ライフサイエンスコーパス: glutamine synthetase

1 rocyte-restricted glutamate transporters and glutamine synthetase).

2 ression of the beta-catenin surrogate target glutamine synthetase.

3 eraction between GlnR and feedback-inhibited glutamine synthetase.

4 ding was not activated by feedback-inhibited glutamine synthetase.

5 This constitutive repression did not require glutamine synthetase.

6 tection of the early glial markers GLAST and glutamine synthetase.

7 was the specific activity of the key enzyme, glutamine synthetase.

8 was most easily studied in strains that lack glutamine synthetase.

9 amate dehydrogenase, glutamate synthase, and glutamine synthetase.

10 and the second also had a partially impaired glutamine synthetase.

11 of TnrA is required for the interaction with glutamine synthetase.

12 o regulate the AmtB ammonium transporter and glutamine synthetase.

13 es of mutants that altered the regulation by glutamine synthetase.

14 e site to bring about feedback inhibition of glutamine synthetase.

15 ystem, a putative formate transporter, and a glutamine synthetase.

16 effects on the catalytic characteristics of glutamine synthetase.

17 e acid-labile substrates such as apyrase and glutamine synthetase.

18 were labeled with GFAP and Muller cells with glutamine synthetase.

19 response, including the ammonia-assimilating glutamine synthetase.

20 ression was confirmed by colocalization with glutamine synthetase.

21 ied with antibodies directed against S100 or glutamine synthetase.

22 an inactive complex with feedback-inhibited glutamine synthetase.

23 through a protein- protein interaction with glutamine synthetase.

24 tic properties similar to those of wild-type glutamine synthetase.

25 amma polypeptide of the native and denatured glutamine synthetase.

26 t for normal posttranslational regulation of glutamine synthetase.

27 ll maturation markers carbonic anhydrase and glutamine synthetase.

28 tive for glial fibrillary acidic protein and glutamine synthetase.

29 is inhibitor than a representative mammalian glutamine synthetase.

30 ogen-regulated promoters and the activity of glutamine synthetase.

31 enases, respectively; and (iv) GLN1 encoding glutamine synthetase.

32 y histology and expression of the HCC marker glutamine synthetase.

33 her and express markers, including Glast and glutamine synthetase.

34 ease in the Wnt pathway targets cyclin-D1 or glutamine synthetase.

35 ctive astrocytes downregulated expression of glutamine synthetase.

36 o decreased the association between GFAP and glutamine synthetase.

37 h bears significant similarity with GSI-type glutamine synthetases.

38 Glutamine synthetase 1 is regulated in different plants

39 a bona fide plastid transit peptide from the glutamine synthetase 2 gene does not restore DMI1 functi

40 atis bacteria expressing the M. tuberculosis glutamine synthetase A (glnA) gene or open reading frame

41 er but had only a minimal effect on cellular glutamine synthetase, a finding consistent with failure

42 We investigated whether a deficiency in glutamine synthetase, a key enzyme in catabolism of extr

43 in phosphorylated STAT3 was colocalized with glutamine synthetase, a Muller cell marker, by immunocyt

44 However, the degradation of chloroplast glutamine synthetase, a potential substrate for the ClpP

45 The corresponding antigens were derived from glutamine synthetase, a transitional endoplasmic reticul

46 te synthase, trehalose-6-phosphate synthase, glutamine synthetases, a protein (LIM17) that has been i

47 treatment led to a deficiency in hippocampal glutamine synthetase activity by 82-97% versus saline.

48 glnA1 expression, suggesting that decreased glutamine synthetase activity contributes to glutamate a

49 rotein, was stable only in a strain in which glutamine synthetase activity is not inhibited by NH(4)(

50 cDNA is reported as well as the finding that glutamine synthetase activity is present in liver but no

51 growth in MN medium is apparently due to low glutamine synthetase activity, because a DeltaglnD strai

52 n of Tyr-397 is central to the regulation of glutamine synthetase activity, via esterification of the

53 and that this inhibition was dependent upon glutamine synthetase activity.

