ライフサイエンスコーパス: glycosidic bond

1 can retain the anomeric configuration of the glycosidic bond.

2 uite indirect because of the lability of the glycosidic bond.

3 cid catalyst responsible for cleavage of the glycosidic bond.

4 ovements that occur during cleavage of the N-glycosidic bond.

5 non-paired adenosines and cleavage of the N-glycosidic bond.

6 to serine/threonine residues via an O-linked glycosidic bond.

7 ne closer to the cleavable substrate beta1,4-glycosidic bond.

8 rogen bond was directly across from the dCTP glycosidic bond.

9 Gal attached to the O-linked GlcNAc by a 1-3 glycosidic bond.

10 the anomeric-to-anomeric alpha, beta-1",11'-glycosidic bond.

11 involves the breakage and re-formation of a glycosidic bond.

12 was in the syn(chi)() conformation about the glycosidic bond.

13 substrate show events after cleavage of the glycosidic bond.

14 t base by catalyzing the hydrolysis of the N-glycosidic bond.

15 enzyme are induced by the hydrolysis of the glycosidic bond.

16 products from DEA-mediated cleavage at the N-glycosidic bond.

17 sidue for assisting in the hydrolysis of the glycosidic bond.

18 both bind in an anti conformation about the glycosidic bond.

19 e ligands at several positions including the glycosidic bond.

20 e their excision through hydrolysis of the N-glycosidic bond.

21 Y active site modulate the lability of the N-glycosidic bond.

22 of the l-histidine through a hydrolyzable N-glycosidic bond.

23 sidue and thereby facilitate cleavage of the glycosidic bond.

24 lting in a Schiff base intermediate at the N-glycosidic bond.

25 ell characterized in cells due to its labile glycosidic bond.

26 protein Ser or Thr residues via an O-linked glycosidic bond.

27 the hyaluronic acid polymer at the beta-1,4 glycosidic bond.

28 talysis to achieve selective cleavage of the glycosidic bond.

29 oxygen for subsequent oxidative cleavage of glycosidic bonds.

30 accharide residues covalently linked through glycosidic bonds.

31 es may utilize in catalyzing the cleavage of glycosidic bonds.

32 ternatively linked by alpha-1,3 and beta-1,4 glycosidic bonds.

33 lly compatible with the presence of multiple glycosidic bonds.

34 (13)C coupling constants measured across the glycosidic bonds.

35 es a cyclic beta-glucan lacking beta-(1-->6)-glycosidic bonds.

36 nose units (D-GalpA) linked by alpha-(1-->4) glycosidic bonds.

37 t rotamer orientations about their beta(1,6) glycosidic bonds.

38 control selectivity during the formation of glycosidic bonds.

39 ote the stereoselective formation of 1,2-cis-glycosidic bonds.

40 s of enzymes responsible for the cleavage of glycosidic bonds.

41 , that are linked by amide, ether, ester, or glycosidic bonds.

42 the LPMO mechanism for oxidative cleavage of glycosidic bonds.

43 Due to the lability of the glycosidic bond, 8-nitrodG cannot be incorporated into o

44 f other dipterans in the linkage at a single glycosidic bond, a distinction with significant structur

45 risaccharide is presented in which all three glycosidic bonds, a 1,2-cis-equatorial, a 1,2-trans-axia

46 Hence, the glycosidic bonds act as mechanical levers, driving the c

47 The inherent flexibility around their glycosidic bonds allows them to easily assume a variety

48 om the formal hydrolysis of the nucleotides' glycosidic bonds, along with a variety of oxidized abasi

49 trong hyperconjugation between the elongated glycosidic bond and both of the C2'-H2' bonds.

50 MCDTs for alkali metal ion dissociation and glycosidic bond and cross-ring cleavages were resolved f

51 tation of the nicotinamide ring around the N-glycosidic bond and displacement of C1 of 6PG, facilitat

52 from the double-stranded DNA, cleaves the N-glycosidic bond and leaves the C1' hydrolyzed abasic sug

53 ows the phosphate group poised to attack the glycosidic bond and promote phosphorolysis.

