ライフサイエンスコーパス: graded

1 adds several characteristics not previously graded.

2 tement, and the strength of the evidence was graded.

3 ents developed, and strength of the evidence graded.

4 d the evidence supporting the conclusion was graded.

5 statement, and the strength of evidence was graded.

6 and evidence supporting each conclusion was graded.

7 tement, and the strength of the evidence was graded.

8 eloped, and the strength of the evidence was graded.

9 all treatment-related adverse reactions were graded 1 or 2 (low-grade).

10 Incidence of adverse events graded 2 or higher was 36.1 versus 41.5 per 100 person-y

11 pharmacokinetic measures, and adverse events graded 2 or higher.

12 nts had at least one adverse event (AE), 56% graded 3-4.

13 The automated classification correctly graded 76% of the low-grade cancers and 71% of the high-

14 Vascular complications were graded according to 'Valve Academic Research Consortium-

15 herapy, including the opacity of choroiditis graded according to a 3-point scale.

16 Health conditions were graded according to a modified version of the Common Ter

17 SUP was graded according to profuseness (dot versus line/drop) a

18 f the lungs were recorded and systematically graded according to severity.

19 Treatment-related adverse events were graded according to the Common Terminology Criteria for

20 aluated blindly by two expert evaluators and graded according to the presence, location and degree of

21 Recorded adverse reactions were graded according to World Allergy Organization criteria.

22 e where the tungsten fraction is judiciously graded across a thickness less than the skin depth of el

23 of BMP target gene transcripts per cell are graded across their expression domains.

24 oportion of clinical visits when the CNV was graded active over 3 years was similar between ranibizum

25 Our results derived from quantitative graded activity-conformation correlations provide experi

26 various diagnostic tests were formulated and graded after the expert panel weighed desirable and unde

27 All images were graded and analyzed for number, location, and distance o

28 st mode on retinogeniculate communication is graded and can be measured even in the absence of classi

29 in 2017 on ski runs, which had been machine-graded and hydroseeded in the 1990s.

30 Toxicities were graded and managed according to each institution's guide

31 m a variety of cellular responses, including graded and proportional dual-output control of transcrip

32 at the time to complete subcomponents of the Graded and Redefined Assessment of Strength, Sensibility

33 The evidence was appraised, rated, and graded, and recommendations were formulated using the Gr

34 The graded architecture in the enameloid provokes a location

35 design elastic metasurfaces, consisting of a graded array of rod resonators attached to an elastic su

36 (AOs), and joint-space narrowing (JSN) were graded as absent, mild, moderate, or severe according to

37 t which the choroidal neovascularization was graded as active (OR, 1.97 for eyes in upper quartile of

38 2 or more monitoring visits when disease was graded as active) versus timely re-treatment (defined as

39 Overall, vulnerable lesions graded as American Heart Association (AHA) type VI showe

40 Tricuspid valve regurgitation was graded as being more severe in 23 (43%) patients at 12+/

41 Biopsy samples were histologically graded as CIN2+ or <CIN2.

42 Evidence was graded as convincing, highly suggestive, suggestive, wea

43 Eyes were graded as early (n = 21) and mild KC (n = 28) based on t

44 r 180 mg of risankizumab, respectively, were graded as experiencing "excellent improvement" versus 29

45 inence in 77.5% of eyelids; the eyelids were graded as having a normal contour in 70.8% of cases.

46 The chain was graded as having no prominence in 77.5% of eyelids; the

47 n seen on OCTA in the deep capillary plexus, graded as high (>20), intermediate (10-20), or low (<10)

48 ility, the changes of internal reflectivity, graded as hyporeflective, moderate, or hyperreflective,

49 certainty of evidence from these studies was graded as low.

50 Severity of interstitial lung disease was graded as none (healthy lung [F0]), mild (F1), moderate

51 articularly when the infection was initially graded as possible.

52 hondral sclerosis and subchondral cysts were graded as present or absent.

