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1 P8 can cleave 18:2 and 18:3 acyl groups from glycerolipids.
2 stid are exported for assembly of eukaryotic glycerolipids.
3 ic acid (18:3), are derived from cleavage of glycerolipids.
4 hesis of triacylglycerol and other non-ether glycerolipids.
5 o lipids, a pathway for de novo synthesis of glycerolipids.
6 in the metabolism of endogenous and dietary glycerolipids.
7 incorporation of hydrolyzed fatty acids into glycerolipids.
8 nk the metabolic processes of glycolysis and glycerolipids.
9 as well as numerous sphingolipid classes and glycerolipids.
10 etate and [(14)C]glycerol incorporation into glycerolipids.
11 eir close association with various groups of glycerolipids.
12 golipids (GSLs) with lesser amounts of polar glycerolipids.
13 enic amines, 38% for acylcarnitines, 25% for glycerolipids, 23% for glycerophospholipids, 16% for cho
16 ese data are consistent with a mechanism for glycerolipid acyltransferase catalysis where the invaria
20 samples were (lyso)glycerophospholipids and glycerolipids, although a few free fatty acids, hydroxyc
28 etter understanding of the cancer-associated glycerolipid and sphingolipid metabolism may lead to nov
29 a substantial increase in the percentage of glycerolipid and sphingolipids species containing 24:1 a
31 how plants produce and secrete non-membrane glycerolipids and also how to engineer alternative pathw
32 proteins were enzymes that regulate sugars, glycerolipids and cholesterol itself as well as proteins
35 G3P forms the backbone of TAGs and membrane glycerolipids and it can be dephosphorylated to yield gl
36 Simultaneous detection of high-abundance glycerolipids and low-abundance but not less significant
38 ses involved in the biosynthetic pathways of glycerolipids and sphingolipids and how these enzymes ha
39 LA4 and ALA5 impacts the homeostasis of both glycerolipids and sphingolipids and is important for cel
40 n of membrane structure components including glycerolipids and sphingolipids at early perfusion time
42 pid species, including glycerophospholipids, glycerolipids and sphingolipids, was significantly assoc
44 hat PNPLA3 plays a role in the hydrolysis of glycerolipids and that the I148M substitution causes a l
45 ast revealed that ALA5 can flip a variety of glycerolipids and the sphingolipid sphingomyelin across
46 y shunt fatty acids into de novo synthesized glycerolipids and the transfer of lipids into VLDL, resp
50 closely coordinated with that of sterols and glycerolipids and with other processes that occur in the
52 , mainly belonging to amino acids, peptides, glycerolipids, and nucleic acids, showing a greater hier
53 f [3H]oleic acid (OA) or [3H]glycerol to [3H]glycerolipids, and the turnover of these products in PC1
54 pidomic analysis indicates that both PLs and glycerolipids are qualitatively affected by the mutation
55 with age and cataract support the idea that glycerolipids are selectively oxidized over lipids with
57 data together indicate that Bayberry surface glycerolipids are synthesized by a pathway for TAG synth
60 various ceramides, glycerophospholipids, and glycerolipids, as well as different ion formation mechan
61 es, acyl flux into the eukaryotic pathway of glycerolipid assembly was enhanced at the expense of the
63 d compound classes, including phospholipids, glycerolipids, bacterial lipoglycans and plant glycolipi
64 alyzed aminolysis of arachidonate-containing glycerolipids, because AEA was produced from synthetic (
66 FAD7, SFD1 and SFD2 are involved in plastid glycerolipid biosynthesis and SAR is also compromised in
71 ha, beta, gamma, and delta), indicating that glycerolipid biosynthesis is a conserved host dependency
72 One module contains several elements of the glycerolipid biosynthesis pathway and operates exclusive
73 and lipid homeostasis, probably through the glycerolipid biosynthesis pathway, which may contribute
74 idate phosphatase (PAP) enzymes required for glycerolipid biosynthesis, and also as transcriptional c
75 wild-type hamster GPI restored GPI activity, glycerolipid biosynthesis, and PAP1 activity in GroD1.
76 ere that E. chaffeensis is dependent on host glycerolipid biosynthesis, as an inhibitor of host long-
77 s highly conserved among acyltransferases in glycerolipid biosynthesis, drastically reduced mitochond
78 ), which catalyzes the first step in de novo glycerolipid biosynthesis, is stimulated by casein kinas
79 -chain acyl CoA synthetases, key enzymes for glycerolipid biosynthesis, significantly reduced bacteri
80 interacts with other enzymes involved in ER glycerolipid biosynthesis, suggesting the possibility of
81 e (GPAT) catalyzes the rate-limiting step of glycerolipid biosynthesis, the acylation of glycerol 3-p
82 phosphatase (PAP) enzymes catalyze a step in glycerolipid biosynthesis, the conversion of phosphatida
91 um so that it functions within the cytosolic glycerolipid biosynthetic pathway to esterify C16:0 to t
92 critical roles in trafficking SFAs into the glycerolipid biosynthetic pathway to form saturated phos
95 eficiency appear to include both the loss of glycerolipid building blocks and the accumulation of lip
96 kedly decreased the V(max) of the enzyme for glycerolipids but had only a modest effect on the K(m).