54 formation from 1 involves rotation about the glycosidic bond and that the rate constant for this proc

55 on-canonical pair, with one G syn around the glycosidic bond and the other anti.

56 t base excision may occur by cleavage of the glycosidic bond and then attachment of Lys249.

57 in a high number of distance restraints per glycosidic bond and, consequently, a well-defined struct

58 fferences in the hydrolytic stability of the glycosidic bonds and in the susceptibility of monosaccha

59 ing cycle, which likely includes energy from glycosidic bonds and other sources.

60 degrees of conformational change around the glycosidic bonds and subsequently alter its function as

61 catalyze the highly specific biosynthesis of glycosidic bonds and, as such, are important both as dru

62 tivities: N-glycosylase (hydrolysis of the N-glycosidic bond) and AP lyase (elimination of the 3'-pho

63 n by the C2-alkoxide, an essentially cleaved glycosidic bond, and a slight shortening of the endocycl

64 are both in the anti conformation about the glycosidic bond, and both ribose rings are in approximat

65 ge backbone' conformation, wherein the inter-glycosidic bond angles were held constant at the mean of

66 asic sites from the formal hydrolysis of the glycosidic bond (AP) and several oxidized abasic lesions

67 When the glycosidic bonds are equatorial (e), the torque is zero,

68 n of SEC and FTIR data showed that alpha-1,6-glycosidic bonds are more frequently split in pressurize

69 osyl urea derivatives, in which the O- and N-glycosidic bonds are replaced with the urea-glycosidic l

70 eonine residues of a protein via an O-linked glycosidic bond) are largely unknown.

71 presenting three of the four main classes of glycosidic bond, are formed with thioglycoside donors ac

72 ering by the value of the Psi angle for this glycosidic bond, are populated in solution.

73 f the cofactor to allow rotation about the N-glycosidic bond as it is reduced in the hydride transfer

74 the dA(6) base protons are typical of a syn glycosidic bond at the modified base.

75 degradation technique that only cleaves the glycosidic bond at the reducing end by beta-elimination

76 bose moiety of the substrate and cleaves the glycosidic bond at the very last stage.

77 h a 3-OH group and a 4-OH group (or alpha1-4-glycosidic bond) at the acceptor subsite +1 for the cata

78 acetolysis susceptible, indicative of a 1,6 glycosidic bond between CPS and the GlcNAc C-6.

79 NagZ hydrolyzes the beta-1,4 glycosidic bond between N-acetylglucosamine and anhydro-

80 alyltransferase catalyzes the formation of a glycosidic bond between N-acetylneuraminic acid and the

81 rns in terms of preferential cleavage of the glycosidic bond between O- and fructose C2 in both inuli

82 es early stage assembly of the acidic labile glycosidic bond between sugar and 2-methylchromone aglyc

83 ol+base)-H]-, resulting from cleavage of the glycosidic bond between the 2'-deoxyribose and base, cor

84 t excise the damaged base by cleavage of the glycosidic bond between the base and the DNA sugar-phosp

85 in three-stranded DNA via hydrolysis of the glycosidic bond between the crosslinked base and deoxyri

86 formation, concomitant with cleavage of the glycosidic bond between the residue undergoing epimeriza

87 Endoglycosidases F2 and H, which cleave the glycosidic bond between the two primary GlcNAc residues,

88 s (GH) are enzymes that mainly hydrolyze the glycosidic bond between two carbohydrates or a carbohydr

89 oiety, but may also involve migration over a glycosidic bond between two different saccharide units.

90 pore cortex PG and catalyzes the cleavage of glycosidic bonds between N-acetylmuramic acid (NAM) and

91 The two most stable structures had trans glycosidic bonds, but distinct pairing geometries, i.e.

92 city of the alpha-face on replacement of the glycosidic bond by the hydroxylamine linkage.

