ライフサイエンスコーパス: greatly expand

1 odermal progenitor cells (cPE cells), can be greatly expanded.

2 polyomavirus BK (BKV) genomic diversity has greatly expanded.

3 thogens and secreted into the host cells has greatly expanded.

4 This map greatly expanded ABA core signaling but was still manage

5 s and predict network architectures has been greatly expanded, accelerating interest in systems biolo

6 (application programmers interface) we have greatly expanded access to MG-RAST data, as well as prov

7 s for unnatural amino acid incorporation has greatly expanded access to nonstandard amino acids by ex

8 ithms and scalable expression platforms have greatly expanded access to the chemical repertoire of fu

9 This method has the promise to greatly expand ANA testing in clinical settings for init

10 ships between chromosomal segments that have greatly expanded and contracted in salamander and chicke

11 vessels in the hypoxia-exposed animals were greatly expanded and some contained large cuboidal cells

12 initiated through interactions at DIS may be greatly expanded and stabilized by formation of an inter

13 ventitia of normal arteries, their number is greatly expanded and their distribution changed in human

14 gnificantly from that of rodents, exhibiting greatly expanded and uniquely distributed cortical and s

15 population of atypical memory B cells (MBCs) greatly expands and these MBCs show attenuation of B cel

16 Human genome sequencing efforts have greatly expanded, and a plethora of missense variants id

17 he posterior articular facet of the coracoid greatly expands anteroventrally during development.

18 rs T cell activation and proliferation, thus greatly expanding antigen-specific clones.

19 nt of patients entering treatment trials has greatly expanded as clinical researchers and pharmaceuti

20 embryo, generating an embryo consisting of a greatly expanded, but correctly patterned, APD.

21 The number of lncRNA genes has recently been greatly expanded by our group to triple the number of pr

22 dium of RNA-binding proteins (RBPs) has been greatly expanded by the development of RNA-interactome c

23 s, our knowledge of gene regulation has been greatly expanded by the discovery of microRNAs (miRNAs).

24 This packing results in a greatly expanded cavity, which is capped at either end b

25 acrophages cultured in the presence of IL-34 greatly expanded CD8+ and CD4+ FOXP3+ Tregs, with a supe

26 ased efficacy and overcoming resistance, and greatly expanded clinical development of pan-HDAC-inhibi

27 ant bacterium Pseudomonas putida KT2440 that greatly expands computable predictions of its metabolic

28 wn characteristic genome size, GC ratio, and greatly expanded core gene content, making the genomic d

29 pneumococcal and rotavirus infections while greatly expanding coverage of existing vaccines.

30 into the existing projects of other groups, greatly expanding current engineering capacities.

31 This work greatly expands doping chemistry for tailoring the struc

32 tool for fluorescently labeled biomolecules greatly expands dynamic range and enables retrospective

33 he current 'holobiont' concept framework has greatly expanded eco-evolutionary and functional underst

34 ique ecological role for the group involving greatly expanded energy and resource utilization, with c

35 training institutions into universities and greatly expanded enrolment of health professionals.

36 biquitin ligase components, which comprise a greatly expanded gene family in C. elegans Here we use c

37 ing alleles also increase BE and/or EA risk, greatly expanding gene discovery for these traits.

38 first launching the website in 2011, we have greatly expanded HaploReg, increasing the number of chro

39 e digitization efforts have the potential to greatly expand herbarium-based phenological research, bu

40 Xenbase has also greatly expanded image content for figures published in

41 xpressing naive T cells (termed TNreg cells) greatly expand in vitro.

42 Myeloid-derived suppressor cells (MDSCs) are greatly expanded in cancer patients and tumor-bearing mi

43 ed to as p-ERK1/2-refractory cells) that was greatly expanded in HIV-1-infected adults.

44 ver, FcRL6 expression among T lymphocytes is greatly expanded in human immunodeficiency virus type 1

45 lopmental stages, although morphogenesis was greatly expanded in humans.

46 The subventricular zone (SVZ) is greatly expanded in primates with gyrencephalic cortices

47 d the colonic crypt proliferative zone being greatly expanded in slc26a3-null mice.

