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1 nd the type I dockerin module from the Cel9D glycoside hydrolase.
2 ses, glycosyltransferases, and one family 16 glycoside hydrolase.
3 /Trp chains appear almost exclusively in the glycoside hydrolases.
4 ycans, S. pneumoniae deploys a wide array of glycoside hydrolases.
5 hose found in both family 127 and 129 of the glycoside hydrolases.
6 or for the detection and characterization of glycoside hydrolases.
7 gically and industrially important family of glycoside hydrolases.
8 (CE4s) and a domain structurally similar to glycoside hydrolases.
9 harides, thereby enhancing the efficiency of glycoside hydrolases.
10 etylated to be protected from degradation by glycoside hydrolases.
11 de that the GH61 proteins are unlikely to be glycoside hydrolases.
12 uding an unusual repertoire of extracellular glycoside hydrolases.
13 arrel structure, which is common to family 1 glycoside hydrolases.
14 ide hydrolases (GH), including 32 family GH2 glycoside hydrolases.
15 volved in binding and import of glycans, and glycoside hydrolases.
16 like system to control production of several glycoside hydrolases.
17 t indicates that it is a member of family 64 glycoside hydrolases.
18 talytic motif of families 16 and 7 retaining glycoside hydrolases.
19 omologous and functionally diverse family of glycoside hydrolases.
20 was proposed that these enzymes function as glycoside hydrolases.
21 substrate, we identified and characterized a glycoside hydrolase 109 (GH109) that is active on blood
23 ve proteomics study in which we identify two glycoside hydrolase 13 family enzymes, and three ABC tra
25 glycanases are part of the large and diverse glycoside hydrolase 16 (GH16) family and are often lipop
26 ns (ZgAgaC) that is distantly related to the glycoside hydrolase 16 (GH16) family beta-agarases and b
30 ype A-antigen, along with a new subfamily of glycoside hydrolase 31 (GH31) that specifically cleaves
31 62 family enzyme was very similar to that of glycoside hydrolase 43 family enzymes, and the catalytic
32 tive sugar-binding pockets characteristic of glycoside hydrolase 70 (GH70) glucansucrases that are kn
33 terization of small-molecule activators of a glycoside hydrolase (a bacterial O-GlcNAc hydrolase).
34 activity in vivo, and could also be used for glycoside hydrolase activation in many industrial proces
37 alyzing an MSI data set of a high-throughput glycoside hydrolase activity screen comprising 384 sampl
38 his array for detecting exo- and endo-acting glycoside hydrolase activity using commercial enzymes, a
39 the GhCTL group are assigned to family GH19 glycoside hydrolases along with numerous authentic chiti
42 paradigm of protein complex assembly beyond glycoside hydrolase and carbohydrate active enzymes, and
44 12 protein, PF13204 and PF12904, as putative glycoside hydrolase and glycoside hydrolase-associated C
46 reveal the first instance of an FMN-binding glycoside hydrolase and suggest a potential link between
47 s are also present in several other R. albus glycoside hydrolases and are phylogentically distinct fr
48 drate-binding modules (CBMs) are appended to glycoside hydrolases and can contribute to the degradati
50 ption, biochemical analysis of all predicted glycoside hydrolases and carbohydrate-binding proteins,
51 ure of GTase closely resembles the family 13 glycoside hydrolases and conservation of key catalytic r
52 ferent types of carbohydrate-active enzymes, glycoside hydrolases and glycosyltransferases, have conv
55 e-degrading and -modifying enzymes including glycoside hydrolases and lytic polysaccharide monooxygen
56 s interaction with cohesin modules, and only glycoside hydrolases and other carbohydrate active enzym
58 nisms have evolved elaborate sets of modular glycoside hydrolases and similar enzymes aimed at the de
59 accharide utilization loci encoding numerous glycoside hydrolases, and by signaling the host to produ
60 n proteins such as polysaccharide synthases, glycoside hydrolases, and carbohydrate-binding modules.