97 tasets revealed that changes in di-saturated glycerolipids, but not other lipid classes, are central
98 indicating reduced synthesis of chloroplast glycerolipids by the prokaryotic pathway of lipid metabo
103 he glycerolipid/free fatty acid (FFA) cycle (glycerolipid cycle), encompassing triglyceride lipolysis
105 es on the thermogenic and signaling roles of glycerolipid cycling in adipose and other tissues and of
106 ea has begun to showcase the central role of glycerolipid cycling mediated thermogenesis and signalin
107 l synthase1 mutant we suggest that a plastid glycerolipid-dependent factor is required in Avr PeX alo
109 he first animal representative of a class of glycerolipid desaturases that have previously been chara
110 adation of phospholipids and biosynthesis of glycerolipid, downregulation of ammonium transport and n
111 g of sphingolipids and increased labeling of glycerolipids dramatically following in vivo labeling wi
113 lso include control of catalytic activity of glycerolipid enzymes by water-soluble precursors, produc
115 tyric acid receptor signaling cascades, plus glycerolipid, fatty acid, and amino acid metabolic pathw
116 FD and corrected increases across a range of glycerolipids, fatty acids, and various lysolipids.
118 gest lipid class, followed by sphingolipids, glycerolipids, fatty acyls, sterol lipids, and prenol li
120 jor divergence pathways for fuel excess, the glycerolipid/fatty acid metabolism and the polyol pathwa
122 To assess the kinetic complexity of the glycerolipid flux network, cultured embryos were incubat
123 on of FFAR1/GPR40 by an antagonist decreased glycerolipid formation, attenuated fatty acid increases
125 ribute substantially to the understanding of glycerolipid fragmentation and showcase the value of vib
133 positional diversity, complex lipids such as glycerolipids, glycerophospholipids, saccharolipids, etc
134 and putative identification of fatty acids, glycerolipids, glycerophospholipids, sphingolipids, and
135 main lipid categories including fatty acyls, glycerolipids, glycerophospholipids, sphingolipids, ster
137 mple, neutral headgroup loss from protonated glycerolipids has been postulated to proceed via an intr
140 categories of lipids: (i) fatty acyls, (ii) glycerolipids, (iii) glycerophospholipids, (iv) cardioli
141 y of the double bond (cis or trans), or, for glycerolipids, (iii) the relative substitution of acyl c
144 ynthesis and accumulation of fatty acids and glycerolipids in islets and protected against beta cell
147 the initial steps of synthesis of its major glycerolipids including those involved in virulence.
148 sion led to higher contents of 18:3-mediated glycerolipids, including galactolipids (monoglactosyldia
149 s incorporated into complex endothelial cell glycerolipids, including monoglycerides, triglycerides,
150 d sphingomyelin, increased with age, whereas glycerolipids, including phosphatidylcholine and two pho
151 ocked the incorporation of [3H]glycerol into glycerolipids, incorporation of [14C]oleate into TG, but
152 the fatty acyl content of various classes of glycerolipids indicated that the Spr2 gene product catal
155 rst step in assembly of membrane and storage glycerolipids is acylation of glycerol-3-phosphate (G3P)
156 In Arabidopsis, a certain proportion of glycerolipids is entirely synthesized in the chloroplast
157 ation between gene expression and changes in glycerolipid levels during the Arabidopsis thaliana resp
158 between the coordination of transcripts and glycerolipid levels in a changing environment and the ef
159 Notably, elevated carnitine, amino acid, and glycerolipid levels in weightlifters suggest energy syst
160 ysis indicates coordinate regulation between glycerolipid metabolism and a broad spectrum of metaboli
162 our work identifies a conserved regulator of glycerolipid metabolism and reveals plasticity in lipid
165 lipin1 and DGATs as intrinsic regulators of glycerolipid metabolism in neurons and indicates that di
166 overy of PDCT is important for understanding glycerolipid metabolism in plants and other organisms, a
170 This may indicate a block in the downstream glycerolipid metabolism pathway in GPD3 overexpression l
173 sylglycerol biosynthesis and associated with glycerolipid metabolism under phosphate-starvation stres
175 te application of T-87 cells for analysis of glycerolipid metabolism, including tests of gene functio
182 kidney tissue fatty acid, phospholipid, and glycerolipid metabolisms prior to and after the onset of
186 hether DGLA could be mobilized from cellular glycerolipids, neutrophils were stimulated with ionophor
191 eased; however, studies on the metabolism of glycerolipids or interactions between different pathways
194 utant, which is defective in the prokaryotic glycerolipid pathway, PDAT1 overexpression enhances TAG
196 , plays important roles in balancing the two glycerolipid pathways and in maintaining lipid homeostas