48 irus infection in normal mice, NK cells were greatly expanded in the draining LN, were not replicatin

49 that typically represent face and tongue are greatly expanded in the left hemisphere.

50 driver mutations in protein-coding genes has greatly expanded in the past decade.

51 Although our knowledge of aging has greatly expanded in the past decades, it remains elusive

52 Options for artificial nutrition have greatly expanded in the past few decades, but have conco

53 and the causes and consequences of ENSO have greatly expanded in the past few years.

54 The stable structure is greatly expanded in the Sc37 conformation to encompass t

55 ed from the marginal zone at 6-12 h, but was greatly expanded in the T cell areas, and by 24-48 h, La

56 DR cell population was greatly expanded in the Tr(-/-)Mdr2(-/-) versus Mdr2(-/-

57 Indeed, dual-kappa B cells are greatly expanded into effector B cell subsets in some au

58 respiratory disease will likewise require a greatly expanded investment in pulmonary, critical care,

59 rates that form mixed disulfides with ERdj5, greatly expanding its client repertoire.

60 urpose, direct regulator of gene expression, greatly expanding its role in coordinating developmental

61 erfere with subsequent tetrodotoxin binding, greatly expands its scope as a reagent for probing sodiu

62 16 release, the pipeline's functionality has greatly expanded, its computational efficiency has impro

63 lex than previously recognized and provide a greatly expanded knowledge base for studies to understan

64 the Hofmann House, where it centralized its greatly expanded literary activity including abstracts a

65 mmunity-activating RPP1 homologs and possess greatly expanded LRR domains.

66 Using this greatly expanded metric, we show that mutants defective

67 and manipulate these pathways, this resource greatly expands molecular insight into neuronal regulati

68 nitive abilities are usually attributed to a greatly expanded neocortex, which has been described as

69 y 551 Myr ago, molybdenum contents reflect a greatly expanded oceanic reservoir due to oxygenation of

70 These data greatly expand on the known significant strain-to-strain

71 agnosis and treatment for pituitary adenomas greatly expand our ability to care for affected patients

72 t to automate the search process, which will greatly expand our ability to identify, consider, and te

73 Together, these technologies greatly expand our ability to study and understand speci

74 s assays based on high-throughput sequencing greatly expand our ability to understand the genome.

75 microscopy studies of microbial S-layers and greatly expand our molecular view of S-layer dimensions,

76 molecular activity across sequence space can greatly expand our understanding of RNA sequence-functio

77 cumbed to their disease has the potential to greatly expand our understanding of the most lethal stag

78 These findings greatly expand our understanding of the types of immune

79 Emerging technologies have greatly expanded our ability to detect, characterize, an

80 Highly multiplex DNA sequencers have greatly expanded our ability to survey human genomes for

81 dvances in CRISPR based biotechnologies have greatly expanded our capabilities to repurpose CRISPR fo

82 higher resolution and throughput, which has greatly expanded our current understanding of G-quadrupl

83 past several decades, numerous studies have greatly expanded our knowledge about how microtubule org

84 visualize and manipulate glia in vivo, have greatly expanded our knowledge of glial biology and neur

85 is lower in captive than in wild devils, has greatly expanded our knowledge of gut-associated viruses

86 wever, a number of recent breakthroughs have greatly expanded our knowledge of how aspects of cellula

87 While in vitro studies have greatly expanded our knowledge of mitochondrial dynamics

88 tically engineered mouse models (GEMMs) have greatly expanded our knowledge of pancreatic ductal aden

89 sis of genomic DNA from the environment, has greatly expanded our knowledge of the diversity of micro

90 plication of small-molecule inhibitors, have greatly expanded our knowledge of the functions, targets

91 periments and next-generation sequencing has greatly expanded our knowledge of the genomic mutation r

92 together, the studies summarized herein have greatly expanded our knowledge of the molecular biology

93 with viral glycoprotein surface antigens has greatly expanded our knowledge of the sites of vulnerabi

94 Reports from the last two years have greatly expanded our knowledge of these proteins and sug

95 es has been challenging, recent progress has greatly expanded our repertoire of powerful techniques m

96 The complete genome has also greatly expanded our understanding of ET-743 production

97 rious filoviruses, but recent outbreaks have greatly expanded our understanding of filovirus immune r

98 However, recent reports have greatly expanded our understanding of GILT's function.

99 l sequencing of individual human genomes has greatly expanded our understanding of human genetic vari

100 l analysis of the critical host response has greatly expanded our understanding of infectious disease

101 These studies have greatly expanded our understanding of mechanisms underly

102 r visualizing dynamic cellular activity have greatly expanded our understanding of the brain.