54 of glnE, potentially encoding a regulator of glutamine synthetase activity.

55 Glutamine synthetase adenylyltranferase (ATase, EC 2.7.7

56 gulating the activities of the PII receptors glutamine synthetase adenylyltransferase (ATase) and the

57 ability of PII to control the activities of glutamine synthetase adenylyltransferase (ATase) but did

58 Glutamine synthetase adenylyltransferase (ATase) regulat

59 ith similar AMP-transferring enzymes such as glutamine synthetase adenylyltransferase or kanamycin nu

60 tion of several transcripts, including XDH1, glutamine synthetase, alanine aminotransferase, catalase

61 Thus, glutamine synthetase, an enzyme of central metabolism, d

62 colytic enzyme; HSP72, a stress protein; and glutamine synthetase, an excitotoxicity-related protein.

63 or that controls TnrA activity, a complex of glutamine synthetase and a feedback inhibitor, such as g

64 bition of caspases-3 and -11 also attenuated glutamine synthetase and fibroblast growth factor-2 expr

65 h zVAD significantly attenuated increases in glutamine synthetase and fibroblast growth factor-2 in t

66 luding stellate morphology and expression of glutamine synthetase and fibroblast growth factor-2.

67 There was a progressive loss of glutamine synthetase and GFAP content and a coincident i

68 ler cell changes in culture included loss of glutamine synthetase and GFAP, with coincident gains in

69 CD9-GFP labeled cells included glutamine synthetase and glial fibrillary acidic protein

70 Exaiptasia glutamine synthetase and glutamate synthase transcripts

71 Finally, our results reveal that two genes, glutamine synthetase and glutamate synthase, which poten

72 ve and glutamate-induced injury and restored glutamine synthetase and glutamate transporter expressio

73 his was enhanced by inhibition of astrocytic glutamine synthetase and reversed or prevented by exogen

74 proteins, including aquaporin 4, actin, and glutamine synthetase and serine racemase.

75 n and inactivation of glial-related enzymes (glutamine synthetase and the glutamate transporter) know

76 cooperative binding sets the basal level for glutamine synthetase and the regulators of the Ntr respo

77 fibrillary acidic protein (GFAP), vimentin, glutamine synthetase, and alpha smooth muscle actin (alp

78 The cells expressed CRALBP, EGF-R, glutamine synthetase, and alpha-SMA, as judged by confoc

79 histochemical markers (PD-1, cytokeratin 19, glutamine synthetase, and beta-catenin expression).

80 e, an energy-requiring reaction catalyzed by glutamine synthetase, and found that at pH 7, constituti

81 acid residues in bovine serum albumin (BSA), glutamine synthetase, and insulin in the presence of a m

82 hologically normal when stained with an anti-glutamine synthetase antibody.

83 r cells mature in stages: HNK-1 labeling and glutamine synthetase arise earlier than carbonic anhydra

84 t of BDQ-mediated killing, identifying Mtb's glutamine synthetase as a collateral, rather than direct

85 ess nitrogen, the feedback-inhibited form of glutamine synthetase binds to TnrA and blocks DNA bindin

86 from adenosine 5'-triphosphate (ATP) in the glutamine synthetase biosynthetic assay.

87 ons, residual inhibition lost sensitivity to glutamine synthetase blockade, whereas exogenous glutami

88 ransferase (ATase) regulates the activity of glutamine synthetase by adenylylation and deadenylylatio

89 nK in the activation of the adenylylation of glutamine synthetase by ATase.

90 nal enhancers, the hyperosmotic induction of glutamine synthetase by intron 1 is position dependent.

