ライフサイエンスコーパス: gut microbiome

1 une-mediated diseases is an imbalance in the gut microbiome.

2 sity or ETV6-RUNX1 fusion) shaped a distinct gut microbiome.

3 rich foods and VAT could be explained by the gut microbiome.

4 cteria Phascolarctobacterium spp. within the gut microbiome.

5 ht into the contribution of host genotype to gut microbiome.

6 linking genotypes to phenotypes in the human gut microbiome.

7 y in the resilience and functionality of the gut microbiome.

8 ssive effect was completely abolished by the gut microbiome.

9 modulating the structure and function of the gut microbiome.

10 pathways such as the immune response and the gut microbiome.

11 d 16S ribosomal RNA sequencing to assess the gut microbiome.

12 ay predispose chorioretinitis via an altered gut microbiome.

13 olitis, are associated with dysbiosis of the gut microbiome.

14 prototypical Bacteroidetes inhabitant of the gut microbiome.

15 omes can be influenced by the composition of gut microbiome.

16 centuate the effects of GWI by impacting the gut microbiome.

17 plex microbial communities such as the human gut microbiome.

18 bacteriophages to control and manipulate the gut microbiome.

19 of plant secondary metabolites by the human gut microbiome.

20 was weakly associated with variation in the gut microbiome.

21 Exercise modulates metabolism and the gut microbiome.

22 by Bacteroidetes, the dominant phylum of the gut microbiome.

23 ng intestinal amino acid homeostasis and the gut microbiome.

24 be linked individually to alterations in the gut microbiome.

25 IL-17/IL-22, with concomitant changes in the gut microbiome.

26 s, liver function, hepatic steatosis and the gut microbiome.

27 s from metagenomes from the infant and adult gut microbiome.

28 focused specifically around the Pioneer 100 gut microbiomes.

29 iverse ecosystems worldwide, including human gut microbiomes.

30 nded DNA viruses that are prevalent in human gut microbiomes.

31 lds promise for delivery of therapies in the gut microbiome(1).

32 We integrate gut microbiome 16S rRNA amplicon and shotgun metagenomic

33 le(2,3), or those that are influenced by the gut microbiome(4), by lifestyle choices such as smoking(

34 Therefore, our goal was to examine the gut microbiome across varying etiologies of liver diseas

35 r, until now, the mediators derived from the gut microbiome affecting the gut-immune-brain axis and t

36 , the potential benefits of manipulating the gut microbiome after injury is unknown.

37 umans encode ~30 amyloidogenic proteins, the gut microbiome also produces functional amyloids.

38 Gut microbiome alterations correlated with model for end

39 irrhosis, there is lack of information about gut microbiome alterations in ACLF using quantitative me

40 ng biologics, oral desensitization, targeted gut microbiome alterations, and behavior alteration.

41 icrobiota in HFD female offspring indicating gut microbiome alterations.

42 Future studies should consider MSM status in gut microbiome analyses.

43 Gut microbiome analysis was conducted to investigate the

44 tify potential mechanistic links between the gut microbiome and age-related arterial dysfunction, we

45 This enzyme is abundant in the human gut microbiome and also present in prominent bacterial p

46 e the association between the infant/toddler gut microbiome and ASD-related social behaviors at age 3

47 d spatial variation in diet characteristics, gut microbiome and associations between these two ecolog

48 rt consumption may contribute to a favorable gut microbiome and gut health, but few epidemiologic stu

49 red when assessing the impact of diet on the gut microbiome and health.

50 models suggest that interaction between the gut microbiome and IL-17/IL-22-producing cells plays a r

51 perimental animal models show changes in the gut microbiome and immunity of offspring when exposed to

52 induced HMO alterations influence the infant gut microbiome and immunity.

53 e-body endocrinology and disturbances in the gut microbiome and in mitochondrial and metabolic functi

54 the primary interface between the host, the gut microbiome and its external environment.

