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1 edral 3-fold axes and the R domains differed greatly.
2 have been reported, their performance varies greatly.
3 bles were selected and model sparsity varied greatly.
4 he zymogen precursor protein C in a reaction greatly accelerated by the cofactor thrombomodulin.
5 led prevalence of GORD was 13.98% and varied greatly according to region (12.88% in Latin America and
6             The rNMP content of mtDNA varied greatly across different tissues and was defined by the
7                   Instead, this ratio varies greatly across HDRs from phylogenetically distinct plant
8 ze and preferred spatial frequency (SF) vary greatly across the primary visual cortex (V1), increasin
9 logy of the psychotic-affective spectrum may greatly advance biological determination of psychiatric
10                               These findings greatly advance the understanding of transcriptomic chan
11 l culture systems for prion propagation have greatly advanced molecular insights into prion biology,
12 nt of scientific CMOS (sCMOS) technology has greatly advanced optical microscopy for biomedical resea
13                           These studies have greatly advanced our understanding of how noxious mechan
14   We highlight recent achievements that have greatly advanced our understanding of pollen tube attrac
15 CGH) and whole-genome sequencing (WGS), have greatly advanced the identification of structural varian
16  genomes, in a site-specific manner has been greatly advanced through approaches that reduced the com
17 on-processed optoelectronics are believed to greatly affect device performance.
18 on of amorphous sucrose in food products can greatly affect the quality of foods.
19 oducts under atmospheric conditions and thus greatly affect their atmospheric transport and lifetime.
20                      Arctic science has been greatly affected by COVID-19.
21  release as a function of digestion time was greatly affected by oleogel structure: the extent of lip
22 in turn, a workflow's reproducibility can be greatly affected by the choices that are made with respe
23             Both enzyme and priming strategy greatly affected quantification of the exact same target
24 s, however, the different transcript leaders greatly affected translation.
25 ure in the Opa1 (+/-) photoreceptors was not greatly affected, but the mitochondria were enlarged and
26           It remains a global challenge that greatly affects the mobility, social participation and t
27 for prime-and-trap malaria vaccines and will greatly aid further investigations of cellular antimalar
28 s of the recently emerged SARS-CoV-2 will be greatly aided by the development and optimization of a s
29    Activities such as household cleaning can greatly alter the composition of air in indoor environme
30 rface reactivity and hazard potential can be greatly altered by chemical exposure history and NP surf
31                           Global warming has greatly altered winter snowfall patterns, and there is a
32 strate that core alkylation of porphyrinoids greatly alters the reactivity and spectroscopic properti
33              While tree mortality rates vary greatly Amazon-wide, on average trees are as likely to d
34 f the number of genes relevant to ASD differ greatly among research groups and clinical sequencing pa
35            While rates of decomposition vary greatly among woody species and spatially distinct habit
36 t, net VPS34CII-catalyzed PI3P production is greatly amplified by Rab5A, a small G protein of the Ras
37      Computational analysis reveals that the greatly amplified circular dichroism arises from exciton
38 c disease and precipitating factors may vary greatly and, therefore, the pathophysiology of AHF is hi
39 d isolates of Arthrobotrys oligospora varied greatly, as determined by the number of traps after expo
40  the amount of methylmercury produced varies greatly, as Hg methylation is dependent upon both the av
41  and monitoring of SARS-CoV-2 infections and greatly assist in the control of this outbreak.
42 with common pathogens, pan-family assays may greatly assist management of emerging pandemics through
43 targeting Ube2D1 did not affect charging but greatly attenuated chain elongation.
44 th CF (F508del/F508del) and CF mice showed a greatly attenuated or absent urinary HCO(3) (-)-excretin
45  Investigations of plant cell division would greatly benefit from a fast, inducible system.
46    Therefore, native mass spectrometry would greatly benefit from higher resolution approaches for in
47               Thus, these technologies would greatly benefit from methods to engineer arbitrary inten
48 rch on acute and chronic lung diseases would greatly benefit from reproducible availability of alveol
49 neering, and genetic disease prediction will greatly benefit from this resource.
50               Systemic mastocytosis (SM) has greatly benefited from the broad application of precisio
51 in ejection times from the ribosome can vary greatly between proteins due to differential electrostat
52 emic injury and inflammatory response differ greatly between the immature and adult brain.