91 Inhibition of glutamine synthetase by methionine sulfoximine led to a

92 hypothesis that a deficiency in hippocampal glutamine synthetase causes recurrent seizures, even in

93 created a novel animal model of hippocampal glutamine synthetase deficiency by continuous (approxima

94 primary pulmonary hypertension, and hepatic glutamine synthetase deficiency.

95 2, SAG19, MT1 (metallothionein), and Atgsr2 (glutamine synthetase), did not show enhanced transcript

96 ort here that the feedback-inhibited form of glutamine synthetase directly interacts with TnrA and bl

97 ibrates across the cytoplasmic membrane, and glutamine synthetase does not manifest an isotope effect

98 Five mutants containing feedback-resistant glutamine synthetases (E65G, S66P, M68I, H195Y, and P318

99 probably correlated with high expression of glutamine synthetase, enzymes utilizing nitrite/nitrate,

100 ular retinaldehyde binding protein (CRALBP), glutamine synthetase, epidermal growth factor receptor (

101 00beta, and CD44, but low immunostaining for glutamine synthetase, excitatory amino-acid transporter

102 mistry was used to study the distribution of glutamine synthetase, expressed by Muller cells, and zon

103 Glutamine synthetase expression was also increased in th

104 ired for precise enhancement of hyperosmotic glutamine synthetase expression.

105 athogenic mycobacteria, all of which release glutamine synthetase extracellularly, but had no effect

106 terial microorganisms, none of which release glutamine synthetase extracellularly.

107 e conserved with active-site residues of the glutamine synthetase family of enzymes.

108 suggest that Dop and PafA are members of the glutamine synthetase fold family of proteins.

109 own with excess nitrogen, feedback-inhibited glutamine synthetase forms a protein-protein complex wit

110 own with excess nitrogen, feedback-inhibited glutamine synthetase forms a protein-protein complex wit

111 f the beta and gamma subunit polypeptides of glutamine synthetase from bean (Phaseolus vulgaris L.) r

112 TgTrx-Px2 protected glutamine synthetase from inactivation by Fe(3+)/DTT, sh

113 ne, suggesting a role for pita in protecting glutamine synthetase from inhibition.

114 High-level expression was achieved using the Glutamine Synthetase Gene Amplification System, and the

115 e show that the upstream enhancer of the rat glutamine synthetase gene is also active, specifically i

116 assay for open reading frame 1 (ORF1) of the glutamine synthetase gene of Neisseria gonorrhoeae was a

117 ression of nif (nitrogen-fixation) and glnA (glutamine synthetase) gene expression in vivo.

118 Here, we show that the enzyme glutamine synthetase (Gln1) forms filaments at low pH an

119 Similarly, glutamine synthetase (Gln1-GFP) foci cycled reversibly i

120 N-limited condition and mutants deficient in glutamine synthetase, gln1-3 and gln1-4.

121 n: asparagine synthetase (ASN1 and ASN2) and glutamine synthetase (GLN2).

122 ixation (nif) gene transcription occurs, and glutamine synthetase (glnA) gene transcription falls to

123 utants which synthesize low levels of active glutamine synthetase (glnA).

124 roteins (bone marrow stromal cell antigen 1, glutamine synthetase [GLNA], laminin subunit beta-2, lys

125 A single peptide from the glutamine synthetase (GlnA1) enzyme was identified in 61

126 The model predicts the responses of glutamine synthetase, GlnB, and GlnK under time-varying

127 odA), L-alanine dehydrogenase (AlaDH), and L-glutamine synthetase (GlnS) proteins.

128 de the VZ also express the astroglial marker glutamine synthetase (Glns).