103 Intense research has greatly expanded our understanding of the pathobiology o

104 Although metagenomic approaches have greatly expanded our understanding of the prokaryotic vi

105 Recent studies have greatly expanded our understanding of the regulation of

106 Recent advances have greatly expanded our understanding of these receptors as

107 man volunteers, and clinical populations are greatly expanding our knowledge about the neural basis o

108 e sex chromosomes at the genomic level, thus greatly expanding our knowledge of reptilian and vertebr

109 This will be instrumental in greatly expanding our knowledge of the origins and varia

110 etter than known OSDAs for zeolite beta, and greatly expanding our previous list of 152 such predicte

111 e been identified, including desnutrin/ATGL, greatly expanding our understanding of adipocyte lipolys

112 shering in a new era of risk assessment that greatly expands our ability to evaluate chemical safety

113 abrication with high-throughput DNA curtains greatly expands our capability to interrogate complex bi

114 plex way in which NF-kappaB is regulated and greatly expands our understanding of how MCV so effectiv

115 poorly characterized OPN3 and a pathway that greatly expands our understanding of melanocyte and skin

116 , yielding a new three-level annotation that greatly expands our understanding of prokaryotic genomes

117 Our analysis greatly expands our understanding of the breadth of the

118 We now report that Treg greatly expand over effector T cells in d3tx mice and ad

119 they achieve their differentiated state has greatly expanded over the past 2 decades.

120 A greatly expanded P. glauca composite linkage map was gen

121 jor enhancements and new functions: it has a greatly expanded phylogenetic marker database and can an

122 tes were predominantly CD4(+) and included a greatly expanded population of CD3(+)CD4(+)CD25(+)Foxp3(

123 t-based covalent ligand discovery provides a greatly expanded portrait of the ligandable proteome and

124 indicate that antenna-reactor complexes may greatly expand possibilities for developing designer pho

125 , decreased visual cortex alpha power, and a greatly expanded primary visual cortex (V1) functional c

126 anslational modifications (PTMs) of proteins greatly expand proteome diversity, increase functionalit

127 space-based imagery but current capabilities greatly expand scientific possibilities.

128 Recent literature has greatly expanded scientific knowledge of unconventional

129 ale for much of the last 2,000 years using a greatly expanded set of proxy data for decadal-to-centen

130 ith our previous format, the new assays show greatly expanded signal dynamic ranges.

131 f annotated lncRNAs in mammalian genomes has greatly expanded, studying lncRNA function has been a ch

132 These novel transgenic lines greatly expand the ability to monitor and manipulate neu

133 mbined with readily available reagents, will greatly expand the access and availability of tailored p

134 caffold-based antibody engineering and could greatly expand the antibody functional repertoire in the

135 These results greatly expand the application of dipole engineering to

136 opportunity that, if widely embraced, could greatly expand the application of imaging to improve cli

137 fficiency and narrow beatnote linewidth will greatly expand the applications of quantum cascade laser

138 These findings greatly expand the c-di-AMP signaling repertoire and rev

139 Together, these results greatly expand the capabilities of KFP and are suitable

140 In this issue of the JCI, Ravell et al. greatly expand the clinical picture.

141 Here we greatly expand the coiled-coil toolkit by measuring the

142 In this study, we greatly expand the collection of natural isolates and ch

143 d the use of multiple analytical methods can greatly expand the comprehensiveness of shotgun proteomi

144 pecific autonomy of presynaptic function can greatly expand the computational prowess of central axon