53      By virtue, the cation exchange strategy greatly boosts the intrinsic and apparent activities of
54  We find that chromatin accessibility varies greatly by cell type and, more moderately, by brain regi
55 with CHD-coded health care encounters varied greatly by location, with 1.2 (EU), 10 (Massachusetts),
56                    While AVFA was decomposed greatly by Pseudoalteromonas atlantica and Alteromonas s
57 ical feature of concussion and is thought to greatly contribute to the classical symptoms of decrease
58  bacterial biofilms can be life-threatening, greatly decrease patient's quality of life, and are a su
59                    Transcripts of scyl-1 are greatly decreased in adr-1 mutants due to deficient RNA
60 mouse torpor, a fasting-induced state with a greatly decreased metabolic rate and a body temperature
61          We found that continuous P addition greatly decreased the concentrations of microbial residu
62 medium, the latter containing the secretome, greatly decreased the proinflammatory response of primar
63 ch reduces the replication rate of viral RNA greatly decreases the total tissue damage and virus burd
64 y, we found that an elevated PCO2 of 55 mmHg greatly delayed the permeation of a fluorescent glucose
65 ries with rapid population and income growth greatly depend on meat imports.
66 ngs reported in the literature is common but greatly depends on the investigator's prior knowledge of
67 st generations of nanozymes, which have been greatly developed in the past few years and exploited wi
68 ia behaviors close to axotomized motoneurons greatly differ from those within uninjured motor pools.
69 ures, a destabilizing H1N1 HA stalk mutation greatly diminishes viral replication and pathogenicity i
70 rrant systemic circulation of bile acids can greatly disrupt metabolic homeostasis.
71  regulators; perturbing the levels of either greatly disrupts genome-wide folding as assayed by chrom
72 cell, the Pb I octahedra concurrently become greatly distorted, with one of the I Pb I angles approac
73 hemical, and biodistribution properties that greatly enhance bioimaging performance.
74 disrupt these intrinsic ACD-NTR interactions greatly enhance chaperone activity toward tau.
75 s, including use of covariate stability, can greatly enhance data interpretation and confidence in va
76 hough DCs have specific characteristics that greatly enhance HIV-1 transmission, it is becoming evide
77 ps from transcription factors to genes would greatly enhance our understanding of transcriptional dyn
78 y using integrated TIMES signal (i-TIMES) to greatly enhance the accuracy and reproducibility of the
79 onstrates that coculturing MSCs with ACs can greatly enhance the chondrogenicity of the overall cell
80 onomers, where certain designs were found to greatly enhance the stability of DNA origami.
81 allographic and spectroscopic analysis, will greatly enhance understanding of luminescent molecules a
82               Notably, humans appear to have greatly enhanced and possibly unique HC-mediated capacit
83                  The rate of ligation can be greatly enhanced by employing a 3'-amino group at the 3'
84 understanding of protein complex function is greatly enhanced by insights from its 3-dimensional stru
85 in MS instrumentation and MS/MS methods have greatly enhanced capabilities for the analysis of large
86 copy and finite element analysis reveal that greatly enhanced chemical activity and structural robust
87 rably from Brownian motion, as revealed by a greatly enhanced diffusion coefficient(3-10) and non-Gau
88 eposition approach to TLG growth that yields greatly enhanced fraction and size of ABC domains.
89 A-4 (a checkpoint inhibitor drug) results in greatly enhanced immune response and significantly longe
90  a downstream phosphorylation target of Ik2, greatly enhanced the mutant CHMP2B phenotype.
91                             Conclusion: With greatly enhanced tumor uptake and tumor-to-kidney absorb
92 es-induced photoinhibitory NPQ component was greatly enhanced upon Asc deficiency, both under photomi
93 anding of the many functions of NOM could be greatly enhanced.
94 e plastid division factor PLASTID DIVISION 1 greatly enhances carotenoid accumulation.
95 f a ternary SPIN90-Arp2/3-mDia1 complex that greatly enhances filament nucleation.
96  minimally invasive, and for the first time, greatly enhances our ability to measure neonate turtle s
97 e that the single-site catalyst Pt(1)/CeO(2) greatly enhances the selectivity of cyclization and arom
98 side of hospitals and clinical laboratories, greatly enhancing diagnostic capabilities.