55 The gut microbiome and its metabolic processes are dynamic s

56 ults enhance our understanding of the kogiid gut microbiome and may provide useful information for sy

57 of one specific area, the association of the gut microbiome and metabolic disorders.

58 ur results revealed an overall alteration in gut microbiome and metabolites in association with SE in

59 (GIT) that is accompanied by changes in the gut microbiome and microbial translocation that contribu

60 for deciphering the chemical biology of the gut microbiome and might advance microbiome-targeted the

61 entions that we hypothesized would alter the gut microbiome and nutrient absorption.

62 t of coronavirus disease 19 infection on the gut microbiome and on the gut epithelium.

63 The roles of ageing, sex, the gut microbiome and organ transplantation in this complex

64 osensory pain, but any relationships between gut microbiome and PN in obesity have yet to be explored

65 s produce favorable changes in the commensal gut microbiome and reduce host vulnerability to stress-i

66 farm environments on temporal changes in the gut microbiome and resistome of veterinary students with

67 tential associations between early-childhood gut microbiome and social behaviors.

68 Both the gut microbiome and systemic innate immunity differ acros

69 nderstanding of the interactions between the gut microbiome and vitamin D, we conduct a cross-section

70 Comparison of students' gut microbiomes and resistomes to farm workers' and envi

71 Despite their low abundance in gut microbiomes and restricted phylogenetic range, all o

72 are extremely important to bioenergy, human gut microbiome, and plant pathogen researches and indust

73 The timing of the appearance of the first gut microbiome, and the consequences for the early life

74 known about the effect of human migration on gut microbiome antibiotic resistance gene (ARG) carriage

75 Lifestyle, obesity, and the gut microbiome are important risk factors for metabolic

76 Our findings indicate that kogiid gut microbiomes are highly diverse and species-specific,

77 interface of the host and pathogen, skin and gut microbiomes are vital components of immunity.

78 in fatty acids, fermentation products of the gut microbiome, are potent and proregenerative modulator

79 omics analysis, we found a rapid increase in gut microbiome ARG richness and abundance in women from

80 emerging data point to perturbations in the gut microbiome as a key regulator of the inflammatory ca

81 Prior works that have examined the gut microbiome as a novel biomarker for advanced fibrosi

82 ference, glycemic status, and changes in the gut microbiome, as measured by metagenomic sequencing an

83 ctors, clinical blood markers, and the human gut microbiome at the population-scale, our results serv

84 ochemicals, ultimately influencing the brain-gut-microbiome axis of their host, a bidirectional commu

85 oxazole prophylaxis in HEU infants decreased gut microbiome beta-diversity and increased antibiotic r

86 lar physiology over time, including genomes, gut microbiomes, blood metabolomes, blood proteomes, cli

87 o be metabolized by single isolates from the gut microbiome, but the extent of this phenomenon is rar

88 Targeting the gut microbiome, butyrate, and its consequences may repre

89 We then manipulated the gut microbiome by feeding birds one of two diets that di

90 Manipulation of the gut microbiome by transplantation and cohousing demonstr

91 To determine how changes in the gut microbiome can alter drug disposition, the pharmacok

92 Diet-based therapy to induce changes in the gut microbiome can alter systemic alloimmunity in mice,

93 e demonstrate that diverse taxa in the mouse gut microbiome can be modified directly with a desired g

94 examine the evidence that BEVs from the host gut microbiome can enter the circulatory system to disse

95 y animals has illuminated how the vertebrate gut microbiome can have diverse and powerful effects on

96 The mammalian gut microbiome can potentially impact host health and di

97 Variation in the human gut microbiome can reflect host lifestyle and behaviors

98 ing and de novo genome assembly of the human gut microbiome can yield draft bacterial genomes without

99 t individuals on the basis of host genetics, gut microbiome, clinical parameters, diet, lifestyle and

100 e, and industrialized and non-industrialized gut microbiome cohorts.