129 The mRNA levels of glutamine synthetase (GLUL), beta-catenin (CTNNB) and it

130 ipal glutamate and GABA-metabolizing enzymes glutamine synthetase, glutamate dehydrogenase, alpha-ket

131 enteric bacteria consists of three enzymes: glutamine synthetase, glutamate synthase (GOGAT), and gl

132 pression of glial fibrillary acidic protein, glutamine synthetase, glutamate transporter 1 (GLT1), aq

133 at both the tricarboxylic acid cycle and the glutamine synthetase/glutamate synthase cycles are linke

134 Ammonia assimilation by the plastidic glutamine synthetase/glutamate synthase system requires

135 as the nitrogen is scavenged by the urea and glutamine synthetase/glutamine 2-oxoglutarate aminotrans

136 s, which was identified as soybean cytosolic glutamine synthetase GS(1)beta1 by mass spectrometry.

137 to a single monomer of the protein substrate glutamine synthetase (GS(m)), as well as that of unligan

138 s the first step in that recovery, we report glutamine synthetase (GS) activity in highly purified Ar

139 roxynitrite to modify amino acid residues in glutamine synthetase (GS) and BSA is greatly influenced

140 e in Wnt-1, beta-catenin, and known targets, glutamine synthetase (GS) and cyclin-D1, along with a co

141 ression of the ammonium-assimilating enzymes glutamine synthetase (GS) and glutamate dehydrogenase (G

142 of ammonia through the concerted activity of glutamine synthetase (GS) and glutamate synthase (GOGAT)

143 r cells and subsequently in the promotion of glutamine synthetase (GS) and L-Glutamate/L-Aspartate Tr

144 An activity that inhibited both glutamine synthetase (GS) and nitrate reductase (NR) was

145 Glutamine synthetase (GS) and superoxide dismutase (SOD)

146 nit binds directly to the astrocytic protein glutamine synthetase (GS) and that this interaction dete

147 We identify glutamine synthetase (GS) as an enzyme whose activity is

148 se brings about the short-term regulation of glutamine synthetase (GS) by catalyzing the adenylylatio

149 Induction of the enzyme glutamine synthetase (GS) by corticosteroids correlates

150 The regulation of Escherichia coli glutamine synthetase (GS) by reversible adenylylation ha

151 Glutamine synthetase (GS) catalyzes condensation of ammo

152 Glutamine synthetase (GS) catalyzes the ATP-dependent co

153 into glutamate, and the counteracting enzyme glutamine synthetase (GS) cause disturbed glutamate home

154 , which is deactivated by feedback-inhibited glutamine synthetase (GS) during nitrogen excess and sta

155 ruminicola 23 genome encodes three different glutamine synthetase (GS) enzymes: glutamine synthetase

156 In bacteria and yeast, glutamine synthetase (GS) expression is tightly regulate

157 reductase (NR), nitrite reductase (NiR), and glutamine synthetase (GS) from leaves of diploid barley

158 The crystal structure of glutamine synthetase (GS) from Mycobacterium tuberculosi

159 We present the first cloning and study of glutamine synthetase (GS) genes in wheat (Triticum aesti

160 ure of PA5508 from Pseudomonas aeruginosa, a glutamine synthetase (GS) homologue, has been determined

161 genetic analyses suggest that genes encoding glutamine synthetase (GS) III in the prasinophytes evolv

162 ere correlated with changes in expression in glutamine synthetase (GS) in astrocyte-like glia and in

163 The modification of glutamine synthetase (GS) in these glnB mutants appears

164 This study focuses on the mechanism of how glutamine synthetase (GS) inhibits TnrA function in resp

165 Escherichia coli glutamine synthetase (GS) is a dodecameric assembly of i

166 Here we report that glutamine synthetase (GS) is an endogenous substrate of

167 Glutamine synthetase (GS) is an enzyme localized predomi

168 Glutamine synthetase (GS) is the central enzyme for nitr

169 Glutamine synthetase (GS) is the key enzyme in ammonia a

170 non-native conformations, such as denatured glutamine synthetase (GS) monomers, preventing their agg

171 We generated four individual glutamine synthetase (GS) mutants (DeltaglnA1, DeltaglnA

172 Glutamine synthetase (GS) plays an essential role in met

173 We previously have shown that glutamine synthetase (GS) provides the glutamine needed

174 engsin is an eye lens-specific member of the glutamine synthetase (GS) superfamily.

