ライフサイエンスコーパス: gut

1 henotype to the organoids and throughout the gut.

2 cteria, e.g. to the ones living in the human gut.

3 igen, and the parent protein in the hookworm gut.

4 zontal transfer from commensals in the human gut.

5 s-derived sugars as crucial nutrients in the gut.

6 mically-administered daptomycin reaching the gut.

7 zation, invasion, and dissemination from the gut.

8 ization and inflammatory activity within the gut.

9 equent oxidative stress, specifically in the gut.

10 dvantage against competitors in the inflamed gut.

11 n found to survive passage through waterbird guts.

12 during passage through the bile ducts to the gut(4).

13 ogeneous real-world environments such as the gut(6,7), solid tumours(8,9), bioreactors(10) or soil(11

14 Connections between the gut and brain monitor the intestinal tissue and its micr

15 ay contribute to latent HIV infection in the gut and may serve as new targets for therapies aimed at

16 h protein increases amino acid levels in the gut and promotes pathogen colonization.

17 e in stimulating calcium absorption from the gut and promoting skeletal health, as well as many other

18 chia coli promotes alphaSyn pathology in the gut and the brain.

19 also released by microbiota's enzymes in the gut and therefore an indicator for the proportion of fer

20 the butyrate-associated GLP-1 pathway in the gut, and oral supplementation with butyrate provides new

21 issue-resident MBC gene signature as well as gut- and spleen-specific signatures.

22 though siderophore-like BGCs from the infant gut are predominantly associated with Enterobacteriaceae

23 e bodies that are passively pushed along the gut as the matrix gets remodelled.

24 days (P = 0.003), driven by the presence of gut-associated bacteria (e.g., species of the Lachnospir

25 nes from single cells, we find that 5-10% of gut-associated germinal centres from specific-pathogen-f

26 The frequency of highly selected gut-associated germinal centres is markedly higher in ge

27 on of B cells can take place in steady-state gut-associated germinal centres, at a rate that is tunab

28 ere we describe a method for isolating human gut-associated lymphoid tissues (GALTs) that allows unpr

29 The hypothesized link between gut bacteria and autism spectrum disorder (ASD) has been

30 rocessed from indigestible dietary fibers by gut bacteria and have immunomodulatory properties.

31 We identified specific gut bacteria and their metabolic functions associated wi

32 Specifically, we suggest that individual gut bacteria are likely to diverge in patterns recapitul

33 nges to gut microbiota, such as depletion of gut bacteria that produce short-chain fatty acids (SCFAs

34 tern also promotes the growth of unhealthful gut bacteria, fostering, among other things, the product

35 lized countries are characterized by a lower gut bacterial diversity as well as by changes in composi

36 healthy individuals as well as diverse human gut bacterial isolates were capable of inactivating the

37 achieve quantitative and temporal control of gut bacterial metabolism in order to reveal its local an

38 and indole-3-aldehyde-which are derived from gut bacterial metabolism of the essential amino acid try

39 to the brain and discuss direct effects that gut bacterial molecules are likely exerting on specific

40 te immune activation promoted by products of gut bacterial overgrowth/dysbiosis and altered intestina

41 n, persistence, and inflammatory activity of gut bacterial populations.

42 In humans, dietary protein increases gut bacterial production of hydrogen sulfide (H(2)S), in

43 ed light on the diversity and composition of gut bacteriome and suggest consequences for human and an

44 a molybdenum-dependent enzyme from the human gut bacterium Eggerthella lenta that dehydroxylates cate

45 tive pathway for carnitine metabolism in the gut bacterium Eubacterium limosum Instead of forming TMA

46 ranscriptional mechanisms play a key role in gut barrier dysfunction.

47 t-chain fatty acids and bile acids, improved gut barrier integrity and increased intestinal T regulat

48 erging research demonstrates that microbiota-gut-brain (MGB) axis changes are associated with depress

49 the ecological relevance of this microbiome-gut-brain (MGB) axis outside the laboratory remains unex

50 e mechanism and the effect of PEA-OXA on the gut-brain axis in rats subjected to experimental colitis

51 m (spinal cord and brain) that underlies the gut-brain axis, is via spinal afferent neurons, with cel

52 al programming and/or through the microbiome-gut-brain axis.