101 and age-related diseases may lie in how the gut microbiome communicates with both the intestinal muc

102 Herein, the roles of CO in host-gut microbiome communication are examined through a disc

103 uggesting the "messenger" role of CO in host-gut microbiome communication.

104 proach to quantify the effect of three human gut microbiome communities on growth and resistance evol

105 ving estimation problems for synthetic human gut microbiome community models.

106 one formers had a significantly less diverse gut microbiome compared with controls.

107 We observe significant differences in gut microbiome composition across populations that corre

108 s from CD patients in remission and assessed gut microbiome composition before and after FMT at the s

109 uring pregnancy caused marked changes in the gut microbiome composition in both mothers and pups at s

110 Gut microbiome composition predicts ANTS positivity with

111 between the aforementioned measurements and gut microbiome composition sequenced from 16S ribosomal

112 ics on Campylobacter jejuni colonization and gut microbiome composition was evaluated using chicken a

113 crobiota in driving inflammation in IBD, the gut microbiome composition was not altered by changes in

114 This study provides new evidence linking gut microbiome composition with growth and carcass trait

115 at while overall reproductive stage affected gut microbiome composition, the observed patterns were d

116 fected animals showed decreased diversity of gut microbiome composition, while the ART group appeared

117 these alterations could be due to changes in gut microbiome composition.

118 need to consider host genetics and baseline gut microbiome composition.

119 prodromal markers of PD are associated with gut microbiome composition.

120 stigated associations of these features with gut microbiome composition.

121 Host genetics influence gut microbiome composition.

122 Cirrhosis is associated with changes in gut microbiome composition.

123 n, gastrointestinal dysfunction, and altered gut microbiome compositions.

124 The metabolic pathways encoded by the human gut microbiome constantly interact with host gene produc

125 sequencing indicated that alterations of the gut microbiome contributed to the observed effects.

126 oblasts and osteoclasts, we examined whether gut microbiome contributes to bone loss in SCD mice.

127 Taken together, the results suggest the gut microbiome contributes to the depression-like behavi

128 Extensive simulations and gut microbiome data applications are conducted to demons

129 Both elevated insulin and gut-microbiome-derived lipopolysaccharide in response to

130 age/region-matched sub-sets, we analysed the gut microbiome differences across five major diseases in

131 Many microbial communities, including the gut microbiome, display intricate spatial organization(3

132 consistency, were major determinants of the gut microbiome diversity and composition.

133 s, but only 3% of those assembled from adult gut microbiomes do.

134 rogestagens, contribute to the shifts in the gut microbiome during pregnancy and lactation.

135 Surprisingly, our understanding of gut microbiome dynamics is limited.

136 Finally, longitudinal analysis of gut microbiome dynamics within individuals showed that d

137 Gut microbiome dysbiosis using ASV prevalence data may o

138 ive of the present study was to determine if gut microbiome dysbiosis was evident in a mouse model of

139 These individuals also displayed gut microbiome dysbiosis, characterized by decreased div

140 ree expanding taxa as potential mediators of gut microbiome dysbiosis.

141 n children and has been linked to early-life gut microbiome dysbiosis.

142 substantial evidence that alterations in the gut microbiome early in life imprint the host gut mucosa

143 trate the cohesiveness of the mammalian host-gut microbiome entity over evolutionary times.

144 Our results suggest that gut microbiome evaluation could assist with infectious r

145 tives of this study were: i) to identify pig gut microbiome features associated with growth and fatne

146 cosa-associated disorders possess a specific gut microbiome fingerprint associated with the compositi

147 The gut microbiome Firmicutes/Bacteroidetes ratio decreased

148 unction, BP, sodium and potassium excretion, gut microbiome, flow cytometry, catecholamines and methy

149 w current research on social context and the gut microbiome, focusing specifically on socioeconomic s