93 One of these LPMOs cleaves glycosidic bonds by oxidation of the C1 carbon, whereas

94 ght also assist in the formation/cleavage of glycosidic bonds by stabilizing positively charged oxoca

95 veling mechanism), hydroxymethylene-assisted glycosidic bond cleavage (HAGBC mechanism), and Maccoll

96 rom this structure, it may be concluded that glycosidic bond cleavage and the induced fit conformatio

97 y is initiated by spontaneous or enzymatic N-glycosidic bond cleavage creating an abasic or apurinic-

98 e kinetics and thermodynamics of gas-phase N-glycosidic bond cleavage induced by nucleophilic attack

99 by its insertion into the active site where glycosidic bond cleavage is catalyzed.

100 N-Glycosidic bond cleavage is much slower, taking place on

101 NDTs catalyze N-glycosidic bond cleavage of 2'-deoxynucleosides via a co

102 n maintaining genome integrity by catalyzing glycosidic bond cleavage of 8-oxoguanine (oxoG) lesions

103 ase, protects genome integrity by catalyzing glycosidic bond cleavage of 8-oxoguanine (oxoG) lesions,

104 genic 8-oxoguanine (oxoG) lesion, catalyzing glycosidic bond cleavage of oxoG to initiate base excisi

105 RCL is an enzyme that catalyzes the N-glycosidic bond cleavage of purine 2'-deoxyribonucleosid

106 RCL is an enzyme that catalyzes the N-glycosidic bond cleavage of purine 2'-deoxyribonucleosid

107 Nonetheless, the glycosidic bond cleavage step was not affected.

108 g by UDG have been studied in the absence of glycosidic bond cleavage using substrate analogues conta

109 -ethenoadenine (A) lesion, and the rate of N-glycosidic bond cleavage was identical to that of the wi

110 reported accounts that IRMPD results only in glycosidic bond cleavage, the fragmentation of singly pr

111 ergy barrier and largest exothermicity for N-glycosidic bond cleavage.

112 lease of the abasic product is faster than N-glycosidic bond cleavage.

113 lyzed protonation of the nucleobase promotes glycosidic bond cleavage.

114 ielded ions characteristic of cross-ring and glycosidic bond cleavage.

115 resistant to both enzyme- and acid-catalyzed glycosidic bond cleavage.

116 binding and base flipping in the absence of glycosidic bond cleavage.

117 sion deoxyribose participate in catalysis of glycosidic bond cleavage.

118 ylation of crystalline cellulose, leading to glycosidic bond cleavage.

119 re known to resist the glycosidase-catalyzed glycosidic bond cleavage; however, the synthesis of such

120 The glycan-specific ions mainly arose from glycosidic bond cleavages (B, Y, C, and Z ions) in addit

121 The relative dissociation thresholds of glycosidic bond cleavages and cross-ring cleavages were

122 The results suggest that glycosidic bond cleavages are charge-induced while cross

123 vatized glycans predominately generates C1-O glycosidic bond cleavages retaining the charge on the re

124 The activation barriers of glycosidic bond cleavages were found to depend on the si

125 acts to yield abundant cross-ring cleavages, glycosidic bond cleavages, and combinations of these typ

126 all possible heparin/HS sequences solely by glycosidic bond cleavages, without the need to generate

127 accharide and disaccharide ions derived from glycosidic bond cleavages.

128 es (G4 and G6 in (rGACGAGUGUCA)(2)) in a syn glycosidic bond conformation and forming a sheared GG pa

129 o modes, and the alternation, if any, of the glycosidic bond conformation between syn and anti.

130 of the templating base to maintain the anti glycosidic bond conformation in the binary complex in a

131 udouridine synthase, strongly prefer the syn glycosidic bond conformation, while that of the nonreact

132 e of the modified template adenine with anti glycosidic bond conformation, without disturbing critica

133 In both cases, the modified C adopts an anti glycosidic bond conformation; the equilenin distal ring

134 Both syn and anti glycosidic bond conformations are energetically feasible

135 sociated with the nucleophilic cleavage of N-glycosidic bond constitutes a major factor contributing

136 f uracil-DNA glycosylase hydrolysis of the N-glycosidic bond, converting 2'-deoxyuridine in DNA to an

137 nsition states are late with largely cleaved glycosidic bonds coupled to pyranosyl ring flattening ((

