ライフサイエンスコーパス: gut microbiota

1 ly immunologically reactive component of the gut microbiota.

2 zation and taxonomic assignment of the human gut microbiota.

3 highlighting the ecological relevance of the gut microbiota.

4 assessing reproducibility in studies of the gut microbiota.

5 nism and its microenvironment, including the gut microbiota.

6 olapse, is associated with alteration of the gut microbiota.

7 ment approaches based on manipulation of the gut microbiota.

8 ntal factor is the metabolic output of human gut microbiota.

9 ss with the composition and diversity of the gut microbiota.

10 tution in HIV infection independently of the gut microbiota.

11 into RORgamma+ pTregs upon interaction with gut microbiota.

12 tyrate is an abundant metabolite produced by gut microbiota.

13 he genetically primed host immune system and gut microbiota.

14 signaling was linked to inflammation and the gut microbiota.

15 s and the impact these compounds have on the gut microbiota.

16 tivity in bone marrow cells, and altered the gut microbiota.

17 iciency virus-infected children have altered gut microbiota.

18 microbial community, which is referred to as gut microbiota.

19 extent of strain-level diversity in the bee gut microbiota.

20 erations (e.g. family to phyla-level) of the gut microbiota.

21 uced during infection by the presence of the gut microbiota.

22 ilitating the understanding of niches in the gut microbiota.

23 ucted from the core members of the fruit fly gut microbiota.

24 s metabolized to trimethylamine (TMA) by the gut microbiota.

25 be linked to systematic modifications in the gut microbiota.

26 eased mortality and specific modification of gut microbiota.

27 time and targets the core members of the bee gut microbiota.

28 rum antibiotics for 4 weeks to deplete their gut microbiota.

29 effort to develop therapies that target the gut microbiota.

30 ects were at least partially mediated by the gut microbiota.

31 tive, mild TBI (rmTBI) will also disrupt the gut microbiota.

32 ave hypolipidemic effects and effects on the gut microbiota.

33 l burden and specific characteristics of the gut microbiota(2,3).

34 tary fructose is converted to acetate by the gut microbiota(9), and this supplies lipogenic acetyl-Co

35 After fermentation by gut microbiota, a ten-fold increase in the antioxidant v

36 s describing short- and long-term changes in gut microbiota abundances, species residence and return

37 Comparisons of mammalian gut microbiota across different environmental conditions

38 thocyanins can be transported to colon where gut microbiota actively produce anthocyanin metabolites.

39 The gut microbiota affects tissue physiology, metabolism, an

40 mutation and toxicant exposure in producing gut microbiota alteration and neurotoxicity.

41 otentially confounding prior observations of gut microbiota alterations among persons with HIV (PWH).

42 s production, were considerably lower in the gut microbiota among the kidney stone patients compared

43 ing environment can persistently shape their gut microbiota and antibiotic resistome.

44 The gut microbiota and bile acid content were determined in

45 Some public clonotypes are dependent on the gut microbiota and encode antibodies that are reactive t

46 malnutrition (SAM) display immature, altered gut microbiota and have a high mortality risk.

47 water hardness) and internal (cutaneous and gut microbiota and host cell interaction) exposures.

48 orectal epithelial cells but also affect the gut microbiota and host immunity.

49 rces for investigating mechanisms connecting gut microbiota and host pathophysiology.

50 dy facilitated a possible connection between gut microbiota and host stress response, which can be fu

51 Abundant links between the gut microbiota and human health indicate that modificati

52 althy lean donors and their ability to alter gut microbiota and improve metabolic outcomes in patient

53 As due to an increasing academic interest of gut microbiota and its metabolism, this newly developed

54 The gut microbiota and its products impact tissue-resident a

55 Here, the swine gut microbiota and liver transcripts were investigated t

56 se data reinforce the essential link between gut microbiota and metabolic syndrome and suggest that t

57 able bacteria that are mislocalized from the gut microbiota and metabolically adapted to the MAT cont

58 of diet (macronutrients and micronutrients), gut microbiota and mucous barriers (gastrointestinal and

59 d children and assessed associations between gut microbiota and patient characteristics.

