ライフサイエンスコーパス: granulocyte-macrophage progenitor

1 ssion profile very similar to that of normal granulocyte macrophage progenitors.

2 eloid progenitors but significantly lower in granulocyte-macrophage progenitors.

3 myeloid progenitors but relative sparing of granulocyte-macrophage progenitors.

4 f multilymphoid progenitors and depletion of granulocyte-macrophage progenitors.

5 normal and CML hematopoietic stem cells and granulocyte-macrophage progenitors.

6 typic characteristics of colony-forming unit-granulocyte-macrophage progenitors.

7 ture HSC exhaustion and differentiation into granulocyte-macrophage progenitors.

8 r lymphoid-primed multipotent progenitors or granulocyte/macrophage progenitors.

9 rentiate from common myeloid progenitors and granulocyte/macrophage progenitors.

10 usly proposed, common myeloid progenitors or granulocyte/macrophage progenitors.

11 macrophage differentiation of murine 32Dcl3 granulocyte/macrophage progenitors.

12 rise to either megakaryocyte/erythrocyte or granulocyte/macrophage progenitors.

13 1 gene causes a severe reduction in myeloid (granulocyte/macrophage) progenitors.

14 CSF, along with a hematopoietic shift toward granulocyte macrophage progenitor and myeloid cells.

15 ol I transcription reduces both the leukemic granulocyte-macrophage progenitor and leukemia-initiatin

16 mmon myeloid progenitors committed to become granulocyte-macrophage progenitors and as megakaryocyte-

17 ly unrecognized system of rapid migration of granulocyte-macrophage progenitors and committed macroph

18 Gfi-1 in the common myeloid progenitors and granulocyte-macrophage progenitors and down-regulation o

19 LSCs compared with their normal counterpart granulocyte-macrophage progenitors and myeloblast precur

20 rogenitors to differentiate into bipotential granulocyte/macrophage progenitors and their progeny.

21 1RI in supporting increased proliferation by granulocyte/macrophage progenitors and, surprisingly, mu

22 fferentiating common myeloid progenitors and granulocyte-macrophage progenitors, and 4-1BB was induci

23 etic stem cells, common myeloid progenitors, granulocyte-macrophage progenitors, and megakaryocyte-er

24 Activation of beta-catenin in CML granulocyte-macrophage progenitors appears to enhance th

25 hil/macrophage lineage outputs from a common granulocyte-macrophage progenitor are still not complete

26 Runx1-deficient granulocyte-macrophage progenitors are characterized by

27 progenitors are markedly increased, whereas granulocyte-macrophage progenitors are reduced.

28 the proportion of unmethylated C/EBPalpha in granulocyte/macrophage progenitors by inhibiting Carm1 b

29 lowing infection with cytomegalovirus, human granulocyte-macrophage progenitors carry the viral genom

30 hat its down-regulation in MDS is related to granulocyte-macrophage progenitor cell sensitivity to TR

31 be expressed in bone marrow-derived bipotent granulocyte macrophage progenitor cells (GM-colony formi

32 ng activity of common myeloid progenitor and granulocyte macrophage progenitor cells.

33 cells, common myeloid progenitors (CMPs) and granulocyte-macrophage progenitor cells (GMPs) different

34 terized by a dramatic increase in numbers of granulocyte-macrophage progenitor cells in the marrow an

35 liteal lymphoid nodes, bone marrow cells and granulocyte-macrophage progenitor cells.

36 al, and proliferation of colony-forming unit-granulocyte-macrophage progenitor cells.

37 ATI-2341-mediated release of granulocyte/macrophage progenitor cells from the bone ma

38 s repressed by C/EBPalpha-p42, and in normal granulocyte/macrophage progenitor cells, we detect C/EBP

39 Granulocyte-macrophage progenitors (CFU-GM) were present

40 Unlike normal granulocyte-macrophage progenitors, CML granulocyte-macr

41 ng-term haematopoietic stem cells (HSCs) and granulocyte-macrophage progenitors compared with wild-ty

42 Granulocyte/macrophage progenitors displayed a relativel

43 dd45a-/- and gadd45b-/- colony forming units granulocyte/macrophage progenitors displayed prolonged p

44 rmal granulocyte-macrophage progenitors, CML granulocyte-macrophage progenitors formed self-renewing,

45 I571 on primary leukemic colony-forming unit granulocyte/macrophage progenitors from patients with CM

46 eage, bipotent megakaryocyte-erythrocyte and granulocyte-macrophage progenitors give rise to unipoten

47 expansion of the lin-/Sca-1/c-kit (LSK) and granulocyte macrophage progenitor (GMP) compartments at

48 chronic myelogenous leukemia (CML), abnormal granulocyte macrophage progenitors (GMP) with nuclear be

49 egakaryocyte-erythroid progenitor (MEP), and granulocyte-macrophage progenitor (GMP) cells, accompani

50 ly from both primitive (CD34+CD38-) and late granulocyte-macrophage progenitor (GMP) cells.

51 We traced distinct trajectories through the granulocyte-macrophage progenitor (GMP) compartment show

52 on and increased numbers of DCs, even in the granulocyte-macrophage progenitor (GMP), which does not

53 anscription factor critical for formation of granulocyte-macrophage progenitors (GMP) and leukemic GM

54 etic stem cells (HSC) or more differentiated granulocyte-macrophage progenitors (GMP).

