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1 KR within 9 years and Kellgren-Lawrence (KL) grade.
2 m-CCC, controlling for sex, age, BMI, and TS grade.
3 latforms for testing therapies at each tumor grade.
4 ssed using 2 metrics and correlated with ILA grade.
5 e Ki-67 indices and possibly incorrect tumor grades.
6 f Erectile Function (IIEF-5) and ejaculation grading.
8 on CT scans using the modified Fisher scale (grades: 0, no radiographic hemorrhage; 1, thin [< 1 mm i
9 reviously established prognostic ordinality: grade 1 = no disease progression; grade 2 = development
11 to be relatively mild-50% (5 episodes) were grade 1, 50% (5 episodes) were grade 2, and none were gr
12 ly untreated patients with high tumor burden grade 1-3a FL received obinutuzumab- or rituximab-based
14 ients (American Society of Anesthesiologists grade 1/2), propensity score-matched models, and patient
15 tality was worse in all patients with AS-CA (grade: 1 to 3) than those with lone AS (24.5% vs. 13.9%;
16 rdinality: grade 1 = no disease progression; grade 2 = development of varices; grade 3 = bleeding alo
17 n; lower steroid doses for the management of grade 2 acute GVHD with isolated skin or upper gastroint
18 ts and cervical intraepithelial neoplasia of grade 2 or 3 and cases of cervical cancer and noncervica
22 Thrombolysis in Cerebral Infarction (mTICI) grade 2b to 3 reperfusion (adjusted OR per 30 minutes in
23 ogression; grade 2 = development of varices; grade 3 = bleeding alone; grade 4 = nonbleeding single d
25 event rate was 14% (43 of 307), including 11 grade 3 events and three grade 4 events according to the
27 clear cell, or any poorly differentiated or grade 3 histological subtype, or any FIGO (1988) stage I
29 ll evaluated through 100 days after HCT, and grade 3 or 4 adverse events (AEs) within 2 weeks after v
30 study weeks 1 and 2 and treatment-associated grade 3 or 4 adverse events at least possibly related to
31 f death, serious adverse events, or clinical grade 3 or 4 adverse events through day 5) was similar i
34 nd hypertension (21% and 10%, respectively); grade 3 or 4 immune-related AEs included hepatitis (0% a
37 disease), nonrelapse mortality, and severe (grade 3 or 4) graft-versus-host disease (GVHD), all eval
38 other immune suppressing agents for severe (grade 3 or 4) immune-related adverse events like neuroto
45 ticipants who started chemotherapy had acute grade 3 or worse treatment-emergent adverse events, whic
46 sness and was diagnosed with a Hunt and Hess grade 3 subarachnoid haemorrhage from a ruptured aneurys
48 dverse event (two [1%] of 157 patients, both grade 3), and there were no treatment-related deaths.
54 he most common (>=20% patients in any group) grade 3-4 adverse events were thrombocytopenia (33 [42%]
58 /Flu conditioning was the probable cause for grade 3-4 hematologic adverse events, as they occurred b
60 ifferences were observed in the incidence of grade 3-4 mucositis between treatment groups, in the ITT
63 vivors), and at increased risk of developing grade 3-5 cardiac (4.3 [3.5-5.4] and 5.6 [4.5-7.1]), end
64 e and disabling, life-threatening, or fatal (grade 3-5) health conditions than siblings of the same a
69 -three patients with cerebral gliomas (9 low-grade, 34 high-grade; 9 primary tumors, 34 recurrent tum
71 opment of varices; grade 3 = bleeding alone; grade 4 = nonbleeding single decompensation; grade 5 = m
73 307), including 11 grade 3 events and three grade 4 events according to the Common Terminology Crite
74 pericardial effusion, and hyperkalaemia, and grade 4 increased alanine aminotransferase were reported
75 grade 4 = nonbleeding single decompensation; grade 5 = more than one decompensating event; and grade
77 aser pulsations delivered (low=0 versus high grade=5852, P<0.001) were significantly higher in high-g
79 n asthma (including severity and control) in Grades 7-8 and 9, school performance from Grade 9 (grade
80 in Grades 7-8 and 9, school performance from Grade 9 (grade point sum, non-eligibility for upper seco
81 with cerebral gliomas (9 low-grade, 34 high-grade; 9 primary tumors, 34 recurrent tumors) who had pr
82 Median extraction time (low=0 versus high grade=97 seconds, P<0.001) and median laser pulsations d
83 For grading, 34 (11.7%) were classified as Grade A, 193 (66.1%) as Grade B, and 65 (22.2%) as Grade
87 However, the implications of surviving low-grade ACLF in terms of risk of subsequent high-grade ACL
89 ty tables that include the incidence of high-grade adverse events, defined by the Common Terminology
90 various diagnostic tests were formulated and graded after the expert panel weighed desirable and unde
94 perties and the long-term effects of machine-grading and subsequent restoration of ski runs so as to
95 es between progression rates using automated grading and those using manual grading (beta = .09; P =
96 ional Society of Urological Pathology (ISUP) grade, and clinical stage as traditional risk stratifica
99 on of guidelines for the diagnosis, severity grading, and treatment of sinusoidal obstructive syndrom
107 w have been guided by biomarkers or clinical-grade assays developed to predict patient response and,
109 t can also efficiently bind B cells and high-grade B cell lymphoma (diffuse large B cell lymphoma) ce
111 S); 20 LBCL-IRF4 cases; and 12 cases of high-grade B-cell lymphoma (HGBCL), NOS in patients <=25 year
112 is an emerging precursor to neoplastic high-grade B-cell lymphoproliferation among people with HIV,
115 emorrhage, white matter hyperintensity (WMH) grade, brain and hippocampal volume, and sulcal and vent
116 , when they encoded reward prediction errors graded by confidence, influencing subsequent choices.