60 ggest a strong relation between ARB in human gut microbiota and personal medical history.

61 mice, showed a potential contribution of the gut microbiota and pro-inflammatory immune responses of

62 occurred between host metabolites, resident gut microbiota and Salmonella following inoculation of S

63 ntricate and crucial connections between the gut microbiota and the brain involving multiple biologic

64 lyses of the complex interaction between the gut microbiota and the brain.

65 ses on therapeutics that aim to modulate the gut microbiota and the gut-liver axis.

66 ablishes and quantifies the link between the gut microbiota and the human immune system, with implica

67 Gut microbiota and their metabolites are instrumental in

68 Here, we examine associations between the gut microbiota and ~150 host phenotypic features across

69 s of this treatment on developing HEU infant gut microbiotas and resistomes are largely undefined.

70 ogether with 16S rRNA gene sequencing of the gut microbiota, and faecal and plasma short-chain fatty

71 Various behaviors, gut microbiota, and fecal metabolome were assessed at 90

72 expression in hippocampus, re-structures the gut microbiota, and improves microbial metabolites that

73 findings suggest that insomnia symptomology, gut microbiota, and inflammation may be interrelated in

74 fatty acids, mediates health effects of the gut microbiota, and is a therapeutic target for metaboli

75 loss diets; however, the ways that diet, the gut microbiota, and long-term weight loss influence one

76 ng (RACS) was used to sort MA-ARB from human gut microbiota, and mini-metagenomic DNA of the sorted b

77 it, allow protected polyphenols to reach the gut microbiota, and preserve polyphenol bioactivity.

78 Adult MIA offspring displayed altered gut microbiota, and relative abundance of specific compo

79 but the functional interactions among PLPE, gut microbiota, and the hypoglycemic effect remain uncle

80 We examined the regulatory effect of PLPE on gut microbiota, and the molecular mechanism underlying i

81 ume crystalloid (LV-Cr) resuscitation on the gut microbiota, and to evaluate its' potential relations

82 therapeutic approaches based on knowledge of gut microbiota are needed.

83 tions between the host immune system and the gut microbiota are now attracting emerging interest.

84 oss of gut mucosal integrity and an aberrant gut microbiota are proposed mechanisms contributing to c

85 A and IBD, and changes in the composition of gut microbiota are seen in both diseases.

86 nality, phenotype and heterogeneity of human gut microbiota are still elusive.

87 al Peyer's patches (PPs)-which depend on the gut microbiota-are chronic(4), and little is known about

88 These data highlight the role of the gut microbiota as the main driver of both intra- and int

89 glucose metabolic disorder was caused by the gut microbiota, as confirmed by a broad-spectrum antibio

90 During their first year of life, airway and gut microbiotas, as well as immune marker concentrations

91 apoptotic cells during development and shape gut microbiota assembly after birth.

92 avior, neuropathology and disruptions in the gut microbiota at 0, 45 or 90 days after injury.

93 bidirectional interactions within the brain gut microbiota axis.

94 te and compare the diagnostic performance of gut microbiota-based approaches to simple non-invasive t

95 ) was significantly associated with a richer gut microbiota by alpha diversity.

96 While the knowledge on gut microbiota - C. difficile interactions has improved

97 The deleterious effects of WD on the gut microbiota can be restored after 7 days of dietary p

98 ex bacterial populations that constitute the gut microbiota can harbor antibiotic resistance genes (A

99 is intense interest about whether modulating gut microbiota can impact systemic metabolism.

100 The gut microbiota can provide the host with dietary nutrien

101 tudy also evaluated the relationship between gut microbiota changes and increased inflammatory cytoki

102 clinical diagnosis of UC and associates with gut microbiota changes.

103 nsitivity (CHS), behavioral disturbances and gut microbiota changes.