99 ing both primary- and high-order structures, greatly enhancing our capabilities of designing organic
100 , high temperature, and in saline solutions, greatly enhancing the efficiency and functionality of ap
101 hermodynamics-based approach is proposed for greatly enhancing the sensitivity of detection with non-
102 oduce substantial clinical benefit but would greatly exceed conventional cost-effectiveness threshold
103      Variation in nonsteady-state efficiency greatly exceeded that at steady state, suggesting a new
104                 Together, these technologies greatly expand our ability to study and understand speci
105                               These findings greatly expand our understanding of the types of immune
106      In this issue of the JCI, Ravell et al. greatly expand the clinical picture.
107 t of high-frequency multivariate data, which greatly expand the fundamentally limited and coarse data
108 ique ecological role for the group involving greatly expanded energy and resource utilization, with c
109 biquitin ligase components, which comprise a greatly expanded gene family in C. elegans Here we use c
110 driver mutations in protein-coding genes has greatly expanded in the past decade.
111                            These new genomes greatly expanded the known pangenomes of many oral clade
112                 This will be instrumental in greatly expanding our knowledge of the origins and varia
113  these techniques provide powerful tools for greatly expanding the protein engineering toolkit.
114 he posterior articular facet of the coracoid greatly expands anteroventrally during development.
115 ant bacterium Pseudomonas putida KT2440 that greatly expands computable predictions of its metabolic
116 mical modification of phage libraries, which greatly expands the chemical space amenable to phage dis
117                                         LUCS greatly expands the designable structure space and offer
118 threshold optimization and network inference greatly expands the high-confidence TF network map in bo
119  into hierarchical macroscopic materials can greatly extend their practical applications.
120 odels that mimic the in vivo environment can greatly facilitate and support criticality assessment of
121             A high-throughput platform would greatly facilitate coronavirus disease 2019 (COVID-19) s
122 urce for the analysis of human RBPs and will greatly facilitate future analysis of the various biolog
123 d with the ordered crystalline COF structure greatly facilitate lithium ion storage via reversible re
124 Such an easy-operating and robust tool would greatly facilitate O-glycosylation analysis on single pr
125                  Overall, our technology can greatly facilitate rapid, sensitive, and quantitative an
126                         This new method will greatly facilitate researchers to jointly study transcri
127 nd utilization of genetic materials and will greatly facilitate the dissection of genotype-by-environ
128 ses of next-generation sequencing technology greatly facilitate the extensive molecular characterizat
129 pplicable compounds and human proteins would greatly facilitate their therapeutic use.
130 nervous system (CNS), and this work has been greatly facilitated by microglial depletion paradigms.
131 ion patterns, while their detection has been greatly facilitated by recent achievements in next-gener
132 anization and function of neural circuits is greatly facilitated by viral tools that spread transsyna
133 t can infect the model host Arabidopsis, has greatly facilitated transgenic analyses of genes importa
134 dow of fluorescent heptamethine cyanine dyes greatly facilitates biological imaging because there is
135  under the working CO(2)RR conditions, which greatly facilitates the CO(2) to methane conversion.
136 we introduce RepeatModeler2, a pipeline that greatly facilitates this process.
137 -renal disease would be predicted to benefit greatly from CVD risk factor intervention.
138                         Current diets differ greatly from EAT-Lancet targets.
139  The study of animal behaviour could benefit greatly from generally expanding to incorporate these ne
140  in molecular collisions(2-5), however, have greatly hampered the engineering of low-entropy molecula
141 contrast, PML pathogenesis research has been greatly hindered because of the lack of an animal model.
142 nimal models for hepatitis C virus (HCV) has greatly hindered the development of effective vaccines.
143              Knots in the human genome would greatly impact diverse cellular processes ranging from t
144                                     Diet can greatly impact health, while caloric restriction and fas
145         The metabolic state of the brain can greatly impact neurologic function.
146 porated materials and structures as they can greatly impact the bandwidth, frequency resolution, sign
147 of these crucial phenotypic traits that have greatly impacted insect behavior, physiology, and evolut
148  sinks of molecular oxygen in the oceans has greatly impacted the composition of Earth's atmosphere s
149            Up to now, this strategy has been greatly impaired in resource-poor countries, because scr
150 al challenges posed by these properties have greatly impeded our understanding of sHSP structure and
151 These results show that introgressed QTL can greatly improve broad-spectrum disease resistance while
152 s, or instead, gain-of-function enzymes that greatly improve DNA translocation efficiency and nucleos
153 pecific methods for RLP quantification would greatly improve our understanding of their biology and r
154 ctions; thus, reducing this uncertainty will greatly improve outage risk management.