117 ) pathways, with penetrance and expressivity graded by genetic and environmental modifiers, via poorl
118 ements, taken at baseline and annually, were graded by reading center graders masked to clinical data
122 a-observer and inter-observer variability in grading can result in overtreatment and undertreatment o
123 An AI system can be trained to detect and grade cancer in prostate needle biopsy samples at a rank
124 e percentage of (Gleason pattern-based) high-grade cancers (PHG) is demonstrated in EAs (p < 0.01) bu
126 s; (3) For patients with cancers in the same grade category, i.e. the high or low grade, the survival
129 s theory, many striatal neurons exhibit such graded changes without bursting near specific actions.
130 Disturbances in glucose homeostasis and low-grade chronic inflammation culminate into metabolic synd
131 neural network was trained to automatically grade conventional radiographs according to the Risser c
133 current colonic adenoma associated with high-grade dysplasia (HGD) colon polyps at baseline colonosco
134 R 4.53, 95%CI 1.34-15.26; P = 0.02) and high-grade dysplasia (HGD) in the original resection (HR 3.60
135 1.09 (95% CI, 0.85-1.33) for low-grade/high-grade dysplasia and 0.14 (95% CI, 0.06-0.22) for GC.
141 ival (OS) based on clinical T/N stage, tumor grade, ER, PR, HER2, number of metastatic sites, and pre
142 entified by standard analysis of the maximum grade events defined by the Common Terminology Criteria
143 incongruence between clinical course and WHO grade exists, reliable biomarkers have been sought.
144 extraction methods may lead to standardised grade extracts, both from native raw materials and by-pr
154 rhabdoid tumors (n = 229) and pediatric high-grade gliomas (n = 401), we show significant association
155 0 patients from five institutions with lower-grade gliomas (World Health Organization grade II and II
156 thods Data in patients with IDH-mutant lower-grade gliomas (World Health Organization grade II/III) a
166 ficantly lower than on systematic biopsy for grade group 1 cancers and significantly higher for grade
167 state-specific antigen [PSA] <=20 ng/mL, and Grade Group 1-2) prostate cancer and 619 men with unfavo
168 y was associated with the fewest upgrades to grade group 3 or higher on histopathological analysis of
169 nical stage cT2cN0M0, PSA of 20-50 ng/mL, or Grade Group 3-5) prostate cancer diagnosed in 2011 throu
170 group 1 cancers and significantly higher for grade groups 3 through 5 (P<0.01 for all comparisons).
172 d in the 3-year incidence of late RT-related grade >= 3 GI (2.5% v 3.9%) or genitourinary toxicity (2
174 s 13 months (95% CI 10-18) for patients with grade >= 3 neutropenia and 10 months (95% CI 8-13) for p
178 and we observed 6 of 28 patients (21%) with grade >=3 immune-related adverse events, consisting of a
180 ications, major complications (Clavien-Dindo grade >=III), and 30-day mortality, according to definit
182 -years were 1.09 (95% CI, 0.85-1.33) for low-grade/high-grade dysplasia and 0.14 (95% CI, 0.06-0.22)
185 ith a normal predicted left atrial pressure (grade I diastolic dysfunction) had a measured pulmonary
186 was found in 23 (11%) patients, dysfunction grade I in 107 (51%), grade II in 31 (14.8%), and grade
189 to explore the extracellular acidity of WHO grade II and III gliomas associated with 1p/19q co-delet
191 patients, dysfunction grade I in 107 (51%), grade II in 31 (14.8%), and grade III in 49 (23.3%) pati
192 tion, left ventricular diastolic dysfunction grade II or III, right ventricular dysfunction and peric
193 wer-grade gliomas (World Health Organization grade II/III) and 1p/19q codeletion status determined wi
194 53678), patients aged at least 12 years with grades II to IV steroid-refractory aGVHD were eligible t
196 s (irAEs), and long-term outcomes of severe, grade III to V irAE-N at a tertiary care center over 6 y
198 Fewer severe complications (Clavien-Dindo grade IIIb or more) were reported in the HMPO(2) group (
199 re indicating clear or almost clear plus a 2-grade improvement in the IGA score for the intertriginou
200 including the number of raphe, calcification grade in raphe, and leaflet calcium volume were assessed
203 grades of the two observers or the majority grades, including those given by the third observer, wer
204 jury grade (adjusted odds ratio, 2.0 per one-grade increase [95% confidence interval {CI}: 1.6, 2.4];
206 insight into the development of chronic, low-grade inflammation and oxidative stress in age-related d
207 llular and molecular processes including low-grade inflammation are major players in the pathogenesis
210 multivariate analysis found that histologic grade, intratumoral S100 dendritic cells, and CD8 T lymp
211 Family history of pancreatic cancer and high-grade IPMN was identified as risk factors for recurrence
217 This study aims to evaluate the readability (grade level) and suitability (appropriateness) of online
219 augmenting the immune response to EBV in low-grade LYG include treatment with interferon-alpha2b, whe
220 Histopathologic subtype, differentiation grade, lymphovascular invasion, perineural invasion, T-s
221 % female) were collected retrospectively and graded manually by six trained readers using the United
222 research has overwhelmingly used laboratory grade materials unsuitable for human clinical use - repr
223 tems, further study of topological states in graded materials, and the development of acoustic device
225 rary methodology that affords bidirectional, graded modulation of gene expression enabled by tiling t
227 the following five histologic subtypes: high-grade myxoid liposarcoma (HG-MLPS); leiomyosarcoma (LMS)
229 this infusion-based glaucoma model exhibits graded neural damage with unimpaired outflow pathways.