104 We examined how gut microbiota characteristics related to use of opioid

105 ine colonizing strain and conserved in human gut microbiota, collectively facilitating the understand

106 s exposed to radionuclides host more similar gut microbiota communities that are temporally stable, p

107 e observed altered taxonomic compositions of gut microbiota communities upon SIV infection and at dif

108 dividual differences) and temporally dynamic gut microbiota communities, presumably tracking the natu

109 Thus, our data suggest that the gut microbiota community of obesity-prone mice may regul

110 contributes to the HFD-induced disruption of gut microbiota composition and alpha-defensin expression

111 was to determine the possible role of NT in gut microbiota composition and alpha-defensin gene expre

112 Altered gut microbiota composition and function have been associ

113 y gut dysfunction, including modification of gut microbiota composition and higher local inflammatory

114 Paneth cells are critical in maintaining gut microbiota composition and homeostasis by releasing

115 e of this study was to detect the changes in gut microbiota composition and inflammatory cytokines pr

116 and immune cell profiling, complemented with gut microbiota composition and routine clinical chemistr

117 ns between dietary phenolic compounds (PCs), gut microbiota composition and targeted faecal metabolit

118 al application as a prebiotic for regulating gut microbiota composition in diabetic patients.

119 Overall, gut microbiota composition is strongly associated with b

120 ), and used 16S rRNA sequencing to determine gut microbiota composition pretransplantation and post-t

121 ion in subcutaneous white fat, 3) change the gut microbiota composition, and 4) prevent and reverse o

122 Stroke alters the gut microbiota composition, and in turn, microbiota dysb

123 that the fate of this starch depends on the gut microbiota composition.

124 that the abnormalities in the composition of gut microbiota contribute to the pathogenesis of schizop

125 ed ob/ob and lean mice to investigate if the gut microbiota contributed to these phenotypes.

126 The gut microbiota contributes to host physiology through th

127 increasing evidence suggests that disturbed gut microbiota contributes to their immunopathogenesis.

128 sibility that dietary induced changes in the gut microbiota could be an important mechanism underlyin

129 Gut microbiota data obtained by DNA sequencing are compl

130 proof of principle to a previously published gut microbiota dataset.

131 PAGln thus represents a new CVD-promoting gut microbiota-dependent metabolite that signals via adr

132 nd, more recently, phenylacetylglutamine are gut microbiota-dependent metabolites whose blood levels

133 microbiota transplantation studies, specific gut microbiota-dependent pathways, and downstream metabo

134 Butyrate is a gut microbiota-derived metabolite able to exert several

135 A gut microbiota-derived metabolite, PAGln, was shown to e

136 Human gut microbiota development has been associated with heal

137 e data indicate differential trajectories of gut microbiota development in humans and chimpanzees tha

138 atistically significant, suggesting that the gut microbiota did not alter the effect of LNS on infant

139 Other bacterial species of the gut microbiota did not follow such patterning (e.g. Turi

140 olved in disease pathogenesis, including the gut microbiota, diet, and their metabolites.

141 he composition of especially airway but also gut microbiotas differed between urban and rural infants

142 We report significant gut microbiota differences in PWH regardless of sex and

143 nuclein and toxins interactions in producing gut microbiota disruption, aberrant gut pro-inflammatory

144 ate that, despite their inherent complexity, gut microbiota dynamics can be characterized by several

145 relationships describing various aspects of gut microbiota dynamics.

146 intestinal epithelial barrier, reversed the gut microbiota dysbiosis and increased the production of

147 Gut microbiota dysbiosis is a consequence as well as a d

148 ant to human health status and indicative to gut microbiota dysbiosis.

149 T capsules in adults with obesity results in gut microbiota engraftment in most recipients for at lea

150 abetic nephropathy through modulation of the gut microbiota, enrichment of SCFA-producing bacteria, a

151 revealed the substantial influence that the gut microbiota exert on bee development, food digestion,

152 ved perturbations, such as inflammation, the gut microbiota exhibits resilience and reverts to its or

153 ypothesis that structural differences in the gut microbiota explain a portion of variability in weigh

154 idant capacity of melanoidins is affected by gut microbiota fermentation.