53 Of the 137 eyes graded as showing attached vitreous on OCT, 129 eyes had

54 Of the 38 eyes graded as showing complete PVD on OCT, 20 eyes were foun

55 ther diagnosis or epidemiology was, however, graded as very low to moderate.

56 The degree of contact was graded as with or without morphological changes.

57 In general, a graded association was not detected between age at immig

58 Metabolic risk factors showed a graded association with both tortuosity and width of ret

59 Fundus photographs graded at baseline and years 1 and 2 using DRSS were use

60 ing, and/or a constitutional/enteric symptom graded at least as "moderate" severity.

61 lated macular degeneration was diagnosed and graded based on fundus photographs.

62 ostoperative complications were recorded and graded based on impedance to routine daily activity and

63 for trachoma using 2.5x binocular loupe and graded based on the WHO simplified grading system.

64 Non-LAD targets were graded based on their terminal reach toward the apex: im

65 These articles yielded data on 168 BANFF graded biopsies of corresponding skin and mucosa biopsie

66 90 fundus photos of 490 eyes of 370 subjects graded by 2 glaucoma specialists for the probability of

67 The quality of the content was graded by 2 independent graders using a previously valid

68 ding performance on 87 biopsies individually graded by 23 experienced urological pathologists from th

69 , when they encoded reward prediction errors graded by confidence, influencing subsequent choices.

70 Corneas were graded by cornea specialists according to the area and c

71 of neural activity by bottom-up attention is graded by degree of salience of ambient events.

72 The severity of bleeding events (as graded by drop in hemoglobin, need for transfusion, blee

73 ) pathways, with penetrance and expressivity graded by genetic and environmental modifiers, via poorl

74 at both the 6- and 12-month visits and were graded by meiboscores.

75 ements, taken at baseline and annually, were graded by reading center graders masked to clinical data

76 The CFP and ICGA images were independently graded by reading center-certified retinal specialists t

77 Renal lesions were graded by severity of CIN.

78 Complications were graded by severity using the comprehensive complication

79 DR was graded by standard methods as either low risk (no or mil

80 mmarizes all the postoperative complications graded by the Clavien-Dindo classification (CDC) on a nu

81 Separately, the same scans were graded by the NOA.

82 Pathologically, LYG is graded by the number and density of EBV+ atypical B cell

83 Materials and Methods Lesion conspicuity was graded by three readers by using a 0-5 numerical scale o

84 The images were captured and graded by two trained, masked independent physician grad

85 odds of improvement in hepatic steatosis, as graded by ultrasound (OR: 2.40; 95% CI: 1.50, 3.84; I2 =

86 The recommendations were graded by using the GRADE (Grading of Recommendations As

87 ise and sustained neurotransmission requires graded Ca(2+) signals at the presynaptic terminal.

88 y heteromerization of ORAI channels mediates graded Ca(2+) signals that extend the agonist-sensitivit

89 When comparing the graded categories of financial hardship, there was a ste

90 puts generate complex patterns of binary and graded cell fates.

91 hs were collected at annual study visits and graded centrally for late age-related macular degenerati

92 hs were collected at annual study visits and graded centrally for late AMD.

93 hs were collected at annual study visits and graded centrally for late AMD.

94 annual stereoscopic fundus photographs were graded centrally to detect DPED, a well-defined yellow e

95 cin who successfully tolerated a dalbavancin graded challenge.

96 intrinsic connectivity is jointly guided by graded changes along all three dimensions.

97 changes in sensory or motor information with graded changes in firing rate.

98 ctively, the population is able to report on graded changes of temperature.

99 s theory, many striatal neurons exhibit such graded changes without bursting near specific actions.