138 excited anion radical that undergoes N1-C1' glycosidic bond dissociation rather than relaxation to i

139 on is reversed by hydrolases that cleave the glycosidic bonds either between ADP-ribose units or betw

140 eometric changes in the anions show that the glycosidic bond exhibits little change with excess charg

141 ines by reversible homolytic scission of the glycosidic bond following the dictates of the Fischer-In

142 , is described that allows for hydrolysis of glycosidic bonds for both hexose- and N-acetylhexosamine

143 s a control element in enzymic processes for glycosidic bond formation and hydrolysis are discussed.

144 Formidable challenges include glycosidic bond formation between ribose and the canonic

145 They catalyze a glycosidic bond formation between sugar donors and sugar

146 Both the C2-nitrogen transfer and the glycosidic bond formation proceed stereoselectively, all

147 a modification not directly involved in the glycosidic bond formation, 6F-N-acetyl-d-galactosamine (

148 on of an external nucleophile and subsequent glycosidic bond formation.

149 rides and the development of new methods for glycosidic bond formation.

150 g protecting groups on the donor favor alpha-glycosidic bond formation.

151 containing the characteristic ribose-ribose glycosidic bond formed during poly(ADP-ribosyl)ation.

152 nvolving excision of the nucleobase at the N-glycosidic bond forms abasic sites.

153 onfiguration is retained following gas-phase glycosidic bond fragmentation during tandem mass spectro

154 leavage channels that "protect" the N-linked glycosidic bond from cleavage.

155 protecting group is a bulky silyl ether or a glycosidic bond; however, even with a 3-O-benzyl ether,

156 s of AAG-catalyzed (k(st)) and spontaneous N-glycosidic bond hydrolysis (k(non)) for damaged and unda

157 ism in which the key amino acids driving the glycosidic bond hydrolysis act as catalytic acid/base an

158 Previous studies show that N-glycosidic bond hydrolysis follows a stepwise (S(N)1) me

159 the active site by exclusively impairing the glycosidic bond hydrolysis step.

160 icient despite the relatively slow rate of N-glycosidic bond hydrolysis.

161 atalytic itineraries" during the cleavage of glycosidic bonds, illustrating the relationship between

162 ith restricted diffusion (rocking) about the glycosidic bond in addition to sugar repuckering was cap

163 produced by mammals capable of cleaving the glycosidic bond in chitin.

164 ejects the proton analogous to the cytosine glycosidic bond in DNA.

165 calar couplings and conformations around the glycosidic bond in oligonucleotides.

166 the anomeric effect for introduction of an O-glycosidic bond in order to direct the introduction of a

167 AdoCbl), in which the configuration of the N-glycosidic bond in the Ado ligand is inverted [(alpha-ri

168 be facilitated by binding the bases with the glycosidic bond in the anti and syn conformation, respec

169 eity involving a syn-anti equilibrium of the glycosidic bond in the modified adenine residue.

170 s the polyoxygenated saccharide and a labile glycosidic bond in the nucleosides, these reactions can

171 isotope effect (EIE) for heterolysis of the glycosidic bonds in 5'-methylthioadenosine and in 2-(p-n

172 topological arrangement of the two bases and glycosidic bonds in a given base-pair.

173 G and AlkA are therefore able to hydrolyze O-glycosidic bonds in addition to N-glycosyl bonds.

174 Cellulase enzymes cleave glycosidic bonds in cellulose to produce cellobiose via

175 dicating the ability of MGIIa_P to hydrolyse glycosidic bonds in complex sugars in PRE.

176 nsertion and subsequent elimination to break glycosidic bonds in crystalline cellulose.