150 Nutrition and the gut microbiome fuel this process to a significant extent

151 The gut microbiome (GMB), comprising the commensal microbial

152 Person-specific factors, such as gut microbiome, had a greater influence (7.1% of varianc

153 The gut microbiome harbors a 'silent reservoir' of antibioti

154 The human gut microbiome harbors hundreds of bacterial species wit

155 The gut microbiome has been causally implicated in many immu

156 The gut microbiome has been implicated in multiple human chr

157 f trimethylamine (TMA) from carnitine in the gut microbiome has been linked to cardiovascular disease

158 gamma-butyrobetaine to trimethylamine by the gut microbiome has been linked to cardiovascular disease

159 The gut microbiome has been shown to influence the response

160 Beneficial modulation of the gut microbiome has high-impact implications not only in

161 ound derived from diet and metabolism by the gut microbiome, has been associated with several chronic

162 Alterations in the gut microbiome have been associated with the severity of

163 Lastly, changes to the gut microbiome have been shown to directly contribute to

164 Pathologic changes to the gut microbiome have recently been linked to somatosensor

165 Herein, we introduce the Gut Microbiome Health Index (GMHI), a biologically-inter

166 Random forest models integrated gut microbiome, host genetics, urine metabolome, measure

167 P data therefore supports a link between the gut microbiome, IL-17/IL-22, and the onset of metabolic

168 Mounting evidence suggests that the gut microbiome impacts brain development and function.

169 erging evidence points to a key role for the gut microbiome in controlling immune responses to vaccin

170 demonstrating a possible causal role for the gut microbiome in dietary energy harvest.

171 without exercise, on systemic metabolism and gut microbiome in four groups of mice: (a) no interventi

172 rrently, our knowledge about the role of the gut microbiome in health and disease relies mainly on di

173 le is known about effect of long-term ART on gut microbiome in HIV-infected children.

174 on using 16S rRNA sequence data of the human gut microbiome in infants from 2 to 12 months of age.

175 tory substances, we assessed the role of the gut microbiome in mediating vulnerability to repeated so

176 ing behavioural and cognitive effects of the gut microbiome in natural populations is an important go

177 crobes is a major route for establishing the gut microbiome in newborns.

178 Alterations of the gut microbiome in Parkinson disease (PD) have been repea

179 We investigated the gut microbiome in patients with cirrhosis encompassing t

180 this review we will discuss the role of the gut microbiome in patients with IBD; our focus will be o

181 to characterize the genetic potential of the gut microbiome in patients with PSC compared with health

182 The gut microbiome in patients with PSC exhibits large funct

183 disruption of spatial networks in the mouse gut microbiome in response to treatment with antibiotics

184 e time, accumulating evidence implicates the gut microbiome in shaping emotional and social cognition

185 tigated the role of bile acids (BAs) and the gut microbiome in the pathogenesis of lean NAFLD.

186 findings shed light on the role of the human gut microbiome in this process.

187 (ABX) cocktail-mediated perturbations of the gut microbiome in two independent transgenic lines, term

188 'Dysbiosis' of the maternal gut microbiome, in response to challenges such as infect

189 t key steps in the development of the infant gut microbiome, including its shaping by maternal factor

190 e aimed to assess specific signatures of the gut microbiome, including metabolic profiles, in preterm

191 logical pathways, involving imbalance of the gut microbiome, inflammation, metabolic dysregulation, a

192 and selective reconstitution of the maternal gut microbiome influences fetal neurodevelopment in mice

193 However, it is unclear whether the maternal gut microbiome influences neurodevelopment during critic

194 The human gut microbiome is a collection of bacteria, protozoa, fu

195 The gut microbiome is a malleable microbial community that c

196 Restoration of the gut microbiome is a promising preventive and therapeutic

197 Human gut microbiome is a promising target for managing type 2

198 The gut microbiome is a promising target for the development

199 The gut microbiome is an ecosystem that involves complex int

200 that an antibiotic cocktail (ABX)-perturbed gut microbiome is associated with reduced amyloid-beta (

201 The gut microbiome is constantly changing, from birth throug

202 tudies in human subjects have shown that the gut microbiome is different in patients with IBD compare

203 The gut microbiome is fundamental in neurogenesis processes.

204 The gut microbiome is increasingly implicated in modifying s

205 The gut microbiome is increasingly recognized as an importan

206 And although the gut microbiome is influenced by HIV infection and may co

207 The gut microbiome is known to be sensitive to changes in th

208 Studies have demonstrated that the gut microbiome is linked to metabolic health and its alt

209 host's genome impacts the composition of its gut microbiome is not yet well understood in pigs.

