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1 ic factors were shown to be activated by Ran guanosine triphosphatase.
2 ntestinal epithelia and are regulated by Rho guanosine triphosphatase.
3 where aPKC is activated by Rho family small guanosine triphosphatases.
4 that it requires activity of one or more Rho guanosine triphosphatases.
5 keletal changes induced by the Rho family of guanosine triphosphatases.
6 pparatus and physically interacts with small guanosine triphosphatases.
7 we show that the Insert B domain of the Dnm1 guanosine triphosphatase (a DRP) contains a novel motif
9 d to and phosphorylated spine-associated Rap guanosine triphosphatase activating protein (SPAR), a po
10 and dispersed at the lagging pole where the guanosine triphosphatase activating protein MglB disrupt
11 ere evidence that neurofibromin, via its Ras guanosine triphosphatase -activating activity, controls
12 the MKlp1-CYK4 centralspindlin complex is a guanosine triphosphatase-activating protein (GAP) for Ra
16 me 2q31 that encodes alpha2-chimaerin, a Rac guanosine triphosphatase-activating protein (RacGAP) sig
17 and Plk3 interact with spine-associated Rap guanosine triphosphatase-activating protein (SPAR), a re
18 pecifically binds to the IQ motif-containing guanosine triphosphatase-activating protein 1 (IQGAP1) s
20 ucleotide-exchange factor ECT-2, and the Rho guanosine triphosphatase-activating protein CYK-4 modula
23 ng the genes small ARF GAP1 (SMAP1), an ARF6 guanosine triphosphatase-activating protein that functio
26 human Tre-2/Bub2/Cdc16 domain-containing Rab guanosine triphosphatase-activating proteins (GAPs) and
29 downstream signaling to engage small GTPase (guanosine triphosphatase) activation and AMPAR synaptic
30 ion that is altered by inhibition of dynamin guanosine triphosphatase activity and is temporally dist
33 ling (RGS) proteins accelerate the intrinsic guanosine triphosphatase activity of heterotrimeric G-pr
34 ulin and it inhibited the colchicine-induced guanosine triphosphatase activity of tubulin, indicating
35 ing of the mutant ftsZ84, which has 1/10 the guanosine triphosphatase activity of wild-type FtsZ in v
36 merization, suppression of PDGF-induced Rac1 guanosine triphosphatase activity, and Akt and extracell
38 e kidney (MDCK) cells and identified the rho-guanosine triphosphatase adaptor and scaffolding protein
40 e proteins, inhibition of filamentous septin guanosine triphosphatases alleviates constriction defect
41 many membrane proteins, including the Ypt7p guanosine triphosphatase and a "SNARE complex" with Vam3
44 s the only known exchange factor for the Ran guanosine triphosphatase and performs essential roles in
45 t it was soluble and stable, did not bind to guanosine triphosphatases and bound more tightly to the
46 ormation requires the function of Rho family guanosine triphosphatases and reorganization of the acti
47 nse proteins, including interferon-inducible guanosine triphosphatases and the antimicrobial cathelic
48 ell adhesion molecules that activate RAS/RHO guanosine triphosphatases and their effector mitogen-act
49 importance and activates mTORC1 via the Rag guanosine triphosphatases and their regulators GATOR1 an
50 echanistically distinct enzymes (a kinase, a guanosine triphosphatase, and a ubiquitin protein hydrol
51 gulate protein levels of MIG-2, a Rho family guanosine triphosphatase, and/or down-regulate INA-1, an
52 d into motility signaling proteins (kinases, guanosine triphosphatases, and guanine exchange factors)
53 ons in members of the RAS subfamily of small guanosine triphosphatases are found in > 30% of all huma
56 is issue, Rafiq et al. reveal that the small guanosine triphosphatase ARF1, a well-known orchestrator
57 phosphatase-activating protein for the small guanosine triphosphatase Arf1, and gcs1 mutants displaye
58 d Kinesin-6 (which carries activators of Rho guanosine triphosphatase) at the cell cortex using total
62 gine off switch by sensing mitochondrial Rho guanosine triphosphatase-Ca(2+) and as a brake by anchor
65 e cortical PAR proteins (including the small guanosine triphosphatase CDC-42) have an active role in
