ライフサイエンスコーパス: glutamate carboxypeptidase

1 so known as AEG-1) and PGCP (encoding plasma glutamate carboxypeptidase).

2 e antigen and to the jejunal folylpoly-gamma-glutamate carboxypeptidase.

3 or Lys) or methotrexate, cleaved by clan MH glutamate carboxypeptidases.

4 y developed to assay hydrolytic activity for glutamate carboxypeptidases.

5 MIP-1072 and MIP-1095 potently inhibited the glutamate carboxypeptidase activity of PSMA (K(i) = 4.6

6 Glutamate carboxypeptidase activity was present in larva

7 nd aminopeptidases, and features of membrane glutamate carboxypeptidase can be deduced from the TfR s

8 The complete folylpoly-gamma-glutamate carboxypeptidase cDNA was isolated from a pig

9 ptidase hydrolysed a synthetic substrate for glutamate carboxypeptidases (FAEE, C-terminal Glu), but

10 myl folates by the action of folylpoly-gamma-glutamate carboxypeptidase (FGCP), an enzyme that is anc

11 PSMA acts as a glutamate carboxypeptidase (GCPII) on small molecule sub

12 Jejunal folylpoly-gamma-glutamate carboxypeptidase hydrolyzes dietary folates pr

13 onoclonal antibody to native folylpoly-gamma-glutamate carboxypeptidase identified a glycoprotein at

14 Glutamate carboxypeptidase II (GCP II) catalyzes the ext

15 The enzyme glutamate carboxypeptidase II (GCP II) has been cloned f

16 or proteins in schizophrenia and to quantify glutamate carboxypeptidase II (GCP II) in order to explo

17 Two representative glutamate carboxypeptidase II (GCP II) inhibitors, 2-(hy

18 The expression of glutamate carboxypeptidase II (GCP II) is reduced in sel

19 However, the catalytic enzyme glutamate carboxypeptidase II (GCP II) rapidly hydrolyze

20 ore and after NAAG hydrolysis with exogenous glutamate carboxypeptidase II (GCP II) using high-perfor

21 The NAAG hydrolyzing enzyme, glutamate carboxypeptidase II (GCP II), activity was nor

22 ed and tested for their abilities to inhibit glutamate carboxypeptidase II (GCP II).

23 e synthesized and evaluated as inhibitors of glutamate carboxypeptidase II (GCP II, EC 3.4.17.21).

24 mbers include transferrin receptor 2 (TfR2), glutamate carboxypeptidase II (GCP2 or PSMA), N-acetylat

25 Glutamate carboxypeptidase II (GCPII or prostate-specifi

26 Glutamate carboxypeptidase II (GCPII) encodes for intest

27 Inhibition of glutamate carboxypeptidase II (GCPII) has been shown to

28 Glutamate carboxypeptidase II (GCPII) has emerged as a p

29 Urea-based, low molecular weight ligands of glutamate carboxypeptidase II (GCPII) have demonstrated

30 The neuropeptidase glutamate carboxypeptidase II (GCPII) hydrolyzes N-acety

31 A series of thiol-based glutamate carboxypeptidase II (GCPII) inhibitors have be

32 delta-Thiolactones derived from thiol-based glutamate carboxypeptidase II (GCPII) inhibitors were ev

33 We then evaluated glutamate carboxypeptidase II (GCPII) inhibitors, known

34 Prostate-specific membrane antigen (PSMA) or glutamate carboxypeptidase II (GCPII) is a promising tar

35 Glutamate carboxypeptidase II (GCPII) is an exopeptidase

36 Inhibition of glutamate carboxypeptidase II (GCPII) is effective in pr

37 Human glutamate carboxypeptidase II (GCPII) is involved in neu

38 to NAA and glutamate by the catalytic enzyme glutamate carboxypeptidase II (GCPII) reducing presynapt

39 Because glutamate carboxypeptidase II (GCPII) regulates both fol

40 eting the active site as well as exosites of glutamate carboxypeptidase II (GCPII), a prostate cancer

41 Glutamate carboxypeptidase II (GCPII), coded by the gene

42 orters/receptor (FT/R) and folate hydrolase, glutamate carboxypeptidase II (GCPII), from the terminal

43 cific membrane antigen (PSMA), also known as glutamate carboxypeptidase II (GCPII), is a suitable tar

44 Glutamate carboxypeptidase II (GCPII), localized on the

45 involving potent and selective inhibitors of glutamate carboxypeptidase II (GCPII), which converts th

46 MTHFR), reduced folate carrier 1 (RFC1), and glutamate carboxypeptidase II (GCPII).

47 Glutamate carboxypeptidase II (GCPII, NAALADase, or NAAG

48 anisms, such as increased kynurenic acid and glutamate carboxypeptidase II expression, are especially

49 ptidase-like 2 (NAALADL2) is a member of the glutamate carboxypeptidase II family, best characterized

50 Glutamate carboxypeptidase II may modulate excitatory ne

51 ic acid (1, 2-PMPA) is a potent inhibitor of glutamate carboxypeptidase II which has demonstrated rob

52 ith a catalytic mechanism similar to that of glutamate carboxypeptidase II yet distinct substrate spe

53 by the NAALADL1 gene, is a close homolog of glutamate carboxypeptidase II, a metallopeptidase that h

54 Inhibitors of glutamate carboxypeptidase II, an enzyme that inactivate

55 dic dipeptidase (NAAG peptidase activity) or glutamate carboxypeptidase II, and may also act as a NAA

56 1 is a potent hydroxamate-based inhibitor of glutamate carboxypeptidase II.

57 from the cross-reactivity of PSMA ligands to glutamate carboxypeptidase III (GCPIII), it may be conve

58 ward GCPII than its closest human homologue, glutamate carboxypeptidase III (GCPIII).

59 membrane antigen (PSMA) is a membrane-bound glutamate carboxypeptidase overexpressed in many forms o

60 ma proteins was identified, including plasma glutamate carboxypeptidase (PGCP) and two secreted phosp

61 arge family of peptidases exemplified by the glutamate carboxypeptidase PSMA.