210 increasing attention to the degree that the gut microbiome is proposed by some as a new organ system

211 The gut microbiome is the resident microbial community of th

212 Our emerging view of the gut microbiome largely focuses on bacteria, while less i

213 HLA-A29 would affect the composition of the gut microbiome, leading to a dysbiosis and immune-mediat

214 es, recent primate studies indicate that the gut microbiome may also be a biological mechanism linkin

215 Interventions targeting the gut microbiome may be warranted to reduce cardiovascular

216 The gut microbiome may contribute to asthma protection throu

217 Gut microbiome may contribute to disease progression and

218 role in depression, and suggesting that the gut microbiome may participate in the onset of depressiv

219 t infection by Vibrio cholerae is blocked by gut microbiome-mediated hydrolysis of bile acids.

220 BD + CDI, comparing longitudinal data on the gut microbiome, metabolome, and other measures.

221 rated longitudinal multi-omics data from the gut microbiome, metabolome, host epigenome, and transcri

222 microbial population collectively called the gut microbiome (microbiota).

223 between individuals and demonstrates how the gut microbiome might be used in drug development and per

224 We find that the gut microbiome modulates gut-extrinsic sympathetic neuro

225 hlight the potential role of specific PCs as gut microbiome modulators in either the pathogenesis or

226 py share many common mediators of the infant gut microbiome, notably C difficile colonization.

227 Imbalance, or dysbiosis, of the gut microbiome of infants has been linked to an increase

228 impact on the main source of inoculum in the gut microbiome of newborns.

229 The gut microbiome of nonhuman primates is highly similar to

230 uracy of AcGGM within the complex endogenous gut microbiome of pigs, wherein we resolve 355 metagenom

231 thods, we show that farm exposure shapes the gut microbiome of students, resulting in enrichment of p

232 ted categories of the enzymes present in the gut microbiomes of each species.

233 The gut microbiomes of insomnia patients compared with healt

234 entified genes were detectable in the distal gut microbiomes of most individuals living in northern C

235 However, the gut microbiomes of multiple unrelated healthy individual

236 We characterized the gut microbiomes of stranded dwarf (Kogia sima) and pygmy

237 es the effect of variations within the human gut microbiome on drugs, has already provided important

238 deepen our understanding of the role of the gut microbiome on host health.

239 However, the impact of the gut microbiome on PD risk and potential microbiome-depen

240 des have been well-studied nutrients for the gut microbiome, other resources such as nucleic acids an

241 Gut microbiomes perform crucial roles in host health and

242 senescence, the systemic environment and the gut microbiome, phenotypes of ageing can be slowed suffi

243 Participants' gut microbiome, plasma cytokines, and self-reported slee

244 The human gut microbiome plays a central role in human health, and

245 port to the hypotheses that dysbiosis in the gut microbiome plays a role in GWI and that life-style r

246 Interestingly, gut microbiome predicted 3-month survival with good stab

247 CO on bacteria including CO sensing, and (5) gut microbiome production of CO.

248 erations in energy balance and metabolic and gut microbiome profile.