155 B) in situ at the single-cell level in human gut microbiota from two healthy adults.

156 reover, a single metabolite derived from the gut microbiota-gallic acid-could reproduce the entire ef

157 Alterations in gut microbiota (GMB) and host metabolites have been note

158 nvironmental factors, among which, disturbed gut microbiota has attracted increasing attention.

159 The gut microbiota has been associated with colorectal cance

160 Gut microbiota has been implicated in the obesity develo

161 More recently, the gut microbiota has emerged as an important regulator of

162 l microbiota transplantation (FMT) targeting gut microbiota has recently been successfully applied to

163 Alterations in the gut microbiota have been associated with development and

164 between chronic kidney disease (CKD) and the gut microbiota have been postulated, yet questions remai

165 Compositional and functional changes of gut microbiota have been reported in various AIDs, and i

166 d antibiotic-resistant genes (ARGs) in human gut microbiota have significant impact on human health.

167 Gut microbiota have the ability to metabolize glucosinol

168 The human gut microbiota (HGM), which is critical to human health,

169 ds to the development of a hypertensinogenic gut microbiota, hypertension and its complications, and

170 Alterations in gut microbiota impact the pathophysiology of several dis

171 uggests that omega-3 PUFAs can also modulate gut microbiota impacting WAT function and adiposity.

172 , we show that KDs alter the human and mouse gut microbiota in a manner distinct from high-fat diets

173 loosening is associated with changes in the gut microbiota in a preclinical model.

174 the gut hormone FGF19, versus placebo on the gut microbiota in a prospective, phase 2 study in patien

175 nges of the gut microbiome, we characterized gut microbiota in adolescent rats that underwent a fixed

176 4+ counts and may have beneficial effects on gut microbiota in adults.

177 However, modulation of gut microbiota in cancer patients has not been investiga

178 indings have implications for modulating the gut microbiota in cancer treatment.

179 A causal contribution for gut microbiota in CVD has been further supported by a mu

180 t perturbations to normal development of the gut microbiota in early life may contribute to growth fa

181 t the effects of specific metabolites on the gut microbiota in health and disease remain largely unkn

182 chicory root inulin-type fructans (ITF), on gut microbiota in healthy adults with habitual low dieta

183 amino acids, polyamines, and metabolites of gut microbiota in HFD female offspring indicating gut mi

184 However, the extent of restoration of gut microbiota in HIV-1 patients with short or long-term

185 We investigated composition of gut microbiota in HIV-infected and -uninfected children

186 ur findings suggest that estrogen alters the gut microbiota in ICR (CrljOri:CD1) mice, particularly A

187 sed environments, to reveal the true role of gut microbiota in influencing the functioning of their h

188 Depletion of gut microbiota in SNF1 mice resulted in the diminished p

189 linkage between liver (dys)function and the gut microbiota in the acute setting of burn injury.

190 nisms, particularly postoperative changes in gut microbiota, in facilitating weight loss and resolvin

191 tive abundance of specific components of the gut microbiota, including Ruminococcaceae, correlated wi

192 The honey bee gut microbiota influences bee health and has become an i

193 The gut microbiota influences development(1-3) and homeostas

194 The gut microbiota is a critical mediator of nutrition and d

195 The gut microbiota is a vast and diverse microbial community

196 investigated whether the composition of the gut microbiota is different between male and female, and

197 The composition of the gut microbiota is influenced by sex hormones and colorec

198 Whether the tacrolimus-induced gut microbiota is involved in the regulation of hypergly

199 The gut microbiota is now widely recognized as a dynamic eco

200 health, the metabolic potential of the human gut microbiota is still poorly understood.

201 Consequently, the gut microbiota is suggested to affect the sleep/wake arc

202 ukin (IL)-22, induced by colonization of the gut microbiota, is crucial for the prevention of CDI in

203 s and validated the technique on three novel gut microbiota isolates from three distinct phyla.

