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1 orm a dimeric quadruplex structure with four guanine-quartets.
2 reted in terms of a repeating unit with four guanine-quartets and two stacked/intercalated ligand mol
6 ected mutagenesis implicate the formation of guanine quartets as critical components of the active st
10 on (UTR) sequences such as the 12-nucleotide guanine quartet (CGG)4 motif that can form RNA G-quadrup
12 ular quadruplex consisting of a stack of two guanine quartets connected by two external loops and one
13 osine residues and Hoogsteen hydrogen bonded guanine quartets, consistent with the quadruplex fold de
16 r pilin antigenic variation (Av) to occur, a guanine quartet (G4) structure must form upstream of pil
17 plex structures that result from stacking of guanine quartets in nucleic acids possess such thermodyn
19 2DIR data and DFT calculations suggests that guanine-quartets may already be present before the addit
20 ly folded structure dominated by two stacked guanine quartet motifs that are connected by three loops
21 the NMR evidence points toward K+-stabilized guanine quartets of slightly larger diameter relative to
25 ypically seen in folded structures formed by guanine quartets, such as the K(+) form of the thrombin
26 A structure consisting of a stacked array of guanine-quartets that can disrupt critical cellular func