戻る
「早戻しボタン」を押すと検索画面に戻ります。 [閉じる]

コーパス検索結果 (１語後でソート)

通し番号をクリックするとPubMedの該当ページを表示します
1 ncrease expression of the LHbeta gene in the gonadotrope.
2  in the expression of the LHbeta gene by the gonadotrope.
3 duced glycolysis is recapitulated in primary gonadotropes.
4 lishes essential role(s) of SF1 in pituitary gonadotropes.
5  channels in alphaT3-1 cells and primary rat gonadotropes.
6 mechanism of GnIH action in GnRH neurons and gonadotropes.
7 equency of [Ca(2+)](cyt) oscillations in rat gonadotropes.
8 cates a defect of LH regulation in pituitary gonadotropes.
9 f the alpha and LHbeta subunits in pituitary gonadotropes.
10  in clonal (alphaT3-1) and primary pituitary gonadotropes.
11  a signal from the hypothalamus to pituitary gonadotropes.
12 bpopulation of anterior pituitary cells, the gonadotropes.
13 one secretion in isolated male rat pituitary gonadotropes.
14 tenuated activity in trophoblasts but not in gonadotropes.
15 are heterodimeric glycoproteins expressed in gonadotropes.
16 ibin B-specific and selectively expressed in gonadotropes.
17 l expression is lost in mice lacking SF-1 in gonadotropes.
18 igh in pituitary non-gonadotropes as well as gonadotropes.
19 ntil stimulated by FSH secreted by pituitary gonadotropes.
20 ed signaling from brain neurons to pituitary gonadotropes.
21  expression of FSHB, the hormone secreted by gonadotropes.
22  II receptor is expressed in the majority of gonadotropes.
23 coprotein subunit-expressing thyrotropes and gonadotropes.
24 al significance of this factor in developing gonadotropes, a knockdown of p8 in L beta T2 cells was g
25 sic factors critical for embryonic pituitary gonadotrope and thyrotrope cell differentiation have bee
26 ituitary cells and found that it can inhibit gonadotrope and thyrotrope differentiation.
27 ative regulator of reproduction by acting on gonadotropes and gonadotropin-releasing hormone (GnRH) n
28 relatively sustained in alpha T3-1 pituitary gonadotropes and HEK293 cells but is transient in immort
29 e investigated whether FOXO1 is expressed in gonadotropes and if it can modulate LH beta-subunit (Lhb
30 9 induced FSHbeta expression in immortalized gonadotropes and in mouse primary pituitary cells.
31 ssary for specification and expansion of the gonadotropes and Pit1 lineage within the ventral and cau
32 ization is regulated by insulin signaling in gonadotropes and that FOXO1 inhibits Lhb transcription.
33 gest that GATA2 promotes Grem1 expression in gonadotropes and that the gremlin protein potentiates FS
34 r regulation of alpha-GSU gene expression in gonadotropes and thyrotropes in the developing human fet
35 s single copy gene is expressed in pituitary gonadotropes and thyrotropes of all mammals and in place
36 le in differentiation of ventral cell types (gonadotropes and thyrotropes) by inducing Bmp2 expressio
37 ponsible for Cga cell-specific expression in gonadotropes and thyrotropes, and we show here that it e
38 matin immunoprecipitation assay with LbetaT2 gonadotropes, and this effect is enhanced by gonadotropi
39 istal sequences using purified primary mouse gonadotropes as an in vitro model system.
40 ctivin) was relatively high in pituitary non-gonadotropes as well as gonadotropes.
41 le for PROP1 in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and c
42 es (alpha T3-1 and L beta T2) that represent gonadotropes at early and late stages of development, re
43 n activate transcription through the CREs in gonadotropes but not in trophoblasts.
44               We show Grem1 was expressed in gonadotropes, but not other cell lineages, in the adult
45 trope program by inhibiting GATA2 binding to gonadotrope- but not thyrotrope-specific genes, indicati
46 the control of biosynthesis in the pituitary gonadotrope by hypothalamic gonadotropin-releasing hormo
47 n beta subunits in vivo, we deleted Dicer in gonadotropes by a Cre-lox genetic approach.
48 e they were induced only in purified primary gonadotropes by activin A (50 ng/ml) and inhibited by Gn
49                  AA is transported back into gonadotropes by the AA transporter and increases intrace
50 ude that adenoviral-based studies in primary gonadotropes can adequately recognize regulatory element
51 uction of a committed but immature pituitary gonadotrope cell line by directing expression of the onc
52 d the activity of the LHbeta promoter in the gonadotrope cell line LbetaT2.
53 layer of human chorionic villus but not in a gonadotrope cell line that also expresses the alpha subu
54 cursor cell line, alphaT1-1, and an immature gonadotrope cell line, alphaT3-1, identified by using cD
55  cancer cells, is present in mouse pituitary gonadotrope cell lines.
56 lization and GLUT1 expression in a pituitary gonadotrope cell model and in primary gonadotropes, we s
57 monstrated that FOXO1 is expressed in murine gonadotrope cells and that insulin signaling increased F
58 ppear to be due to a change in the number of gonadotrope cells in the pituitary gland.