249 Gut microbiome profiles of 171 Asians with biopsy-proven

250 The gut microbiome profoundly affects human health and disea

251 Mammalian gut microbiomes profoundly influence host fitness, but t

252 ogether, our findings show that the maternal gut microbiome promotes fetal thalamocortical axonogenes

253 We review the development of the gut microbiome, proponents of dysbiosis, and interaction

254 Here, we evaluated the gut microbiome, proteome and metabolome in 88 African-Am

255 e fed HF were returned to a normal diet, the gut microbiome recovered toward normal levels in both co

256 ding insight into one's health status from a gut microbiome sample is an important clinical goal in c

257 ied, with C. fulviceps (a grass-wood-feeder) gut microbiome samples containing more genes related to

258 bolism, whereas N. aquilinus (a wood-feeder) gut microbiome samples were enriched in genes involved i

259 peptides from microbial or human proteins in gut microbiome samples.

260 (2020) employ timestamped gut microbiome sequencing data from human subjects coupl

261 his study provides an integrated analysis of gut microbiome, serum bile acid metabolome, imaging, and

262 ght junction dysregulation in IECs, promoted gut microbiome shifts and enhanced intestinal CD8 T cell

263 The gut microbiome should be thought of as an organ system t

264 , the variable most strongly associated with gut microbiome structure in Cameroonians is the presence

265 Especially in human gut microbiome studies, where collecting clinical sample

266 emonstrates that metabolites produced by the gut microbiome, such as butyrate, can have complex effec

267 The reversibility of the effect of HF on the gut microbiome suggests new avenues for treating GWI thr

268 Unlike alpha-diversity, interindividual gut microbiome taxonomic (mean, -0.11 [95% CI, -.15 to -

269 des a detailed picture of the changes to the gut microbiome that are occurring throughout the course

270 changes in the structure and function of the gut microbiome that conveyed atrazine resistance.

271 We identify candidate members of the gut microbiome that elicit a Smarcad1-dependent colitis

272 GCs can be identified from taxa in the adult gut microbiome that have rarely been recognized for side

273 Our study examines the changes to the gut microbiome that occur during experimental autoimmune

274 is is characterized by marked alterations in gut microbiome that parallel disease stages with maximal

275 acterize longitudinal variation in the swine gut microbiome, the extent to which a host's genome impa

276 Like the gut microbiome, the rhizosphere harbors a complex microb

277 an in vitro screening protocol of the mouse gut microbiome to discover molecules that can selectivel

278 peutic strategies for directly targeting the gut microbiome to improve cardiovascular outcomes.

279 amework for mapping the ability of the human gut microbiome to metabolize small molecule drugs: Micro

280 tudies have examined the contribution of the gut microbiome to the health benefits associated with fl

281 eptides that remodeled the Western diet (WD) gut microbiome toward the low-fat-diet microbiome state.

282 The neonatal gut microbiome undergoes dynamic changes in response to

283 hat the metabolite butyrate, secreted by the gut microbiome, underlies some of the effects of FMT.

284 ied a range of factors associated with human gut microbiome variation.

285 association between human host genotype and gut microbiome variation.

286 rapy following the replenishment of youthful gut microbiome via modulation of immunologic, microbial,

287 re prospectively recruited, and their faecal gut microbiome was assessed using 16S rRNA sequencing (I

288 Altered gut microbiome was associated with complications of cirr

289 The composition of the gut microbiome was determined in mothers and offspring w

290 The C. fulviceps gut microbiome was enriched specifically in genes coding

291 We found that the taxonomic structure of the gut microbiome was significantly altered in the GWI mode

292 to explore potential dynamic changes of the gut microbiome, we characterized gut microbiota in adole

293 Using survey data of the human gut microbiome, we detected C. difficile colonization an

294 ergic neuron loss, colon gene expression and gut microbiome were examined 13 months later.

295 host Fe status, intestinal functionality and gut microbiome were observed between the short-term and

296 mplicon sequence variants (ASV) of the human gut microbiome were used to evaluate if individuals with

297 imilar to trends observed in the obese human gut microbiome, where overfeeding of the microbiome crea

298 research has focussed on the oral, skin, and gut microbiomes, whereas relatively little is known abou

299 onoid intake modifies the composition of the gut microbiome, which contributes to the metabolism of f

300 Stroke alters the gut microbiome, which in turn has considerable impact on