145 These results greatly expand the current concept about anchoring mecha

146 Our results greatly expand the current knowledge of HKR structure, o

147 hod for preparing DNA for amplification will greatly expand the diagnostic applications of nucleic ac

148 These observations greatly expand the distribution of possible unidentified

149 In addition, these genomes greatly expand the diversity of existing genomic context

150 These findings greatly expand the diversity of the key marker gene for

151 sequences of these 14 new trichomonasviruses greatly expand the existing data set for members of this

152 These findings greatly expand the functional and regulatory complexity

153 signaling nodes (GSK3, FoxO, mTORC1), which greatly expand the functional repertoire of AKT, and the

154 t of high-frequency multivariate data, which greatly expand the fundamentally limited and coarse data

155 ute to biologically relevant gene expression greatly expand the genome space that must be considered

156 rge number of TRIM proteins, our results may greatly expand the identified SUMO E3s.

157 proposed sensitivity to tissue structure may greatly expand the information available with convention

158 opod species analyzed.IMPORTANCE Our results greatly expand the knowledge of EVE abundance, diversity

159 These studies should greatly expand the landscapes of protein structure-funct

160 Collectively, our findings greatly expand the limited tool kit available to study p

161 ly, play extranuclear, nongenomic roles that greatly expand the multiple mechanisms employed for thei

162 In addition, these studies greatly expand the number of known thiostrepton analogue

163 Here we greatly expand the number of known W-linked genes and as

164 lecommunication technologies, the scheme can greatly expand the number of users in quantum networks a

165 lls and supporting cells, and it will likely greatly expand the potential applications for inner ear

166 mains from cellulose-degrading bacteria, can greatly expand the range of Ags for this DC-targeting va

167 sibility analysis using patient samples will greatly expand the range of translational research and p

168 ed by the IPCC A2 and B1 emissions scenarios greatly expand the range over which the pathogen can sur

169 Such a synthesis would also greatly expand the relevance of model systems for studie

170 ation sequencing in comparative genomics and greatly expand the repertoire of available primate codin

171 Together, these results greatly expand the repertoire of candidate taste and phe

172 ngth liver-enriched transcription factor and greatly expand the repertoire of HNF4alpha-binding seque

173 Altogether, these new 3' UTR annotations greatly expand the scope of post-transcriptional regulat

174 Our present results greatly expand the spectrum of functionally characterize

175 These studies greatly expand the structural and functional repertoire

176 en by specific non-covalent interactions can greatly expand the structural and functional space of su

177 Post-translational modifications (PTMs) greatly expand the structures and functions of proteins

178 The results presented herein greatly expand the suite of ABPP probes for profiling P4

179 urized enzyme replicas with the potential to greatly expand the technological utility of hydrogen per

180 Although lncRNAs greatly expand the transcriptional repertoire, we have a

181 These results greatly expand the universe of target cancer antigens an

182 al reagent or substrate has the potential to greatly expand the use of more energy efficient paired e

183 The methods introduced here greatly expand the utility of NMR in the structural char

184 Overall, these strategies are expected to greatly expand the utility of self-immolative polymers b

185 We have greatly expanded the Alternative Splicing Annotation Pro

186 repeats (CRISPR)/Cas12a (Cpf1) system, have greatly expanded the applicability of editing the genome

187 resonance-based methods which have together greatly expanded the array of pathogens identified, incr

188 Mass cytometry (CyTOF) has greatly expanded the capability of cytometry.

189 We have greatly expanded the data sets available on the most rec

190 Such studies have greatly expanded the knowledge of the evolution and dive

191 These new genomes greatly expanded the known pangenomes of many oral clade

192 nthesis of polymer-grafted nanocrystals have greatly expanded the library of accessible superlattice

193 New evidence-based treatments have greatly expanded the medical and surgical management opt

194 of a commercial serologic test for ZIKV has greatly expanded the national capacity for such testing,

195 udies and large-scale proteomics efforts has greatly expanded the quantity of available protein infor

196 Thus, we have greatly expanded the range of carbocyclic nucleotide ana

197 Recent studies have greatly expanded the range of microorganisms known to fu

198 oth methodology and computational power have greatly expanded the scope of problems that VB theory ca