100 is not clear whether this is done through a graded coding, as in the neocortex, or a truly invariant

101 tance of studies combining physiological and graded cognitive challenges in young adults to investiga

102 While most drugs displayed graded concentration-prophylaxis profiles, protease inhi

103 In this study, graded concentrations of semipermeable membrane device (

104 Developmental enhancers integrate graded concentrations of transcription factors (TFs) to

105 sequencing, we identified both discrete and graded continuous gene-expression differences within the

106 Moreover, graded control can be as fundamental to success as the s

107 ming of their impact during development, and graded degrees of hormonal influences may help explain t

108 oad mean FR distribution is achieved through graded differences in both intrinsic and synaptic proper

109 and psychotic illnesses was associated with graded disruptions in frontoparietal network connectivit

110 f the Drosophila embryo is determined by the graded distribution of Dorsal (Dl), a homolog of the nuc

111 mutant variants, which demonstrated potent, graded dominant-negative effects.

112 We aimed to determine the tolerance to graded dosages of histidine in a healthy adult populatio

113 Healthy adults aged 21-50 y completed graded dosages of histidine supplement (4, 8, and 12 g/d

114 We aimed to determine the effect of graded doses of dietary protein co-ingested with carbohy

115 (-/-), MK2 (-/-), and Zfp36 (-/-) mice with graded doses of lipopolysaccharide (LPS) and various inh

116 The AREDS2-10Y investigators graded each SD-OCT scan for the presence/absence of intr

117 Structural evidence for graded efficacy receptor conformations predicted by rece

118 gradient alloying allows the formation of a graded electronic bandgap, which increases the carrier m

119 Here, we show that graded encodings of noxious stimuli are categorized in a

120 this biosensor in embryos revealed spatially graded ERK activity in the trophectoderm prior to overt

121 A graded exercise stress test was normal.

122 pon completing the V4 recording, a treadmill graded exercise test (GXT) was performed, followed by a

123 with Wnt3a from the cortical hem to regulate graded expression of transcription factors that position

124 markable output of this network derives from graded expression, designated by antigen receptor signal

125 endently associated with infection risk in a graded fashion (e.g., HR = 1.44 (95% CI: 1.24, 1.69) for

126 Median CSS increased in a graded fashion from 13 months [interquartile range (IQR)

127 ner, suggesting that Ryk signaling acts in a graded fashion.

128 increasing LGE and extracellular volume in a graded fashion.

129 ainstem region that controls locomotion in a graded fashion.

130 How binary and graded fate characteristics are patterned across tissues

131 ncoding in DMC arises through compression of graded feature encoding by attractor dynamics underlying

132 ered adhesive lap joints with rounded edges, graded Fibronectin 'adhesive' and an arced adhesive spew

133 OCT images were graded for central macular thickness (CMT) and the prese

134 s fluorescein angiograms and OCT images were graded for choroidal neovascularization type.

135 s between the groups after co-wintering when graded for commercial almond pollination.

136 Each segment was graded for distensional and radiological confidence.

137 ere transmitted to a reading center and were graded for DR and other findings by trained readers.

138 Each eye was graded for DR severity.

139 Spectral domain OCT images were graded for GA area using 2 distinct criteria: (1) comple

140 The 2 anonymized image sets were graded for presence or absence of NV by 12 other graders

141 ng therapy were retrospectively analyzed and graded for the estimation of the safety profile.

142 age-related macular degeneration (AMD) were graded for the presence of a double-layer sign to determ

143 Participants were graded for the presence of each of the following fundus

144 as functional ambulatory category (FAC) were graded for the stroke patients.

145 SD OCT images of participants were graded for vitreomacular traction (VMT), macular hole (M

146 Action priors induced graded free-choice biases and graded frontoparietal moto

147 The ACDiT grading system-graded from 0 to 5b-is applied in this manner but has no

148 al connective tissue that is morphologically graded from tendinous to osseous and develops from bipot

149 onal study examined the eyes of 44 subjects, graded from the first to third keratoconus stages by Ams

150 eripheral lesions (PPL) and DR severity were graded from UWF color images.

151 priors induced graded free-choice biases and graded frontoparietal motor-goal activity, complementari

152 This leads to a graded gene expression response and differences in ex vi

153 r bundle, is composed of stereocilia rows of graded height, a property essential for sensory function

154 these correlations, CST and EZ integrity, as graded herein, account for the minority of BCVA variatio

155 raniofacial complex that is independent of a graded Hh signal.