61 c of the B(2) (or theme D) group of family 9 glycoside hydrolases, and Cel48A is structurally similar
67 lex called a cellulosome, which co-ordinates glycoside hydrolase assembly, bacterial adhesion to subs
68 PF12904, as putative glycoside hydrolase and glycoside hydrolase-associated C-terminal domain respect
70 -binding modules (CBMs) derived from modular glycoside hydrolases belonging to families 2a, 6, and 29
72 ereal type family inhibitors (CTIs) bound to glycoside hydrolases but is structurally analogous to bi
73 metagenomics provide access to libraries of glycoside hydrolases but the biochemical characterizatio
74 s to show that among the dozens of different glycoside hydrolases C. phytofermentans secretes on cell
76 ay, the alpha-galactosidase Aga (a family 36 glycoside hydrolase), can cleave alpha-(1->3)-linked gal
77 D is a modular enzyme containing a family 30 glycoside hydrolase catalytic domain and an attached car
78 glucanase comprising an N-terminal family 81 glycoside hydrolase catalytic module, an internal family
79 s of specific gene families belonging to the glycoside hydrolase category reflected contrasting ecolo
83 n, and loop flexibility between the family 7 glycoside hydrolase cellobiohydrolases from H. irregular
84 me, there are fundamental differences in the glycoside hydrolase content that appear to be diet drive
87 structural data reveal that PlyCA contains a glycoside hydrolase domain in addition to the previously
88 known multicatalytic enzymes contain several glycoside hydrolase domains and one or more carbohydrate
90 activity, suggesting that T6S peptidoglycan glycoside hydrolase effector families may comprise signi
92 propose a scheme of sequential action by the glycoside hydrolases encoded by the beta-mannan PUL and
94 hat they are beta-porphyranases belonging to glycoside hydrolase families 16 and 86, respectively.
102 identified beetle myrosinase belongs to the glycoside hydrolase family 1 and has up to 76% sequence
103 % to 92% amino acid identity with members of glycoside hydrolase family 1, including their catalytic
112 The XTH gene products compose a subfamily of glycoside hydrolase family 16 (GH16), which also compris
113 two distant bacterial phyla, which belong to glycoside hydrolase family 16 and cleave the beta-1,4 li
116 lar protein that is predicted to contain two glycoside hydrolase family 18 (GH18) catalytic domains,
117 oh_4555 (ChiA), a 168.9-kDa protein with two glycoside hydrolase family 18 (GH18) domains, was target
118 gnificant similarity to other members of the glycoside hydrolase family 23 (GH23), such as the g-type
120 d drug design efforts on alpha-GAL and other glycoside hydrolase family 27 enzymes by developing liga
122 physiological roles of the four C. japonicus glycoside hydrolase family 3 (GH3) members on diverse be
125 rase and isomaltase) that both belong to the glycoside hydrolase family 31 (GH31) and differ in subst
127 lgi alpha-mannosidase II (GMII), a member of glycoside hydrolase family 38, cleaves two mannosyl resi
129 n be differentially modulated in vitro using glycoside hydrolase family 43 and family 51 arabinofuran
130 characterization, and kinetic analysis of a glycoside hydrolase family 43 beta-xylosidase (Xyl43A) f
135 Carbohydrate-Active Enzyme (CAZy) database, glycoside hydrolase family 5 (GH5) is a large family wit
140 45 kDa, 413-amino acid protein belonging to glycoside hydrolase family 5, has been determined by mul
141 ng forces underlying specificity patterns in glycoside hydrolase family 5, we quantitatively screened
143 Here we present the crystal structure of a glycoside hydrolase family 50 exo-beta-agarase, Aga50D,
145 hydrate binding module family 33 (CBM33) and glycoside hydrolase family 61 (GH61) are likely to play
147 -L-arabinofuranosidase, which belongs to the glycoside hydrolase family 62 (GH62), hydrolyzes arabino
148 saccharide glucanotransferase belongs to the glycoside hydrolase family 66 and catalyzes an intramole
150 and O-glycosylation on a model, multimodular glycoside hydrolase family 7 cellobiohydrolase (Cel7A),
152 H. jecorina Cel7A, cellobiohydrolase I, from glycoside hydrolase family 7, is the workhorse enzyme of