53 ogenesis of schizophrenia via the microbiota-gut-brain axis.

54 Gut-brain connections may be mediated by an assortment o

55 ure refers to the conditions as disorders of gut-brain interaction.

56 sion of a specific bacterial gene within the gut by oral administration.

57 dietary metabolites/signals compose the rich gut chemical environment, which profoundly impacts virul

58 A better understanding of the gut-CNS axis will shed new light on the mechanisms of di

59 cell surfaces, and contributes to efficient gut colonization and host infection.

60 Co-evolution of gut commensal bacteria and humans has ensured that the m

61 proximately 5%) escape into the colon, where gut commensal bacteria convert them into various intesti

62 by Bacteroides thetaiotaomicron, a prominent gut commensal species.

63 Here, we identify mouse gut commensals that utilize mucus-derived monosaccharide

64 Such 'leaky gut' conditions result in systemic inflammation, of whic

65 Based on more than 2000 gut content analyses from animals ranging over three ord

66 elation with markers of disease progression, gut damage, bacterial translocation, and inflammation.

67 Their interactions with gut-derived bacterial lipopolysaccharide (LPS) are impli

68 ng more apparent that the connection between gut dysbiosis and age-related diseases may lie in how th

69 indicating that c-ART partially reversed the gut dysbiosis associated with SIV infection.

70 complex interrelationship may exist between gut dysbiosis, miRNA profiling and SCFA level in respons

71 al n-3 PUFA intake worsens MIA-induced early gut dysfunction, including modification of gut microbiot

72 that neonatal microbial colonization of the gut elicits concomitant effects on the host CNS, which p

73 gand of alpha(4)beta(7) that is expressed on gut endothelial cells.

74 ught to determine how it could influence the gut environment in ICP to alter enterohepatic signalling

75 the area between the peritrophic matrix and gut epithelium called the ectoperitrophic space.

76 9 infection on the gut microbiome and on the gut epithelium.

77 duce short-chain fatty acids (SCFAs) through gut fermentation of fiber, in CKD and diabetes.

78 olic compounds bioaccessibility after 4 h of gut fermentation.

79 ality from gastrointestinal syndrome, spared gut function and epithelial integrity, and spared cell d

80 These findings highlight the complex role a gut fungus can play in influencing the microbial communi

81 ut of intestinal neural circuits to maintain gut homeostasis and health.

82 t the effect of aldafermin, an analog of the gut hormone FGF19, versus placebo on the gut microbiota

83 In the gut, IgA contributes to the establishment of a mutualist

84 inus allergens in breast milk, which disrupt gut immune homeostasis and prevents oral tolerance induc

85 The allergy preventive effects of gut immune modulation by bacterial compounds are still n

86 Our results suggest that the microbiome-gut-immune axis can be modified by DEHP and emphasize th

87 erived from the gut microbiome affecting the gut-immune-brain axis and the molecular mechanisms invol

88 ence cancer immunotherapy through activating gut immunity.

89 ed DNA viruses that infects the cells of the gut in invertebrates, including insects and crustaceans.

90 In this pathway, benign sensations from the gut induce maladaptive cognitive or affective processes

91 the birth cohort, we measured biomarkers of gut inflammation (myeloperoxidase, neopterin), permeabil

92 However, the effect of gut inflammation on this axis is unknown despite reports

93 h gut microbial metabolism in the context of gut inflammation.

94 ila melanogaster, we identify a key role for gut-innervating neurons with sex- and reproductive state

95 rs, all of which are precursors for impaired gut integrity and performance.

96 The relationship between gut integrity, microbial translocation, and inflammation

97 relationship with the tomato psyllid at the gut interface.

