ライフサイエンスコーパス: glycosidic linkage

1 he natural sugar N-methylfucosamine in alpha-glycosidic linkage.

2 generally limited to catalysis of one unique glycosidic linkage.

3 ch for the stereoselective introduction of a glycosidic linkage.

4 only two unusual conformations at the LacNAc glycosidic linkage.

5 formed best for the installation of the beta-glycosidic linkage.

6 are distinguished by atomic contacts at the glycosidic linkage.

7 ome of which differ by no more than a single glycosidic linkage.

8 esidues, which are present in a mucin-type O-glycosidic linkage.

9 +II) for the reducing end from the scissile glycosidic linkage.

10 on the carbon atom that participates in the glycosidic linkage.

11 silyl ether or to the acetal of an existing glycosidic linkage.

12 ons by means of O -> S/Se replacement at the glycosidic linkage.

13 tose residue onto core fucose via a beta-1,4 glycosidic linkage.

14 d change the orientation and dynamics of the glycosidic linkage.

15 fering only by the configuration of a single glycosidic linkage.

16 n, regiochemistry and stereochemistry of the glycosidic linkage.

17 was connected to the sequence by a beta(1-6) glycosidic linkage.

18 y known enzymes to be able to hydrolyze this glycosidic linkage.

19 the inversion of the configuration of the N-glycosidic linkage.

20 t high concentration was key to making the C-glycosidic linkage.

21 to be assigned to the nonreducing side of a glycosidic linkage.

22 e efficient in extracting dyes, but preserve glycosidic linkages.

23 formation in oligosaccharides containing 1,6-glycosidic linkages.

24 and certain chondroitin sulfates at beta-1,4 glycosidic linkages.

25 ment ions, primarily through dissociation at glycosidic linkages.

26 rmation of the pyranose ring and the type of glycosidic linkages.

27 presence of multiple conformations about the glycosidic linkages.

28 cell wall, contain mannose in either O- or N-glycosidic linkages.

29 s, despite the high local flexibility of the glycosidic linkages.

30 eaction rates depend on the conformations of glycosidic linkages.

31 lysis of alpha-glycosidic linkages than beta-glycosidic linkages.

32 e to changes therein and covers all types of glycosidic linkages.

33 lations of CWPs and enzymes with activity on glycosidic linkages.

34 onsiderable rotational freedom about their O-glycosidic linkages.

35 branched a-glucan polymers with up to 20 cis-glycosidic linkages.

36 isomers of sucrose that differ only by their glycosidic linkages.

37 iated by the anomerism and position of their glycosidic linkages.

38 lactose (AAT), and three consecutive 1,2-cis-glycosidic linkages.

39 osed of 13 different sugars and 21 different glycosidic linkages.

40 etyl groups that prevent rotation around the glycosidic linkages.

41 -galactose (AAT) and two consecutive 1,2-cis glycosidic linkages.

42 e-active enzyme can synthesize both a- and B-glycosidic linkages.

43 oyl ester participation to introduce 1,2-cis-glycosidic linkages.

44 haride units and/or the orientation of their glycosidic linkages.

45 an-II, cleaving all but 1 of its 21 distinct glycosidic linkages.

46 ight on gas-phase dissociation mechanisms of glycosidic linkages.

47 ansferase family members to catalyze beta1-2 glycosidic linkages.

48 saccharides differing in the position of the glycosidic linkage (2alpha-mannobiose, 3alpha-mannobiose

49 ural substrates harboring the Fucalpha1-2Gal glycosidic linkage, a xyloglucan-derived nonasaccharide,

50 idases, which catalyze the hydrolysis of the glycosidic linkages, a function not required for the bio

51 Moreover, RMDs had greater proportion of B-glycosidic linkages, a-/B-reducing end, DB, TDF, and low

52 For the alpha-O-GalNAc-Ser derivative, the glycosidic linkage adopts a high-energy conformation, ba

53 oreover, RMDs had greater proportion of beta-glycosidic linkages, alpha-/beta-reducing end, DB, TDF,

54 the first time the high efficiency of GC-MS glycosidic linkage analysis data for MVDA.

