ライフサイエンスコーパス: glycosidase

1 by removal of that sugar with an appropriate glycosidase.

2 amily, DUF2233 functions as a phosphodiester glycosidase.

3 yclitol derivatives was tested against alpha-glycosidase.

4 howed significant inhibition of at least one glycosidase.

5 frame confirmed that this gene encodes an O-glycosidase.

6 enetic complementation and the addition of O-glycosidase.

7 e peptide moieties are released by peptide-N-glycosidase.

8 proteins, including glycosyltransferases and glycosidases.

9 ediated by the consecutive action of several glycosidases.

10 ure-specific catabolism based on a number of glycosidases.

11 se to recognize and modify certain lysosomal glycosidases.

12 as their specific inhibitory behavior toward glycosidases.

13 e-suppression protein that has homology with glycosidases.

14 ere assayed as inhibitors against a panel of glycosidases.

15 eutic agents due to their ability to inhibit glycosidases.

16 man red blood cell (RBC) glycoproteins using glycosidases.

17 njugates could release NO in the presence of glycosidases.

18 n reaction mechanism for both alpha and beta-glycosidases.

19 s their immunogenicity and susceptibility to glycosidases.

20 uential and competitive glycosyltransferases/glycosidases.

21 enoic and benzenoic aglycones than the yeast glycosidases.

22 st glycans as they are modified by bacterial glycosidases.

23 e as acid/base catalyst, which is unique for glycosidases.

24 to the mechanisms accepted for 'retaining' O-glycosidases.

25 oped a rapid electrochemical assay to detect glycosidases.

26 c group that could be easily bioactivated by glycosidases.

27 rides using two glycosidases, multisubstrate glycosidase A (MsgA) and neuraminidase (NanA).

28 These results suggest that glycosidases acting on nonreducing ends digest large amo

29 elivery of nitric oxide (NO), a new class of glycosidase activated NO donors has been developed.

30 The TSP3 structure suggests that the glycosidase active site resides in a cleft at the interf

31 etary compounds and xenobiotics, while other glycosidase activities are involved in the conversion of

32 rtantly, the increased lipase, protease, and glycosidase activities associated with periodontitis gen

33 These new substrates can be used to assay glycosidase activities in a wide pH range (4-11) and wit

34 entral tendency and spatial heterogeneity of glycosidase activities in surficial soil horizons and th

35 The newly discovered DNA-O-glycosidase activities of both enzymes compare favorably

36 iluminescence (ECL)-based detection of RNA N-glycosidase activities of toxins.

37 Other faecal glycosidase activities showed little or no change over a

38 icant effect of crop type was identified and glycosidase activities were 15-39% higher in GG than tho

39 by immunoblotting and selected protease and glycosidase activities.

40 Nitrogen addition significantly increased glycosidase activity (GA) by 13.0%, alpha-1,4-glucosidas

41 Manipulation of beta-glycosidase activity and isoflavone composition can be u

42 ha-synuclein, suggesting that increasing the glycosidase activity can modulate alpha-synuclein proces

43 y of enzymes long believed to possess rRNA N-glycosidase activity directed solely at the universally

44 nant gelonin-LMWP chimera (rG-L) possessed N-glycosidase activity equivalent to that of unmodified re

45 ectrochemiluminescence-based assay for RNA N-glycosidase activity has been modified to permit its use

46 we use this designed switch to modulate beta-glycosidase activity in living cells using indole.

47 Mutational loss of this glycosidase activity in Y. pestis may have contributed t

48 Analysis of glycosidase activity in zebrafish and medaka eggs reveal

49 ble that these are products of an additional glycosidase activity of lyase III, although other mechan

50 Comparing the glycosidase activity of wild-type TSP3 to various point

51 ontact with residues involved in RTA's RNA N-glycosidase activity or induced notable allosteric chang

52 as indicated by a high phosphatase to total glycosidase activity ratio (PHO:GLY), led to 230% higher

53 beta-Glycosidase activity was quantified using p-nitrophenol-

54 Almond beta-glycosidase activity was significantly (p<0.001) reduced

55 SIM beta-glycosidase activity, however, increased, with steaming

56 r domain, soluble Klotho (sKlotho), carrying glycosidase activity, is a humoral factor that regulates

57 ycosidase evolved its highly efficient trans-glycosidase activity.

58 rent families, including a CNG-specific endo-glycosidase activity.

59 ricin A chain, which contains the toxin's N-glycosidase activity.

