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1 hrough MyoII assembly via regulation of Rap1-guanosine triphosphate.
2 guanosine diphosphate-bound complex to eIF2-guanosine triphosphate.
3 ubunit to exchange guanosine diphosphate for guanosine triphosphate.
4 tated by binding to guanosine diphosphate or guanosine triphosphate.
5 osine monophosphate (AMP) in the presence of guanosine triphosphate.
6 eled, biotinylated, or cross-linker-modified guanosine triphosphates.
7 uanosine triphosphate (8-oxo-dGTP) and 8-oxo-guanosine triphosphate (8-oxo-GTP) from the nucleotide p
9 gnaling by converting active Ras is bound to guanosine triphosphate, activating Ras into inactive Ras
10 ll polarity in the context of elevated Cdc42-guanosine triphosphate activity, similar to nonmalignant
12 P, and ribo-GTP as well as the thymidine and guanosine triphosphate analogs ddTTP, ddGTP, and dITP.
13 the corneas were permeabilized to introduce guanosine triphosphate analogs into the corneal epitheli
14 an electrode containing the non-hydrolysable guanosine triphosphate analogue, guanosine 5'-thio-triph
15 App, and an associated depletion of cellular guanosine triphosphate and adenosine triphosphate pools,
16 30) catalyzes the reversible condensation of guanosine triphosphate and beta-l-fucose-1-phosphate to
17 the nucleotide-sugar GDP-beta-l-fucose from guanosine triphosphate and beta-l-fucose-1-phosphate.
18 G in a conformation intermediate between the guanosine triphosphate and guanosine diphosphate forms.
20 e VPS15 pseudokinase domain binds tightly to guanosine triphosphate and stabilizes a web of interacti
21 entry site RNA, elongation factor eEF2, GTP (guanosine triphosphate), and sordarin, hygromycin B pref
22 s reaction, but also adenosine triphosphate, guanosine triphosphate, and cytidine triphosphate were s
25 = 0.0027], and mutations located within the guanosine triphosphate-ase region (odds ratio = 2.29, 95
26 utative Rap1 effector, colocalizes with Rap1-guanosine triphosphate at the leading edge and is requir
27 initiating NTP concentrations [adenosine or guanosine triphosphate (ATP or GTP), depending on the rr
28 (Gsalpha) of the stimulatory heterotrimeric guanosine triphosphate binding protein (G protein) Gs ac
29 The Vam2/6p complex then binds to Ypt7p, a guanosine triphosphate binding protein of the Rab family
30 ng or mutation of the SR-[Formula: see text] guanosine triphosphate binding site cause an N-glycosyla
33 utively activated stimulatory heterotrimeric guanosine triphosphate-binding protein alpha subunit (Ga
34 Mammalian nucleostemin (NS) is a nucleolar guanosine triphosphate-binding protein implicated in cel
35 ated protein kinases ERK-1 and ERK-2 and the guanosine triphosphate-binding protein p21ras were found
37 n activated nucleotide exchange on the small guanosine triphosphate-binding protein RhoA in seconds.
41 predicted a protein with homology to several guanosine triphosphate-binding protein-coupled seven-tra
42 nd appeared to be mediated by heterotrimeric guanosine triphosphate-binding proteins (G proteins).
43 to identify alpha-subunits of heterotrimeric guanosine triphosphate-binding proteins in lens cell pop
47 f at least four large families of regulatory guanosine triphosphate-binding proteins, including the A
48 septins, a conserved family of polymerizing guanosine triphosphate-binding proteins, localized to th
49 ion have been characterized, including small guanosine triphosphate-binding proteins, soluble N-ethyl
51 a,l]P-induced hyperplasia, but the levels of guanosine triphosphate-bound (active) H-ras protein and
52 wnstream of Ras and cycle between the active guanosine triphosphate-bound and inactive guanosine diph
55 that EVI5 preferentially interacts with the guanosine triphosphate-bound form of Rab11, and in a GAP
56 process that depended on the presence of the guanosine triphosphate-bound form of the small guanosine
57 ed spatially and MglA only binds MreB in the guanosine triphosphate-bound form, the motility complexe
59 y been defined as an interaction surface for guanosine triphosphate-bound Ras, single amino acid subs
60 l-length Trio, led to increased abundance of guanosine triphosphate-bound RhoA (RhoA.GTP) in human ce