204 Measures altering gut microbiota like oral intake of probiotics or berberi

205 identify KD-specific changes to the gut microbiota linked to a reduction in pro-inflammatory

206 data demonstrate that BFM induces changes in gut microbiota linked with attenuation of endothelial dy

207 I) is known to involve the disruption of the gut microbiota, little is understood regarding how mucus

208 -17A, or depletion of the Th17 cell-inducing gut microbiota markedly reduces stress-induced VOEs.

209 This finding suggests that the gut microbiota may contribute to the adverse effects of

210 uronal, and metabolic mechanisms for how the gut microbiota may modulate risk for NDs.

211 Gut microbiota may serve as an important indicator for a

212 The involvement of host immunity in the gut microbiota-mediated colonization resistance to Clost

213 The gut microbiota metabolises primary BAs to secondary BAs,

214 e, prolonged labor and breastfeeding; infant gut microbiota, metabolites, and IgA; and childhood body

215 The gut microbiota metabolizes drugs and alters their effica

216 We tested whether the gut microbiota modulates antitumor immune response follo

217 mplex interactions between host genetics and gut microbiota modulating susceptibility to CNS autoimmu

218 ts of antibiotics on the developing neonatal gut microbiota needs to be precisely quantified.

219 Here, we profile the gut microbiota of 166 wild chimpanzees aged 8 months to

220 nal profile presenting similarities with the gut microbiota of herbivorous and omnivorous hosts, some

221 the impact of a WD on the metabolome and the gut microbiota of male and female mice at 5, 10, and 15

222 Our knowledge about the gut microbiota of pigs is still scarce, despite the impo

223 cuss the potential modulatory effects of the gut microbiota on interactions between the immune system

224 Here we examined the effects of the gut microbiota on sleep/wake regulation.

225 We discuss the effects of the gut microbiota on T cells and glial cells, and their rel

226 , they are not expected to negatively affect gut microbiota or cause antimicrobial resistance.

227 Targeting the gut microbiota or T cell migration may represent therape

228 y and captured the diversity of the immature gut microbiota over time and in response to intervention

229 t the preservation of healthy populations of gut microbiota participates in the beneficial properties

230 his approach would be useful for identifying gut microbiota patterns associated with diet and body co

231 izing taxa and weightings for calculation of gut microbiota PC scores at the genus level, and was exa

232 cells brought about by alterations in early gut microbiota persist into adulthood and are associated

233 However, the gut microbiota plasticity (i.e. variability), was correl

234 findings suggest the potential importance of gut microbiota plasticity for sustained weight-loss.

235 Gut microbiota play an important role in host health.

236 The early life gut microbiota plays a crucial role in regulating and ma

237 Accumulating evidence suggests that gut microbiota plays a role in the pathogenesis of schiz

238 Gut microbiota plays a role in the pathophysiology of me

239 ng evidence suggesting that the imbalance of gut microbiota plays a significant role in the pathogene

240 tively recent findings also suggest that the gut microbiota plays an important role in shaping brain

241 Human gut microbiota plays critical roles in physiology and di

242 Our study identifies the mechanism by which gut microbiota preferentially colonize in tumor sites an

243 Features of the gut microbiota previously identified as being involved i

244 Lean patients demonstrated an altered gut microbiota profile.

245 eneralized sources of heterogeneity in human gut microbiota profiles and also identify human lifestyl

246 have a higher risk of infection and display gut microbiota profiles characteristic of dysfunctional

247 superfamily member 2 (TM6SF2) variants, and gut microbiota profiles in lean and nonlean NAFLD were i

248 ties as well as on metabolomic signatures or gut microbiota profiles.

249 rm-free mice revealed that the KD-associated gut microbiota reduces the levels of intestinal pro-infl

250 ggressiveness) were also associated with the gut microbiota, reinforcing the notion for the existence

251 w interphylum iron metabolism contributes to gut microbiota resilience.