156 Low baseline eGFR was associated with graded, higher odds of AKI incidence (P value for trend

157 45% reduction in the ventilatory response to graded hypercapnic acidosis vs. controls.

158 -greater indeterminate pulmonary nodule, and graded image quality.

159 Two masked retina specialists graded images for DR and DME, using National Health Serv

160 Histological IRI was graded in 506 grafts from patients who had undergone LT

161 parenchymal fibrosis were semiquantitatively graded in a blinded fashion.

162 Ultrasound images were graded in a masked fashion independently by 2 retina spe

163 PD-L1, PD-L2, CD8, and p16 was performed and graded in a standardized fashion.

164 A subsample was graded in more detail to estimate the prevalence of VMA

165 as more binary-like in the DMC task and more graded in the OIC task.

166 but not ADP (P2Y receptor agonist), caused a graded increase in mean arterial pressure in rats with s

167 Compared to low-risk patients, there was a graded increase in risk of DR/DQ DSA in intermediate (HR

168 greater burden of SDH was associated with a graded increase in risk of incident CHD, with greater ma

169 Multivariable Cox analysis indicated a graded increase in the risk of infection with higher lev

170 re applied to 40 additional images that were graded independently by attendees to refine the consensu

171 OCT and CFP images were graded independently for the presence of nGA and GA, res

172 Graded index (GRIN) lenses are commonly used for compact

173 monstrate that auxin carries high-definition graded information not only in space but also in time.

174 folding and conformational exchange leads to graded inhibition of 4E-BP2:eIF4E binding, shifting 4E-B

175 Sensory stimuli with graded intensities often lead to yes-or-no decisions on

176 sh-resistant elytra, produced by complex and graded interfaces.

177 analysis across the two aetiologies revealed graded intra- and intergroup variations on all four extr

178 laser Doppler flowmetry) was measured during graded intradermal microdialysis perfusion of the endoth

179 nior controls underwent exercise testing and graded isoproterenol infusion to quantify cardiac beta-r

180 The other four brain states reflected graded levels of anesthesia.

181 Co-expression competent cells express graded levels of S- and M-opsins, depending nonlinearly

182 g-pair analysis found support for causal and graded liability effects of cannabis on precuneus struct

183 Swanepoel criteria, graded mild by SSI, and graded low risk by SGS.

184 a module of genes, which is coexpressed in a graded manner and jointly tunes multiple biophysical pro

185 als distinct brain regions that respond in a graded manner as humans process distance information acr

186 hus, mpk-1 ATS class frequencies switch in a graded manner as stem cell daughters begin differentiati

187 ERK nuclear translocation is regulated in a graded manner in response to increasing MKP3 activity.

188 xts of sensory-associated external cues in a graded manner, apparent in the presynaptic activity of t

189 pted cortical activity and arm movement in a graded manner.

190 lix and the three-dimensional structure in a graded manner.

191 Color fundus photographs were graded manually and OCT scans underwent automated image

192 % female) were collected retrospectively and graded manually by six trained readers using the United

193 uency analysis of three layered functionally graded material (FGM) cylinder-shaped shell is studied w

194 one-step route for fabricating functionally graded materials by controlling the stress distribution

195 tems, further study of topological states in graded materials, and the development of acoustic device

196 ng wild-type and mutant embryos in which all graded maternal patterning inputs are eliminated.

197 nic vocalizations provide a quantifiable and graded measure of positive affect that accurately reflec

198 e insights, we propose and compare potential graded-microstructure designs for next-generation batter

199 se defined as meeting no Swanepoel criteria, graded mild by SSI, and graded low risk by SGS.