177 To achieve cleavage of the glycosidic bonds in host glycans, S. pneumoniae deploys

178 e ability to perform selective hydrolysis of glycosidic bonds in mogroside V, converting it to siamen

179 Challenges in the assembly of glycosidic bonds in oligosaccharides and glycoconjugates

180 opening polymerization to generate multiple glycosidic bonds in one simple chemical step, allowing u

181 structurally related enzymes that hydrolyze glycosidic bonds in pectin, and are important extracellu

182 enzymes that catalyze oxidative cleavage of glycosidic bonds in polysaccharides in the presence of a

183 s (LPMOs) catalyze the oxidative cleavage of glycosidic bonds in recalcitrant polysaccharides, such a

184 e of electrons to oxidize the C1 position of glycosidic bonds in starch substrates, but not in cellul

185 -xylanases (xylanases) hydrolyse the beta1,4 glycosidic bonds in the backbone of xylan.

186 ctor analogs with thio linkages instead of O-glycosidic bonds in the oligosaccharide backbone.

187 ases (LPMO10s) use redox chemistry to cleave glycosidic bonds in the two foremost recalcitrant polysa

188 o evidence that conformational strain of the glycosidic bond induced by serine pinching plays a major

189 However, when the glycosidic bond is axial (a), torque is generated, causi

190 and two hydrogen bond acceptors because the glycosidic bond is C-C rather than C-N as in uridine.

191 ting agent is that in which the newly formed glycosidic bond is cis to the epoxide moiety.

192 te transition state in which cleavage of the glycosidic bond is coupled to the transfer of a proton f

193 size that the cause of the lability of the N-glycosidic bond is due to the combined steric and electr

194 KIE (=1.201 +/- 0.021) indicate that (i) the glycosidic bond is essentially completely broken in the

195 displacement mechanism: the cleavage of the glycosidic bond is facilitated by the nucleophilic parti

196 ite adjacent to the anomeric carbon of the N-glycosidic bond is suggestive of direct attack by water,

197 The stereoselective formation of 1,2-cis-glycosidic bonds is challenging.

198 The wild-type enzyme cleaves the N-glycosidic bond, leaving the ribose ring in the flipped

199 nitial substrate; with increasing numbers of glycosidic bonds, less glucose is formed.

200 c activity of ChiA was specific for beta,1-4 glycosidic bonds located between GlcNAc monomers in chit

201 low-mass negative ions containing the intact glycosidic bond (m/z 225, 207, 189, 165, 164, 139), whic

202 The enzymatic formation of glycosidic bonds may be catalyzed by the transfer of the

203 re due to the metabolic instability of the O-glycosidic bond (O-mannosides).

204 This is due in part to cleavage of the glycosidic bond occurring prior to the peptide backbone

205 echanism to catalyze the hydrolysis of the N-glycosidic bond of 2'-deoxyuridine (2'-dUrd) in DNA as t

206 The metabolic instability in vivo of the glycosidic bond of 2,5, 6-trichloro-1-(beta-D-ribofurano

207 The reaction involves hydrolysis of the N-glycosidic bond of a particular deoxyguanosine residue,

208 The half-life of the glycosidic bond of an FoU residue in single-stranded DNA

209 lity of the deficient variants to cleave the glycosidic bond of beta-NAD(+) into nicotinamide and ADP

210 groups showed that DspB hydrolyzed the 1-->4 glycosidic bond of beta-substituted N-acetylglucosamine,

211 ely recognize the anti conformation of the N-glycosidic bond of cAMP.G.U pairs occur frequently and h

212 uracil DNA glycosylase (UDG) hydrolyzes the glycosidic bond of deoxyuridine in DNA by a remarkable m

213 Uracil DNA glycosylase (UDG) cleaves the glycosidic bond of deoxyuridine in DNA using a hydrolyti

214 a powerful N-glycohydrolase that cleaves the glycosidic bond of deoxyuridine in DNA.

215 ir pathway, the hydrolytic cleavage of the N-glycosidic bond of deoxyuridine in DNA.

216 th the Ser88 pinching finger) shows that the glycosidic bond of dU has been cleaved, and that the enz

217 trate but instead by the reactivity of the N-glycosidic bond of each substrate.

218 glucuronidase, an enzyme that hydrolyzes the glycosidic bond of glucuronides to generate the parent c

219 nd 26, hydrolyze glucomannan by cleaving the glycosidic bond of mannosides at the -1 subsite.