55 tions from AF4, carbohydrate composition and glycosidic linkage analysis for the dominating populatio

56 idase discriminates on the basis of both the glycosidic linkage and the sulfation pattern within its

57 The glycosidic linkages and acetamido side-chains are predic

58 the primary structure with identification of glycosidic linkages and anomeric configuration was as fo

59 ent position is diversified to fit different glycosidic linkages and monosaccharide residues.

60 te preference for alpha(1-6) over alpha(1-4) glycosidic linkages and produces glucose from isomaltose

61 Synthetic glycans (SGs) containing glycosidic linkages and structures not identified in nat

62 nt structural conformation i.e. variation in glycosidic linkages and sulphate group orientation.

63 led to the selective hydrolysis of flavonol glycosidic linkages and the inducible degradation of fla

64 ccharide possesses three consecutive 1,2-cis-glycosidic linkages and two rare sugar units, i.e., d-Fu

65 instance, the sugar is aminoglucose in beta-glycosidic linkage, and in the other, two enantiomers ha

66 n the sugar itself, the presence and form of glycosidic linkage, and the environment in the crystal,

67 types, sugar types, chemical modifications, glycosidic linkages, and anomeric states.

68 However, the rare monosaccharides, cis-glycosidic linkages, and O-acetylation represent signifi

69 including monosaccharides, oligosaccharides, glycosidic linkages, and polysaccharides were determined

70 ha-glucan with (alpha1-->3) and (alpha1-->6) glycosidic linkages, and was similar in structure to a p

71 iomers possessing the natural sugar in alpha-glycosidic linkage are the most potent inhibitors of the

72 e mutant glycosidases, that can readily form glycosidic linkages are addressing a lack of a wide rang

73 enzyl, and p-bromobenzyl ethers, esters, and glycosidic linkages are stable to these reaction conditi

74 GlycoSeq employs rules of glycosidic linkage as defined by glycan synthetic pathwa

75 For oligosaccharides containing glycosidic linkages at the 6-position (1-->6 linked), va

76 ides species ferment fructans with different glycosidic linkages: B. thetaiotaomicron ferments levan

77 glycoconjugates bearing the 1,2-cis-2-amino glycosidic linkages because the saccharide thioglycoside

78 By catalysing the breakdown of beta-1, 4-glycosidic linkages, beta-glucosidases produce free ferm

79 flight mass spectrometry confirmed a direct glycosidic linkage between CPS and PG and showed that a

80 s involved were the synthesis of the 1,2-cis-glycosidic linkage between galactose and the linker (spa

81 a variety of cells and tissues, cleaves the glycosidic linkage between glucuronic acid (GlcA) and a

82 essential glycosyltransferase that forms the glycosidic linkage between N-acetyl muramyl pentapeptide

83 They cleave the glycosidic linkage between N-acetylmuramoyl and N-acetyl

84 The dihedral angles that describe the glycosidic linkage between the A and B rings for the two

85 chondroitin sulfates by cleaving the beta1,4-glycosidic linkage between the glycan units of these pol

86 Nucleosides are defined by their unusual C-C glycosidic linkage between the nucleobase and the monosa

87 sing on-tissue acid hydrolysis to cleave the glycosidic linkage between the polysaccharide (core and

88 potent purine nucleoside antibiotic with a C-glycosidic linkage between the ribosyl moiety and the py

89 er truncation or changing stereochemistry of glycosidic linkage between the tetrasaccharide and the t

90 The key steps are the creation of the glycosidic linkage between the trisaccharide donor, used

91 re symmetrically joined, by a "head-to-head" glycosidic linkage between their carbonyl groups (Chart

92 family of enzymes that catalyze formation of glycosidic linkages between diverse donor and acceptor s

93 ymers of different lengths containing labile glycosidic linkages between monomer units necessitating

94 monosaccharide composition, the position of glycosidic linkages between monosaccharides, and the pos

95 -negative bacteria that cleaves the beta-1,4 glycosidic linkages between N-acetylmuramic acid (MurNAc

96 an be characterized by the torsion angles of glycosidic linkages between relatively rigid carbohydrat

97 matic detection and annotation of sugars and glycosidic linkages between sugar units and to proteins,