155 on assessment and monitoring of sharks could greatly improve temporal and spatial data used for manag
156 ardware using emerging nanoscale devices can greatly improve the efficiency of bionic medical machine
157 ion of allergenic ingredients in foods would greatly improve the health and quality of life of food a
158      "Nonfouling" polymer brush surfaces can greatly improve the performance of in vitro diagnostic (
159 ratory defect of mac1Delta/Delta mutants was greatly improved by a sod1Delta/Delta mutation, demonstr
160 ional outcome of patients with stroke can be greatly improved by optimizing IVT to EVT times.
161               Computational science has been greatly improved by the use of containers for packaging
162 specific capacity of ~190 mAh g(-1) and show greatly improved cell performances under a high charge v
163  and 1.0) alloys and the magnetostriction is greatly improved from 39 ppm (x = 0, as-cast) to 103 ppm
164 s environment inside ion-flow channels, with greatly improved mass transfer and turnover frequency as
165  biologic, an IL-2/CD25 fusion protein, with greatly improved pharmacokinetics and pharmacodynamics w
166 ific capacity (963 C g(-1) at 0.1 mV s(-1)), greatly improved rate capability (from 4.4% to 40.2% at
167                         The PB film exhibits greatly improved reproducibility and stability as compar
168 ive CIA toward muscle-type nAChRs but showed greatly improved resistance to degradation in human seru
169                                         With greatly improved spectral annotation, coupled with the s
170 l chemical reaction between nylon and MAHgEO greatly improved the adhesion of these dissimilar materi
171 nucleic acid amplification tests (NAATs) has greatly improved the assay sensitivity and specificity,
172 plication of exome and genome sequencing has greatly improved the rate of genetic diagnosis for CHD b
173                        This design renders a greatly improved theranostic nanomedicine for efficient
174 ty of the LSCs after TPP treatments has been greatly improved, even after long-term (30 days) immersi
175 ing cells into a narrow linear configuration greatly improves the efficiency of cell growth and chrom
176 nd co-evolutionary restraints to AWSEM-Suite greatly improves the predictive power of pure AWSEM stru
177 The development of a one-pot, washless assay greatly improves usability compared to traditional immun
178 a families and an additional subfamily, thus greatly improving taxonomic coverage.
179 d neuronal subtypes that, although differing greatly in morphology and connectivity, converge to indi
180 oreover, we find that S. pombe isolates vary greatly in their ability to make haploid spores, with so
181 ng this technology in clinical settings will greatly increase capacity to generate clinical-grade pep
182 r early state disease detection, which would greatly increase patient survival rates.
183 y in individuals of recent African ancestry, greatly increase risk of multiple types of kidney diseas
184 ly required for T6SS assembly, although they greatly increase secretion efficiency.
185 y sensitive to increased temperatures, which greatly increase substrate load on the ubiquitin-proteas
186 o different functional proteoforms, and thus greatly increase the functional diversity of protein var
187 brae and a specialized first dorsal vertebra greatly increase the vertical range of motion of the nec
188 latory oligonucleotides that, in some cases, greatly increase their potency to activate inflammatory
189 sequently, Arctic ecosystems are expected to greatly increase their VOC emissions with ongoing climat
190 roliferative disorder in the bone marrow was greatly increased by centralized biopsy assessment.
191                  Management success could be greatly increased by identifying and exploiting individu
192               Patient HF samples also showed greatly increased CaMKIIdelta expression, especially for
193 osities, setback, and final viscosities were greatly increased compared to those of the samples proce
194       The uptake to acidic aerosol particles greatly increased for a binary mixture of glyoxal and pi
195     Slc26a6 mRNA and protein expression were greatly increased in the intestine of mice with CKD.
196                     Loss of Tfr cells led to greatly increased nonspecific IgE levels, showing that T
197 V) subverts host innate immune signaling has greatly increased over the past decade.
198  in 1978, recognition of these disorders has greatly increased over the past several decades.