220 at LytB cleaves the GlcNAc-beta-(1,4)-MurNAc glycosidic bond of peptidoglycan building units.

221 (UDG) catalyzes hydrolytic cleavage of the N-glycosidic bond of premutagenic uracil residues in DNA b

222 s a consequence of the C-C (rather than C-N) glycosidic bond of pseudouridine, the otherwise common d

223 The glycosidic bond of psi32 is in the anti configuration an

224 ine DNA glycosylase (Tdg), which cleaves the glycosidic bond of the bases to give potentially harmful

225 Rotation about the glycosidic bond of the dCTP residue to this abnormal pos

226 ncorrelated rotations are observed about the glycosidic bonds of a partially de-methyl-esterified dec

227 hydrolase (PARG) catalyzes the hydrolysis of glycosidic bonds of ADP-ribose polymers, producing monom

228 talline cellulose and hydrolyze the beta-1,4-glycosidic bonds of cellulose to produce fermentable sug

229 s suggested that phenolic hydroxyls, but not glycosidic bonds of melanoidin-bound phenolics are cleav

230 yses reveal that correlated rotations around glycosidic bonds of monosaccharide subunits at and immed

231 that catalyse the endohydrolysis of beta-1,4-glycosidic bonds of partially acetylated chitosan to rel

232 soamylase is essential to debranch alpha-1,6-glycosidic bonds of starch, yielding linear amylodextrin

233 The enzymatic cleavage of the nicotinamide-glycosidic bond on nicotinamide adenine dinucleotide (NA

234 he fungus Trichoderma reesei that hydrolyzes glycosidic bonds on cellulose randomly.

235 human methylpurine DNA glycosylase cleaves N-glycosidic bonds on RNA and that human apurinic/apyrimid

236 ed in cellular DNA due to instability of the glycosidic bond, particularly at purines and various oxi

237 an important fungal ligand for SP-D and that glycosidic bond patterns alone can determine if an exten

238 ses have broad specificity for hydrolysis of glycosidic bonds, potentially increasing their functiona

239 Nucleosides fragmented at the N-glycosidic bond provide nucleobase and/or ribose or 2'-d

240 ides, IRMPD causes extensive cleavage of the glycosidic bonds, providing structural information about

241 CH or sugar edge) and the orientation of the glycosidic bonds relative to the hydrogen bonds (cis or

242 ein, we disclose that compounds having the O-glycosidic bond replaced with carbon linkages had improv

243 ease selectivity of alpha-1,4 over alpha-1,6 glycosidic bonds, resulting in fewer alpha-1,6 linked re

244 on on the mannoside phenyl ring ortho to the glycosidic bond results in large potency enhancements se

245 The presence of the glycosidic bond results in the stereoselective induction

246 ces induce differences in the sugar puckers, glycosidic bond rotation, and backbone conformations.

247 iring, base stacking, backbone conformation, glycosidic bond rotation, and sugar puckering in the stu

248 , for example, that Cel7A cleaves about four glycosidic bonds/s during processive hydrolysis.

249 N-glycosidic bond scission is then facilitated by a backbo

250 Thus, hTDG specificity depends on N-glycosidic bond stability, and the discrimination agains

251 ase cleavage is dependent on the intrinsic N-glycosidic bond stability.

252 be more selective and also possess increased glycosidic bond stability.

253 omodeoxyuridine, dT) or have a more stable N-glycosidic bond (such as dT).

254 g mispair formation, but it also renders the glycosidic bond susceptible to base cleavage by DNA repa

255 physiologically relevant reverse reaction of glycosidic bond synthesis and thereby require prior know

256 The vast majority of glycosidic-bond synthesis in nature is performed by glyc

257 Cleavage of the N-glycosidic bond that connects the nucleobase to the back

258 In contrast, the beta-D-GlcNAc-(1-->3)-D-Gal glycosidic bond that connects the two Le(x) trisaccharid

259 acid with alternating beta-1,4 and beta-1,3 glycosidic bonds that can be repeated 20,000 or more tim

260 tion through a spontaneous hydrolysis of the glycosidic bond, the ability of Rev1 to stabilize an aba

