S. equisimilis HAS, UDP-glucuronic acid, and UDP[beta-32P]-Glc-NAc to radiolabel

239 The UGT1 and UGT2 enzymes use UDP-glucuronic acid, and UGT3 enzymes use UDP-N-acetylglucos

240 component of the capsule (and, potentially, glucuronic acid, any-N-acetylated sugar, or ribitol).

241 e content of UDP-N-acetylhexosamines and UDP-glucuronic acid, correlating with the expression level o

242 4" oxidation and C-6" decarboxylation of UDP-glucuronic acid, followed by the C-4" transamination of

243 and C-6" decarboxylation of [alpha-(32)P]UDP-glucuronic acid, followed by transamination to generate

244 fucose, d-mannose, d-galactose, d-glucose, d-glucuronic acid, N-acetyl-d-galactosamine, and N-acetyl-

245 ccus neoformans comprises manose, xylose and glucuronic acid, of which mannose is the major constitue

246 ansport rate for N-acetylneuraminic acid and glucuronic acid, suggesting that it may be directly invo

247 specificity and allows phosphorylation of d-glucuronic acid, the 4-epimer of GalA.

248 charides containing terminal 4,5-unsaturated glucuronic acid, the nonreducing end disaccharide moiety

249 found in natural polysaccharides containing glucuronic acid, the oxidation of the primary alcohol at

250 cerevisiae expressing SQV-7 transported UDP-glucuronic acid, UDP-N-acetylgalactosamine, and UDP-gala

251 use steroid hormones are often conjugated to glucuronic acid, we hypothesized that Chst10 sulfates gl

252 talyzes the conversion of UDP-glucose to UDP-glucuronic acid, which is essential for the biosynthesis

253 Glucuronic acid, which is transferred to the AGP glycan

254 gh content of the nonsulfated disaccharide D-glucuronic acid-acetylated glucosamine (GlcA-GlcNAc).

255 nd glycolipid, termed Gl-X (mannose-alpha1-4-glucuronic acid-alpha1-diacylglycerol), which function a

256 a variety of monodisperse hyaluronan (beta 4-glucuronic acid-beta 3-N-acetylglucosamine (HA)) oligosa

257 duced repeating units of [-3-xylose-alpha1,3-glucuronic acid-beta1-].

258 uctions in the amount of [-3-xylose-alpha1,3-glucuronic acid-beta1-]n (hereafter referred to as LARGE

259 accharide repeating unit [-3-xylose-alpha1,3-glucuronic acid-beta1-]n by like-acetylglucosaminyltrans

260 - O- tert-butyl diphenyl silyl group and a d-glucuronic acid-containing disaccharide thioglycoside wi

261 Only glucuronic acid-containing ligands produced complexes, a

262 enosine diphosphate-activated platelets, UDP-glucuronic acid-dependent bilirubin conjugation was dete

263 al preparations resulted in no metabolite or glucuronic acid-HPPH conjugate production.

264 xylan, generating products with a 4-O-methyl-glucuronic acid-substituted xylose residue one position

265 polymer from UDP-N-acetylglucosamine and UDP-glucuronic acid.

266 UDP-glycosyltransferase UGT co-substrate UDP-glucuronic acid.

267 sulfate to the iduronic acid but not to the glucuronic acid.

268 fated heparosan, a polysaccharide containing glucuronic acid.

269 DP-N-acetylglucosamine (UDP-GlcNAc), and UDP-glucuronic acid.

270 ansformed cells on minimal medium containing glucuronic acid.

271 h as hormones by reversible conjugation with glucuronic acid.

272 se, d-glucose, d-arabinose, d-rhamnose and d-glucuronic acid.

273 rface, which selectively oxidizes glucose to glucuronic acid.

274 a salt bridge with the carboxylate group of glucuronic acid.

275 daily diet and environment by conjugation to glucuronic acid.

276 s two oxidations of UDP-glucose to yield UDP-glucuronic acid.

277 position 6 with glucuronic acid or rhamnosyl glucuronic acid.

278 d environmental chemicals via conjugation to glucuronic acid.

279 mediate that is synthesized by ArnA from UDP-glucuronic acid.

280 neurotoxic bilirubin by conjugating it with glucuronic acid.

281 a pathway for l-Ara4N biosynthesis from UDP-glucuronic acid.

282 e polysaccharide contained galactosamine and glucuronic acid.

283 the related IAG sequence, where G is alpha-D-glucuronic acid.

284 inked mannan substituted with D-xylose and D-glucuronic acid.

285 e HA or any other molecules known to contain glucuronic acid.

286 lycyrrhizin (GL) by hydrolysing one terminal glucuronic acid.

287 cid, rhamnose, mannose, xylose and traces of glucuronic acid.

288 ha-D-glucose, beta-D-glucose, rhamnose and D-glucuronic acid.

289 xtracts of the mutants completely lacked UDP-glucuronic acid:Galbeta1,3Gal-R glucuronosyltransferase

290 nts may be linked to the availability of UDP-glucuronic acid; therefore UGDH is an intriguing therape

291 ctive UDP-sugars to the non-reducing end of [glucuronic acid]beta1-3[galactose]beta1-O-naphthalenemet

292 with UDP and the acceptor substrate analog [glucuronic acid]beta1-3[galactose]beta1-O-naphthalenemet

293 n those measured on a mixture of pyruvic and glucuronic acids (logK = 2.2), which are the two constit

294 ccharide that is decorated with alpha-linked glucuronic and/or methylglucuronic acid (GlcA/MeGlcA).

295 residue arabinogalactan subunit with paired glucuronic carboxyls.

296 Glucuronic (GlcA) and iduronic acids (IdoA) were subsequ

297 Heparan sulfate consists of glucosamine and glucuronic/iduronic acid repeating disaccharides with va

298 ly bind anionic residues (sulfated rhamnose, glucuronic/iduronic acid).

299 fers the sulfo group to the 2-OH-position of glucuronic or iduronic acid.

300 e conformation of C-5 of the hexuronic acid (glucuronic versus iduronic) is not crucial, and (c) addi