60 The conformational analysis of glycosidases affords a route to their specific inhibitio

61 he intracellular activities of the lysosomal glycosidases alpha-galactosidase, alpha-mannosidase and

62 Four glycosidases, alpha-glucosidase (AG), beta-glucosidase (

63 to a glycosynthase derived from a retaining glycosidase, an important class of enzymes for carbohydr

64 ximide led to intracellular depletion of the glycosidase and concomitant ablation of asparagine-linke

65 Besides glycosidase and glycanase activities, five new transglyc

66 components are hydrolysed by numerous plant glycosidase and glycanase activities.

67 AlnA and AlnB, members of the pseudouridine glycosidase and haloacid dehalogenase enzyme families, r

68 ng a sensitive approach that combines in-gel glycosidase and protease digestions, permethylation of r

69 esign of synthetic agents that mimic natural glycosidases and address current problems for biological

70 Treatment with various glycosidases and binding to soybean agglutinin indicated

71 dification of the initial oligosaccharide by glycosidases and glycosyltransferases during the glycopr

72 consecutive actions of functionally distinct glycosidases and glycosyltransferases.

73 ra-Golgi localization of sequentially acting glycosidases and glycosyltransferases.

74 ive profiling of the substrate specificities glycosidases and glycosyltransferases.

75 ose (sugar) used as a potential inhibitor of glycosidases and low-calorie carbohydrate sweeteners.

76 Several hydrolytic activities, including glycosidases and proteases, have been previously correla

77 lin A (SIgA) as a substrate of BV-associated glycosidases and proteases.

78 leoside analogues as potential inhibitors of glycosidases and purine nucleoside phosphorylase (PNP) h

79 of the properties and mechanisms of GH1 beta-glycosidases and related enzymes that modulate their act

80 re due to a deficiency of certain hydrolases/glycosidases and subsequent accumulation of nonhydrolyza

81 a large and taxonomically diverse family of glycosidases and transglycosidases that adopt a common b

82 alts, and other ingredients (e.g., PNGase F, glycosidase, and transferase reaction mixtures).

83 rts are also potent inhibitors of intestinal glycosidases, and because of this characteristic, we reg

84 Cell surface biotinylation, sensitivity to glycosidases, and fluorescence microscopy analyses sugge

85 g machineries, such as glycosyltransferases, glycosidases, and nucleotide sugar transporters, but als

86 ese hydrolases comprise an array of lipases, glycosidases, and proteases and thus, they have the pote

87 ested against several commercially available glycosidases, and some of them showed good and selective

88 osed-system assay and uses a dUTP/uracil DNA glycosidase anti-PCR contamination control.

89 Within-plot variances of glycosidases appeared higher in SG than GG but little di

90 nts, Glycoside Hydrolase (GH) Family 1 beta -glycosidases are believed to play important roles in man

91 Glycosidases are essential enzymes that cleave glycoside

92 Soil extracellular glycosidases are significantly affected by nitrogen (N)

93 r glycosylation-the glycosyltransferases and glycosidases-are essential in the development and physio

94 ions contain primarily pectinases, with beta-glycosidase as a secondary activity, which limits their

95 es for their kinetic competency with a given glycosidase as a step to name these enzymes not just for

96 tracts containing recombinant, overexpressed glycosidase as the easily accessible enzyme source.

97 g flavin mononucleotide-binding proteins and glycosidases as examples, we show how the evolutionary p

98 pment of substrate probes for monitoring exo-glycosidases, as well as a range of other enzymes having

99 Common glycosidase assays rely on the hydrolysis of non-natural

100 Additional glycosidase assays were performed to identify potential

101 s/group, 5 samples/pool) and complemented by glycosidase assisted analysis using sialidase and endogl

102 Glycosidase assisted LC-MS-MRM analysis of individual pa

103 the synthesis of fluorogenic substrates for glycosidases based on a sulfonated 7-hydroxycoumarin sca

104 conju-gates as well as for identifying other glycosidases belonging to the new GH98 family.

105 tallographic symmetry) of the 6-phospho-beta-glycosidase, BglT, from T.maritima in native and complex

106 Using a specific glycosidase, both phages penetrate the capsule and infec

107 logous to family 1 glycosyl hydrolases (beta-glycosidases), but the predicted AtSFR2 protein is diver

108 thase mutant of a Thermus thermophilus alpha-glycosidase can react with unnatural glycosides such as

109 conclude that certain proteins annotated as glycosidases can function as transglycosidases.