62 uanosine monophosphate (cGMP) synthesis from guanosine triphosphate by RetGC1 in the presence of E6S/
63 -binding family of proteins that bind to the guanosine triphosphate cap at growing microtubule plus e
64 ap structures and found that an unmethylated guanosine triphosphate cap led to the lowest bias and hi
65 otein synthesis via assembly of the 7-methyl-guanosine triphosphate cap-dependent translation complex
66 properties, including the requirement for a guanosine triphosphate cofactor and the generation of lo
68 yed a significantly increased stimulation by guanosine triphosphate compared with the E23/S1369 haplo
70 ial cells (HBMECs) induces the expression of guanosine triphosphate cyclohydrolase (GCH1), the rate-l
75 nflammatory cell-dependent increase of iNOS, guanosine triphosphate cyclohydrolase I, tetrahydrobiopt
77 rahydrobiopterin (BH4) biosynthetic enzymes (guanosine triphosphate cyclohydrolase-1 and dihydrofolat
78 lease by either agonist, indicating that the guanosine triphosphate-dependent actions of VIP and carb
79 e-miRNAs directly and specifically, in a Ran guanosine triphosphate-dependent manner, but interacts o
80 ith and dissociate from donor membranes in a guanosine triphosphate-dependent manner, can also active
82 gest that CRFG may be involved in regulating guanosine triphosphate-dependent nuclear events that are
83 c proteins including a guanosine diphosphate/guanosine triphosphate exchange factor for Sar1p have be
85 te that Rab-activating guanosine diphosphate/guanosine triphosphate exchange factors (GEFs) display t
88 ver under both basal and agonist stimulated (guanosine triphosphate gamma S and forskolin) conditions
89 form of the Rho-associated protein (Rac) and guanosine triphosphate (GTP) (RacGTP) was immunolabeled
91 m extorquens MeaB bound to a nonhydrolyzable guanosine triphosphate (GTP) analog guanosine-5'-[(beta,
92 dels of the dynamin helical polymer bound to guanosine triphosphate (GTP) analogs define earlier stag
93 ger, cGAMP, is generated using intracellular guanosine triphosphate (GTP) and adenosine triphosphate
94 resence of 32P-alpha-adenosine triphosphate, guanosine triphosphate (GTP) and either carbachol or end
97 s have been hampered by the high affinity of guanosine triphosphate (GTP) and lack of allosteric regu
98 ps26/29/35 trimer specifically binds to Rab7-guanosine triphosphate (GTP) and localizes to Rab7-conta
99 ongation factor Tu (EF-Tu), which hydrolyzes guanosine triphosphate (GTP) and releases tRNA in respon
101 Dynamin superfamily molecular motors use guanosine triphosphate (GTP) as a source of energy for m
102 ted by cell-surface receptors, which promote guanosine triphosphate (GTP) binding and dissociation of
103 nd maturing phagosomes, whereas inactivating guanosine triphosphate (GTP) binding blocks the dissocia
104 show that the causative mutation lies in the guanosine triphosphate (GTP) binding pocket of alpha-1 t
105 own as 1,3-beta-glucan synthase), requires a guanosine triphosphate (GTP) binding protein for activit
106 f CXCR4 and Rac-1 in lipid rafts facilitated guanosine triphosphate (GTP) binding/activation of Rac-1
107 guanosine triphosphatase Ran is loaded with guanosine triphosphate (GTP) by the chromatin-bound guan
108 seconds) and extensive (30% to 40% of total) guanosine triphosphate (GTP) charging of endogenous plat
109 tic chromosomes were surrounded by steep Ran guanosine triphosphate (GTP) concentration gradients, in
111 of 6BH(4) de novo synthesis is controlled by guanosine triphosphate (GTP) cyclohydrolase I (GTPCHI) a
114 naling), appears to function by facilitating guanosine triphosphate (GTP) exchange on the heterotrime
115 ation factor G (EF-G) hydrolyzes energy-rich guanosine triphosphate (GTP) for every amino acid incorp
116 anism is critical for spatial control of Ran-guanosine triphosphate (GTP) gradients that guide mitoti
117 Direct contacts between the RNA and CRM1/Ran-guanosine triphosphate (GTP) highlight the critical role
119 opsin (R*) and inactivation of transducin by guanosine triphosphate (GTP) hydrolysis are the leading
122 -bound, state of the oncoprotein and require guanosine triphosphate (GTP) hydrolysis for inhibition.