261 Following cleavage of the glycosidic bond, the liberated hemiacetal spontaneously

262 ectivity in the formation of 1,2-cis-2-amino glycosidic bonds, the glycosylation reaction is hampered

263 thesis of the so-called difficult classes of glycosidic bond: the 2-deoxy-beta-glycopyranosides, the

264 repeating unit incorporates a 1,2-cis-alpha-glycosidic bond; the problematic 1,2-trans-galactosidic

265 ither cross-ring cleavages or rupture of the glycosidic bonds, thereby allowing an unambiguous assign

266 uanosine adopts a syn conformation about the glycosidic bond; thermal melting studies and molecular m

267 esions and catalyzes the hydrolysis of the N-glycosidic bond to initiate the base excision repair pat

268 catalyzing the hydrolytic cleavage of the N-glycosidic bond to release the damaged nucleobase.

269 osine, and catalyzes the hydrolysis of the N-glycosidic bond to release the lesion base and initiate

270 n bonds, permitting dA* to rotate around the glycosidic bond to syn and incorporate dT via a Hoogstee

271 e on the nucleophilic aspartate (264) as the glycosidic bond to the aspartate is broken during the br

272 Glucosidases are enzymes that hydrolyze beta-glycosidic bonds to release non-reducing terminal glucos

273 ermore, lysozyme catalyzed the hydrolysis of glycosidic bonds to the end of the linear substrate but

274 e for an intermediate conformation about the glycosidic bond, unlike in the A(3)AR/3 complex, which f

275 ss units to its molecular mass and makes the glycosidic bond unusually labile during mass spectral an

276 demonstration of the anomeric memory of the glycosidic bond upon fragmentation.

277 enzymes that catalyze oxidative cleavage of glycosidic bonds using molecular oxygen and an external

278 ttention owing to their abilities to disrupt glycosidic bonds via oxidation instead of hydrolysis and

279 de thioglycosides containing 1,2-cis-2-amino glycosidic bonds, via cationic nickel-catalyzed glycosyl

280 ing flipping and the conformation of the 1,4-glycosidic bond was observed.

281 ion 1175-1157cm(-1), linked with breakage of glycosidic bonds, were the most useful for diagnostic mo

282 ts unexpected lability with respect to its N-glycosidic bond when compared with its corresponding can

283 xist in anti or syn conformations around the glycosidic bond when paired opposite to U or G in the co

284 nge results from the torque generated by the glycosidic bonds when a force is applied to the pectin m

285 triguing because the anomeric oxygen forms a glycosidic bond, which means that the reaction must proc

286 ides possess the anti conformation about the glycosidic bond, while in the former, half possess the a

287 G adopted a syn orientation about the glycosidic bond, while the sugar puckers of A and C were

288 nd sialic acid receptors linked via alpha2-3 glycosidic bonds, while human-adapted hemagglutinins bin

289 a predominantly anti conformation about the glycosidic bond with a variety of conformations about th

290 r to direct the introduction of a bridging C-glycosidic bond with the desired stereochemistry.

291 Enzymes in this family hydrolyze beta-1,4-glycosidic bonds with inversion of the stereochemistry a

292 saccharides linked through 1,3- and 1,4-beta glycosidic bonds with subtle differences in structure th

293 w that each G flips independently around the glycosidic bond, with the anti G flipping to syn first.

294 )-meG adopts an anti conformation around its glycosidic bond, with the methyl group in the proximal o

295 g the backbone are linked, through alpha-1,3-glycosidic bonds, with fucose branching at C-2, and one

296 roduct ions that result from dissociation at glycosidic bonds, with little occurrence of dissociation

297 Ltgs cleave the glycosidic bonds within bacterial peptidoglycan allowing

298 fragment ions predominantly from cleavage of glycosidic bonds without breaking the peptide bond.

299 y providing a means for 1,2-trans-equatorial glycosidic bonds without recourse to neighboring group p

300 which selectively cleaves the nicotinamide's glycosidic bond yielding (tz)ADP-ribose.