110 uorinated glycosides are known to resist the glycosidase-catalyzed glycosidic bond cleavage; however,

111 use of food-grade commercial plant cell-wall glycosidases (Celluclast/Novozyme plus Viscozyme) allows

112 ecificity was studied on a panel of relevant glycosidases (cellulases and xylanases) in microtiter pl

113 r and high density of N-linked glycans, with glycosidase digestion abrogating 2G12 cross-reactivity.

114 Glycosidase digestion confirmed the identity of the nonr

115 Glycosidase digestion of the 2 m eluate yielded protein

116 Glycosidase digestion revealed that inhibition of DGK re

117 Glycosidase digestion showed that rat and human corin pr

118 y activated CTL clones combined with various glycosidase digestions and GC-MS linkage analyses.

119 released from DSP following N- and O-linked glycosidase digestions, but these digestions had little

120 cteriophages can digest these capsules using glycosidases displayed on the phage particle.

121 to arginine should destabilize the putative glycosidase domain (KL1) of KL, thereby attenuating prod

122 NET37 mutated at a conserved residue in the glycosidase domain and found that this predicted catalyt

123 taKlotho, a membrane protein with 2 putative glycosidase domains, have increased Cyp7a1 mRNA levels a

124 rovide novel insight into the role of acidic glycosidases during yolk utilization and the evolution o

125 In addition to the K1-specific glycosidase, each K1-5 particle carries a second enzyme

126 ia, the simultaneous characterization of all glycosidases employed by bacteria for the catabolism of

127 porters were often coregulated with adjacent glycosidase-encoding genes.

128 d between a constitutive promoter and a beta-glycosidase-encoding reporter gene (TK1761).

129 We used the glycosidase endoglycosidase H to determine that this dif

130 ide evidence that P2X(7) is sensitive to the glycosidases EndoH and PNGase F and that the human recep

131 beta-Glycosidases enhance wine aroma by releasing volatile ag

132 We present two examples, W33G in a beta-glycosidase enzyme (beta-gly) and W492G in a beta-glucur

133 on the basis of the partition coefficient of glycosidase enzyme activity (Kca).

134 l five iminosugars were studied with various glycosidase enzymes and compared with natural d-gluco-1-

135 Thus, combinations of acid hydrolysis and glycosidase enzymes in almond and flax seed were most ef

136 In vitro screening against several glycosidase enzymes showed highly specific inhibition of

137 ere found to be potent inhibitors of various glycosidase enzymes with Ki and IC50 values in the micro

138 ic dispersal of biofilms by PNAG-hydrolyzing glycosidase enzymes, such as Dispersin B (DspB), is a po

139 ical practice has been the lack of efficient glycosidase enzymes.

140 and subsequently were digested with specific glycosidase enzymes.

141 on glass slides were incubated with selected glycosidase enzymes.

142 herent dynamic framework to understand how a glycosidase evolved its highly efficient trans-glycosida

143 The collective action of BV-associated glycosidases exposes underlying mannose residues of SIgA

144 ized by the classical glycosidases peptide-N-glycosidase F (PNGase F) and endoglycosidase H (Endo H).

145 nline enzyme reactor incorporating peptide-N-glycosidase F (PNGase F) on a monolithic polymer support

146 ies, dual digestion by trypsin and peptide-N-glycosidase F (PNGase F), and analysis by LC-MS/MS.

147 ed with GPVI, deglycosylation with peptide-N-glycosidase F (PNGase F; specific for complex N-linked g

148 A deglycosylation step using Peptide-N-Glycosidase F (PNGaseF) has been introduced in a standar

149 Application of an endoglycosidase, peptide N-glycosidase F (PNGaseF), directly on tissues followed by

150 Moreover, treatment with peptide N-glycosidase F abrogated F240 neutralization, in an isola

151 ith Flavobacterium meningosepticum peptide N-glycosidase F and trypsin, with matrix-assisted laser de

152 N-glycosylation was disrupted using N-glycosidase F and tunicamycin.

153 P-2 is resistant to digestion with peptide N-glycosidase F but is sensitive to release under alkaline

154 Peptide-N-glycosidase F digestion of solubilized hKOR or incubatio

155 ted species and was converted to 27 kDa by N-glycosidase F or tunicamycin treatments.