125 ,(7) a site that changes conformation during guanosine triphosphate (GTP) hydrolysis.(8) Consequently
126 n signaling 9 (RGS9)-catalyzed hydrolysis of guanosine triphosphate (GTP) in G protein-phosphodiester
128 tyrosine kinase (RTK) ligands increase RhoA-guanosine triphosphate (GTP) in untransformed and transf
129 Addition of cytosol and the hydrolysis of guanosine triphosphate (GTP) induced caveolar fission.
133 from Cdc42 and elevates intracellular Cdc42-guanosine triphosphate (GTP) levels in cells with inacti
135 f rat hepatocytes with TDCA and TCA promoted guanosine triphosphate (GTP) loading of G(i1alpha), G(i2
137 s transiently transfected with empty vector, guanosine triphosphate (GTP) locked dominant active Rab4
138 es; beginning with the N(7) methylation of a guanosine triphosphate (GTP) molecule, followed by the c
139 ctly associates with the alpha-tubulin-bound guanosine triphosphate (GTP) molecule, impairing the int
140 n between Crm1 and Gcn4 requires neither Ran-guanosine triphosphate (GTP) nor the nuclear export sequ
141 les were attributed to the hydrolysis of the guanosine triphosphate (GTP) nucleotide bound to the bet
142 hosphorylation reduces intracellular GDP and guanosine triphosphate (GTP) pools and decreases mitogen
143 rtical motor complexes that depends on a Ran-guanosine triphosphate (GTP) signal [12], which is suffi
144 enase (IMPDH) is the rate-limiting enzyme in guanosine triphosphate (GTP) synthesis and assembles int
145 for guanosine diphosphate (GDP) relative to guanosine triphosphate (GTP) that is consistent with a 3
148 expected allosteric activation of SOS by Ras-guanosine triphosphate (GTP) was conspicuously absent in
149 ent in vitro-selected RNA aptamers that bind guanosine triphosphate (GTP) with K(d)s ranging from 8 m
151 s), such as adenosine triphosphate (ATP) and guanosine triphosphate (GTP), are signaling and bioenerg
152 ne diphosphate ribosylation factor 1 (Arf-1)-guanosine triphosphate (GTP), cargo sorting signals, and
153 d the availability of ATP, which regenerates guanosine triphosphate (GTP), powers ribosomes, and prom
154 heir reduced intrinsic rate of hydrolysis of guanosine triphosphate (GTP), which results in their acc
155 ctivation by adenosine triphosphate (ATP) or guanosine triphosphate (GTP), with ATP favoring the inco
157 olecules to the cleft between the N-terminal guanosine triphosphate (GTP)-binding and the C-terminal
158 and contains an adenosine triphosphate (ATP)/guanosine triphosphate (GTP)-binding motif that has homo
159 ning as a nucleotide exchange factor for the guanosine triphosphate (GTP)-binding protein Arf1p, is r
162 (MT) stabilization is regulated by the small guanosine triphosphate (GTP)-binding protein Rho and its
164 diverse receptor subtypes includes the small guanosine triphosphate (GTP)-binding protein, p21ras.
167 in-treated cells showed translocation of ras guanosine triphosphate (GTP)-binding proteins from membr
170 he authors demonstrate that TBSV co-opts the guanosine triphosphate (GTP)-bound active form of the en
173 diphosphate (GDP)-bound form (RanGDP) and a guanosine triphosphate (GTP)-bound form (RanGTP) and pla
174 ant proteins, we show that Ypt31/32 in their guanosine triphosphate (GTP)-bound form interact directl
175 C2[E62K] displayed characteristics of active guanosine triphosphate (GTP)-bound RAC2 including enhanc
177 n is initiated by the interaction of active, guanosine triphosphate (GTP)-bound Ras-related protein 1
178 0beta-Rab5 association maintains Rab5 in its guanosine triphosphate (GTP)-bound state and enhances th
182 es are ultimately due to FtsZ's capacity for guanosine triphosphate (GTP)-dependent, reversible polym
183 activated and deactivated for assembly by a guanosine triphosphate (GTP)-driven reaction cycle, and
184 atrunculin A primed platelets for Ca(2+)- or guanosine triphosphate (GTP)-gamma-S-induced alpha-granu
185 aused lethality and perturbed binding to Ran guanosine triphosphate (GTP)-importin-beta, accumulation
186 aT) resides within a domain that undergoes a guanosine triphosphate (GTP)-induced conformational chan
187 , of VASH1/SVBP is much greater on mimics of guanosine triphosphate (GTP)-MTs than on guanosine dipho
188 nding protein-related protein 1L (ORP1L) are guanosine triphosphate (GTP)-Rab7 effectors that instiga
195 dition, we demonstrated that OA induces Rho1 guanosine triphosphate (GTP)ase activation in the follic
196 GFP)-tagged dynamin, a large mechanochemical guanosine triphosphate (GTP)ase implicated in the libera
198 on of force by phenylephrine, endothelin and guanosine triphosphate (GTP)gammaS, but did not inhibit
199 a unique complex in which hydrolyses of both guanosine triphosphates (GTP) are activated in a shared
200 hen Anillin is knocked down, active Rho (Rho-guanosine triphosphate [GTP]), F-actin, and myosin II ar
201 plicated in chromatin-stimulated nucleation, guanosine triphosphate(GTP)-bound Ran and its effector,
202 r 1 (ARF1) is proposed to be involved in the guanosine triphosphate- (GTP-) dependent, reversible ass
203 The growth and shortening of microtubules in guanosine triphosphate-(GTP-) mediated dynamic instabili
207 tal organization and activity of Rho and Rac guanosine triphosphate hydrolase (GTPase) and Yes-associ
209 biologic functions partly through the small guanosine triphosphate hydrolase (GTPase) Rac1 (ras-rela
210 ired for TLR-induced activation of the small guanosine triphosphate hydrolase (GTPase) Rac1 (ras-rela
212 to the plasma membrane is regulated by small guanosine triphosphate hydrolases (GTPases) and is essen
213 sing number of assembly factors, among which guanosine triphosphate hydrolases (GTPases) are the most
214 ns associated with the Ras homolog family of guanosine triphosphate hydrolases (Rho GTPases), and cel
216 domain of PLC-beta3 subsequently accelerates guanosine triphosphate hydrolysis by Galpha(q), causing
217 ng of guanosine-5'-O-(3-thiotriphosphate) or guanosine triphosphate hydrolysis by the G protein.