55 y aberrant activation of beta-catenin within granulocyte-macrophage progenitors (GMP).

56 Here we use imaging to track granulocyte/macrophage progenitor (GMP) behaviour in mic

57 kit(+) (LSK), common myeloid progenitor, and granulocyte/macrophage progenitor (GMP) cells.

58 mbers of common myeloid progenitor (CMP) and granulocyte/macrophage progenitor (GMP) populations, and

59 nophil progenitors (EoPs), downstream of the granulocyte/macrophage progenitor (GMP).

60 CBP, the fusion protein selectively expanded granulocyte/macrophage progenitors (GMP) and enhanced th

61 expansion of splenic cells that derive from granulocyte/macrophage progenitors (GMP) compared with w

62 ecifically expands the numbers of LT-HSC and granulocyte/macrophage progenitors (GMP) resulting in ch

63 n clonal expansion of phenotypically defined granulocyte macrophage progenitors (GMPs) and acquisitio

64 els, we show that myeloid differentiation to granulocyte macrophage progenitors (GMPs) is critical fo

65 ivate Evi1 expression in MLL-AF9-transformed granulocyte macrophage progenitors (GMPs) that were init

66 erized by elevated beta-catenin signaling in granulocyte macrophage progenitors (GMPs), which enables

67 -primed multi-potential progenitors (LMPPs), granulocyte-macrophage progenitors (GMPs) and multi-lymp

68 lacked common myeloid progenitors (CMPs) and granulocyte-macrophage progenitors (GMPs) but retained m

69 ogenitors [CLPs]) and CMPs and their progeny granulocyte-macrophage progenitors (GMPs) can give rise

70 that the cell cycle rate heterogeneity among granulocyte-macrophage progenitors (GMPs) determines the

71 uncover a unique spatiotemporal mechanism of granulocyte-macrophage progenitors (GMPs) employed in em

72 We identify a recurrent loss of granulocyte-macrophage progenitors (GMPs) in the bone ma

73 -deficient Rag1(-/-) mice, lineage-committed granulocyte-macrophage progenitors (GMPs) or bone marrow

74 d that common myeloid progenitors (CMPs) and granulocyte-macrophage progenitors (GMPs) preferentially

75 profiles from wild-type and Dicer1-deficient granulocyte-macrophage progenitors (GMPs) revealed that

76 Here, we have identified a population of granulocyte-macrophage progenitors (GMPs) that were high

77 hils and the generation of granulocytes from granulocyte-macrophage progenitors (GMPs) were markedly

78 e granulocyte differentiation in bipotential granulocyte-macrophage progenitors (GMPs), its role in r

79 (CMPs), common lymphoid progenitors (CLPs), granulocyte-macrophage progenitors (GMPs), megakaryocyte

80 ulations: common myeloid progenitors (CMPs), granulocyte-macrophage progenitors (GMPs), megakaryocyte

81 (CMPs), common lymphoid progenitors (CLPs), granulocyte-macrophage progenitors (GMPs), or early thym

82 n aberrant progenitor differentiation toward granulocyte-macrophage progenitors (GMPs), resulting in

83 f the DC progenitors partially overlaps with granulocyte-macrophage progenitors (GMPs).

84 s (CLPs), common myeloid progenitors (CMPs), granulocyte/macrophage progenitors (GMPs), and thymocyte

85 t-term (ST)-HSCs/multipotent progenitors and granulocyte/macrophage progenitors have self-renewal cap

86 rmally high numbers of colonies derived from granulocyte-macrophage progenitors in cultures supplemen

87 ow numbers of myeloid-biased multipotent and granulocyte-macrophage progenitors in the bone marrow, r

88 mpounds exhibited some degree of toxicity to granulocyte/macrophage progenitors in the bone marrow of

89 ative cells, common myeloid progenitors, and granulocyte/macrophage progenitors in the spleen.

90 erythroid (CFU-E), mast cell and bipotential granulocyte/macrophage progenitors in the yolk sac.

91 or myeloid progenitor lineage skewing toward granulocyte-macrophage progenitors, increased colony-for

92 Steady-state numbers of granulocyte-macrophage progenitors, myeloid-lineage cell

93 The granulocyte-macrophage progenitor pool from patients wit

94 ypes through the same myeloid-restricted pre-granulocyte-macrophage progenitor (pre-GM) (Lin(-)Sca-1(

95 lum-induced HSC, multipotent progenitor, and granulocyte/macrophage progenitor proliferation and reac

96 During latency in granulocyte-macrophage progenitors, RC2710 DNA was detec

97 he Id1 gene begins to be up-regulated at the granulocyte-macrophage progenitor stage and continues th

98 ) and acute leukemia evolving from committed granulocyte-macrophage progenitors that have acquired th

99 ng experimental latent infection of cultured granulocyte-macrophage progenitors, the viral genome was

100 d LSC from leukaemias initiated in committed granulocyte macrophage progenitors through introduction

101 y creating a niche postirradiation for human granulocyte-macrophage progenitors via reduced murine CD

102 s increased, but differentiation from CMP to granulocyte/macrophage progenitor was decreased, and the