156 Treatment with peptide-N-glycosidase F reduced the size of the mammalian cell- an

157 e glycosylated, and treatment with peptide N-glycosidase F reduces the apparent molecular mass on SDS

158 Treatment of heart lysates with peptide-N-glycosidase F revealed that while giant obscurin-B local

159 beta-N-acetylglucosaminidase H and peptide:N-glycosidase F sensitivity assays on CDKAL1 constructs ca

160 t of kidney membrane proteins with peptide N-glycosidase F showed that GLUT9 and GLUT9DeltaN are expr

161 Etanercept was first treated with peptide N-glycosidase F to release the N-glycans.

162 bound fractions, and treated with peptide: N-glycosidase F to remove N-linked glycans.

163 oproteins and molecular mass after peptide-N-glycosidase F treatment was 38 and 45 kDa, respectively.

164 Using pulse-chase radiolabeling, peptide-N-glycosidase F treatment, lectin pulldowns, and exoglycos

165 N-linked carbohydrate was removed by using N-glycosidase F was markedly less effective in protecting

166 uronic acid as well as proteoglycan N-linked glycosidase F(PNGaseF)- and sialidase A-treated human er

167 tein-tagged mCLCA6 with PNGase F (peptide: N-glycosidase F) to remove N-linked glycosyl groups shows

168 Peptide N-glycosidase F, but not endoglycosidase H, digestion conv

169 y 120 kDa following treatment with peptide:N-glycosidase F, consistent with N-glycosylation being the

170 Digestion with N-glycosidase F, endoglycosidase H and lectin blotting did

171 y released from glycoproteins with peptide N-glycosidase F, followed by purification with graphitized

172 e cultured medium, and upon treatment with N-glycosidase F, the molecular mass was lowered by approxi

173 mass spectrometry on purified and peptide N-glycosidase F-deglycosylated CD36 and also by comparing

174 ately 160 kDa after treatment with peptide N-glycosidase F.

175 pproaches, including use of either peptide:N-glycosidases F and A (PNGase F and A) or anhydrous hydra

176 g sequential endoglycosidase H and peptide:N-glycosidase-F digestions.

177 of the full-length homotrimer with peptide N-glycosidase-F under native conditions abolished recognit

178 NET37, a member of glycosidase family 31, is highly expressed in mouse skel

179 select agent toxin and a member of the RNA N-glycosidase family of medically important plant and bact

180 h trans and then medial glycosyltransferases/glycosidases found in the scattered, nascent Golgi.

181 The single-domain GH11 glycosidase from Bacillus circulans (BCX) is involved in

182 mparable to profiling by PNGase F (peptide N-glycosidase from Flavobacterium meningosepticum) digesti

183 owed by an enzymatic treatment with the beta-glycosidase from Periplaneta americana allowed the effic

184 This study investigated the role of beta-glycosidase from processed soy-ingredient mixture (SIM)

185 able insight into the mechanism of a novel N-glycosidase from the structural point of view, which in

186 Removal of the oligosaccharides by glycosidase from wild-type carboxylase or by elimination

187 er homology to the sequences of several beta-glycosidases from thermophilic archea and bacteria.

188 iously unreported sites that are crucial for glycosidase function.

189 Glycosidase gel shift analysis suggested that K(v)2.1, K

190 ed unusually frequent mutation of the beta-D-glycosidase gene (lacS) of a shuttle plasmid (pJlacS) pr

191 Here we report two bacterial glycosidase gene families that provide enzymes capable o

192 on OC cell lines targeted by mAb-A4, we used glycosidases, glycan microarray, siRNA, and advanced hig

193 stence of monofunctional transpeptidases and glycosidases (glycoside hydrolases), trimeric peptide cr

194 The presence of glycosidases have been widely used to detect pathogens,

195 ion effects on spatial distributions of soil glycosidases have not been well addressed.

196 By protease mapping we show that its glycosidase homology domain is located in the lumen of t

197 elopment of FRET-quenched substrates for exo-glycosidases, however, has been hindered by their constr

198 ot disruptable by a variety of exo- and endo-glycosidases, implying recognition of a non-glycan epito

199 761, a gene that encodes a nonessential beta-glycosidase in Thermococcus kodakaraensis.

200 tudy investigates the collateral activity of glycosidases in commercial pectinase preparations, and t

201 rate Golgi-resident glycosyltransferases and glycosidases in distinct Golgi compartments are poorly u

202 Extracellular glycosidases in soil, produced by microorganisms, act as

203 l gut and become activated by bacterial beta-glycosidases in the distal gut.