175 ) show that p300/CBP-mediated acetylation of glutamine synthetase (GS) triggers recognition by the CR

176 T KO mice protein expression and activity of glutamine synthetase (GS) were unaffected, whereas the a

177 by conversion of pericentral vein-juxtaposed glutamine synthetase (GS)(-) hepatocytes into GS(+) hepa

178 Glutamine synthetase (GS), a key enzyme in biological ni

179 s we detected homology between gamma-GCS and glutamine synthetase (GS), allowing these proteins to be

180 To assess the role of glutamine synthetase (GS), an enzyme of central importan

181 he feasibility of inhibiting M. tuberculosis glutamine synthetase (GS), an enzyme that plays a key ro

182 l cell adhesion molecule (EpCAM), K19, CD34, glutamine synthetase (GS), and Ki-67.

183 on were assessed by anti-cytokeratin-7, anti-glutamine synthetase (GS), anti-cytochrome P4502E1 (CYP2

184 in metabolic zonation observed as a lack of glutamine synthetase (GS), Cyp1a2, and Cyp2e1.

185 expressed constitutively in mutants lacking glutamine synthetase (GS), GS is required for repression

186 d up-regulation of beta-catenin targets like glutamine synthetase (GS), leukocyte cell-derived chemot

187 that gamma-GCS is a structural homologue of glutamine synthetase (GS), providing the basis to build

188 zes the adenylylation and deadenylylation of glutamine synthetase (GS), regulating GS activity.

189 s glial fibrillary acidic protein (GFAP) and glutamine synthetase (GS), the bipolar cell marker prote

190 Glutamine synthetase (GS), which catalyzes the productio

191 The enzymatic activity of Bacillus subtilis glutamine synthetase (GS), which catalyzes the synthesis

192 In contrast, glutamine synthetase (GS)--and nuclear beta-catenin--is

193 ractions with the feedback-inhibited form of glutamine synthetase (GS).

194 ylated-beta-catenin (Y654-beta-catenin), and glutamine synthetase (GS).

195 mon property of decreasing total activity of glutamine synthetase (GS).

196 carbamoylphosphate synthetase I (CPS I) and glutamine synthetase (GS).

197 othricin is a potent inhibitor of the enzyme glutamine synthetase (GS).

198 reas they exhibited negligible expression of glutamine synthetase (GS).

199 a) cell immunopositive for both S100beta and glutamine synthetase (GS).

200 vated astrocytes and increased expression of glutamine synthetase (GS).

201 Specifically, coexpression of CD44/Vim and glutamine synthetase (GS)/VGLUT1 reflects glial speciali

202 Glutamine synthetases (GS) are ubiquitous enzymes that p

203 etabolism (glutamate dehydrogenase [GDH] and glutamine synthetase [GS]), axonal damage (SMI 32) and C

204 ivation (tyrosine aminotransferase, TAT, and glutamine synthetase, GS) and transrepression (IL-6).

205 generally mirror the response of cytoplasmic glutamine synthetase (Gs1) transcript abundance to chang

206 chloroplast by a chloroplastic isoenzyme of glutamine synthetase (GS2), the predominant GS isoform i

207 Bacterial glutamine synthetases (GSs) are complex dodecameric olig

208 o experiments showed that feedback-inhibited glutamine synthetase had a significantly reduced ability

209 Feedback-inhibited glutamine synthetase had a significantly reduced ability

210 Although S186F glutamine synthetase has kinetic properties that are sim

211 dition of PS-ODNs against the transcripts of glutamine synthetase I (glnA1) and alanine racemase (alr

212 different glutamine synthetase (GS) enzymes: glutamine synthetase I (GSI) (ORF02151), GSIII-1 (ORF014

213 Glutamine synthetase I (GSI) enzyme activity in Streptom

214 tified Muller cells with vimentin, GFAP, and glutamine synthetase immunoreactivities.