98 consider, especially in HIV infection where gut-intestinal barrier dysfunction could facilitate T ce

99 s nerve in transforming sugar sensing by the gut into behavioral reinforcement via midbrain dopamine

100 The gut is home to the body's largest population of plasma c

101 lpha(4)beta(7)-expressing lymphocytes to the gut is mediated by MAdCAM, the natural ligand of alpha(4

102 The gut-joint axis of inflammation in SpA is further reinfor

103 sis and altered intestinal barrier function (gut-liver axis) and by episodes of sepsis to cause chole

104 t aim to modulate the gut microbiota and the gut-liver axis.

105 This study has identified a TFEB-mediated gut-liver signaling axis that regulates hepatic choleste

106 efenses in the form of hindgut expansion and gut melanization.

107 Here, we analyze gut metagenomic data from mother-infant pairs and patien

108 lated during functional screening of a human gut metagenomic library using Lactococcus lactis MG1363

109 of segmentous filamentous bacteria (SFB), a gut microbe residing on ileum villi and PP FAE that medi

110 s affecting the gut microbiota, the roles of gut microbes and their bioproducts in the development an

111 Gut microbes exhibit diurnal rhythmicity, and disruption

112 ival in primates is facilitated by commensal gut microbes that ferment otherwise indigestible plant m

113 toxifies lipopolysaccharide (LPS), regulates gut microbes, and dephosphorylates proinflammatory nucle

114 Some melanoidins were extensively used by gut microbes, increasing production of short chain fatty

115 f these changes were related to sleep and/or gut microbial alpha diversity.

116 , we track intestinal stem cell lineages and gut microbial colonization in single animals, revealing

117 ship between the composition and function of gut microbial communities and early-onset calcium oxalat

118 We sampled gut microbial communities from 55 moose in a population

119 infants did not affect the structure of the gut microbial communities until the children were aged 9

120 tem for sustained growth of subject-specific gut microbial communities, an ex vivo drug metabolism sc

121 eptococcus, and Bacteroides), and chimpanzee gut microbial communities, like those of humans, exhibit

122 tus, sexual risk category, and gender impact gut microbial community alpha-diversity.

123 The gut microbial community exhibited marked spatial variati

124 ings suggest that synergistic alterations of gut microbial consortia, rather than individual antimicr

125 emonstrate that Kac is widely distributed in gut microbial metabolic pathways, including anaerobic fe

126 how epithelial host responses intersect with gut microbial metabolism in the context of gut inflammat

127 sal link to CVD for these and other specific gut microbial metabolites/pathways has been shown throug

128 ductive hormone concentrations contribute to gut microbial shifts during pregnancy.

129 -inducing capacity of a diverse set of human gut microbial strains by monocolonizing mice with each s

130 A gut-microbial metabolite, trimethylamine N-oxide (TMAO),

131 r, until now, the mediators derived from the gut microbiome affecting the gut-immune-brain axis and t

132 umans encode ~30 amyloidogenic proteins, the gut microbiome also produces functional amyloids.

133 Gut microbiome alterations correlated with model for end

134 Future studies should consider MSM status in gut microbiome analyses.

135 e the association between the infant/toddler gut microbiome and ASD-related social behaviors at age 3

136 ults enhance our understanding of the kogiid gut microbiome and may provide useful information for sy

137 ur results revealed an overall alteration in gut microbiome and metabolites in association with SE in

138 t of coronavirus disease 19 infection on the gut microbiome and on the gut epithelium.

139 The roles of ageing, sex, the gut microbiome and organ transplantation in this complex

140 osensory pain, but any relationships between gut microbiome and PN in obesity have yet to be explored

141 s produce favorable changes in the commensal gut microbiome and reduce host vulnerability to stress-i

142 farm environments on temporal changes in the gut microbiome and resistome of veterinary students with

143 Lifestyle, obesity, and the gut microbiome are important risk factors for metabolic

144 omics analysis, we found a rapid increase in gut microbiome ARG richness and abundance in women from

145 Prior works that have examined the gut microbiome as a novel biomarker for advanced fibrosi

146 Manipulation of the gut microbiome by transplantation and cohousing demonstr

147 Diet-based therapy to induce changes in the gut microbiome can alter systemic alloimmunity in mice,

148 and age-related diseases may lie in how the gut microbiome communicates with both the intestinal muc

149 We observe significant differences in gut microbiome composition across populations that corre

150 fected animals showed decreased diversity of gut microbiome composition, while the ART group appeared

151 ree expanding taxa as potential mediators of gut microbiome dysbiosis.