204 lases and recently discovered apoplastic exo-glycosidases in the hydrolytic modification of matrix xy

205 chemical properties, and function of several glycosidases in zebrafish eggs, embryos, and adult tissu

206 f their binding affinities toward a panel of glycosidases including the Jack Bean alpha-mannosidase (

207 ymes, such as lipoxygenases, peroxidases and glycosidases, including myrosinase in broccoli, is key t

208 Endogenous glycosidases, including neuraminidase 1 (Neu1), neuramin

209 e detected with other adenine-specific RNA N-glycosidases, including Ricinus communis agglutinin (RCA

210 ced to lower Mr bands by neuraminidase and O-glycosidase, indicating that the hKOR contains O-linked

211 ynthesized molecules have been evaluated for glycosidase inhibition against 6 commercially available

212 Glycosidase inhibition and lectin deficiencies increased

213 A definitive side-by-side comparison of the glycosidase inhibition of a panel of 13 glycosidases sho

214 , and some of them showed good and selective glycosidase inhibition.

215 iminosugars have been recently explored for glycosidase inhibition.

216 the structural features and their effect on glycosidase inhibitions.

217 active approach to the rapid optimization of glycosidase inhibitor potency and pharmacokinetic behavi

218 ion to the concise preparation of the potent glycosidase inhibitor, (-)-swainsonine.

219 rry 1-deoxynojirimycin (DNJ), a potent alpha-glycosidase inhibitor, has therapeutic potency in the su

220 pseudoviruses produced in the presence of a glycosidase inhibitor, kifunensine.

221 labeled thiosugar was prepared as a putative glycosidase inhibitor.

222 its d-enantiomer, l-NBDNJ does not act as a glycosidase inhibitor.

223 lipids, and biguanides, sulfonylureas, alpha-glycosidase inhibitors [AGIs], and insulin adjusted for

224 The importance of glycosidase inhibitors and especially the bicyclic molec

225 -throughput assays for identifying retaining glycosidase inhibitors by FluoPol-ABPP on cell extracts

226 will inform the design of new generations of glycosidase inhibitors with restricted side chains that

227 yl substituted aminocyclitols were tested as glycosidase inhibitors.

228 itive patterns of inhibition for a number of glycosidase inhibitors.

229 ased iminocyclitols are a promising class of glycosidase inhibitors.

230 of pseudoviruses in the presence of various glycosidase inhibitors; and (iii) the growth of pseudovi

231 xhibiting outstanding biological activity as glycosidases inhibitors.

232 The glycosidase inhibitory activities of all five iminosugar

233 addition of various glycosyltransferases and glycosidases into nascent, golgin-enriched structures af

234 atalytic glutamate residues conserved across glycosidases into sKlotho enhanced its glucuronidase act

235 The low basal concentration of the glycosidase is believed to coordinate the glycan cleavag

236 pecific enzymes like proteases, esterases or glycosidases is often higher in tumor cells than in norm

237 ase (beta-gal), one of the typical lysosomal glycosidases, is reported to be a vital biomarker overex

238 of five distinct protein domains, including glycosidase, leucine-rich repeat, hybrid Ig, carbohydrat

239 grade glycans into monosaccharides using two glycosidases, multisubstrate glycosidase A (MsgA) and ne

240 the long held view that potent inhibitors of glycosidases must mimic an oxacarbenium ion like transit

241 The ability of the O-glycosidase mutant to cleave this glycan structure was r

242 rus receptor 1 (XPR1), myogenesis regulating glycosidase (MYORG), platelet-derived growth factor B (P

243 fin granule membranes in the presence of the glycosidase N-glycanase shifted the apparent molecular w

244 borative activities of glycosyltransferases, glycosidases, nucleotide-sugar transporters, sulfotransf

245 are efficiently turned over by the human exo-glycosidase O-GlcNAcase (OGA).

246 ce protein with sequence similarity to the O-glycosidase of Bifidobacterium longum.

247 in is divergent from all other family 1 beta-glycosidases of Arabidopsis, showing closer homology to

248 dies, respectively, as they do not carry out glycosidase or glycosyl transferase reactions, and they

249 l applications, but the use of either enzyme glycosidases or small-molecule catalysts in biological s

250 d insensitive to physiological temperatures, glycosidases, or host cell degradation.

