ライフサイエンスコーパス: growth hormone secretagogue

1 percent identical to the human receptor for growth hormone secretagogues.

2 The ghrelin receptor growth hormone secretagogue 1 receptor (GHSR) is present

3 g periods and acts through its receptor, the growth hormone secretagogue 1a (GHSR1a), to promote food

4 Some growth hormone secretagogues act as agonists at the ghre

5 The recently discovered growth hormone secretagogue, ghrelin, is a potent agonis

6 ormone ghrelin, an endogenous ligand for the growth hormone secretagogue (GHS) receptor, yielded the

7 a potent, orally active agonist of the human growth hormone secretagogue (GHS) receptor.

8 The expression of ghrelin mRNAs and growth hormone secretagogue (GHS) receptors could be det

9 tic 2 (BMS-317180) was discovered as a human growth hormone secretagogue (GHS).

10 Growth hormone secretagogues (GHS) are a group of synthe

11 Small synthetic molecules termed growth hormone secretagogues (GHSs) act on the pituitary

12 ed here to obtain novel chemical entities as growth hormone secretagogues (GHSs), a small database of

13 ve insulin therapy and the administration of growth hormone secretagogues, have been encouraging.

14 ained another unapproved drug, including the growth hormone secretagogue ibutamoren, the peroxisome p

15 ), a potent, orally bioavailable benzolactam growth hormone secretagogue, is obtained from zwitterion

16 The truncated non-signaling ghrelin receptor growth hormone secretagogue R1b (GHS-R1b) has been sugge

17 f potent, selective, and orally bioavailable growth hormone secretagogue receptor (GHS-R) antagonists

18 and orally bioavailable tetralin carboxamide growth hormone secretagogue receptor (GHS-R) antagonists

19 The recent cloning of a growth hormone secretagogue receptor (GHS-R) from human

20 ormone expression, ghrelin and its receptor (growth hormone secretagogue receptor (GHS-R)) are widely

21 Ghrelin's effect is mediated by its receptor Growth Hormone Secretagogue Receptor (GHS-R), but the ph

22 f stimulation of the peptide's receptor, the growth hormone secretagogue receptor (GHS-R), in the cau

23 recently described endogenous ligand for the growth hormone secretagogue receptor (GHS-R), is produce

24 ide ghrelin is an endogeneous ligand for the growth hormone secretagogue receptor (GHS-R).

25 enic hormone, is an endogenous ligand of the growth hormone secretagogue receptor (GHS-R).

26 lin is the endogenous ligand for the type 1a growth hormone secretagogue receptor (GHS-R1a) and the o

27 y format designed for the early detection of growth hormone secretagogue receptor (GHS-R1a) antagonis

28 Ghrelin receptor, also known as growth hormone secretagogue receptor (GHS-R1a), is coexp

29 lates hunger signals in the hypothalamus via growth hormone secretagogue receptor (GHS-R1a).

30 The growth hormone secretagogue receptor (GHSR) (ghrelin rec

31 Growth hormone secretagogue receptor (GHSR) 1a is the on

32 genous antagonist and inverse agonist of the growth hormone secretagogue receptor (GHSR) has revived

33 The ghrelin receptor or growth hormone secretagogue receptor (GHSR) is a G-prote

34 Growth hormone secretagogue receptor (GHSR) is a recepto

35 how local hydration of the ghrelin receptor growth hormone secretagogue receptor (GHSR) is rearrange

36 rsistently increased ghrelin levels, whereas growth hormone secretagogue receptor (Ghsr) null mice sh

37 Synthetic agonists of the growth hormone secretagogue receptor (GHSR) rejuvenate t

38 rdiomyocytes and acts through the myocardial growth hormone secretagogue receptor (GHSR) to promote c

39 demonstrate that Ghrl and ghrelin receptor (growth hormone secretagogue receptor (GHSR)) are express

40 rived peptide ghrelin, and its receptor, the growth hormone secretagogue receptor (GHSR), both of whi

41 ells produce ghrelin and delta-cells express growth hormone secretagogue receptor (GHSR), suggesting

42 ding to the only known ghrelin receptor, the growth hormone secretagogue receptor (GHSR).

43 iency via interaction with its receptor, the growth hormone secretagogue receptor (GHSR).

44 Ghrelin enhances feeding by activating the growth hormone secretagogue receptor (GHSR).

45 Endogenous ghrelin receptors [growth hormone secretagogue receptor (GHSR)] are also pr

46 Ghrelin is the endogenous ligand for the growth hormone secretagogue receptor (GHSR; ghrelin rece

47 actions of ghrelin are mediated through the growth hormone secretagogue receptor 1a (ghrelin recepto

48 de-6 (GHRP-6) exhibits dual affinity for the growth hormone secretagogue receptor 1a (GHS-R1a) and th

49 The ghrelin receptor, also known as the growth hormone secretagogue receptor 1a (GHS-R1a), is a

50 by the stomach and acts at its receptor, the growth hormone secretagogue receptor 1a (GHSR1a), in the

51 siological functions of the ghrelin receptor growth hormone secretagogue receptor 1a (GHSR1a), includ

52 e, ghrelin, is a potent agonist at the human growth hormone secretagogue receptor 1a (hGHSR1a).

53 n-KO mice and C57BL/6N mice administered the growth hormone secretagogue receptor agonist HM01 or veh

54 ted form of ghrelin acts as a ligand for the growth hormone secretagogue receptor and can stimulate t

55 A novel neuronal growth hormone secretagogue receptor circuit involving u

56 in these pathological states and because the growth hormone secretagogue receptor has been identified

57 omach, ghrelin is the natural ligand for the growth hormone secretagogue receptor in the pituitary gl

58 modeling, we demonstrate that binding to the growth hormone secretagogue receptor is accompanied by a

59 ility by activating KATP conductance via the growth hormone secretagogue receptor subtype 1a-Galphai

60 Ghrelin, the natural ligand of the growth hormone secretagogue receptor type 1a (GHS-R1a),

61 tion of a postsynaptic ghrelin receptor, the growth hormone secretagogue receptor type 1a (GHS-R1a),

62 yl-ghrelin, which binds to and activates the growth hormone secretagogue receptor type 1a (GHS-R1a),

63 tide ghrelin is an endogenous ligand for the growth hormone secretagogue receptor type 1a (GHSR1a).

64 The growth hormone secretagogue receptor, GHSR1a, mediates t

65 ptide ghrelin, the endogenous ligand for the growth hormone secretagogue receptor, has been implicate

66 As a natural endogenous ligand of the growth hormone secretagogue receptor, it potently stimul

67 ated peptide acting by the activation of the growth hormone secretagogue receptor, namely, GHS-R1a.

68 e peptide's active blood-brain transport and growth hormone secretagogue receptor-1 agonist activity.

69 SignificanceThe modulation of growth hormone secretagogue receptor-1a (GHSR(1a)) signa

70 n(-)Sca1(+)cKit(+) cells, while ghrelin- and growth hormone secretagogue receptor-deficient (GHS-R-de

71 anterior pituitary cells express significant growth hormone secretagogue receptor.

72 is assumed to increase feeding by binding at growth hormone secretagogue receptors (GHS-R), the only

73 Ghrelin, produced in the stomach, acts on growth hormone secretagogue receptors (GHSRs) in hypotha

74 Growth hormone secretagogue receptors (GHSRs) in the cen

75 ghrelin require interaction with endothelial growth hormone secretagogue receptors.

76 receptor that is structurally related to the growth hormone secretagogue receptors.

77 ly by the expression of the ghrelin receptor growth hormone secretagogue type 1a (GHS-R1a) in the hyp