59  regulated by insulin signaling in pituitary gonadotrope cells is the FOXO subfamily of forkhead tran
60 Fshb expression levels obtained in pituitary gonadotrope cells perifused with varying GnRH pulse freq
61 ne biosynthesis and secretion from pituitary gonadotrope cells, and together, inhibin and activin con
62                                   In LbetaT2 gonadotrope cells, FSHbeta gene induction depended predo
63 ation with its DNA binding cofactor Foxl2 in gonadotrope cells, mice make essentially no FSH and fema
64 lating hormone (FSH), a product of pituitary gonadotrope cells, regulates gonadal function and fertil
65 inhibins suppress FSH synthesis by pituitary gonadotrope cells.
66 ing hormone, which are secreted by pituitary gonadotrope cells.
67 g endogenous expression of SET with siRNA in gonadotrope cells.
68 rgy transfer reporters in live mouse LbetaT2 gonadotrope cells.
69 or-mediated signaling in L beta T2 pituitary gonadotrope cells.
70        In alphaT3-1 mouse anterior pituitary gonadotropes, chronic activation of gonadotropin-releasi
71 dated by reduced gonadotrope expression in a gonadotrope conditional Gata2-knockout model.
72         We incubated AtT-20 cells, pituitary gonadotropes, cultured cerebellar granule cells, and yea
73               Several hypotheses for how the gonadotrope decodes GnRH frequency to regulate gonadotro
74                                  Analysis of gonadotrope deep-sequencing data identified a global reg
75 cate that GnRH activates MKP-2 expression in gonadotropes, dependent upon activation of multiple MAPK
76 unctional transfection studies in the murine gonadotrope-derived alphaT3-1 cell line, we have localiz
77 , follistatin transcription was evaluated in gonadotrope-derived alphaT3-1 cells.
78 t inhibited activin signaling in a pituitary gonadotrope-derived cell line (LbetaT2) in a dose-depend
79 minimal HSV thymidine kinase promoter in the gonadotrope-derived cell line alphaT3-1.
80 SRII expression in rat pituitary cells and a gonadotrope-derived cell line and MIS-mediated activatio
81                Using LbetaT2 cells, a murine gonadotrope-derived cell line, we have evaluated the eff
82 uitary glands mirrored its expression in the gonadotrope-derived cell lines and coincided with the fi
83                  This profile of human fetal gonadotrope development differs from the current mouse m
84 ilure of the entire Pit1 lineage and delayed gonadotrope development.
85 a cell that represents a subsequent stage of gonadotrope differentiation (expression of alpha-subunit
86 , which are necessary for repressing ectopic gonadotrope differentiation.
87        Furthermore, mutants lacking Dicer in gonadotropes displayed severely reduced fertility and we
88 tary data identifies a Gata2-circuit for the gonadotrope-enriched disease-associated Pcsk1 gene, whic
89 ell responses showed that whereas individual gonadotropes exhibited two response states, inactive and
90 hb We demonstrate that poorly differentiated gonadotropes express a TET1 isoform lacking the N-termin
91 onfocal microscopy, we found that most fetal gonadotropes expressed alpha-GSU, LHbeta, and FSHbeta go
92                                              Gonadotropes expressing alpha-GSU and FSHbeta only were
93 which is experimentally validated by reduced gonadotrope expression in a gonadotrope conditional Gata
94 1 bp of the ovine FSHB gene are required for gonadotrope expression of ovine FSHB.
95  BMP binding to activin type II receptors in gonadotropes, facilitating induction of Fshb transcripti
96    In addition, RNA-seq analysis of purified gonadotropes from control and cKO males revealed a profo
97 enic factor-1 (SF-1), a protein required for gonadotrope function.
98  gonadotropin-releasing hormone neuronal and gonadotrope function.
99 their signaling, suggests different roles in gonadotrope functioning.
100                   GnRH stimulation increases gonadotrope GLUT1 expression and translocation to the ex
101 and by Galpha(s) and implicate autocrine and gonadotrope-gonadotrope paracrine regulatory loops in th
102                                 In pituitary gonadotropes, gonadotropin-releasing hormone (GnRH) acti
103 the activation of the G(q/11) protein in the gonadotrope; however, GnRH II is more potent in the stim
104 bunit (FSHbeta) gene expression in pituitary gonadotropes in a frequency-sensitive manner.
105 tuitaries, increasing in proportion to total gonadotropes in both males and females from 14 (approxim
106 y or in pulses, respectively, from pituitary gonadotropes in many vertebrates, and regulate ovarian f
107 ete gonadal and adrenal agenesis, absence of gonadotropes in the pituitary and impaired development o
108 d number of corticotropes, melanotropes, and gonadotropes in the pituitary.
109 FSHB) is expressed specifically in pituitary gonadotropes in vertebrates.
110  alpha-GSU appears to be the lead protein in gonadotropes, in thyrotropes which ultimately express al
111    The terminal differentiation of pituitary gonadotropes is delayed, resulting in transient hypogona
112 e with defective Lhx3 genes are deficient in gonadotrope, lactotrope, somatotrope, and thyrotrope pit
113 hyrotrope cells and SF-1-expressing cells of gonadotrope lineage.