199 (CRISPR)-Cas9 system for genome editing has greatly expanded the toolbox for mammalian genetics, ena

200 In vivo imaging advances have greatly expanded the use of animal cancer models.

201 umors or desired cell populations while also greatly expanding the applicability of the intein-based

202 s in the white matter regions of the tissue, greatly expanding the chemical coverage and the potentia

203 fects approximately 95% of eukaryotic genes, greatly expanding the coding capacity of complex genomes

204 of an array of alkyl electrophiles, thereby greatly expanding the diversity of target molecules that

205 regulatory network across the transcriptome, greatly expanding the functional genetic information in

206 s of scientific and agricultural importance, greatly expanding the known repertoire of stable protein

207 While emerging studies are greatly expanding the known universe of RNA-binding prot

208 quent cycles of immunostaining (>10 cycles), greatly expanding the multiplexing capability.

209 d of functional genomics in Dictyostelium by greatly expanding the mutation spectrum relative to othe

210 n-responsive Signaling-SSPs were identified, greatly expanding the number of SSP gene families potent

211 o samples from 10 countries and territories, greatly expanding the observed viral genetic diversity f

212 oonTag enables dual readouts of translation, greatly expanding the possibilities to interrogate compl

213 monitoring libraries during selection, thus greatly expanding the power of these systems.

214 these techniques provide powerful tools for greatly expanding the protein engineering toolkit.

215 gh alternative splicing, which is capable of greatly expanding the protein repertoire by generating,

216 l studies and defining its limitations, thus greatly expanding the range and precision of the formal

217 from various extended building blocks, thus greatly expanding the range of applicable molecules.

218 d to entirely different erythrocyte ligands, greatly expanding the range of erythrocytes that P. falc

219 isting split-GAL4 and split-LexA lines, thus greatly expanding the range of possible advanced interse

220 uces the overall energy requirements thereby greatly expanding the range of semiconductors that can b

221 be introduced in a similar fashion, thereby greatly expanding the range of single-molecule covalent

222 d to non-liposome-forming compounds, thereby greatly expanding the range of structures that can be te

223 traight- and branched-chain alpha-ketoacids, greatly expanding the range of substrates previously kno

224 opportunity for facilitating drug design by greatly expanding the repertoire of available drug targe

225 lly and spatially distinct pathways, thereby greatly expanding the repertoire of cellular and network

226 aints can be decoded from genetic variation, greatly expanding the repertoire of transmembrane protei

227 onstraints of natural nucleic acids, thereby greatly expanding the structural vocabulary of nucleic a

228 ghput sequencing has opened a new field that greatly expands the amount of in vitro and in vivo RNA s

229 The technique greatly expands the applicability of DOSY D-FW analysis

230 ield of vibration energy harvesting but also greatly expands the applicability of TENGs.

231 recent single cell and bulk RNA-seq datasets greatly expands the available gene expression informatio

232 e still unclear, but this deep recombination greatly expands the breadth of virus evolution and confo

233 ased on optical tweezing is presented, which greatly expands the capabilities of this technique.

234 e results reveal a degree of complexity that greatly expands the capacity of the system to encode bit

235 in cofermentations with sucrose and glucose greatly expands the capacity of yeast to use plant cell

236 mical modification of phage libraries, which greatly expands the chemical space amenable to phage dis

237 o the synthesis of monolayer carbon networks greatly expands the chemistry, morphology, and size of c

238 Our study greatly expands the compendium of insulin promoter regul

239 o nonlinear summation of synaptic inputs and greatly expands the computing power of a neural network.