252 ulates the mucous barrier via alterations in gut microbiota, resulting in either disease onset/exacer

253 Early work in rodents highlighted the gut microbiota's importance in metabolic disease, includ

254 tent, severe growth faltering may reduce the gut microbiota's resistance and resilience to diarrhea,

255 A gut microbiota signature has been explored to predict ad

256 Gut microbiota signatures might help to predict advanced

257 ared to control in both germ-free or E. coli gut microbiota states was used to quantitate pathway-spe

258 Studies have reported "dysbiotic" changes to gut microbiota, such as depletion of gut bacteria that p

259 We hypothesized that early-life gut microbiota support the functional organization of ne

260 The gut microbiota synthesize hundreds of molecules, many of

261 roducibility in resolving the members of the gut microbiota that are truly associated with human dise

262 bolites from dietary fiber's fermentation by gut microbiota that can affect differentiation or functi

263 We review changes in the gut microbiota that can promote development or progressi

264 These "elite-survivors" harbored distinct gut microbiota that developed after radiation and protec

265 etic and environmental factors affecting the gut microbiota, the roles of gut microbes and their biop

266 Despite the compositional differences in the gut microbiota, the severity of C. difficile infection (

267 Despite its abundance in the gut microbiota, there is limited recognition that PGN co

268 ity that estrogen could cause changes in the gut microbiota, thereby reducing the risk of developing

269 reased acetate and reduced TMA production by gut microbiota, thus, improving gut integrity and restor

270 he poorly absorbed sterol coprostanol by the gut microbiota to develop a framework for the identifica

271 l systems, and possible contributions by the gut microbiota to neurological disorders.

272 e mechanisms of signalling pathways from the gut microbiota to the brain and discuss direct effects t

273 We then tested the importance of gut microbiota to the SL/vulnerable phenotype.

274 Using one defined anaerobic gut microbiota to track whether microbiota interact with

275 s, revealing a considerable influence of the gut microbiota-together and over time-on systemic immune

276 ected tick proteins that modulate the vector gut microbiota towards an environment that favours colon

277 vated in IBD and have the potential to shift gut microbiota towards an IBD-like composition.

278 ty compromised by SIV infection, improve the gut microbiota towards the healthy compositions and alle

279 Additionally, gut microbiota transplantation from MIA mice produced be

280 Indeed, gut microbiota transplantation studies, specific gut mic

281 epigenetics, mitochondrial dysfunction, the gut microbiota, tryptophan-kynurenine metabolism, the HP

282 ating conditions associated with a disrupted gut microbiota, using the recurrent Clostridioides diffi

283 nt quality as unexpectedly strong sources of gut microbiota variance that differ in distribution betw

284 , breastmilk bacteria contributed to overall gut microbiota variation to a similar extent as other mo

285 Interventions targeting the gut microbiota warrant further investigation as a novel

286 volume, and decreased implant fixation, the gut microbiota was affected.

287 The composition of the gut microbiota was analyzed using 16S rRNA metagenomics

288 d not cause this triad of local effects, the gut microbiota was not affected.

289 An urbanized structure of the airway and gut microbiotas was associated with an increased risk of

290 odel of the human intestinal mucus layer and gut microbiota, we used bioreactors inoculated with heal

291 To understand the impact of ART on the gut microbiota, we used the rhesus macaque model of SIV

292 The effects of fenugreek and HFD on gut microbiota were comprehensively mapped and then stat

293 ibiotic exposure is linked to alterations in gut microbiota, which has been related to risks of vario

294 Murine models suggest that opioids alter the gut microbiota, which may impact opioid tolerance and ps

295 the relative abundance of this strain in the gut microbiota, which was correlated with a reduction in

296 Removing gut microbiota with antibiotics partly abolishes the neu

297 ent can be associated with enrichment of the gut microbiota with Bacteroidetes.

298 cuss how the functional axes interconnecting gut microbiota with NLRs impact the modulation of coliti

299 given ampicillin had altered composition of gut microbiota with reduced abundance of gram-positive b

300 bust and significant effects of fenugreek on gut microbiota, with alterations in both alpha and beta