114  some cell types, such as pituitary cells of gonadotrope lineage.
115         Using cAMP and calcium biosensors in gonadotrope living cells, we showed that SET knockdown s
116 a subunit mRNAs, were suppressed in purified gonadotropes of mutant mice.
117         The target cells of GnRH include the gonadotropes of the anterior pituitary gland and the cel
118                         We conclude that the gonadotropes of the anterior pituitary sense glucose ava
119 ceptor (GnRHR) is expressed primarily in the gonadotropes of the anterior pituitary.
120 t IGSF1 is expressed both in thyrotropes and gonadotropes of the pituitary and in Leydig and germ cel
121 heptapeptide enters the regulated pathway in gonadotropes of transgenic mice, and is released in resp
122 cts high level expression to thyrotropes and gonadotropes of transgenic mice.
123 1), is expressed in the pituitary and in the gonadotrope precursor cell line, alphaT3-1, where it is
124 n of an endogenous gene in LbetaT2 pituitary gonadotrope precursor cells.
125  that all three TET enzymes are expressed in gonadotrope-precursor cells, but Tet1 mRNA levels decrea
126 it1, suppressing the ventral GATA2-dependent gonadotrope program by inhibiting GATA2 binding to gonad
127 ferent tissues, such that its direct role in gonadotropes remains uncertain.
128  various patterns of pulsatile GnRH regulate gonadotrope responsiveness remain poorly understood.
129 ver, SF-1 alone is unlikely to fully explain gonadotrope-restricted Tgfbr3l/TGFBR3L expression.
130                     Here, we report that the gonadotrope-restricted transmembrane protein, TGFBR3L, i
131         Loss of DICER-dependent microRNAs in gonadotropes resulted in profound suppression of gonadot
132 n of transcription factors characteristic of gonadotropes, SF1 and ISL1, but no gonadotropin expressi
133 ated with a GnRH receptor antagonist, and 3) gonadotrope-specific Egr1 knockout mice.
134 hances Tgfbr3l expression in control but not gonadotrope-specific Egr1 knockouts.
135 t LHbeta gene promoter acting at a consensus gonadotrope-specific element (GSE) located at position -
136 -subunit gene through transactivation of the gonadotrope-specific element (GSE).
137 er elements between -2871/-750 necessary for gonadotrope-specific expression of ovine FSHB in vivo.
138 n in gonadotropes, we generated and analyzed gonadotrope-specific Gata2 KO mice using the Cre-lox sys
139 ssion of the oncogene SV40 T antigen using a gonadotrope-specific region of the human glycoprotein ho
140                                        Thus, gonadotrope-specific regulation associated with the prox
141                              They all showed gonadotrope-specific regulation since they were induced
142 s on the ovine FSHB promoter associated with gonadotrope-specific regulation/expression, but that mor
143 lucidate the genomic repertoire required for gonadotrope specification and luteinizing hormone beta (
144 e functionally rescued Fshb null mice with a gonadotrope-targeted HFSHB transgene and performed RNA-S
145 secretion from dopamine- or serotonin-loaded gonadotropes, the secretagogue action of PMA develops mo
146   Although synthesized in the same pituitary gonadotropes, the secretion profiles of lutropin (LH) an
147 ariant CREs have similar overall activity in gonadotropes, the variant CREs make a much smaller contr
148                             It gives rise to gonadotrope, thyrotrope, somatotrope, corticotrope and l
149 f the hormone-producing pituitary cell types-gonadotropes, thyrotropes, somatotropes, lactotropes, co
150                The response of the pituitary gonadotrope to gonadotropin-releasing hormone (GnRH) cor
151  we studied the biosynthetic response of the gonadotrope to varying GnRH concentrations, focusing on
152 onadotropin-releasing hormone (GnRH) acts at gonadotropes to direct the synthesis of the gonadotropin
153                    The response of pituitary gonadotropes to gonadotropin-releasing hormone (GnRH) co
154 ional and post-transcriptional regulation in gonadotropes to orchestrate the hypothalamus-pituitary-g
155 yristate-13-acetate (PMA) stimulates as many gonadotropes to secrete as does gonadotropin-releasing h
156        The presence of two GnRH receptors in gonadotropes, together with the differences in their sig
157 that p8 is a stage-specific component of the gonadotrope transcriptome that may play a functional rol
158                                    Pituitary gonadotropes transduce hormonal input into cytoplasmic c
159 genes that are regulated by GnRH in a murine gonadotrope tumor cell line (LbetaT2).
160        To directly address GATA2 function in gonadotropes, we generated and analyzed gonadotrope-spec
161 expand our previous study on GnIH actions in gonadotropes, we investigated the potential signal trans
162 uitary gonadotrope cell model and in primary gonadotropes, we show GLUT1-dependent stimulation of gly
163 When FSHbeta or LHbeta genes were expressed, gonadotropes were non-dividing.
164 s to the pituitary and in close proximity to gonadotropes, whereas the hypothalamic Gnrh3 neurons are

 
Page Top