98 lycoprotein that catalyzes the hydrolysis of glycosidic linkages between terminal sialic acids and ad

99 These 24 substitutions stabilized the N-glycosidic linkage, blocking base loss and subsequent ba

100 on the results of sugar analysis by GC-FID, glycosidic linkage by GC-MS, NMR spectroscopy, and molec

101 on the results of sugar analysis by GC-FID, glycosidic linkage by GC-MS, NMR spectroscopy, and molec

102 ic C-glycosides); and 4) the cleavage of the glycosidic linkage by PNGase A or F (typical for N-glyca

103 couplings originating from both sides of the glycosidic linkage can be used collectively to evaluate

104 y, the anomericity and regiochemistry of the glycosidic linkages carry important biological informati

105 sis of their monosaccharide building blocks, glycosidic linkages, chain length, as well as additional

106 Of the two possible glycosidic linkages, chemically, 1,2-trans linkage is re

107 g in relatively long life-times for distinct glycosidic linkage conformations, despite the high local

108 des composition (stereoisomers), the type of glycosidic linkages (connectivity) and the anomeric conf

109 des composition (stereoisomers), the type of glycosidic linkages (connectivity) and the anomeric conf

110 se isomer of alpha-(1 -> 1) glucose-fructose glycosidic linkage, containing multiple hydroxyl functio

111 meric form, including the anomericity of the glycosidic linkage, demonstrating the power of this tool

112 ry (LC-MS/MS) method for the quantitation of glycosidic linkages derived from disaccharides, oligosac

113 s include oligosaccharides with up to 20 cis-glycosidic linkages, diverse branching patterns, and 11

114 Herein we apply a glycosidic linkage enrichment strategy to identify accum

115 nked glycopeptide analogues that replace the glycosidic linkages extending from the core pentasacchar

116 trehalose oxygen atoms most distant from the glycosidic linkage fluctuated around 7.5 x 10(-14) m(2)/

117 A novel type of cross-link involving a S-glycosidic linkage formed by reacting an abasic site in

118 h sugar residues are all connected by native glycosidic linkages found in natural N-glycans.

119 es (GT) to catalyse formation of the various glycosidic linkages found in the polymer.

120 ) that sulfur-for-oxygen substitution in the glycosidic linkage fundamentally alters the energeticall

121 Stereoselective formation of glycosidic linkages has been the prime focus for contemp

122 -glycosidic bonds are replaced with the urea-glycosidic linkages, has recently emerged with applicati

123 ain of xylose residues connected by beta-1,4 glycosidic linkages, has remained elusive.

124 cated to the synthesis of a pseudaminic acid glycosidic linkage have been unequivocally characterised

125 that have restricted mobilities around their glycosidic linkages have been employed to determine how

126 uctural information, including sugar pucker, glycosidic linkage, hydrogen bonding patterns and stacki

127 Using NMR spectroscopy to monitor glycosidic linkage hydrolysis, we find that only 47% of

128 a reduction of alpha(1-->6) and alpha(1-->2) glycosidic linkages illustrating a reduced degree of bra

129 amine 3-O sulfation at the reducing end of a glycosidic linkage imparts resistance to heparinase I, I

130 ure determined for enzymatic cleavage of the glycosidic linkage in a pyrimidine deoxyribonucleotide.

131 Every glycosidic linkage in HS was assembled by one of these i

132 The metabolic instability of the glycosidic linkage in TCRB prompted us to synthesize the

133 ds a disaccharide that closely resembles the glycosidic linkage in the polylegionaminic acid from the

134 developed to confirm the presence of a beta-glycosidic linkage in the purified reaction product and

135 The construction of the 1,2-trans-glycosidic linkage in the terminal anthrose moiety was a

136 complementary specificities to hydrolyze the glycosidic linkages in agarose, a linear polymer compris

137 The extensive characterization of glycosidic linkages in carbohydrates remains a challenge

138 Glycoside hydrolases (GHs) cleave glycosidic linkages in carbohydrates, typically via inve

139 Cellulases hydrolyze beta-1,4 glycosidic linkages in cellulose, which are among the mo

140 rize anomeric configurations of newly formed glycosidic linkages in complex oligosaccharide synthesis

141 Cellobiohydrolases processively hydrolyze glycosidic linkages in individual polymer chains of cell

142 is a paradigm for the study of other unusual glycosidic linkages in model and parasitic organisms.