67 report a positive feedback loop between the guanosine triphosphatase Cdc42, a central determinant in
69 ves localization of the conserved Rho-family guanosine triphosphatase, Cdc42, to the cortical region
73 a heterodimer composed of a conserved 54-kDa guanosine triphosphatase (cpSRP54) and a unique 43-kDa s
74 aintain a basal state of activation of small guanosine triphosphatases critical for normal T cell mot
75 uitment to the TASCC was amino acid- and Rag guanosine triphosphatase-dependent, and disruption of mT
76 uitment and assembly of some dynamin-related guanosine triphosphatases depends on adaptor proteins re
77 ino acid positions (p.G488R, p.A495V) in the guanosine triphosphatase domain, each segregating with a
78 pression of a dominant-active Drosophila Rho guanosine triphosphatase, Drac1, rescued photoreceptor m
80 is paper, we provide evidence that the large guanosine triphosphatase dynamin2 and its partner, endot
81 ociation factor Tif6 by the translocase-like guanosine triphosphatase Efl1 is a critical late maturat
83 es bound to tRNAs, nascent polypeptides, the guanosine triphosphatase elongation factors mtEF-Tu and
84 sion cycle 42 (Cdc42) is a member of the Rho guanosine triphosphatase family and has pivotal function
85 mber of a newly emerging 47-kilodalton (p47) guanosine triphosphatase family, LRG-47, that acts indep
86 s well as adherens junction proteins and Rho guanosine triphosphatase from the cell periphery to the
87 eractions of the ancient outer transmembrane guanosine triphosphatase, Fzo1, were required to promote
88 de exchange factor (GEF) for Tem1, the small guanosine triphosphatase governing activity of the Sacch
91 in complex 1 (mTORC1) protein kinase via its guanosine triphosphatase (GTPase) activating protein (GA
92 des Rop (RHO-like small G protein of plants) guanosine triphosphatase (GTPase) activating protein 4 (
93 ors (GEFs) and by RGS proteins, which act as guanosine triphosphatase (GTPase) activating proteins (G
95 action of SRP and SR, which stimulates their guanosine triphosphatase (GTPase) activities, leading to
96 s reveal the critical link between intrinsic guanosine triphosphatase (GTPase) activity and downstrea
97 ide-binding proteins (G proteins) that lacks guanosine triphosphatase (GTPase) activity in NIH-3T3 ce
98 eins are constitutively active because their guanosine triphosphatase (GTPase) activity is disabled.
101 ich repeat kinase 2 (LRRK2) protein has both guanosine triphosphatase (GTPase) and kinase activities,
104 erestingly, ciliary trafficking of the small guanosine triphosphatase (GTPase) Arl13b, loss of which
106 with Bnip-2, a protein that binds the small guanosine triphosphatase (GTPase) Cdc42 and a negative r
110 During mitochondrial division, the mechano-guanosine triphosphatase (GTPase) dynamin-related protei
112 mal subunit rotation and is catalyzed by the guanosine triphosphatase (GTPase) elongation factor G (E
115 in RAB23, which encodes a member of the RAB guanosine triphosphatase (GTPase) family of vesicle tran
116 and constitutively active member of the Rho guanosine triphosphatase (GTPase) family, has been impli
118 of mTORC1 by amino acids is mediated by Rag guanosine triphosphatase (GTPase) heterodimers on the ly
119 w that TIP47 also bound directly to the Rab9 guanosine triphosphatase (GTPase) in its active, GTP-bou
120 ecause activation of Rap1, an abundant small guanosine triphosphatase (GTPase) in platelets, contribu
121 uring cotranslational protein targeting, two guanosine triphosphatase (GTPase) in the signal recognit
122 Here, we investigated whether Rap1, a small guanosine triphosphatase (GTPase) known to promote integ
123 s targeting KRAS(G12C), a mutant form of the guanosine triphosphatase (GTPase) KRAS, are a promising
125 ornavirus infection was a large set encoding guanosine triphosphatase (GTPase) of immunity-associated
132 hibits eotaxin-induced activation of the Rho-guanosine triphosphatase (GTPase) Rac, and Rac2-deficien
133 ration and cell migration, whereas the small guanosine triphosphatase (GTPase) Rac1 mediates cell mig
134 abrogated PDGF-mediated activation of small guanosine triphosphatase (GTPase) Rac1, a member of the