199 ions have reached the market, resulting in a greatly increased range of treatment options for patient
200 pe II interferon signaling pathway, and this greatly increased secondary bacterial co-infection.
201 uglycemic clamp revealed that VDR activation greatly increased the glucose infusion rate, while hepat
202                                     This has greatly increased the number of large protein-protein cl
203   In a follow-up test phase, a simple prompt greatly increased the rate at which the younger children
204  High-throughput screens powered by NGS have greatly increased the rate of variant functionalization,
205 ariants in 7 genes that were associated with greatly increased vulnerability to clonal haematopoiesis
206 ole as noncanonical splicing regulators were greatly increased, most notably, rpl10a When the levels
207  demand for high-precision X-ray mirrors has greatly increased.
208                                  Thus, LT-FH greatly increases association power when family history
209 stances much larger than qubit length scales greatly increases connectivity and is an important step
210  affinity for DNA but deletion of the C-tail greatly increases Mtf1's DNA binding affinity.
211 tion for folded and monomeric RNA pools thus greatly increases the frequency of functional RNAs from
212                                    This work greatly increases the number of nonstoichiometric MXenes
213  mounted manually, our microfluidic approach greatly increases throughput.
214 dation products across their elution window, greatly increasing method development time and reducing
215 NA and RNA with single nucleotide precision, greatly increasing the fractions of rare alleles and, en
216 i1 and Lsi2 while the addition of Si further greatly induced their expression under Buta toxicity.
217 pressed in WT Mtb and that its expression is greatly induced upon depletion of clpC1 or clpP2 Remarka
218 hese topics are nuanced, taken together they greatly influence the clinical utility of testing.
219  genetic instrument (maternal or fetal) will greatly influence the interpretation of the results.
220 g of metal nanoparticle surfaces is known to greatly influence their catalytic, electronic transport,
221 time it took participants to find plants was greatly influenced by target concealment.
222 lity of hydrolysate-stabilized emulsions was greatly influenced by their physical stability.
223 mmune response during C. difficile infection greatly influences disease severity.
224 ion orchestrates many cellular processes and greatly influences key disease mechanisms.
225 the choice of gradient fractions to sequence greatly influences method performance.
226 the Spike protein interaction surface, which greatly influences Spike protein binding mode.
227   Our results provide evidence that activity greatly influences the probability of attacks and that f
228  this initial set of questions and will also greatly inform our understanding of the contributions of
229 hanisms of such functional diversity will be greatly informed by understanding the cell-type-specific
230 elination is highly active in young mice and greatly inhibited in aged mice, coinciding with spatial
231          The overall shortage of natural gas greatly jeopardized the air quality benefits of the coal
232                    Dams are not predicted to greatly limit future range shifts for most species (i.e.
233      Despite such minuscule gradients (which greatly limit the possible influence of the well-underst
234                However, their development is greatly limited by the inferior performance under high v
235 ght from current empirical investigations is greatly limited by the lack of methodologies that simult
236 xpertise to fabricate and operate, which has greatly limited implementation in most proteomic laborat
237 viruses in general populations worldwide has greatly limited their clinical utility.
238 s solubility and low dissolution rate, which greatly limits its application, especially in beverages.
239  are unstable in low Mg(2+) conditions; this greatly limits their utility in physiological settings.
240  of 3D/2D hybrid PeLED is only 7.4% which is greatly lower than that of 3D PeLED (150.4%).
241 lth has created new opportunities that could greatly modernize surveillance if coordinated in a pragm
242 ance of others within our space also depends greatly on our social relationships with them.
243 ntitative evidence that defective proviruses greatly outnumber intact proviruses (by >12.5 fold).
244  To handle the increased workload, LV growth greatly outpaces that of the RV during postnatal stages.
245 slational regulation had until recently been greatly overlooked.
246  of striated muscle contraction has advanced greatly, particularly via cryo-electron microscopy data.