143 hich contains two of the most commonly found glycosidic linkages in N-linked oligosaccharides.

144 nd selective identification of alpha/beta1,2-glycosidic linkages in polysaccharides.

145 n and a reducing agent to oxidatively cleave glycosidic linkages in polysaccharides.

146 trometric measurements of glycan structures (glycosidic linkages) in feces, plus aptamer-based assess

147 Challenging glycosidic linkages including alpha-gluco, beta-manno, a

148 The library includes glycosidic linkage information for three hexoses (glucos

149 ng as monoglucosylated oligosaccharides in N-glycosidic linkage interacted with the chaperone to the

150 The C-11' O-glycosidic linkage is highly unusual because it forms an

151 de thioglycosides containing 1,2-cis-2-amino glycosidic linkages is challenging.

152 The enzymatic hydrolysis of O-glycosidic linkages is one of the most diverse and wides

153 ubstrates yet remains highly specific in the glycosidic linkage it creates.

154 An immense variety of sugars and glycosidic linkages leads to an almost unlimited diversi

155 encompasses the construction of an extensive glycosidic linkage library built from synthesized standa

156 n-bond acceptor at the position ortho to the glycosidic linkage may not be required.

157 The use of alkali influenced the glycosidic linkages, molecular mass and thermal stabilit

158 erent core structures sharing a common alpha-glycosidic linkage (O-GalNAc-alpha-Ser/Thr) are critical

159 ygromycin B identified an orientation of one glycosidic linkage of hygromycin B consistent with metal

160 he composition, sequence, length and type of glycosidic linkage of polysaccharides profoundly affect

161 -4"-deoxy-beta-d-glucose to form the 8',1"-O-glycosidic linkage of saccharocin or apramycin, respecti

162 The impact of glycosidic linkage of seven rare and new-to-nature disac

163 The glycosidic linkage of sialic acids is much more sensitiv

164 rate results in the cleavage of the beta-1,4 glycosidic linkage of the substrate chain and the unsatu

165 enzyme known to catalyse hydrolysis of the O-glycosidic linkages of ADP-ribose polymers, thereby reve

166 dase (GAA) cleaves the alpha1-4 and alpha1-6 glycosidic linkages of glycogen and related alpha-glucos

167 aride composed of partially acetylated 1-->4 glycosidic linkages of N-acetylgalactosamine and N-acety

168 the C1-O1 torsion angle (phi) comprising the glycosidic linkages of oligosaccharides.

169 ignificant modulation of geometry around the glycosidic linkages of the FPX constituent monosaccharid

170 ecognition and hydrolysis of B-1,3 and B-1,4 glycosidic linkages of the laminarinase enzyme class, wh

171 The glycosidic linkages of the type 3 capsular polysaccharid

172 assays reveal that both C-22 epimers (the N-glycosidic linkage) of the natural product have similar

173 s ability to catalyze the hydrolysis of beta-glycosidic linkages once endocytosed, whereas equal conc

174 To prevent hydrolysis of acid-labile glycosidic linkages, optimal reaction conditions that ma

175 C-H protons is indicative of the position of glycosidic linkages or other substituents and can be rea

176 Moreover, glycans with unique glycosidic linkages, particularly from prokaryotes, whic

177 Quantitative analyses of monosaccharides, glycosidic linkages, polysaccharides and alcohol-soluble

178 structures can be composed of many possible glycosidic linkage positions and corresponding a/B anome

179 The glycosidic linkage positions are often determined by per

180 Glycosidic linkage preference originates from the minimi

181 stereoselective installation of multiple cis-glycosidic linkages present in amylose has not been poss

182 e chemoselective introduction of a 1,2-trans glycosidic linkage prior to other linkages.

183 ifferentiating some beta isomers of the same glycosidic linkages, provided the monomeric sugar units

184 cture of the pentasaccharide complex found a glycosidic linkage psi torsion angle to be distorted by

185 accharide sequencing, and monosaccharide and glycosidic linkage quantitation.