136 ayed but not early ERK activation, the small guanosine triphosphatase (GTPase) Rap1 was considered as
138 activation bioprobe), we revealed that Cdc42 guanosine triphosphatase (GTPase) remains inactive withi
139 on of an activated form of Cdc42, a Rho-type guanosine triphosphatase (GTPase) required for cell pola
140 lular factors to activation of the monomeric guanosine triphosphatase (GTPase) Rho control cytoskelet
141 In yeast and animal cytokinesis, the small guanosine triphosphatase (GTPase) Rho1/RhoA has an estab
143 ly of heterotrimeric G proteins to the small guanosine triphosphatase (GTPase) RhoA, enabling Galpha(
145 y as part of a 43-member IFN-gamma-inducible guanosine triphosphatase (GTPase) superfamily in mouse a
147 e we show that transcripts for RhoA, a small guanosine triphosphatase (GTPase) that regulates the act
149 kinase G (PKG), protein kinase A (PKA), Rho guanosine triphosphatase (GTPase), and MLC phosphatase w
150 ein synthesis, elongation factor G (EF-G), a guanosine triphosphatase (GTPase), binds to the ribosoma
151 ivity is regulated by Rheb, a Ras-like small guanosine triphosphatase (GTPase), in response to growth
153 udy was to investigate the role of the small guanosine triphosphatase (GTPase), Rho, in the corneal e
154 osphorylation, we identified the RAB35 small guanosine triphosphatase (GTPase)-a protein previously i
156 sequence(s) of regulation of Ras activity by guanosine triphosphatase (GTPase)-activating proteins (G
157 re its Raptor subunit interacts with the Rag guanosine triphosphatase (GTPase)-Ragulator complex.
158 ic cells involves membrane-localized and Rac guanosine triphosphatase (GTPase)-regulated reduced nico
161 te plasma membrane-associated ROPs [Rho-like guanosine triphosphatases (GTPase) from plants], leading
162 chromosome [SRPX], and retinitis pigmentosa guanosine triphosphatase [GTPase] regulator [RPGR]) are
163 ownstream target of Rho (a Ras-related small guanosine triphosphatase [GTPase]), is associated with l
164 idues in switch region I of immunity-related guanosine triphosphatases (GTPases) (IRGs), a family of
166 C1 is activated on lysosomes by Rag and Rheb guanosine triphosphatases (GTPases) and drives biosynthe
167 nucleotide exchange factors specific for Rho guanosine triphosphatases (GTPases) and invariably posse
168 ide exchange factors (GEFs) specific for Rho guanosine triphosphatases (GTPases) and invariably posse
169 membrane protein that interacts with the Rag guanosine triphosphatases (GTPases) and Ragulator in an
170 (mTORC1) is recruited to the lysosome by Rag guanosine triphosphatases (GTPases) and regulates anabol
171 phatidylinositol 4-kinases (PI4Ks) and small guanosine triphosphatases (GTPases) are essential for pr
176 yclical activation and inactivation of small guanosine triphosphatases (GTPases) by their specific gu
177 ns, this process is mediated by dynamin-like guanosine triphosphatases (GTPases) called atlastins (AT
183 creasing the activity of the recycling small guanosine triphosphatases (GTPases) Rab4 or Rab11 was su
187 al cells, signaling pathways involving small guanosine triphosphatases (GTPases) regulate cell polari
189 st cells, signaling pathways involving small guanosine triphosphatases (GTPases) regulate polarized o
191 r-bundle morphogenesis whereby different Rho guanosine triphosphatases (GTPases) regulate the initiat
193 histicated mechanisms to modulate Rho family guanosine triphosphatases (GTPases) to mediate specific
194 uding amino acids, which act through the Rag guanosine triphosphatases (GTPases) to promote mTORC1 tr
197 e an interferon (IFN)-inducible subfamily of guanosine triphosphatases (GTPases) with well-establishe
198 involving the Ragulator complex and the Rag guanosine triphosphatases (GTPases), causing release of
200 e group of proteins, the Rho family of small guanosine triphosphatases (GTPases), is critical for thi
201 ce of RIT1 to other members of the Ras small guanosine triphosphatases (GTPases), mutations affecting
203 ner thought to be dependent on the Rag small guanosine triphosphatases (GTPases), the Ragulator compl