200 The certainty of evidence was graded moderate for body weight, high for waist circumfe

201 rary methodology that affords bidirectional, graded modulation of gene expression enabled by tiling t

202 The feature-similarity gain model predicts a graded modulation, whereas an alternative model asserts

203 Readers graded more accurately with model assistance than withou

204 We suggest that graded mRNA output is a general feature of morphogen gra

205 Together, these results indicate a graded nature of response mode and suggest that, under c

206 this infusion-based glaucoma model exhibits graded neural damage with unimpaired outflow pathways.

207 n be achieved in a facile manner utilizing a graded neutral density filter, circumventing the need fo

208 Diastolic function was graded normal (N) or dysfunction grade I to III.

209 Graded normalization of the postoperative resting-state

210 CD8 expression was graded on a 0-3 scale.

211 Silicone oil microdroplets were graded on a scale from 0 to 4+ based on the number and s

212 images of upper (UL) and lower lids (LL) was graded on a scale of 0 (lowest degree of MG loss) to 3.

213 AMD features were graded on fundus photographs using the Rotterdam classif

214 Incident AMD was graded on fundus photographs.

215 ory sensory differentiation and instruct its graded pattern are largely unknown.

216 A spatially graded pattern of vascular structural remodeling in peri

217 ery-targeted photothrombosis produced a more graded penumbra at 48 and 120 h.

218 at channel cooperativity can robustly induce graded persistent activity - a single-cell based, multis

219 ticipants' diets in 1992, 1994, and 1996 and graded photoaging severity using microtopography in 1992

220 The mechanisms underlying the regulation of graded photoreceptor synaptic output in this nonspiking

221 As exemplars, homogeneous and graded polymer foams in several motifs, including 3D lat

222 ere found to have definite NE-MNV, and all 6 graded positively for SIRE (sensitivity, 100%).

223 urinergic receptors, P2X4 and P2X7, with the graded production of a gene product, namely the tumour n

224 ompute topological representations of purely graded prostate cancer histopathology images of Gleason

225 An independent reading center graded qualitative and quantitative morphologic features

226 Two blinded readers retrospectively graded radiological abnormalities of the craniofacial re

227 er uniform or non-uniform (e.g. functionally graded, random) offsets, is invariantly a hyperbolic par

228 Coupled aromatic residue rotation was a graded rather than a binary switch, with Y- or W106 side

229 mpilation of the literature supported by the graded recommendations from the expert panel for the opt

230 dult RGCs, and the secondary consequences of graded reductions in Atoh7 dosage.

231 The SLL is a graded refractive index lens, which is realized by using

232 O-OCT en face images and SD-OCT B-scans were graded regarding irregularity and loss of photoreceptor

233 O-OCT en-face images and SD-OCT B-Scans were graded regarding irregularity and loss of photoreceptor

234 modules across all intestinal segments, with graded, regional expression of 1 or more marker genes.

235 es in sarcomere contractile function induced graded regulation of 101 gene transcripts, including MAP

236 sphorylation of kinases can induce on-off or graded regulation of catalytic activity; however, its in

237 ethylation of the VCAM1 promoter resulted in graded RelA/p65 and RNA polymerase II binding that gave

238 There was a graded relationship among CRS, elevated troponin, and CV

239 A clear graded relationship existed between the number of risk f

240 -related anxiety questions was analyzed by a graded response model using the Cai Metropolis-Hastings

241 were estimated using an Item Response Theory graded response model.

242 Graded response models were fit by Cai's Metropolis-Hast

243 phosphorylation occurred within seconds as a graded response to changes in the light intensity and io

244 during regeneration, showing a gated versus graded response, respectively.

245 tal findings show the ubiquitous presence of graded responses and tuning curves in the neocortex, par

246 of concentration gradients, morphogens drive graded responses to extracellular signals, thereby fine-

247 terograde amnesia), together with temporally graded retrograde amnesia covering ~5 y prior to the car

248 cted mean RNFL thickness and SS and manually graded scans for artifact.

249 with vascular dementia when assessed as a 3-graded score (adjusted HR = 1.90 [95% CI = 1.07-3.38]).