240 LUCS greatly expands the designable structure space and offer

241 l layer of complexity to the p53 network and greatly expands the diversity of genomic elements direct

242 This structure, termed a "dendron," greatly expands the dynamic control of GnRH secretion in

243 Taken together, this study greatly expands the existing knowledge of the targets of

244 Warming by 4 degrees C greatly expands the extent, frequency, and intensity of

245 We conclude that the sumoylation cycle greatly expands the functional capacity of transcription

246 es are expressed as multiple isoforms, which greatly expands the functional repertoire of the encoded

247 -aptamers-in-droplets (RAPID), a method that greatly expands the generality of ultrahigh-throughput m

248 This discovery greatly expands the genetically encoded noncanonical ami

249 This study greatly expands the genomic representation of the tree o

250 The fifth major release greatly expands the heart of JASPAR-the JASPAR CORE subc

251 threshold optimization and network inference greatly expands the high-confidence TF network map in bo

252 n the renal cortex and the renal medulla and greatly expands the known differential proteome profiles

253 Our eY1H-derived network greatly expands the known repertoire of TF-cytokine gene

254 nt a new version of the CSA (CSA 2.0), which greatly expands the number of both curated (968) and aut

255 spectral image acquisition and analysis that greatly expands the number of fluorescent signatures dis

256 This work greatly expands the number of genes in each of these cat

257 This study greatly expands the number of genetic variants that may

258 The identification of four novel filaments greatly expands the number of known intracellular filame

259 pread modification of key metabolic pathways greatly expands the number of known substrates and sites

260 s the 2,5-diaminoimidazole motif, our method greatly expands the number of reported diaminoimidazoles

261 This method greatly expands the parameter space for engineering devi

262 ed from angiosperms to interactomic research greatly expands the possibility of conducting comparativ

263 We propose that this technology greatly expands the possible clinical applications of (2

264 High-throughput RNA sequencing (RNA-seq) greatly expands the potential for genomics discoveries,

265 Successful development of this transmitter greatly expands the potential for long-term studies of t

266 d its ability to yield protic functionality, greatly expands the potential of NHC-functionalized nobl

267 ate addition protocol to be developed, which greatly expands the range of products that can be made b

268 PADRE greatly expands the range of relationships that can be e

269 ERSA greatly expands the range of relationships that can be e

270 Alternative RNA splicing greatly expands the repertoire of proteins encoded by ge

271 This efficient approach greatly expands the repertoire of RNA editing targets an

272 This strategy greatly expands the scope of accessible DNA nanostructur

273 The CL intein thus greatly expands the scope of applications for protein tr

274 ed confocal micro-extensometer (ACME), which greatly expands the scope of existing methods for measur

275 This approach greatly expands the scope of KATs, KAT complexes, and Co

276 This greatly expands the scope of possible structures that ca

277 enolates, instead of alkali metal enolates, greatly expands the scope of the arylation of esters.

278 Such an increase greatly expands the scope of the technique, while provid

279 This strategy thus greatly expands the spatiotemporal length scales of live

280 The exchange method greatly expands the structural and functional variety of

281 This technique greatly expands the synthesis capabilities of flow litho

282 guide RNA (gRNA) required for targeting that greatly expands the targetable genome.

283 This relationship greatly expands the transcriptional master network regul

284 ics (including chemosensitivity testing) and greatly expands the value of biobanking.

285 dendrites of cortical pyramidal neurons and greatly expand their ability to integrate synaptic input

286 conventional industrial yeast strains could greatly expand their biotechnological utility.

287 st that neutrophils, provoked by mycoplasma, greatly expand their capacity to synthesize histamine, t

288 ACS to pure populations has the potential to greatly expand their future therapeutic application to t

289 ationally strained trans-cyclooctenes should greatly expand their usefulness especially when paired w

290 nanomaterials, such as gold nanorods, would greatly expand their utility as surface ligands.

291 s left this environment for the savannah and greatly expanded their dietary repertoire.

292 new generation of stem cell-based therapies, greatly expanding their therapeutic utility.

293 Here, we greatly expand this network through an RNAi-screen of 55

294 e-in signalling, which requires Galpha13 and greatly expands thrombi.

295 ion pattern observed in animals, albeit on a greatly expanded time scale.

296 This greatly expanded time-scale range enables the characteri

297 formed the most robustly in benchmarking and greatly expands upon the availability of interactions cu

298 Unexpectedly, the transgenic mesenchyme was greatly expanded with increased proliferation.

299 n region has been used for millennia and has greatly expanded with industrialization.

300 picorna-like viruses/Marnaviridae' clade was greatly expanded, with more than 800 added viruses.