231 by the deep learning algorithm as having any grade of emphysema (adjusted hazard ratios were 1.5, 1.7
232 onDeep learning automation of the Fleischner grade of emphysema at chest CT is associated with clinic
233 TR-FTIR for the in situ determination of the grade of liver steatosis at the operation room as a fast
234 predicting the presence, extent, and Gleason grade of malignant tissue for an independent test datase
237 with recurrence in our cohort, the size and grade of the dysplastic focus at the margin were signifi
239 emphysema progression increased with greater grades of emphysema severity within the emphysema group.
240 nal grades, which were either the concordant grades of the two observers or the majority grades, incl
241 atients with Canadian Cardiovascular Society grading of angina pectoris class 1 (n=1107, 18 events).
242 dy analyzed data to assess the incidence and grading of complications and evaluate outcomes associate
243 e Rotterdam criteria and (2) ophthalmologist grading of optic disc photographs for characteristic fea
245 his technical review was developed using the Grading of Recommendations Assessment, Development, and
248 udy Group database with primary central high-grade osteosarcoma of the extremities, treated between 1
250 SOX9 is significantly overexpressed in high-grade PC tumors (P < 0.05) and in chemotherapy-treated p
252 7-8 and 9, school performance from Grade 9 (grade point sum, non-eligibility for upper secondary sch
253 human cancers is associated with high tumor grade, poor survival, and resistance to chemotherapy.
254 , stent thrombosis, higher modified thrombus grade post first device with consequently higher use of
255 based on several parameters (ie, tumor size, grading, proliferative index, localization, mesoappendic
256 by conducting aerial surveys with a consumer-grade quadcopter (DJI Phantom 3), while concurrently rec
258 modules across all intestinal segments, with graded, regional expression of 1 or more marker genes.
261 of concentration gradients, morphogens drive graded responses to extracellular signals, thereby fine-
262 trate that cells treated with pharmaceutical-grade rigosertib (>99.9% purity) or commercially obtaine
264 ase activity thanks to a semi-quantitative 4-grade scale, named respectively PGA (Physician Global As
268 functionally silenced, HR+, CARM1-high, high-grade serous ovarian cancer cells become PARPi sensitive
271 nd Obstetrics (FIGO; 1988) stage IC-IIA high-grade serous, clear cell, or any poorly differentiated o
273 nt study, we report the production of a high-grade spinal cord glioma model in pigs using lentiviral
274 sis were conducted with histologic anal high-grade squamous intraepithelial lesion (A-HSIL) as the de
275 f age-related maculopathy were determined by grading stereoscopic color fundus photographs using the
277 erse events or reflect the continuous, lower grade symptomatic toxicities that are particularly relev
278 eater using the ANN compared to the standard grading system (0.87 vs. 0.79 and 83% vs. 80% respective
280 against logistic regression and the standard grading system by analysing their Receiver Operator Char
284 o autoinflammatory diseases, which cause low-grade systemic inflammation and contribute to several co
285 dance with the CAP, Evans', JPS, MDA and ART grading systems, and interobserver concordance was compa
288 important role in supporting the diagnosis, grading the severity of disease, guiding treatment, dete
289 he same grade category, i.e. the high or low grade, the survival stratification between races is not
291 ium 68 DOTATATE PET/CT, and in cases of high-grade tumors, they were also evaluated with fluorine 18
296 Overall, the mean percentage of correct NV grading was 87.8% using SS-OCTA with B-scans and 86.2% u
298 e significantly associated with higher tumor-grade while 3/5 lncRNAs were also associated with no tum
299 Ordinal outcome was set according to six grades with a previously established prognostic ordinali