152 The gut microbiome has been causally implicated in many immu

153 Pathologic changes to the gut microbiome have recently been linked to somatosensor

154 without exercise, on systemic metabolism and gut microbiome in four groups of mice: (a) no interventi

155 crobes is a major route for establishing the gut microbiome in newborns.

156 We investigated the gut microbiome in patients with cirrhosis encompassing t

157 The human gut microbiome is a collection of bacteria, protozoa, fu

158 Restoration of the gut microbiome is a promising preventive and therapeutic

159 And although the gut microbiome is influenced by HIV infection and may co

160 Studies have demonstrated that the gut microbiome is linked to metabolic health and its alt

161 Our emerging view of the gut microbiome largely focuses on bacteria, while less i

162 Interventions targeting the gut microbiome may be warranted to reduce cardiovascular

163 es the effect of variations within the human gut microbiome on drugs, has already provided important

164 Gut microbiome profiles of 171 Asians with biopsy-proven

165 ogether, our findings show that the maternal gut microbiome promotes fetal thalamocortical axonogenes

166 ght junction dysregulation in IECs, promoted gut microbiome shifts and enhanced intestinal CD8 T cell

167 We identify candidate members of the gut microbiome that elicit a Smarcad1-dependent colitis

168 GCs can be identified from taxa in the adult gut microbiome that have rarely been recognized for side

169 The neonatal gut microbiome undergoes dynamic changes in response to

170 ied a range of factors associated with human gut microbiome variation.

171 rapy following the replenishment of youthful gut microbiome via modulation of immunologic, microbial,

172 Altered gut microbiome was associated with complications of cirr

173 host Fe status, intestinal functionality and gut microbiome were observed between the short-term and

174 Targeting the gut microbiome, butyrate, and its consequences may repre

175 'Dysbiosis' of the maternal gut microbiome, in response to challenges such as infect

176 des have been well-studied nutrients for the gut microbiome, other resources such as nucleic acids an

177 Using survey data of the human gut microbiome, we detected C. difficile colonization an

178 onoid intake modifies the composition of the gut microbiome, which contributes to the metabolism of f

179 was weakly associated with variation in the gut microbiome.

180 Exercise modulates metabolism and the gut microbiome.

181 by Bacteroidetes, the dominant phylum of the gut microbiome.

182 ng intestinal amino acid homeostasis and the gut microbiome.

183 be linked individually to alterations in the gut microbiome.

184 IL-17/IL-22, with concomitant changes in the gut microbiome.

185 s, liver function, hepatic steatosis and the gut microbiome.

186 s from metagenomes from the infant and adult gut microbiome.

187 ay predispose chorioretinitis via an altered gut microbiome.

188 ochemicals, ultimately influencing the brain-gut-microbiome axis of their host, a bidirectional commu

189 ted categories of the enzymes present in the gut microbiomes of each species.

190 However, the gut microbiomes of multiple unrelated healthy individual

191 Gut microbiomes perform crucial roles in host health and

192 lar physiology over time, including genomes, gut microbiomes, blood metabolomes, blood proteomes, cli

193 nded DNA viruses that are prevalent in human gut microbiomes.

194 Comparisons of mammalian gut microbiota across different environmental conditions

195 The gut microbiota affects tissue physiology, metabolism, an

196 mutation and toxicant exposure in producing gut microbiota alteration and neurotoxicity.

197 otentially confounding prior observations of gut microbiota alterations among persons with HIV (PWH).

198 malnutrition (SAM) display immature, altered gut microbiota and have a high mortality risk.

199 orectal epithelial cells but also affect the gut microbiota and host immunity.

200 Abundant links between the gut microbiota and human health indicate that modificati

201 As due to an increasing academic interest of gut microbiota and its metabolism, this newly developed

202 ggest a strong relation between ARB in human gut microbiota and personal medical history.