218 egulates actin (dis-)assembly, and catalytic guanosine triphosphate hydrolysis is found in tubulin (d
221 utes and remained stable for hours, required guanosine triphosphate hydrolysis, and recruited four GB
223 ore insertion required the generation of Ran guanosine triphosphate in the nuclear and cytoplasmic co
224 MP) in vitro from adenosine triphosphate and guanosine triphosphate in the presence of DNA but not RN
226 we show that FtsY-SecY complex formation is guanosine triphosphate independent but requires a phosph
227 ion of the rate constant for dissociation of guanosine triphosphate indicated that at pH 7.5 the rele
228 ite inhibited eukaryotic initiation factor 2-guanosine triphosphate-initiator methionyl transfer RNA
229 A Rag mutant that is constitutively bound to guanosine triphosphate interacted strongly with mTORC1,
231 cells have suggested a critical role of Rap1-guanosine triphosphate-interacting adaptor molecule (RIA
232 te cyclase (sGC) catalyzes the conversion of guanosine triphosphate into cyclic guanosine-3',5'-monop
233 served large GTPases (enzymes that hydrolyze guanosine triphosphate) involved in endocytosis and vesi
234 olves a complex rearrangement in which C8 of guanosine triphosphate is inserted between C2' and C3' o
237 small guanosine triphosphatases, binding to guanosine triphosphate leads to interaction with downstr
238 convenient synthetic routes to the oxidized guanosine triphosphate lesions spiroiminodihydantoin-2'-
239 evels correlating with heightened basal Rac1-guanosine triphosphate levels and increased reactivity.
244 g, the enzyme exhibits strong preference for guanosine triphosphate over adenosine triphosphate as th
246 oteins normally using adenosine triphosphate/guanosine triphosphate, probably explains the disease.
247 BB, which are associated with CDC42, a small guanosine triphosphate protein linked to T-cell activati
248 m conversion of guanosine diphosphate-Rac to guanosine triphosphate-Rac following ITAM stimulation.
249 plasmic complex, an association regulated by guanosine triphosphate rac1 ([GTP]rac1) but not by [GTP]
250 s sustained by karyopherins (Kaps) and a Ran guanosine triphosphate (RanGTP) gradient that imports nu
251 d, and escort NLS-NCs through NPCs while Ran guanosine triphosphate (RanGTP) promotes their release f
254 n phosphoinositide-3 kinase (PI3K) and small guanosine triphosphate Ras signaling networks commonly d
257 nteract with effector proteins when bound to guanosine triphosphate, stimulating downstream signaling
259 t retain the intrinsic capacity to hydrolyze guanosine triphosphate, suggesting that the mechanism of
260 Resting and activated sGC enzyme converts guanosine triphosphate to an important second messenger
261 -A catalyzes the intracellular conversion of guanosine triphosphate to cGMP (cyclic 3',5'-guanosine m
263 the conformational change of EF-Tu from the guanosine triphosphate to guanine diphosphate conformati
264 by accelerating the hydrolysis of active Ras-guanosine triphosphate to inactive Ras-guanosine diphosp
266 ency of spontaneous rescue unless patches of guanosine triphosphate tubulin are artificially embedded
267 at microtubules elongate by addition of bent guanosine triphosphate tubulin to the tips of curving pr