215 A computational calculation of glutamine synthetase immunoreactivity was developed so w

216 Muller cell morphology was different and glutamine synthetase immunoreactivity was reduced in the

217 Glutamine synthetase immunoreactivity was sparse like in

218 -sulfoximine rapidly inhibited extracellular glutamine synthetase in a concentration-dependent manner

219 A deficiency in glutamine synthetase in astrocytes is a possible molecul

220 in their interaction with feedback-inhibited glutamine synthetase in cross-linking experiments.

221 To further explore the role of glutamine synthetase in MTLE we created a novel animal m

222 sed levels of glutamate decarboxylase-65 and glutamine synthetase in PFC; reduced fractional anisotro

223 The amount of glutamine synthetase in the cell and its catalytic activ

224 In western blots, the expression of glutamine synthetase in the hippocampus was 40% lower in

225 the distribution, quantity, and activity of glutamine synthetase in the MTLE hippocampus.

226 an inhibitory effect on the inactivation of glutamine synthetase in the thiol metal-catalyzed oxidat

227 the preferential localization of the enzyme, glutamine synthetase, in pericentral hepatocytes, where

228 s with the 5'UTR of gifA mRNA, which encodes glutamine synthetase inactivating factor (IF)7.

229 ich depends on the ATP-dependent activity of glutamine synthetase, increases for many minutes.

230 The glutamine synthetase inhibitor l-methionine sulfoximine

231 g response to methionine sulfoximine (Msx, a glutamine synthetase inhibitor).

232 nted here demonstrate that rapamycin and the glutamine synthetase inhibitor, methionine sulfoximine (

233 In normal islets, methionine sulfoximine, a glutamine synthetase inhibitor, suppressed insulin relea

234 eport that local application of glutamate or glutamine synthetase inhibitors induces astrocytic relea

235 Although it is possible that glutamine synthetase inhibitors interact with additional

236 this study, we investigated the influence of glutamine synthetase inhibitors on the growth of pathoge

237 the feedback inhibitors necessary to convert glutamine synthetase into its feedback-inhibited form an

238 Finally, we found that a deficiency in glutamine synthetase is an important pathogenic process

239 Glutamine synthetase is central to nitrogen metabolism i

240 We conclude that glutamine synthetase is critical for nitrogen assimilati

241 orted that the glutamate-metabolizing enzyme glutamine synthetase is deficient in the hippocampus in

242 Genetic studies indicate that glutamine synthetase is required for the regulation of T

243 e O. mossambicus OmB cell line revealed that glutamine synthetase is transcriptionally regulated by h

244 One major extracellular protein, the enzyme glutamine synthetase, is of particular interest because

245 Two glutamine synthetase isoforms were found to have differe

246 The assay was used to detect glutamine synthetase isoforms, separated by nondenaturin

247 Phospho-STAT3 colocalized with glutamine synthetase-labeled Muller cells.

248 Glutamine synthetase may be more important for islets th

249 needed to define the cause, but the loss of glutamine synthetase may provide a new focus for therape

250 temporal sclerosis, and that restoration of glutamine synthetase may represent a novel approach to t

251 egulons include those for nitrogen fixation, glutamine synthetase, (methyl)ammonia transport, the reg

252 Mycobacterium tuberculosis glutamine synthetase (MtGS) is a promising target for an

253 We find that pharmacological inhibitors of glutamine synthetase or system A transporters cause an a

254 revealed a 34% increase in the expression of glutamine synthetase (p<0.05) with unchanged metallothio

255 stic foci throughout the hepatic lobule were glutamine synthetase-positive, suggestive of a pericentr

256 methylammonium to gamma-N-methylglutamine by glutamine synthetase precludes its use in assessing conc

257 te plus ammonium, because feedback-inhibited glutamine synthetase (product of glnA) binds to TnrA and

258 biofilm formation and an apparent defect in glutamine synthetase production.