203 lyses of the complex interaction between the gut microbiota and the brain.

204 ses on therapeutics that aim to modulate the gut microbiota and the gut-liver axis.

205 oss of gut mucosal integrity and an aberrant gut microbiota are proposed mechanisms contributing to c

206 A and IBD, and changes in the composition of gut microbiota are seen in both diseases.

207 apoptotic cells during development and shape gut microbiota assembly after birth.

208 nsitivity (CHS), behavioral disturbances and gut microbiota changes.

209 We examined how gut microbiota characteristics related to use of opioid

210 e observed altered taxonomic compositions of gut microbiota communities upon SIV infection and at dif

211 Altered gut microbiota composition and function have been associ

212 y gut dysfunction, including modification of gut microbiota composition and higher local inflammatory

213 ion in subcutaneous white fat, 3) change the gut microbiota composition, and 4) prevent and reverse o

214 Stroke alters the gut microbiota composition, and in turn, microbiota dysb

215 Gut microbiota data obtained by DNA sequencing are compl

216 e data indicate differential trajectories of gut microbiota development in humans and chimpanzees tha

217 T capsules in adults with obesity results in gut microbiota engraftment in most recipients for at lea

218 The gut microbiota has been associated with colorectal cance

219 d antibiotic-resistant genes (ARGs) in human gut microbiota have significant impact on human health.

220 uggests that omega-3 PUFAs can also modulate gut microbiota impacting WAT function and adiposity.

221 the gut hormone FGF19, versus placebo on the gut microbiota in a prospective, phase 2 study in patien

222 chicory root inulin-type fructans (ITF), on gut microbiota in healthy adults with habitual low dieta

223 The gut microbiota is a critical mediator of nutrition and d

224 The gut microbiota is a vast and diverse microbial community

225 health, the metabolic potential of the human gut microbiota is still poorly understood.

226 -17A, or depletion of the Th17 cell-inducing gut microbiota markedly reduces stress-induced VOEs.

227 ts of antibiotics on the developing neonatal gut microbiota needs to be precisely quantified.

228 y and captured the diversity of the immature gut microbiota over time and in response to intervention

229 Accumulating evidence suggests that gut microbiota plays a role in the pathogenesis of schiz

230 Lean patients demonstrated an altered gut microbiota profile.

231 The gut microbiota synthesize hundreds of molecules, many of

232 e mechanisms of signalling pathways from the gut microbiota to the brain and discuss direct effects t

233 ected tick proteins that modulate the vector gut microbiota towards an environment that favours colon

234 Additionally, gut microbiota transplantation from MIA mice produced be

235 After fermentation by gut microbiota, a ten-fold increase in the antioxidant v

236 Various behaviors, gut microbiota, and fecal metabolome were assessed at 90

237 nisms, particularly postoperative changes in gut microbiota, in facilitating weight loss and resolvin

238 ukin (IL)-22, induced by colonization of the gut microbiota, is crucial for the prevention of CDI in

239 ulates the mucous barrier via alterations in gut microbiota, resulting in either disease onset/exacer

240 Studies have reported "dysbiotic" changes to gut microbiota, such as depletion of gut bacteria that p

241 etic and environmental factors affecting the gut microbiota, the roles of gut microbes and their biop

242 odel of the human intestinal mucus layer and gut microbiota, we used bioreactors inoculated with heal

243 al Peyer's patches (PPs)-which depend on the gut microbiota-are chronic(4), and little is known about

244 ucted from the core members of the fruit fly gut microbiota.

245 ly immunologically reactive component of the gut microbiota.

246 eased mortality and specific modification of gut microbiota.

247 time and targets the core members of the bee gut microbiota.

248 rum antibiotics for 4 weeks to deplete their gut microbiota.

249 zation and taxonomic assignment of the human gut microbiota.

250 An urbanized structure of the airway and gut microbiotas was associated with an increased risk of

251 Loss of immune tolerance to gut microflora is inextricably linked to chronic intesti

252 fore plausible that circuits exist to detect gut microorganisms and relay this information to areas o

253 oochory (i.e., internal transport within the gut) might play a more important role, but only highly r

254 ic epithelial monolayer in an in vitro human gut model system.