186 dihedral angles has been determined for each glycosidic linkage relevant for the conformational prefe

187 fficient and stereoselective construction of glycosidic linkages remains one of the most formidable c

188 families acting on both axial and equatorial glycosidic linkages, respectively.

189 at NcAA13 and MtAA13 more frequently oxidize glycosidic linkages separated by multiples of a helical

190 In addition to the characteristic C-glycosidic linkage shared with other C-nucleosides, oxaz

191 A review of its repertoire of glycosidic linkages suggests a minimum of 38 glycosyltra

192 sceptibility of the acid hydrolysis of alpha-glycosidic linkages than beta-glycosidic linkages.

193 re a measure of the amount of alpha- or beta-glycosidic linkages that are formed and a measure of the

194 ately 10(7) y),(5) of the 1-4 "head-to-tail" glycosidic linkages that join the common glucose polymer

195 sembly of an array of biologically important glycosidic linkages that were previously difficult to ob

196 th alterations in levels of fiber-associated glycosidic linkages; these changes in turn correlated wi

197 The antibody recognizes O-GlcNAc in beta-O-glycosidic linkage to both serine and threonine.

198 is bound at the glycerol sn-3 position in O-glycosidic linkage to diacylglycerol, are abundant in pl

199 A direct glycosidic linkage to PG was also demonstrated for serot

200 ucin-type oligosaccharides is the beta 1-->3 glycosidic linkage to the core alpha-N-acetylgalactosami

201 ammalian cells) linked via either an a- or B-glycosidic linkage to the sphingoid backbone (n = a or B

202 gurations and of the (1 --> 4) and (1 --> 6) glycosidic linkages to the solution conformational entro

203 terized and revealed that in the complex the glycosidic linkage torsion angles between the two reduci

204 date exact O-acetylation patterns as well as glycosidic linkage types of sialosides isolated from com

205 nc(II) alkoxide of acceptors establishes the glycosidic linkage under palladium catalysis to give ris

206 te alternating beta-(1-->5) and beta-(1-->6) glycosidic linkages using a single active site.

207 xtend this study to the synthesis of various glycosidic linkages using different sugar series.

208 imultaneous identification of over 90 unique glycosidic linkages using ultrahigh-performance liquid c

209 saccharide lyases (PL) that cleave their 1,4 glycosidic linkages via a beta-elimination mechanism.

210 ach to precision polysaccharides with native glycosidic linkages via living cationic ring-opening pol

211 trols stereoselective formation of 1,2-trans-glycosidic linkages via the arming participation effect.

212 antigen mimics, the derivative bearing the S-glycosidic linkage was conjugated to gold nanoparticles

213 ferases was performed, and the nature of the glycosidic linkages was determined by NMR.

214 While monosaccharide compositions and glycosidic linkages were analyzed by GC-MS, hydrodynamic

215 om proton homonuclear coupling constants and glycosidic linkages were determined from 1H-13C heteronu

216 ctive than aglycones, polyphenols with (2,1) glycosidic linkages were more effective than those with

217 rides containing betaGlcNAc-(1->4)-betaMan O-glycosidic linkages were selectively labeled with (13)C

218 oic acid, with one of the hydroxyl groups in glycosidic linkage with glucuronic acid.

219 ortant glucoside containing multiple 1,2-cis-glycosidic linkages with complete anomeric control by us

220 ransferase in the GT41 family that creates N-glycosidic linkages with glucose and galactose at aspara

221 unction of the class of enzymes that cleaves glycosidic linkages with phosphate, the first mass spect

222 rocycles, melamine and barbituric acid, form glycosidic linkages with ribose and ribose-5-phosphate i

223 It has multiple glycosidic linkages, with 3-Glcp (28.9%), 6-Glcp (18.3%)

224 free energy landscapes obtained for the same glycosidic linkage within different oligosaccharides.

225 des information relating the location of the glycosidic linkage within the sequence of the glycan und

226 can show that the torsions of the different glycosidic linkages within the GPI tetrasaccharide can b