259 nd TnrA proteins is not known, the wild-type glutamine synthetase protein is required for the transdu

260 These results are consistent with the glutamine synthetase protein playing a direct role in re

261 relationship to the more fully characterized glutamine synthetase reaction.

262 feedback-inhibited form of Bacillus subtilis glutamine synthetase regulates the activity of the TnrA

263 odel in which the feedback-inhibited form of glutamine synthetase regulates TnrA activity in vivo.

264 study we show that hyperosmotic induction of glutamine synthetase represents a prominent part of this

265 presence or absence of MSX, an inhibitor of glutamine synthetase, resulting in a block of Glu/Gln sy

266 A homology model of B. subtilis glutamine synthetase revealed that the five mutated amin

267 Immunohistochemistry (alpha-glutamine synthetase) revealed that approximately 95% of

268 r retinaldehyde-binding protein (CRALBP) and glutamine synthetase showed that the GFP-expressing cell

269 Double labeling of CB2R and glutamine synthetase shows that CB2R is restricted to Mu

270 reticulin, alteration of normal perivenular glutamine synthetase staining (absent or diffuse), and v

271 , because a DeltaglnD strain with an altered glutamine synthetase that cannot be adenylylated can gro

272 Missense mutations in glutamine synthetase that constitutively express the Tnr

273 -protein interaction with feedback-inhibited glutamine synthetase that stabilizes GlnR-DNA complexes.

274 he alsS gene), acidifying the growth medium, glutamine synthetase (the glnA gene), and two surfactin

275 how they conjointly modulate the activity of glutamine synthetase, the key enzyme for nitrogen assimi

276 Elevated Mn(II) reduces the sensitivity of glutamine synthetase to feedback inhibitors, and we sugg

277 hanism by which intron 1 positively mediates glutamine synthetase transcription.

278 Glutamine synthetase transmits the nitrogen regulatory s

279 Two different genes encoding glutamine synthetase type I (GSI) and GSIII were identif

280 eterotetrameric sarcosine oxidase (SoxA) and glutamine synthetase type III (GSIII) respectively.

281 hydrolyzing carboxylate-amine ligases of the glutamine synthetase type.

282 nrA at the gltAB promoter was antagonized by glutamine synthetase under certain growth conditions.

283 The level of glutamine synthetase was 2 orders of magnitude higher th

284 S186F glutamine synthetase was defective in its ability to blo

285 A model of B. subtilis glutamine synthetase was derived from a crystal structur

286 the 5' regulatory sequence of O. mossambicus glutamine synthetase was investigated.

287 ns (glnA) in which the catalytic activity of glutamine synthetase was lowered.

288 However, glutamine synthetase was markedly increased in bone marr

289 Loss of glutamine synthetase was particularly pronounced in area

290 Ammonia assimilation gene glnA (glutamine synthetase) was repressed in vivo, while gdhA

291 The levels of glutamine synthetase were reduced in both mutants.

292 Aldehyde dehydrogenase 1 L1 and glutamine synthetase were used as constitutive astrocyti

293 dulin, solute carrier family 1 member 2, and glutamine synthetase) were identified in a phenotype-dep

294 d by expression of immunoreactive Kir4.1 and glutamine synthetase, were closely associated with neuro

295 regulates the AmtB ammonium transporter and glutamine synthetase, which controls the rate of glutama

296 bears a similarity to the mechanism used by glutamine synthetase, which may point to an ancient link

297 rapidly inactivated purified M. tuberculosis glutamine synthetase, which was 100-fold more sensitive

298 A mutation in glutamine synthetase with a phenylalanine replacement at

299 In this study, we inhibited the activity of glutamine synthetase with methionine-sulfoximine (MSO) a

300 ulation of the AmtB ammonium transporter and glutamine synthetase within R. palustris.