204 These processes all involve Rho family small guanosine triphosphatases (GTPases), which are regulated
206 y the activation of Ras homolog (Rho) family guanosine triphosphatases (GTPases), which regulate the
207 Rag proteins--a family of four related small guanosine triphosphatases (GTPases)--interact with mTORC
214 ular, we focus on the role of the Rho family guanosine triphosphatases in endothelial function and va
216 nin regulates the activity of the Rho family guanosine triphosphatases (including RhoA and Rac1) in a
217 We found that the murine Irgm1 (LRG-47) guanosine triphosphatase induced autophagy and generated
218 le protein 42 (Cdc42Hs) is a small, Rho-type guanosine triphosphatase involved in multiple cellular p
222 a genetically encoded, photoactivatable Rac guanosine triphosphatase is sufficient to direct migrati
224 ere, we show that dynamin1 (Dyn1), the large guanosine triphosphatase, is an interacting partner of I
232 e show that the mitochondrial outer membrane guanosine triphosphatase mitofusin (Mfn) 2 mediates Park
235 Proteolytic cleavage of the dynamin-like guanosine triphosphatase OPA1 in mitochondria is emergin
238 IC4 and RIC3 pathways downstream of the ROP1 guanosine triphosphatase promoting actin assembly and di
245 ine nucleotide exchange factor for the small guanosine triphosphatase Rab8, to promote recruitment of
247 toward PDGF and also activation of the small guanosine triphosphatase Rac, which is essential for pro
249 es (Paks), downstream effectors of the small guanosine triphosphatases Rac and Cdc42, biochemically c
252 high degree of sequence similarity, the Rho guanosine triphosphatases Rac1 and Rac2 regulate distinc
254 nal display analysis, to show that the small guanosine triphosphatase Rac2 is expressed selectively i
255 ly was mediated by chromosomes and the small guanosine triphosphatase Ran in a process requiring ~16
258 were assembled around beads coated with the guanosine triphosphatase Ran, forming pseudo-nuclei that
261 diated activation of the integrin regulatory guanosine triphosphatase Rap1 via the recruitment and ac
263 uncaging to image the activity of the small guanosine triphosphatase Ras after NMDA receptor activat
264 mTOR is directly activated by the small guanosine triphosphatase Ras homolog enriched in brain (
265 l adhesion reduction by activating the small guanosine triphosphatase Ras homolog family member J by
267 inhibition of p75NTR signaling to the small guanosine triphosphatase Rho resulted in impaired HSC di
268 uanine exchange factor for the Rho family of guanosine triphosphatases (Rho GEF GTPases), as a protei
269 , and CTNNB1 (encoding beta-catenin) and RHO guanosine triphosphatase [RHO GTPase, RHO], two signalin
271 rotein kinase c-Src and stimulated the small guanosine triphosphatase RhoA, consequently inhibiting c
273 on factor FoxF directly upregulate the small guanosine triphosphatase RhoDF, which synergizes with Cd
275 show that mouse embryos that lack the small guanosine triphosphatase RSG1 die at embryonic day 12.5,
277 d by pleiotropic perturbations to Rho family guanosine triphosphatase signaling and myosin II activit
280 -membrane receptor for DRP1, the cytoplasmic guanosine triphosphatase that catalyzes mitochondrial fi
281 duced activation of Rap1A, a phox-associated guanosine triphosphatase that is regulated by cAMP.
283 ynamin-related protein 1 (Drp1), a cytosolic guanosine triphosphatase that polymerizes and constricts
284 protein kinases and the regulation of small guanosine triphosphatases that control cellular movement
285 s based on the activity of Rho and Rap small guanosine triphosphatases that control integrin activati
286 2 (SEPT2), a member of the septin family of guanosine triphosphatases that form a diffusion barrier
296 ture-sensitive allele of the shibire dynamin guanosine triphosphatase, which is required for synaptic
297 in the appressorium by means of four septin guanosine triphosphatases, which polymerize into a dynam
299 tioning at this same step, including the Rab guanosine triphosphatase Ypt1p, which associated with cy
300 like other organelles, requires a Rab-family guanosine triphosphatase (Ypt7p), a Rab effector and Sec