ライフサイエンスコーパス: glucuronide conjugate

1 it was eliminated 57.7 +/- 0.36% faster as a glucuronide conjugate.

2 metabolites and the corresponding sulfo and glucuronide conjugates.

3 echin after enzymatic release of sulfate and glucuronide conjugates.

4 over-the-counter drugs as their sulfate and glucuronide conjugates.

5 a significant factor in renal elimination of glucuronide conjugates.

6 L) at 10 mg/kg was due to the formation of O-glucuronide conjugate by phase 2 metabolism.

7 ty is expected to reduce the reactivation of glucuronide-conjugated drugs in the intestine, thereby r

8 The glucuronide conjugates ethinylestradiol-3-glucuronide an

9 st demonstrated by the identification of two glucuronide-conjugated metabolite standards spiked in ur

10 Several glucuronide-conjugated metabolites of LTB4 were characte

11 ound to have great potential for identifying glucuronide-conjugated metabolites, as well as other kin

12 res were structurally annotated as potential glucuronide-conjugated metabolites, resulting in the ide

13 (PDMS2E-DIA), to comprehensively profile the glucuronide-conjugated metabolome.

14 ent glucuronidation to form a novel O-linked glucuronide conjugate, O-(beta-D-glucosidurony1)-2-hydro

15 es and the urinary excretion level of the N2-glucuronide conjugate of 2-hydroxyamino-MeIQx--N2-(beta-

16 immune cytopenia caused by sensitivity to a glucuronide conjugate of a drug metabolite.

17 tographic (HPLC) analysis, and found to be a glucuronide conjugate of a known DCF metabolite, 4'-hydr

18 ughput method to directly analyze the intact glucuronide conjugate of HP (HP-G) in human urine after

19 , produced a single detectable metabolite, a glucuronide conjugate of N-hydroxy-PhIP.

20 y either bacteria-mediated hydrolysis of the glucuronide conjugate of the active metabolite 7-ethyl-1

21 e metabolites were identified as sulfate and glucuronide conjugates of a ring hydroxy-substituted met

22 uid chromatography (HPLC) was used to detect glucuronide conjugates of BPD formed in vitro.

23 ences in the pharmacokinetics of sulfate and glucuronide conjugates of isoflavones.

24 rase (UGT) enzymes catalyze the formation of glucuronide conjugates of phase II metabolism.

25 Glucuronide conjugates of the estrogen D-ring (100 micro

26 We hypothesized that glucuronide conjugates of xenobiotics, such as the antic

27 se activity was stimulated by bile acids and glucuronide conjugates, reaching 170 +/- 28 nmol min-1 m

28 und decrease in the biliary clearance of the glucuronide conjugates was observed in Bcrp-deficient mo

29 Because Mrp3 preferentially transports glucuronide conjugates, we investigated the in vivo disp

30 Our results revealed that while most glucuronide conjugates were completely transformed follo

31 Unlike in rats, where sulfate and glucuronide conjugates were excreted into bile predomina

32 roid conjugates in all sample types, whereas glucuronide conjugates were hydrolyzed in the presence o

33 Several classes of glucuronide conjugates, which include acyl glucuronides,