247 ivity did not affect nucleotide binding, but greatly perturbed the ability of bound nucleotide to inh
248                          This process may be greatly potentiated by the presence of amphipathic compo
249 , we found that IRF3-knockout (KO) mice were greatly protected from sepsis in a clinically relevant v
250 enetic diseases within the same pathway vary greatly, ranging from muscular dystrophy to spastic para
251 lapse of a flowering stalk, for example, can greatly reduce plant fitness if it leads to 'incorrect'
252 ligand during the C-H activation process can greatly reduce the kinetic barrier, a unique case of two
253  potentially life-threatening disease, could greatly reduce the threat posed by its etiologic agent,
254           The DeltacsrA mutant strains had a greatly reduced ability to kill Galleria mellonella larv
255 ongation is promoted, whereas root growth is greatly reduced as a result of changes in hormone transp
256  deletion of ETV4, using CRISPR/Cas9, led to greatly reduced ER binding at the majority of loci norma
257 toylamino-3-pyrrolidino-1-propanol (EtDO-P4) greatly reduced GSL and monosialotetrahexosylganglioside
258 ize heme or protoporphyrin IX for growth was greatly reduced in a DeltauroS mutant.
259 er but not the reverse, (3) number acuity is greatly reduced in stimuli controlled for perceived area
260          This need for multiple infection is greatly reduced in the natural host.
261 utput of that group of transcripts will have greatly reduced inferential uncertainty, thus allowing m
262 scripts and chromatin features, as well as a greatly reduced level of beta-catenin signaling.
263  Burkitt's lymphoma, homozygous Mnt deletion greatly reduced lymphoma incidence by enhancing apoptosi
264 ontrast, sustained mesoaccumbal inactivation greatly reduced motivation for performing a motivation-b
265 ss through cryptobenthic fish assemblages is greatly reduced on Earth's hottest coral reefs.
266                          In addition, PG-CAT greatly reduced the concentration of inflammatory cytoki
267 -carbonitrile (PCN) in wild-type mice, which greatly reduced the severity of TcdA/B-induced damage an
268 ndeed, the extra insects fed to urban chicks greatly reduced the significant differences in survival
269  recent tariff wars and border closures have greatly reduced the virtual water embodied in American e
270          Reagent and sample consumptions are greatly reduced to mL and mg levels, compared with those
271 nd the energy-dependent timing jitter can be greatly reduced to the 10 fs level.
272 d from knockdown of PRP1 and PRP2 in that it greatly reduced viability of hairy root tumors.
273 rown in the valley and maize cultivation was greatly reduced.
274 ormal telegraph noise can be utilised, which greatly reduces device selectivity and offers much great
275 an stomach, we show that H. pylori infection greatly reduces NEIL2 expression.
276 toichiometry of I(-) transport to 1:1, which greatly reduces the driving force.
277        Intractable or recurrent chronic itch greatly reduces the patients' QOL and impairs their dail
278 ransplants by at least 447 over 2 years, and greatly reduces waiting times of KPDP candidates.
279 guided, can be used for these sRNA-Seq data, greatly reducing the ambiguity of mapping reads.
280  representation of cartilage properties thus greatly reducing the impact of the information gathered
281  grafts for transplantation every year, thus greatly reducing the nationwide disparity between supply
282  posterolateral cerebellum has also expanded greatly relative to non-human primates and has an organi
283 ering the analysis of suppressed species and greatly restraining quantitative analysis.
284                                         This greatly simplifies the experimental exploration of quant
285     Significantly, this separation technique greatly simplifies the exploration of block copolymer ph
286 lts indicate that 16S V1-V2 metagenomics can greatly simplify diagnosis and accelerate the discovery
287  nature of experimental research has changed greatly since the Belmont Report.
288               A strong activator (Gal4-VP16) greatly stimulated reversible binding of individual RNAp
289 ort here that in vitro osteoclastogenesis is greatly suppressed by soluble extracts of PRF membranes
290 ese novel drug formulations could contribute greatly to HIV treatment and prevention efforts, their l
291 ng itself, nor seawater sulfate, contributed greatly to stomatal closure.
292 t of DNA damage on human physiology has been greatly underestimated.
293 ally in recent years, mosquito taste remains greatly understudied.
294                               However, it is greatly unknown how the IDPs are involved in DDR.
295            The depletion of PHF8 or PKCalpha greatly up-regulated PTEN expression, which could be res
296 orphyrins were dramatically altered and gave greatly weakened absorptions.
297           In some cases, growth-rates varied greatly with stressor concentration even when lag remain
298        The role of tRNA modifications varies greatly with the specific modification within a given tR
299 ermined mostly by molecular size, correlates greatly with time and slope to reach peak intensity: sma
300 inery, and anatomical features that can vary greatly within and among species.

 
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