153 3-GBD-CD2 is a transglucosylase belonging to glycoside hydrolase family 70 (GH70) that catalyzes the
155 Microbial alpha-glucans produced by GH70 (glycoside hydrolase family 70) glucansucrases are gainin
159 32 carbohydrate binding module (CBM32) of a glycoside hydrolase family 8 chitosanase from Paenibacil
160 fringens unsaturated glucuronyl hydrolase of glycoside hydrolase family 88 in the CAZy classification
163 es and endo-alpha-1,2-mannanases, members of glycoside hydrolase family 99 (GH99), are interesting ta
164 s highest overall structural similarity to a glycoside hydrolase family associated with peptidoglycan
168 snapshots along the reaction coordinate of a glycoside hydrolase family GH29 alpha-L-fucosidase unvei
172 GYxYP-containing proteins constitute a novel glycoside hydrolase family of as yet unknown specificity
176 d function necessitate the creation of a new glycoside hydrolase family, GH166, whose structural and
178 We propose that the increased affinity of glycoside hydrolases for polysaccharides, through the sy
183 Expression profiles of most endo-acting glycoside hydrolase genes correlated well with their rep
184 biochemical properties, although exo-acting glycoside hydrolase genes displayed less specific expres
185 lucose generally repressed expression of all glycoside hydrolase genes, other sugars induced or repre
186 Remarkably, some beta-glucosidases of the glycoside hydrolase (GH) 1 family are tolerant to or eve
190 lobal MS data, revealing ABP selectivity for glycoside hydrolase (GH) enzymes, in addition to a large
193 ng protein sequence space has revealed a new glycoside hydrolase (GH) family (GH164) of putative mann
195 ed carbohydrate active genes encode a unique glycoside hydrolase (GH) family 10 endoxylanase (BiXyn10
198 the pK(a) values of titratable residues of a glycoside hydrolase (GH) family 6 cellobiohydrolase (Cel
199 enzymes have 97% identity and belong to the glycoside hydrolase (GH) family GH36 for which few struc
201 ermite hindgut was observed when we compared glycoside hydrolase (GH) profile of buffalo rumen metage
203 h, produces an extensive array of exo-acting glycoside hydrolases (GH), including 32 family GH2 glyco
206 r2455) were identified that encode family 39 glycoside hydrolases (GH39s), and have conserved structu
208 f EXPB1 domain 1 resembles that of family-45 glycoside hydrolase (GH45), with conservation of most of
210 PMOs were incorrectly annotated as family 61 glycoside hydrolases (GH61s) or family 33 carbohydrate-b
212 hy3367 gene, which encodes the sole family 9 glycoside hydrolase (GH9) in the C. phytofermentans geno
215 The independent activities of PUL-encoded glycoside hydrolases (GHs) and surface glycan-binding pr
222 comprised of glycosylated linkers connecting glycoside hydrolases (GHs) to carbohydrate-binding modul
225 by mixtures of processive and nonprocessive glycoside hydrolases (GHs), which exhibit synergistic ac
230 ed action of a variety of enzymes, including glycoside hydrolases, glycoside phosphorylases, and tran
231 ing is controlled by the equilibrium between glycoside hydrolases, glycosyltransferases, and transgly
233 filtrate was identified as the only family 7 glycoside hydrolase in the genome, which consists of a s
234 alysis revealed the existence of 29 putative glycoside hydrolases in addition to the previously ident
236 linear alpha-Gal epitope can be processed by glycoside hydrolases in family GH110, whereas the presen
239 ing the activity of endogenous levels of any glycoside hydrolases, including GCase, has proven proble
240 ean, MGIIa_P contained higher proportions of glycoside hydrolases, indicating the ability of MGIIa_P
242 highly conserved, significant differences in glycoside hydrolase inventories and numbers of carbohydr
243 hydrolase domains from Sph3, an A. fumigatus glycoside hydrolase involved in GAG synthesis, and PelA,
244 -mannosidase (MANEA) is the sole endo-acting glycoside hydrolase involved in N-glycan trimming and is
245 enes, in particular a strong upregulation of glycoside hydrolases involved in mannan degradation.