198 oss all eight lipid categories: fatty acyls, glycerolipids, phosphoglycerolipids, polyketides, prenol
199 nous lipids, including fatty acids, sterols, glycerolipids, phospholipids and glycolipids and can be
200 and biochemical analyses have revealed that glycerolipids play important roles in cell signaling, me
201 een important for evolution of extracellular glycerolipid polymers and adaptation of plants to a terr
205 that GPD1L facilitated the biogenesis of the glycerolipid precursor glycerol-3-phosphate (G3P) from d
206 noninfected D2 mice, this leads to increased glycerolipid production and reduced acylcarnitine produc
208 ple analytical techniques, we determined the glycerolipid profile of P. tricornutum grown with variou
210 of GmPLDa1 resulted in changes in PA levels, glycerolipid profiles, nodule numbers, actin cytoskeleto
217 c acid, mono- and diacylglycerols, and other glycerolipids, some implicated in augmenting insulin sec
218 ailability, this study analyzed the membrane glycerolipid species in soybean root hairs and in roots
219 nces of >600 individual glycerophospholipid, glycerolipid, sphingolipid and sterol lipids between a p
220 lation of glycerophospholipids, fatty acyls, glycerolipids, sphingolipids, prenol lipids, and sterol
221 nization in identifying structurally complex glycerolipid standards as well as species in biodiesel s
223 zes the initial and rate-controlling step in glycerolipid synthesis and aids in partitioning acyl-CoA
227 oxyacetone phosphate (acyl-DHAP) pathway for glycerolipid synthesis is commonly believed to be involv
229 to-oncoprotein c-Fos has an emerging role in glycerolipid synthesis regulation; by interacting with k
230 hosphatase, CNEP-1/CTDNEP1, controls de novo glycerolipid synthesis through lipin to prevent invasion
232 Expression of several genes that regulate glycerolipid synthesis was not changed by GW7647 treatme
233 for the generation of diacylglycerol during glycerolipid synthesis, and exhibits dual functions in t
234 r redox and ATP production, gluconeogenesis, glycerolipid synthesis, and fatty acid oxidation in panc
235 ndrial enzyme catalyzing the initial step in glycerolipid synthesis, are induced during the different
236 rst two steps of the prokaryotic pathway for glycerolipid synthesis, so we investigated whether other
237 acylglycerol mobilization and precursors for glycerolipid synthesis, suggesting that lipid metabolism
252 separate gene, catalyze the initial step in glycerolipid synthesis; in liver, the major isoforms are
253 A comparison of microsomal and peroxisomal glycerolipid synthetic pathways, using D-[3-(3)H, U-(14)
254 PNPLA3 was observed against the three major glycerolipids, TAG, diacylglycerol, and monoacylglycerol
255 f 15 other sphingolipids, phospholipids, and glycerolipids tested, have been termed "sphingosine-depe
257 aine lipids are ether-linked, nonphosphorous glycerolipids that resemble the more commonly known phos
258 ing sphingolipids, glycerophospholipids, and glycerolipids, that differed significantly in abundance
259 in synthesis of triacylglycerol and related glycerolipids, the possible functions of different isoen
260 tracts were treated with 0.1 N KOH to remove glycerolipids, the sphingoid base 1-phosphates were conv
261 acids incorporate into membrane and storage glycerolipids through a series of endoplasmic reticulum
262 he newly synthesized fatty acids first enter glycerolipids through PC acyl editing, largely at the sn
263 enzyme controlling the balanced synthesis of glycerolipids through the glycerol phosphate pathway, en
264 d phospholipase A (pPLA) hydrolyzes membrane glycerolipids to produce monoacyl compounds and free fat
265 , hexosylceramide, ceramide, sphingomyelin), glycerolipids (triglycerides), glycerophospholipids, and
266 Taken together, our work indicates that glycerolipid turnover by Sl-LIP8 is an important early s
267 results indicate that NPC6 promotes membrane glycerolipid turnover to accumulate TAG production in oi
268 the drug inhibited both de novo synthesis of glycerolipids via the glycerol-3-phosphate pathway and t
269 support the hypothesis that the synthesis of glycerolipids via the monoacylglycerol pathway may be hi
271 and ether- species), cholesteryl esters, and glycerolipids were associated with future cardiovascular
272 perimentally that esterified carotenoids and glycerolipids were not removed, indicating a much more s
273 s starvation, 140 molecular species of polar glycerolipids were quantitatively profiled in rosettes a
274 ution of acyl chains typifying mycobacterial glycerolipids wherein unsaturated substituents principal
275 lipids, sphingolipids, free fatty acids, and glycerolipids) which were mapped to their corresponding
277 hermophila resulted the detection of various glycerolipids with an ether bond, indicating reconstitut
278 Certain anaerobic bacteria can synthesize glycerolipids with ether/ester bonds, yet the complexiti