251 ly N-glycans not recognized by the classical glycosidases peptide-N-glycosidase F (PNGase F) and endo

252 After incubation with beta-glycosidase, percentage of aglycone (total aglycone/tota

253 processing alpha1,2-mannosidases (family 47 glycosidases) play critical roles in the maturation of A

254 reciated that some bacterial species express glycosidases, previous studies have not considered wheth

255 Glycosidases produced by some normal colonic bacteria an

256 Remarkably, sequential glycosidase-protease digests led to a complete or near-c

257 Using glycosidases, proteases, Western blotting, confocal micr

258 ding cleft topologies of the other family 47 glycosidases provides a framework for understanding the

259 ugh the biological significance of the DNA-O-glycosidase reactions is not known, the evolution of new

260 of electrochemically inactive substrates to glycosidases releases glucose, which can be measured eas

261 Apiosidases are glycosidases relevant for aroma development during ferme

262 idues, and binding to gp120 was abrogated by glycosidase removal of high-mannose glycans and terminal

263 pounds, however, also target other retaining glycosidases, rendering generation and interpretation of

264 and celery were used to test the effects of glycosidase-rich foods and thermal processing on the sta

265 ur method to map the activity of millions of glycosidase sequence variants.

266 the glycosidase inhibition of a panel of 13 glycosidases showed that 8 of the 10 stereoisomers showe

267 ferent enzymatic digestion procedures (i.e., glycosidase, sialidase, and protease) was systematically

268 Knowledge of lectin and glycosidase specificities is fundamental to the study of

269 determination and description of lectin and glycosidase specificities.

270 The anti-aging hormone klotho and other glycosidases stimulate TRPV5-dependent Ca(2+) uptake.

271 ce that S. pneumoniae expresses a secreted O-glycosidase that cleaves galactose beta1-3 N-acetylgalac

272 some-inactivating protein (RIP) and an RNA N-glycosidase that removes specific purine residues from t

273 active HA degradation by treatment with beta-glycosidases that act at the nonreducing end.

274 Using specific glycosidases that convert A and B glycans to the underly

275 osome inactivating proteins (RIPs) are RNA N-glycosidases that depurinate a specific adenine residue

276 proteins (RIPs) from angiosperms are rRNA N-glycosidases that have been proposed as defence proteins

277 S. pneumoniae is known to encode a number of glycosidases that may modify these glycoconjugates in vi

278 to the upregulation of CsBGLU18 (an ABA beta-glycosidase) that cleaves ABAGE.

279 Glycosynthases, which are mutant glycosidases, that can readily form glycosidic linkages

280 While Rpf proteins are clearly peptidoglycan glycosidases, the mechanism and role of Rpf in mediating

281 u; however, in contrast to proteases and exo-glycosidases, there are no simple guidelines for the des

282 an sequentially be decaged by an appropriate glycosidase to liberate a terminal beta-GlcNAc moiety, w

283 type Kv1.2 channels on the cell surface with glycosidase to remove sialic acids also results in the f

284 odel glycoconjugate demonstrated that this O-glycosidase, together with the neuraminidase NanA, is re

285 differentiated from a larger selection of N-glycosidase toxins than was previously examined.

286 Endoglycosidase H and peptide N-glycosidase treatment and cell surface immunoprecipitati

287 Glycosidase treatment that removed O-linked sugars reduc

288 ter their O-glycans have been removed with O-glycosidase treatment, thus revealing this post-translat

289 ion site, which is reduced to 26 kDa after N-glycosidase treatment.

290 e can function as a protease-resistant major glycosidase under the conditions of stomach and intestin

291 g Env production, followed by treatment with glycosidases under conditions that preserve Env trimer i

292 H group that, in all other known families of glycosidase using this mechanism, is an aspartate or glu

293 The transiently expressed recombinant human glycosidase was subject to rapid intracellular turnover

294 mannose phosphorylation of several lysosomal glycosidases was observed in morphant lysates, consisten

295 Five different glycosidases were detected rapidly within 1 h using disp

296 is rather than the Glu or Asp found in other glycosidases were not apparent.

297 N-glycans can be released by glycosidases, whereas O-glycans are often cleaved by che

298 uding humans, comprising two-sub families of glycosidases which all cleave the chitobiose core of N-l

299 repurposed glucose meters to rapidly detect glycosidases, which in turn could be useful to report th

300 of phenotypes in mutants defective for other glycosidases, which trim Gal or Fuc, suggests that XYL1