246 The degradation of the plant cell wall by glycoside hydrolases is central to environmentally susta
247 bohydrate-binding modules (CBM) of microbial glycoside hydrolases is central to natural and efficient
248 The function of CBMs appended to exo-acting glycoside hydrolases is unclear because their typical en
249 rrespondence to other family 5 and family 10 glycoside hydrolases, lie inside this cleft on the C-ter
250 urated uronic acid, is removed from AGP by a glycoside hydrolase located in family GH105, producing t
252 ultifunctional enzyme mixtures consisting of glycoside hydrolases, lytic polysaccharide mono-oxygenas
253 we propose a new variation of the retaining glycoside hydrolase mechanism wherein the intervening wa
254 t A.actinomycetemcomitans produces a soluble glycoside hydrolase named dispersin B, which degrades PG
255 thetaiotaomicron contains a large number of glycoside hydrolases not represented in our own proteome
256 subfamily would rather work in synergy with glycoside hydrolases of the GH92 and GH18 families in th
258 drate binding modules (CBMs) of cell surface glycoside hydrolases often drive binding to the target s
259 he nature of such a reaction intermediate in glycoside hydrolases operating via substrate-assisted ca
260 nt processes, such as bioprospecting for new glycoside hydrolases or identifying novel energy sources
261 In nature, many microbes secrete mixtures of glycoside hydrolases, oxidoreductases, and accessory enz
262 endent enzymes (EC 1.14.99.53-56) that, with glycoside hydrolases, participate in the degradation of
264 d to analyze both endo-acting and exo-acting glycoside hydrolases, polysaccharide lyases, carbohydrat
266 membrane polysaccharide-binding proteins and glycoside hydrolases, prioritized the consumption of lib
267 genetic studies have shown that the putative glycoside hydrolase PslG is essential for Psl biosynthes
268 residues similar to those of other family 39 glycoside hydrolases, PslG(31-442) exhibits a unique 32-
269 on a polysaccharide if the producer-derived glycoside hydrolase, responsible for PBP generation, is
271 at from MvX56, a module found in a family 33 glycoside hydrolase sialidase from Micromonospora viridi
274 mulated 284 putative fucoidanases, including glycoside hydrolases, sulfatases and carbohydrate estera
276 c onto proteins and O-GlcNAcase (OGA) is the glycoside hydrolase that acts to remove O-GlcNAc from pr
277 , we show that recombinant Ega3 is an active glycoside hydrolase that disrupts GAG-dependent A. fumig
278 ate binding modules (CBMs) are components of glycoside hydrolases that attack generally inaccessible
281 the relatively high cost of enzymes such as glycoside hydrolases that catalyze cellulose hydrolysis
282 Hyaluronidases are a family of endolytic glycoside hydrolases that cleave the beta1-4 linkage bet
283 oned, expressed and characterized all of the glycoside hydrolases that contain a dockerin module.
284 indicates that they are members of family 16 glycoside hydrolases that have significant sequence iden
286 analysis reveals approximately 130 predicted glycoside hydrolases that target the major structural an
288 d in this enzyme and those of other family 9 glycoside hydrolases, the active site of GH9_CbhA is blo
289 domain with significant similarity to known glycoside hydrolases, the C-terminal domain has a beta-s
290 ative protein-coding genes, of which 103 are glycoside hydrolases, the highest detected number in clu
292 ofermentans has a repertoire of 108 putative glycoside hydrolases to break down cellulose and hemicel
293 ulases, hemicellulases, xylanases, and other glycoside hydrolases to facilitate the degradation of hi
294 idomain extracellular and S-layer-associated glycoside hydrolases to process the carbohydrate content
295 functional transpeptidases and glycosidases (glycoside hydrolases), trimeric peptide crosslinks, cell
296 hypothetical protein with low similarity to glycoside hydrolases was shown to possess endoxylanase a
297 larity to any of the 97 existing families of glycoside hydrolases, we have proposed to assign this un
299 modules (CBMs) are ubiquitous components of glycoside hydrolases, which degrade polysaccharides in n
300 er feature differs from the vast majority of glycoside hydrolases, which use a carboxylic acid, highl