250 Extent of initial hemorrhage was graded semi-quantitatively on admission CT scans using t

251 vity of two internal exons and demonstrate a graded series of consensus sequence elements of varying

252 5 acts as a signaling "gatekeeper," enabling graded signaling outputs while filtering weak or spuriou

253 overtones, sounds of burst-pulse character, graded sounds, biphonations, and calls of multiple compo

254 ome clear that animals can exhibit exquisite graded specification to their movements.

255 eir apical surface, forming a characteristic graded 'staircase' structure.

256 Qualified retinal graders reviewed and graded standardised retinal photographs to assess retina

257 emoreflex excitation produced by exposure to graded, steady-state eucapnic hypoxia in middle-aged men

258 In human liver samples, the sensor graded steatosis with an overall accuracy of 93% (kappa

259 ities for constructing protocell arrays with graded structure and functionality and provide a step to

260 goal engagements effectively within the age-graded structure of opportunities and constraints in the

261 Quality assessment graded studies into "strong" (n = 5), "moderate" (n = 4)

262 Nanoporous, density-graded surface of 'black' gallium indium phosphide (GaIn

263 aseline and during the 2-year follow-up were graded systematically for presence of MA.

264 s with complex wavenumbers, valley states in graded systems, or dispersion tuning for valley states.

265 t be processed supported a normal pattern of graded target gene activation and the development of adu

266 The signaling mechanism connecting graded TCR signaling to the generation of varying amount

267 Two readers visually graded the 3D LGE images (conspicuity, artifact, noise)

268 tudies, and a Technical Expert Collaborative graded the body of evidence using the NESR grading rubri

269 terogeneity, and small-study effects, and we graded the evidence according to prespecified criteria.

270 For both eyes, we graded the extent of angioid streaks, that is, their dis

271 diologists assessed each CT in consensus and graded the extent of pulmonary involvement (by percentag

272 A treatment by physical appearance alone and graded the following features relative to the other eye:

273 raphic, and ocular information independently graded the OCT scans for the presence of ONH prelaminar

274 Three radiologists independently graded the presence of liver nodules on a five-point con

275 determined topics for systematic review, and graded the quality of evidence previously summarized by

276 idence, developed conclusion statements, and graded the strength of the evidence.

277 idence, developed conclusion statements, and graded the strength of the evidence.

278 idence, developed conclusion statements, and graded the strength of the evidence.

279 idence, developed conclusion statements, and graded the strength of the evidence.

280 idence, developed conclusion statements, and graded the strength of the evidence.

281 We found that while IEG expression is graded, the expression of multiple IEGs is tightly corre

282 Cognitive, striatal, and sensory regions graded their responses to changes in predicted threat de

283 How this graded-to-binary conversion is implemented in the centra

284 Graded transcription factors are pivotal regulators of e

285 The graded tuning of fast-spiking capacity by the absolute e

286 Tricuspid regurgitation was graded using a five-class grading scheme (mild, moderate

287 All cataracts were graded using LOCS III.

288 Foveal tomograms were graded using our 6-point grading system for foveal hypop

289 acuity (CDVA) and total score, each eye was graded using receiver operating characteristic (ROC) ana

290 Complications were graded using the Clavien-Dindo (CD) classification.

291 Adverse events were graded using the Common Terminology Criteria for Adverse

292 Serum ALT level was graded using the Common Terminology Criteria for Adverse

293 ecommendations were formulated, written, and graded using the GRADE (Grading of Recommendations Asses

294 SSTR ligand uptake was graded using the Krenning score independently by 3 reade

295 ffect estimates for each dietary pattern was graded using the NutriGrade scoring system.

296 mpaired participants, including the diverse, graded variations observed in post-stroke aphasia.

297 , whereas there was considerable overlap and graded variations within and between other subtypes of P

298 mber of injections, and proportion of visits graded with active nAMD over the 5 years were compared b

299 PD-L1 and PD-L2 expression were graded with both the combined positive score (CPS) and t

300 All complications graded with the CDC and CCI and related to the initial a