255 whereas A. lumbricoides larvae penetrate the gut mucosa and migrate through the liver and lungs befor

256 nd functions of innate cells in the oral and gut mucosa of infants.

257 and T(h)2 cell differentiation were found in gut mucosa of mice nursed by mothers exposed to D pteron

258 Loss of gut mucosal integrity and an aberrant gut microbiota are

259 Gut mucosal microbes evolved closest to the host, develo

260 provided a good approximation of the average gut mucosal microbiome composition, mucosal biopsies all

261 ial colonization and later succession in the gut of human infants are linked to health and disease la

262 cells (ILCs) were depleted in the blood and gut of people with HIV-1, even with effective antiretrov

263 uced amounts of amino acids are found in the guts of conventionally raised mice compared with germ-fr

264 and incorporate perfused vasculature into a gut-on-a-chip (GOC) model that includes HIECs.

265 oids with monocyte-derived macrophages, in a gut-on-a-chip platform to model the human intestine and

266 the promotion of immune-mediated diseases by gut, oral and skin microbiota.

267 Only 0.2% of ingested eggs survived gut passage, yet, given the abundance, diet, and movemen

268 sing by human-associated bacteria, comparing gut pathogens and commensals, and highlights the tension

269 suppression, PHIVs have evidence of altered gut permeability and fungal translocation.

270 umors than Apc(Min/+) mice and had increased gut permeability before tumor development, associated wi

271 tic variants that regulate radiation-induced gut permeability in adult D. melanogaster.

272 l groups demonstrate an especially prolonged gut persistence and high rate of bacteriuria without doc

273 ntral nervous system that, in turn, regulate gut physiology(4).

274 m-positive bacteria and is restricted to the gut, potentiated the RT-induced antitumor immune respons

275 The thick mucus layer of the gut provides a barrier to infiltration of the underlying

276 ree mice, but their presence was restored by gut re-colonization.

277 play in the extraoral organs, including the gut, remains elusive.

278 The effects on the gut resistome, a reservoir of antimicrobial resistance g

279 48 months for analysis of the participants' gut resistome.

280 , side effects that might be eliminated by a gut-restricted distribution.

281 cular bacterial genomes from a complex human gut sample in approximately 10 d, with 2 d of hands-on b

282 However, how immune signals participate in gut sensation and neuroendocrine response remains unclea

283 These are gut sensory epithelial cells, and those that form synaps

284 Bile acids (BAs), metabolites in the gut, signal nutrient availability by activating the G pr

285 Supplementing gut-sterilized p53-mutant mice and p53-mutant organoids

286 lie polarized motor reflexes evoked by local gut stimulation.

287 e effects of a low FODMAP diet on persistent gut symptoms, the intestinal microbiome, and circulating

288 As fumarate is scarce in the gut, the source of this electron acceptor is unclear.

289 eas third and fourth instar kills were first gutted, then processed and carried away piecemeal.

290 nt were confirmed in vivo in mouse liver and gut tissue.

291 ces disruption, and finally safety for human gut tissues.

292 Once ingested, it is up to the gut to make sense of the food's nutritional value.

293 europod cells provide the foundation for the gut to transduce sensory signals from the intestinal mil

294 Sequencing of gut transcripts revealed PE-fed larvae retain an express

295 an antibody against TLR2 had prolonged whole gut transit times; their colonic LMMP had reduced total

296 We performed whole gut transit, bead latency, and geometric center studies.

297 Third, when Xist is deleted in gut using Villin-Cre, female mice remain healthy despite

298 Infant chimpanzee guts were enriched in some of the same taxa prevalent in

299 e, and most HIV-infected cells reside in the gut, where distinct but unknown mechanisms may promote v

300 proliferate within neonatal lymph nodes and gut, where, upon entry, they upregulate T-bet and coexpr

301 ta inhabits various microenvironments of the gut, with some symbiotic bacteria having evolved traits